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Items: 32


Electroconvulsive shock restores the decreased coverage of brain blood vessels by astrocytic endfeet and ameliorates depressive-like behavior.

Azis IA, Hashioka S, Tsuchie K, Miyaoka T, Abdullah RA, Limoa E, Arauchi R, Inoue K, Miura S, Izuhara M, Kanayama M, Otsuki K, Nagahama M, Kawano K, Araki T, Hayashida M, Wake R, Oh-Nishi A, Tanra AJ, Horiguchi J, Inagaki M.

J Affect Disord. 2019 Jul 4;257:331-339. doi: 10.1016/j.jad.2019.07.008. [Epub ahead of print]


Clostridium butyricum MIYAIRI 588 as Adjunctive Therapy for Treatment-Resistant Major Depressive Disorder: A Prospective Open-Label Trial.

Miyaoka T, Kanayama M, Wake R, Hashioka S, Hayashida M, Nagahama M, Okazaki S, Yamashita S, Miura S, Miki H, Matsuda H, Koike M, Izuhara M, Araki T, Tsuchie K, Azis IA, Arauchi R, Abdullah RA, Oh-Nishi A, Horiguchi J.

Clin Neuropharmacol. 2018 Sep/Oct;41(5):151-155. doi: 10.1097/WNF.0000000000000299.


Gunn rats with glial activation in the hippocampus show prolonged immobility time in the forced swimming test and tail suspension test.

Arauchi R, Hashioka S, Tsuchie K, Miyaoka T, Tsumori T, Limoa E, Azis IA, Oh-Nishi A, Miura S, Otsuki K, Kanayama M, Izuhara M, Nagahama M, Kawano K, Araki T, Liaury K, Abdullah RA, Wake R, Hayashida M, Inoue K, Horiguchi J.

Brain Behav. 2018 Aug;8(8):e01028. doi: 10.1002/brb3.1028. Epub 2018 Jun 28.


Cognitive Behavioral Therapy for Insomnia as Adjunctive Therapy to Antipsychotics in Schizophrenia: A Case Report.

Izuhara M, Matsuda H, Saito A, Hayashida M, Miura S, Oh-Nishi A, Azis IA, Abdullah RA, Tsuchie K, Araki T, Ryousuke A, Kanayama M, Hashioka S, Wake R, Miyaoka T, Horiguchi J.

Front Psychiatry. 2018 Jun 12;9:260. doi: 10.3389/fpsyt.2018.00260. eCollection 2018.


Remission of Psychosis in Treatment-Resistant Schizophrenia following Bone Marrow Transplantation: A Case Report.

Miyaoka T, Wake R, Hashioka S, Hayashida M, Oh-Nishi A, Azis IA, Izuhara M, Tsuchie K, Araki T, Arauchi R, Abdullah RA, Horiguchi J.

Front Psychiatry. 2017 Sep 21;8:174. doi: 10.3389/fpsyt.2017.00174. eCollection 2017.


Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model.

Wilkerson JL, Donvito G, Grim TW, Abdullah RA, Ogasawara D, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2017 Dec;363(3):394-401. doi: 10.1124/jpet.117.243808. Epub 2017 Oct 2.


The endocannabinoid hydrolysis inhibitor SA-57: Intrinsic antinociceptive effects, augmented morphine-induced antinociception, and attenuated heroin seeking behavior in mice.

Wilkerson JL, Ghosh S, Mustafa M, Abdullah RA, Niphakis MJ, Cabrera R, Maldonado RL, Cravatt BF, Lichtman AH.

Neuropharmacology. 2017 Mar 1;114:156-167. doi: 10.1016/j.neuropharm.2016.11.015. Epub 2016 Nov 25.


The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model.

Wilkerson JL, Niphakis MJ, Grim TW, Mustafa MA, Abdullah RA, Poklis JL, Dewey WL, Akbarali H, Banks ML, Wise LE, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2016 Apr;357(1):145-56. doi: 10.1124/jpet.115.229971. Epub 2016 Jan 20.


Endocannabinoid regulation of nausea is mediated by 2-arachidonoylglycerol (2-AG) in the rat visceral insular cortex.

Sticht MA, Limebeer CL, Rafla BR, Abdullah RA, Poklis JL, Ho W, Niphakis MJ, Cravatt BF, Sharkey KA, Lichtman AH, Parker LA.

Neuropharmacology. 2016 Mar;102:92-102. doi: 10.1016/j.neuropharm.2015.10.039. Epub 2015 Nov 2.


Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice.

Ghosh S, Kinsey SG, Liu QS, Hruba L, McMahon LR, Grim TW, Merritt CR, Wise LE, Abdullah RA, Selley DE, Sim-Selley LJ, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2015 Aug;354(2):111-20. doi: 10.1124/jpet.115.222851. Epub 2015 May 21.


HPLC-MS-MS Determination of ZCZ-011, A Novel Pharmacological Tool for Investigation of the Cannabinoid Receptor in Mouse Brain Using Clean Screen FASt™ Column Extraction.

Poklis JL, Clay DJ, Ignatowska-Jankowska BM, Zanato C, Ross RA, Greig IR, Abdullah RA, Mustafa MA, Lichtman AH, Poklis A.

J Anal Toxicol. 2015 Jun;39(5):353-8. doi: 10.1093/jat/bkv015. Epub 2015 Mar 3.


Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation.

Smith TH, Blume LC, Straiker A, Cox JO, David BG, McVoy JR, Sayers KW, Poklis JL, Abdullah RA, Egertová M, Chen CK, Mackie K, Elphick MR, Howlett AC, Selley DE.

Mol Pharmacol. 2015 Apr;87(4):747-65. doi: 10.1124/mol.114.096495. Epub 2015 Feb 5.


Δ9-tetrahydrocannabinol and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation in mice.

Wiebelhaus JM, Grim TW, Owens RA, Lazenka MF, Sim-Selley LJ, Abdullah RA, Niphakis MJ, Vann RE, Cravatt BF, Wiley JL, Negus SS, Lichtman AH.

J Pharmacol Exp Ther. 2015 Feb;352(2):195-207. doi: 10.1124/jpet.114.218677. Epub 2014 Nov 14.


Inhibition of monoacylglycerol lipase reduces nicotine withdrawal.

Muldoon PP, Chen J, Harenza JL, Abdullah RA, Sim-Selley LJ, Cravatt BF, Miles MF, Chen X, Lichtman AH, Damaj MI.

Br J Pharmacol. 2015 Feb;172(3):869-82. doi: 10.1111/bph.12948.


Cannabis use by individuals with multiple sclerosis: effects on specific immune parameters.

Sexton M, Cudaback E, Abdullah RA, Finnell J, Mischley LK, Rozga M, Lichtman AH, Stella N.

Inflammopharmacology. 2014 Oct;22(5):295-303. doi: 10.1007/s10787-014-0214-z. Epub 2014 Aug 19.


Effect of selective inhibition of monoacylglycerol lipase (MAGL) on acute nausea, anticipatory nausea, and vomiting in rats and Suncus murinus.

Parker LA, Niphakis MJ, Downey R, Limebeer CL, Rock EM, Sticht MA, Morris H, Abdullah RA, Lichtman AH, Cravatt BF.

Psychopharmacology (Berl). 2015 Feb;232(3):583-93. doi: 10.1007/s00213-014-3696-x. Epub 2014 Aug 3.


Prolonged monoacylglycerol lipase blockade causes equivalent cannabinoid receptor type 1 receptor-mediated adaptations in fatty acid amide hydrolase wild-type and knockout mice.

Schlosburg JE, Kinsey SG, Ignatowska-Jankowska B, Ramesh D, Abdullah RA, Tao Q, Booker L, Long JZ, Selley DE, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2014 Aug;350(2):196-204. doi: 10.1124/jpet.114.212753. Epub 2014 May 21.


Effects of the fatty acid amide hydrolase inhibitor URB597 on pain-stimulated and pain-depressed behavior in rats.

Kwilasz AJ, Abdullah RA, Poklis JL, Lichtman AH, Negus SS.

Behav Pharmacol. 2014 Apr;25(2):119-29. doi: 10.1097/FBP.0000000000000023.


Attenuation of anticipatory nausea in a rat model of contextually elicited conditioned gaping by enhancement of the endocannabinoid system.

Limebeer CL, Abdullah RA, Rock EM, Imhof E, Wang K, Lichtman AH, Parker LA.

Psychopharmacology (Berl). 2014 Feb;231(3):603-12. doi: 10.1007/s00213-013-3282-7. Epub 2013 Sep 17.


In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects.

Ignatowska-Jankowska BM, Ghosh S, Crowe MS, Kinsey SG, Niphakis MJ, Abdullah RA, Tao Q, O' Neal ST, Walentiny DM, Wiley JL, Cravatt BF, Lichtman AH.

Br J Pharmacol. 2014 Mar;171(6):1392-407. doi: 10.1111/bph.12298.


Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice.

Ramesh D, Gamage TF, Vanuytsel T, Owens RA, Abdullah RA, Niphakis MJ, Shea-Donohue T, Cravatt BF, Lichtman AH.

Neuropsychopharmacology. 2013 May;38(6):1039-49. doi: 10.1038/npp.2012.269. Epub 2013 Jan 3.


Novel insights on the effect of nicotine in a murine colitis model.

AlSharari SD, Akbarali HI, Abdullah RA, Shahab O, Auttachoat W, Ferreira GA, White KL, Lichtman AH, Cabral GA, Damaj MI.

J Pharmacol Exp Ther. 2013 Jan;344(1):207-17. doi: 10.1124/jpet.112.198796. Epub 2012 Oct 31.


Dual fatty acid amide hydrolase and monoacylglycerol lipase blockade produces THC-like Morris water maze deficits in mice.

Wise LE, Long KA, Abdullah RA, Long JZ, Cravatt BF, Lichtman AH.

ACS Chem Neurosci. 2012 May 16;3(5):369-78. doi: 10.1021/cn200130s. Epub 2012 Jan 27.


Production and actions of the anandamide metabolite prostamide E2 in the renal medulla.

Ritter JK, Li C, Xia M, Poklis JL, Lichtman AH, Abdullah RA, Dewey WL, Li PL.

J Pharmacol Exp Ther. 2012 Sep;342(3):770-9. doi: 10.1124/jpet.112.196451. Epub 2012 Jun 8.


Endocannabinoids shape accumbal encoding of cue-motivated behavior via CB1 receptor activation in the ventral tegmentum.

Oleson EB, Beckert MV, Morra JT, Lansink CS, Cachope R, Abdullah RA, Loriaux AL, Schetters D, Pattij T, Roitman MF, Lichtman AH, Cheer JF.

Neuron. 2012 Jan 26;73(2):360-73. doi: 10.1016/j.neuron.2011.11.018.


Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice.

Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH.

J Pharmacol Exp Ther. 2011 Oct;339(1):173-85. doi: 10.1124/jpet.111.181370. Epub 2011 Jun 30.


The fatty acid amide hydrolase (FAAH) inhibitor PF-3845 acts in the nervous system to reverse LPS-induced tactile allodynia in mice.

Booker L, Kinsey SG, Abdullah RA, Blankman JL, Long JZ, Ezzili C, Boger DL, Cravatt BF, Lichtman AH.

Br J Pharmacol. 2012 Apr;165(8):2485-96. doi: 10.1111/j.1476-5381.2011.01445.x.


Association of obesity and hypertension with left ventricular geometry and function in children and adolescents.

Dhuper S, Abdullah RA, Weichbrod L, Mahdi E, Cohen HW.

Obesity (Silver Spring). 2011 Jan;19(1):128-33. doi: 10.1038/oby.2010.134. Epub 2010 Jun 17.


Chronic constriction injury reduces cannabinoid receptor 1 activity in the rostral anterior cingulate cortex of mice.

Hoot MR, Sim-Selley LJ, Poklis JL, Abdullah RA, Scoggins KL, Selley DE, Dewey WL.

Brain Res. 2010 Jun 21;1339:18-25. doi: 10.1016/j.brainres.2010.03.105. Epub 2010 Apr 7.


FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration.

Falenski KW, Thorpe AJ, Schlosburg JE, Cravatt BF, Abdullah RA, Smith TH, Selley DE, Lichtman AH, Sim-Selley LJ.

Neuropsychopharmacology. 2010 Jul;35(8):1775-87. doi: 10.1038/npp.2010.44. Epub 2010 Mar 31.


Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain.

Kinsey SG, Long JZ, O'Neal ST, Abdullah RA, Poklis JL, Boger DL, Cravatt BF, Lichtman AH.

J Pharmacol Exp Ther. 2009 Sep;330(3):902-10. doi: 10.1124/jpet.109.155465. Epub 2009 Jun 5.


Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice.

Schlosburg JE, Carlson BL, Ramesh D, Abdullah RA, Long JZ, Cravatt BF, Lichtman AH.

AAPS J. 2009 Jun;11(2):342-52. doi: 10.1208/s12248-009-9110-7. Epub 2009 May 9.

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