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A practical guide to the clinical implementation of biomarkers for subclinical rejection following kidney transplantation.

Naesens M, Friedewald J, Mas V, Kaplan B, Abecassis MM.

Transplantation. 2019 Nov 26. doi: 10.1097/TP.0000000000003064. [Epub ahead of print]


Endovascular Management of Acquired Hepatic Arterial-Portal Venous Malformations.

Riaz A, Vogelzang R, Young V, Gabr A, Ganger D, Abecassis M, Lewandowski RJ, Thornburg B, Salem R, Ivancev K, Resnick S.

Cardiovasc Intervent Radiol. 2019 Nov 25. doi: 10.1007/s00270-019-02380-w. [Epub ahead of print]


A novel murine model of differentiation-mediated cytomegalovirus reactivation from latently infected bone marrow haematopoietic cells.

Liu XF, Swaminathan S, Yan S, Engelmann F, Abbott DA, VanOsdol LA, Heald-Sargent T, Qiu L, Chen Q, Iovane A, Zhang Z, Abecassis MM.

J Gen Virol. 2019 Dec;100(12):1680-1694. doi: 10.1099/jgv.0.001327.


Patients with Persistently Low MELD-Na Scores Continue to be at Risk of Liver Related Death.

Mazumder NR, Atiemo K, Daud A, Kho A, Abecassis M, Levitsky J, Ladner D.

Transplantation. 2019 Oct 21. doi: 10.1097/TP.0000000000002997. [Epub ahead of print]


Preoperative Noncoronary Cardiovascular Assessment and Management of Kidney Transplant Candidates.

Baman JR, Knapper J, Raval Z, Harinstein ME, Friedewald JJ, Maganti K, Cuttica MJ, Abecassis MI, Ali ZA, Gheorghiade M, Flaherty JD.

Clin J Am Soc Nephrol. 2019 Nov 7;14(11):1670-1676. doi: 10.2215/CJN.03640319. Epub 2019 Sep 25. Review.


Discovery and validation of a biomarker model (PRESERVE) predictive of renal outcomes after liver transplantation.

Levitsky J, Asrani SK, Klintmalm G, Schiano T, Moss A, Chavin K, Miller C, Guo K, Zhao L, Jennings LW, Brown M, Armstrong B, Abecassis M.

Hepatology. 2019 Sep 11. doi: 10.1002/hep.30939. [Epub ahead of print]


Levosimendan In Single Ventricle Heart Failure After Longterm Survival Of A Modified Blalock-Taussig Shunt.

Tavares J, Baptista B, Sarmento P, Gonçalves B, Abecassis M.

Rev Port Cir Cardiotorac Vasc. 2019 Apr-Jun;26(2):147-149.


Prognostic Role of Albumin, Bilirubin, and ALBI Scores: Analysis of 1000 Patients with Hepatocellular Carcinoma Undergoing Radioembolization.

Antkowiak M, Gabr A, Das A, Ali R, Kulik L, Ganger D, Moore C, Abecassis M, Katariya N, Mouli S, Mahalingam D, Lewandowski RJ, Salem R, Riaz A.

Cancers (Basel). 2019 Jun 24;11(6). pii: E879. doi: 10.3390/cancers11060879.


Immunometabolism of Phagocytes and Relationships to Cardiac Repair.

Zhang S, Bories G, Lantz C, Emmons R, Becker A, Liu E, Abecassis MM, Yvan-Charvet L, Thorp EB.

Front Cardiovasc Med. 2019 Apr 11;6:42. doi: 10.3389/fcvm.2019.00042. eCollection 2019. Review.


ARRIGE Arrives: Toward the Responsible Use of Genome Editing.

Montoliu L, Merchant J, Hirsch F, Abecassis M, Jouannet P, Baertschi B, Sarrauste de Menthière C, Chneiweiss H.

CRISPR J. 2018 Apr;1:128-129. doi: 10.1089/crispr.2018.29012.mon. No abstract available.


External Validation of a Pretransplant Biomarker Model (REVERSE) Predictive of Renal Recovery After Liver Transplantation.

Levitsky J, Asrani SK, Abecassis M, Ruiz R, Jennings LW, Klintmalm G.

Hepatology. 2019 Oct;70(4):1349-1359. doi: 10.1002/hep.30667. Epub 2019 May 28.


Investigator Assessment of the Utility of the TruGraf Molecular Diagnostic Test in Clinical Practice.

First MR, Peddi VR, Mannon R, Knight R, Marsh CL, Kurian SM, Rice JC, Maluf D, Mandelbrot D, Patel A, David J, Schieve C, Lee D, Lewis P, Friedewald JJ, Abecassis MM, Rose S.

Transplant Proc. 2019 Apr;51(3):729-733. doi: 10.1016/j.transproceed.2018.10.024. Epub 2018 Dec 11.


Application of TruGraf v1: A Novel Molecular Biomarker for Managing Kidney Transplant Recipients With Stable Renal Function.

Marsh CL, Kurian SM, Rice JC, Whisenant TC, David J, Rose S, Schieve C, Lee D, Case J, Barrick B, Peddi VR, Mannon RB, Knight R, Maluf D, Mandelbrot D, Patel A, Friedewald JJ, Abecassis MM, First MR.

Transplant Proc. 2019 Apr;51(3):722-728. doi: 10.1016/j.transproceed.2019.01.054. Epub 2019 Jan 26.


The Hispanic Paradox in Patients With Liver Cirrhosis: Current Evidence From a Large Regional Retrospective Cohort Study.

Atiemo K, Mazumder NR, Caicedo JC, Ganger D, Gordon E, Montag S, Maddur H, VanWagner LB, Goel S, Kho A, Abecassis M, Zhao L, Ladner D.

Transplantation. 2019 Dec;103(12):2531-2538. doi: 10.1097/TP.0000000000002733.


A clinically relevant murine model unmasks a "two-hit" mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant.

Zhang Z, Qiu L, Yan S, Wang JJ, Thomas PM, Kandpal M, Zhao L, Iovane A, Liu XF, Thorp EB, Chen Q, Hummel M, Kanwar YS, Abecassis MM.

Am J Transplant. 2019 Sep;19(9):2421-2433. doi: 10.1111/ajt.15376. Epub 2019 May 14.


Gene expression biomarkers for kidney transplant rejection - The entire landscape.

Friedewald J, Abecassis M, Kurian S.

EBioMedicine. 2019 Apr;42:41. doi: 10.1016/j.ebiom.2019.03.060. Epub 2019 Mar 22. No abstract available.


Prognosticating Survival in Hepatocellular Carcinoma with Elevated Baseline Alpha-fetoprotein Treated with Radioembolization Using a Novel Laboratory Scoring System: Initial Development and Validation.

Ali R, Yang Y, Antkowiak M, Gabr A, Mora R, Abouchaleh N, Al Asadi A, Kulik L, Ganger D, Abecassis M, Kataraya N, Mulcahy M, Benson A, Mahalingam D, Thornburg B, Mouli S, Lewandowski RJ, Salem R, Riaz A.

Cardiovasc Intervent Radiol. 2019 May;42(5):700-711. doi: 10.1007/s00270-019-02191-z. Epub 2019 Mar 1.


Clinical implications for the use of a biomarker for subclinical rejection - Conflating arguments cause a disconnection between the premise and the conclusion.

Friedewald J, Abecassis M.

Am J Transplant. 2019 Jul;19(7):2141-2142. doi: 10.1111/ajt.15327. Epub 2019 Mar 18. No abstract available.


Assessment and management of coronary artery disease in kidney and pancreas transplant candidates.

Knapper JT, Raval Z, Harinstein ME, Friedewald JJ, Skaro AI, Abecassis MI, Ali ZA, Gheorghiade M, Flaherty JD.

J Cardiovasc Med (Hagerstown). 2019 Feb;20(2):51-58. doi: 10.2459/JCM.0000000000000742. Review.


Outcomes of Surgical Resection after Radioembolization for Hepatocellular Carcinoma.

Gabr A, Abouchaleh N, Ali R, Baker T, Caicedo J, Katariya N, Abecassis M, Riaz A, Lewandowski RJ, Salem R.

J Vasc Interv Radiol. 2018 Nov;29(11):1502-1510.e1. doi: 10.1016/j.jvir.2018.06.027. Epub 2018 Sep 27.


Development and clinical validity of a novel blood-based molecular biomarker for subclinical acute rejection following kidney transplant.

Friedewald JJ, Kurian SM, Heilman RL, Whisenant TC, Poggio ED, Marsh C, Baliga P, Odim J, Brown MM, Ikle DN, Armstrong BD, Charette JI, Brietigam SS, Sustento-Reodica N, Zhao L, Kandpal M, Salomon DR, Abecassis MM; Clinical Trials in Organ Transplantation 08 (CTOT-08).

Am J Transplant. 2019 Jan;19(1):98-109. doi: 10.1111/ajt.15011. Epub 2018 Aug 31.


Response to "Shifting the conversation on outcomes reporting".

Peipert JD, Abecassis MMI, Butt Z, Cella D, Ladner DP.

Am J Transplant. 2018 Sep;18(9):2368-2369. doi: 10.1111/ajt.14968. Epub 2018 Jun 28. No abstract available.


Radiation Segmentectomy: Potential Curative Therapy for Early Hepatocellular Carcinoma.

Lewandowski RJ, Gabr A, Abouchaleh N, Ali R, Al Asadi A, Mora RA, Kulik L, Ganger D, Desai K, Thornburg B, Mouli S, Hickey R, Caicedo JC, Abecassis M, Riaz A, Salem R.

Radiology. 2018 Jun;287(3):1050-1058. doi: 10.1148/radiol.2018171768. Epub 2018 Apr 24.


Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases.

Marrero JA, Kulik LM, Sirlin CB, Zhu AX, Finn RS, Abecassis MM, Roberts LR, Heimbach JK.

Hepatology. 2018 Aug;68(2):723-750. doi: 10.1002/hep.29913. No abstract available.


The "opportunity costs" of kidney transplantation.

Jay CL, Abecassis MM.

Am J Transplant. 2018 May;18(5):1044-1045. doi: 10.1111/ajt.14724. Epub 2018 Apr 6. No abstract available.


Updated follow-up of a tolerance protocol in HLA-identical renal transplant pairs given donor hematopoietic stem cells.

Leventhal JR, Miller J, Mathew JM, Kurian S, Tambur AR, Friedewald J, Charrette J, Abecassis MM.

Hum Immunol. 2018 May;79(5):277-282. doi: 10.1016/j.humimm.2018.01.010. Epub 2018 Feb 1. Review.


Rapid Biolayer Interferometry Measurements of Urinary CXCL9 to Detect Cellular Infiltrates Noninvasively After Kidney Transplantation.

Gandolfini I, Harris C, Abecassis M, Anderson L, Bestard O, Comai G, Cravedi P, Cremaschi E, Duty JA, Florman S, Friedewald J, La Manna G, Maggiore U, Moran T, Piotti G, Purroy C, Jarque M, Nair V, Shapiro R, Reid-Adam J, Heeger PS.

Kidney Int Rep. 2017 Jun 21;2(6):1186-1193. doi: 10.1016/j.ekir.2017.06.010. eCollection 2017 Nov.


Institutional decision to adopt Y90 as primary treatment for hepatocellular carcinoma informed by a 1,000-patient 15-year experience.

Salem R, Gabr A, Riaz A, Mora R, Ali R, Abecassis M, Hickey R, Kulik L, Ganger D, Flamm S, Atassi R, Atassi B, Sato K, Benson AB, Mulcahy MF, Abouchaleh N, Asadi AA, Desai K, Thornburg B, Vouche M, Habib A, Caicedo J, Miller FH, Yaghmai V, Kallini JR, Mouli S, Lewandowski RJ.

Hepatology. 2018 Oct;68(4):1429-1440. doi: 10.1002/hep.29691. Epub 2018 Jan 29.


Incidence and Risk Factors of Intracranial Hemorrhage in Liver Transplant Recipients.

Gallagher TK, Thomas KA, Ladner DP, Ganger D, Sorond FA, Prabhakaran S, Abecassis MM, Fryer JP, Liotta EM.

Transplantation. 2018 Mar;102(3):448-453. doi: 10.1097/TP.0000000000002005.


Advantages of a prospective multidisciplinary approach in transcatheter aortic valve implantation: Eight years of experience.

Costa C, Teles RC, Brito J, Neves JP, Gabriel HM, Abecassis M, Ribeiras R, Abecasis J, Nolasco T, Furstenau MDC, Vale N, Tralhão A, Madeira S, Mesquita J, Saraiva C, Calé R, Almeida M, Aleixo A, Mendes M.

Rev Port Cardiol. 2017 Nov;36(11):809-818. doi: 10.1016/j.repc.2016.11.015. Epub 2017 Nov 15. English, Portuguese.


Pretransplantation Portal Vein Recanalization and Transjugular Intrahepatic Portosystemic Shunt Creation for Chronic Portal Vein Thrombosis: Final Analysis of a 61-Patient Cohort.

Thornburg B, Desai K, Hickey R, Hohlastos E, Kulik L, Ganger D, Baker T, Abecassis M, Caicedo JC, Ladner D, Fryer J, Riaz A, Lewandowski RJ, Salem R.

J Vasc Interv Radiol. 2017 Dec;28(12):1714-1721.e2. doi: 10.1016/j.jvir.2017.08.005. Epub 2017 Oct 17.



VanWagner LB, Ning H, Whitsett M, Levitsky J, Uttal S, Wilkins JT, Abecassis MM, Ladner DP, Skaro AI, Lloyd-Jones DM.

Hepatology. 2017 Dec;66(6):2089-2090. doi: 10.1002/hep.29525. Epub 2017 Nov 6. No abstract available.


Survival Analysis of Advanced HCC Treated with Radioembolization: Comparing Impact of Clinical Performance Status Versus Vascular Invasion/Metastases.

Ali R, Gabr A, Abouchaleh N, Al Asadi A, Mora RA, Kulik L, Abecassis M, Riaz A, Salem R, Lewandowski RJ.

Cardiovasc Intervent Radiol. 2018 Feb;41(2):260-269. doi: 10.1007/s00270-017-1791-1. Epub 2017 Sep 6.


Clinical outcomes of Y90 radioembolization for recurrent hepatocellular carcinoma following curative resection.

Ali R, Riaz A, Gabr A, Abouchaleh N, Mora R, Al Asadi A, Caicedo JC, Abecassis M, Katariya N, Maddur H, Kulik L, Lewandowski RJ, Salem R.

Eur J Nucl Med Mol Imaging. 2017 Dec;44(13):2195-2202. doi: 10.1007/s00259-017-3792-3. Epub 2017 Aug 15.


Fostering responsible research with genome editing technologies: a European perspective.

Chneiweiss H, Hirsch F, Montoliu L, Müller AM, Fenet S, Abecassis M, Merchant J, Baertschi B, Botbol-Baum M, Houghton JA, Kritikos M, Mifsud J, Bartnik E, Rath J, Druml C, Friedrich B, Carvalho AS, Lanzerath D, Saint-Raymond A.

Transgenic Res. 2017 Oct;26(5):709-713. doi: 10.1007/s11248-017-0028-z. Epub 2017 Jul 20.


Epigenetic regulation of cellular and cytomegalovirus genes during myeloid cell development.

Liu XF, Hummel M, Abecassis M.

Intern Med Rev (Wash D C). 2017 Mar;3(3). doi: 10.18103/imr.v3i3.385.


A point-based prediction model for cardiovascular risk in orthotopic liver transplantation: The CAR-OLT score.

VanWagner LB, Ning H, Whitsett M, Levitsky J, Uttal S, Wilkins JT, Abecassis MM, Ladner DP, Skaro AI, Lloyd-Jones DM.

Hepatology. 2017 Dec;66(6):1968-1979. doi: 10.1002/hep.29329. Epub 2017 Nov 6.


Proteoforms in Peripheral Blood Mononuclear Cells as Novel Rejection Biomarkers in Liver Transplant Recipients.

Toby TK, Abecassis M, Kim K, Thomas PM, Fellers RT, LeDuc RD, Kelleher NL, Demetris J, Levitsky J.

Am J Transplant. 2017 Sep;17(9):2458-2467. doi: 10.1111/ajt.14359. Epub 2017 Jun 27.


Pufferfish mortality associated with novel polar marine toxins in Hawaii.

Work TM, Moeller PD, Beauchesne KR, Dagenais J, Breeden R, Rameyer R, Walsh WJ, Abecassis M, Kobayashi DR, Conway C, Winton J.

Dis Aquat Organ. 2017 Mar 6;123(2):87-99. doi: 10.3354/dao03096.


Mortality Risk Factors Among Patients With Cirrhosis and a Low Model for End-Stage Liver Disease Sodium Score (≤15): An Analysis of Liver Transplant Allocation Policy Using Aggregated Electronic Health Record Data.

Atiemo K, Skaro A, Maddur H, Zhao L, Montag S, VanWagner L, Goel S, Kho A, Ho B, Kang R, Holl JL, Abecassis MM, Levitsky J, Ladner DP.

Am J Transplant. 2017 Sep;17(9):2410-2419. doi: 10.1111/ajt.14239. Epub 2017 Apr 4.


Biomarker Guidelines for High-Dimensional Genomic Studies in Transplantation: Adding Method to the Madness.

Kurian SM, Whisenant T, Mas V, Heilman R, Abecassis M, Salomon DR, Moss A, Kaplan B.

Transplantation. 2017 Mar;101(3):457-463. doi: 10.1097/TP.0000000000001622. No abstract available.


Clinical Trials for Immunosuppression in Transplantation: The Case for Reform and Change in Direction.

OʼConnell PJ, Kuypers DR, Mannon RB, Abecassis M, Chadban SJ, Gill JS, Murphy B, Nickerson PW, Schold JD, Stock PG, Seron D, Alloway RR, Bromberg JS, Budde K, Jordan SC, Legendre C, Lefaucheur C, Sarwall M, Segev DL, Stegall MD, Tullius SG, Wong G, Woodle ES, Ascher N, Morris RE.

Transplantation. 2017 Jul;101(7):1527-1534. doi: 10.1097/TP.0000000000001648.


Orthogonal Comparison of Molecular Signatures of Kidney Transplants With Subclinical and Clinical Acute Rejection: Equivalent Performance Is Agnostic to Both Technology and Platform.

Kurian SM, Velazquez E, Thompson R, Whisenant T, Rose S, Riley N, Harrison F, Gelbart T, Friedewald JJ, Charette J, Brietigam S, Peysakhovich J, First MR, Abecassis MM, Salomon DR.

Am J Transplant. 2017 Aug;17(8):2103-2116. doi: 10.1111/ajt.14224. Epub 2017 Apr 3.


AASLD guidelines for the treatment of hepatocellular carcinoma.

Heimbach JK, Kulik LM, Finn RS, Sirlin CB, Abecassis MM, Roberts LR, Zhu AX, Murad MH, Marrero JA.

Hepatology. 2018 Jan;67(1):358-380. doi: 10.1002/hep.29086. No abstract available.


Caveat emptor: the devil is still in the detail.

Abecassis M, Kaplan B.

Nat Rev Nephrol. 2017 Jan;13(1):60. doi: 10.1038/nrneph.2016.161. Epub 2016 Nov 14. No abstract available.


Y90 Radioembolization Significantly Prolongs Time to Progression Compared With Chemoembolization in Patients With Hepatocellular Carcinoma.

Salem R, Gordon AC, Mouli S, Hickey R, Kallini J, Gabr A, Mulcahy MF, Baker T, Abecassis M, Miller FH, Yaghmai V, Sato K, Desai K, Thornburg B, Benson AB, Rademaker A, Ganger D, Kulik L, Lewandowski RJ.

Gastroenterology. 2016 Dec;151(6):1155-1163.e2. doi: 10.1053/j.gastro.2016.08.029. Epub 2016 Aug 27.


Acute Rejection Increases Risk of Graft Failure and Death in Recent Liver Transplant Recipients.

Levitsky J, Goldberg D, Smith AR, Mansfield SA, Gillespie BW, Merion RM, Lok AS, Levy G, Kulik L, Abecassis M, Shaked A.

Clin Gastroenterol Hepatol. 2017 Apr;15(4):584-593.e2. doi: 10.1016/j.cgh.2016.07.035. Epub 2016 Aug 25.


The impact of coronary artery disease on outcomes after liver transplantation.

Skaro AI, Gallon LG, Lyuksemburg V, Jay CL, Zhao L, Ladner DP, VanWagner LB, De Wolf AM, Flaherty JD, Levitsky J, Abecassis MM, Gheorghiade M.

J Cardiovasc Med (Hagerstown). 2016 Dec;17(12):875-885.


Exome Sequencing and Prediction of Long-Term Kidney Allograft Function.

Mesnard L, Muthukumar T, Burbach M, Li C, Shang H, Dadhania D, Lee JR, Sharma VK, Xiang J, Suberbielle C, Carmagnat M, Ouali N, Rondeau E, Friedewald JJ, Abecassis MM, Suthanthiran M, Campagne F.

PLoS Comput Biol. 2016 Sep 29;12(9):e1005088. doi: 10.1371/journal.pcbi.1005088. eCollection 2016 Sep.


Changes in Urinary Microbiome Populations Correlate in Kidney Transplants With Interstitial Fibrosis and Tubular Atrophy Documented in Early Surveillance Biopsies.

Modena BD, Milam R, Harrison F, Cheeseman JA, Abecassis MM, Friedewald JJ, Kirk AD, Salomon DR.

Am J Transplant. 2017 Mar;17(3):712-723. doi: 10.1111/ajt.14038. Epub 2016 Oct 11.

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