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Items: 29


A High-Fat/High-Protein, Atkins-Type Diet Exacerbates Clostridioides (Clostridium) difficile Infection in Mice, whereas a High-Carbohydrate Diet Protects.

Mefferd CC, Bhute SS, Phan JR, Villarama JV, Do DM, Alarcia S, Abel-Santos E, Hedlund BP.

mSystems. 2020 Feb 11;5(1). pii: e00765-19. doi: 10.1128/mSystems.00765-19.


Effect of the Synthetic Bile Salt Analog CamSA on the Hamster Model of Clostridium difficile Infection.

Howerton A, Seymour CO, Murugapiran SK, Liao Z, Phan JR, Estrada A, Wagner AJ, Mefferd CC, Hedlund BP, Abel-Santos E.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e02251-17. doi: 10.1128/AAC.02251-17. Print 2018 Oct.


The Design, Synthesis, and Characterizations of Spore Germination Inhibitors Effective against an Epidemic Strain of Clostridium difficile.

Sharma SK, Yip C, Esposito EX, Sharma PV, Simon MP, Abel-Santos E, Firestine SM.

J Med Chem. 2018 Aug 9;61(15):6759-6778. doi: 10.1021/acs.jmedchem.8b00632. Epub 2018 Jul 30.


Inhibitory effect of indole analogs against Paenibacillus larvae, the causal agent of American foulbrood disease.

Alvarado I, Margotta JW, Aoki MM, Flores F, Agudelo F, Michel G, Elekonich MM, Abel-Santos E.

J Insect Sci. 2017 Sep 1;17(5). doi: 10.1093/jisesa/iex080.


ent-Labdane Diterpenoids from the Aerial Parts of Eupatorium obtusissmum.

Castillo QA, Triana J, Eiroa JL, Calcul L, Rivera E, Wojtas L, Padrón JM, Boberieth L, Keramane M, Abel-Santos E, Báez LA, Germosén EA.

J Nat Prod. 2016 Apr 22;79(4):907-13. doi: 10.1021/acs.jnatprod.5b00954. Epub 2016 Mar 29.


Comparison of in vitro methods for the production of Paenibacillus larvae endospores.

Alvarado I, Elekonich MM, Abel-Santos E, Wing HJ.

J Microbiol Methods. 2015 Sep;116:30-2. doi: 10.1016/j.mimet.2015.06.011. Epub 2015 Jun 27.


How enteric pathogens know they hit the sweet spot.

Alvarado I, Abel-Santos E.

Future Microbiol. 2014;9(1):13-6. doi: 10.2217/fmb.13.141.


Fate of ingested Clostridium difficile spores in mice.

Howerton A, Patra M, Abel-Santos E.

PLoS One. 2013 Aug 30;8(8):e72620. doi: 10.1371/journal.pone.0072620. eCollection 2013.


A new strategy for the prevention of Clostridium difficile infection.

Howerton A, Patra M, Abel-Santos E.

J Infect Dis. 2013 May 15;207(10):1498-504. doi: 10.1093/infdis/jit068. Epub 2013 Feb 18.


Requirements for in vitro germination of Paenibacillus larvae spores.

Alvarado I, Phui A, Elekonich MM, Abel-Santos E.

J Bacteriol. 2013 Mar;195(5):1005-11. doi: 10.1128/JB.01958-12. Epub 2012 Dec 21.


Cooperativity and interference of germination pathways in Bacillus anthracis spores.

Luu H, Akoachere M, Patra M, Abel-Santos E.

J Bacteriol. 2011 Aug;193(16):4192-8. doi: 10.1128/JB.05126-11. Epub 2011 Jun 17.


Progesterone analogs influence germination of Clostridium sordellii and Clostridium difficile spores in vitro.

Liggins M, Ramirez N, Magnuson N, Abel-Santos E.

J Bacteriol. 2011 Jun;193(11):2776-83. doi: 10.1128/JB.00058-11. Epub 2011 Apr 8.


Mapping interactions between germinants and Clostridium difficile spores.

Howerton A, Ramirez N, Abel-Santos E.

J Bacteriol. 2011 Jan;193(1):274-82. doi: 10.1128/JB.00980-10. Epub 2010 Oct 22.


Testing nucleoside analogues as inhibitors of Bacillus anthracis spore germination in vitro and in macrophage cell culture.

Alvarez Z, Lee K, Abel-Santos E.

Antimicrob Agents Chemother. 2010 Dec;54(12):5329-36. doi: 10.1128/AAC.01029-10. Epub 2010 Oct 4.


Guidelines for nomenclature assignment of Ger receptors.

Ross CA, Abel-Santos E.

Res Microbiol. 2010 Dec;161(10):830-7. doi: 10.1016/j.resmic.2010.08.002. Epub 2010 Sep 24.


Kinetic evidence for the presence of putative germination receptors in Clostridium difficile spores.

Ramirez N, Liggins M, Abel-Santos E.

J Bacteriol. 2010 Aug;192(16):4215-22. doi: 10.1128/JB.00488-10. Epub 2010 Jun 18.


The Ger receptor family from sporulating bacteria.

Ross C, Abel-Santos E.

Curr Issues Mol Biol. 2010;12(3):147-58. Review.


Dissecting interactions between nucleosides and germination receptors in Bacillus cereus 569 spores.

Dodatko T, Akoachere M, Jimenez N, Alvarez Z, Abel-Santos E.

Microbiology. 2010 Apr;156(Pt 4):1244-1255. doi: 10.1099/mic.0.030270-0. Epub 2009 Dec 24.


Requirements for germination of Clostridium sordellii spores in vitro.

Ramirez N, Abel-Santos E.

J Bacteriol. 2010 Jan;192(2):418-25. doi: 10.1128/JB.01226-09. Epub 2009 Nov 13.


Bacillus cereus spores release alanine that synergizes with inosine to promote germination.

Dodatko T, Akoachere M, Muehlbauer SM, Helfrich F, Howerton A, Ross C, Wysocki V, Brojatsch J, Abel-Santos E.

PLoS One. 2009 Jul 28;4(7):e6398. doi: 10.1371/journal.pone.0006398.


Identification of an in vivo inhibitor of Bacillus anthracis spore germination.

Akoachere M, Squires RC, Nour AM, Angelov L, Brojatsch J, Abel-Santos E.

J Biol Chem. 2007 Apr 20;282(16):12112-8. Epub 2007 Feb 12.


Using siclopps for the discovery of novel antimicrobial peptides and their targets.

Nilsson LO, Louassini M, Abel-Santos E.

Protein Pept Lett. 2005 Nov;12(8):795-9.


Use of inteins for the in vivo production of stable cyclic peptide libraries in E. coli.

Abel-Santos E, Scott CP, Benkovic SJ.

Methods Mol Biol. 2003;205:281-94. No abstract available.


Structural requirements for the biosynthesis of backbone cyclic peptide libraries.

Scott CP, Abel-Santos E, Jones AD, Benkovic SJ.

Chem Biol. 2001 Aug;8(8):801-15.


Creating a dynamic picture of the sliding clamp during T4 DNA polymerase holoenzyme assembly by using fluorescence resonance energy transfer.

Trakselis MA, Alley SC, Abel-Santos E, Benkovic SJ.

Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8368-75.


Tracking sliding clamp opening and closing during bacteriophage T4 DNA polymerase holoenzyme assembly.

Alley SC, Abel-Santos E, Benkovic SJ.

Biochemistry. 2000 Mar 21;39(11):3076-90.


Production of cyclic peptides and proteins in vivo.

Scott CP, Abel-Santos E, Wall M, Wahnon DC, Benkovic SJ.

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13638-43.


Sliding clamp of the bacteriophage T4 polymerase has open and closed subunit interfaces in solution.

Alley SC, Shier VK, Abel-Santos E, Sexton DJ, Soumillion P, Benkovic SJ.

Biochemistry. 1999 Jun 15;38(24):7696-709.


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