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Items: 31

1.

MicroRNA-4417 is a tumor suppressor and prognostic biomarker for triple-negative breast cancer.

Wong CK, Gromisch C, Ozturk S, Papageorgis P, Abdolmaleky HM, Reinhard BM, Thiagalingam A, Thiagalingam S.

Cancer Biol Ther. 2019;20(8):1113-1120. doi: 10.1080/15384047.2019.1595285. Epub 2019 Mar 28.

PMID:
30922194
2.

Aberrant transcriptomes and DNA methylomes define pathways that drive pathogenesis and loss of brain laterality/asymmetry in schizophrenia and bipolar disorder.

Abdolmaleky HM, Gower AC, Wong CK, Cox JW, Zhang X, Thiagalingam A, Shafa R, Sivaraman V, Zhou JR, Thiagalingam S.

Am J Med Genet B Neuropsychiatr Genet. 2019 Mar;180(2):138-149. doi: 10.1002/ajmg.b.32691. Epub 2018 Nov 23.

PMID:
30468562
3.

Microbiome, inflammation, epigenetic alterations, and mental diseases.

Alam R, Abdolmaleky HM, Zhou JR.

Am J Med Genet B Neuropsychiatr Genet. 2017 Sep;174(6):651-660. doi: 10.1002/ajmg.b.32567. Epub 2017 Jul 10. Review.

PMID:
28691768
4.

Methamphetamine-induced psychosis is associated with DNA hypomethylation and increased expression of AKT1 and key dopaminergic genes.

Nohesara S, Ghadirivasfi M, Barati M, Ghasemzadeh MR, Narimani S, Mousavi-Behbahani Z, Joghataei M, Soleimani M, Taban M, Mehrabi S, Thiagalingam S, Abdolmaleky HM.

Am J Med Genet B Neuropsychiatr Genet. 2016 Dec;171(8):1180-1189. doi: 10.1002/ajmg.b.32506. Epub 2016 Oct 18.

PMID:
27753212
5.

Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia.

Zhang Y, Hodgson NW, Trivedi MS, Abdolmaleky HM, Fournier M, Cuenod M, Do KQ, Deth RC.

PLoS One. 2016 Jan 22;11(1):e0146797. doi: 10.1371/journal.pone.0146797. eCollection 2016.

6.

SDPR functions as a metastasis suppressor in breast cancer by promoting apoptosis.

Ozturk S, Papageorgis P, Wong CK, Lambert AW, Abdolmaleky HM, Thiagalingam A, Cohen HT, Thiagalingam S.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):638-43. doi: 10.1073/pnas.1514663113. Epub 2016 Jan 6.

7.

Tumor Cell-Derived Periostin Regulates Cytokines That Maintain Breast Cancer Stem Cells.

Lambert AW, Wong CK, Ozturk S, Papageorgis P, Raghunathan R, Alekseyev Y, Gower AC, Reinhard BM, Abdolmaleky HM, Thiagalingam S.

Mol Cancer Res. 2016 Jan;14(1):103-13. doi: 10.1158/1541-7786.MCR-15-0079. Epub 2015 Oct 27.

8.

Antipsychotic drugs attenuate aberrant DNA methylation of DTNBP1 (dysbindin) promoter in saliva and post-mortem brain of patients with schizophrenia and Psychotic bipolar disorder.

Abdolmaleky HM, Pajouhanfar S, Faghankhani M, Joghataei MT, Mostafavi A, Thiagalingam S.

Am J Med Genet B Neuropsychiatr Genet. 2015 Dec;168(8):687-96. doi: 10.1002/ajmg.b.32361. Epub 2015 Aug 18.

PMID:
26285059
9.

An update on the epigenetics of psychotic diseases and autism.

Abdolmaleky HM, Zhou JR, Thiagalingam S.

Epigenomics. 2015;7(3):427-49. doi: 10.2217/epi.14.85. Review.

PMID:
26077430
10.

DNA hypermethylation of serotonin transporter gene promoter in drug naïve patients with schizophrenia.

Abdolmaleky HM, Nohesara S, Ghadirivasfi M, Lambert AW, Ahmadkhaniha H, Ozturk S, Wong CK, Shafa R, Mostafavi A, Thiagalingam S.

Schizophr Res. 2014 Feb;152(2-3):373-80. doi: 10.1016/j.schres.2013.12.007. Epub 2014 Jan 8.

PMID:
24411530
11.

Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism.

Muratore CR, Hodgson NW, Trivedi MS, Abdolmaleky HM, Persico AM, Lintas C, De la Monte S, Deth RC.

PLoS One. 2013;8(2):e56927. doi: 10.1371/journal.pone.0056927. Epub 2013 Feb 20.

12.

Flavonoid ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice.

Ni F, Gong Y, Li L, Abdolmaleky HM, Zhou JR.

PLoS One. 2012;7(6):e38802. doi: 10.1371/journal.pone.0038802. Epub 2012 Jun 5.

13.

Tanshinones inhibit the growth of breast cancer cells through epigenetic modification of Aurora A expression and function.

Gong Y, Li Y, Abdolmaleky HM, Li L, Zhou JR.

PLoS One. 2012;7(4):e33656. doi: 10.1371/journal.pone.0033656. Epub 2012 Apr 2.

14.

Bioactive tanshinone I inhibits the growth of lung cancer in part via downregulation of Aurora A function.

Li Y, Gong Y, Li L, Abdolmaleky HM, Zhou JR.

Mol Carcinog. 2013 Jul;52(7):535-43. doi: 10.1002/mc.21888. Epub 2012 Mar 2.

15.

Can the schizophrenia epigenome provide clues for the molecular basis of pathogenesis?

Abdolmaleky HM, Thiagalingam S.

Epigenomics. 2011 Dec;3(6):679-83. doi: 10.2217/epi.11.94. No abstract available.

PMID:
22126286
16.

Emerging roles of epigenetic mechanisms in Parkinson's disease.

Habibi E, Masoudi-Nejad A, Abdolmaleky HM, Haggarty SJ.

Funct Integr Genomics. 2011 Dec;11(4):523-37. doi: 10.1007/s10142-011-0246-z. Epub 2011 Sep 4. Review.

PMID:
21892731
17.

DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder.

Nohesara S, Ghadirivasfi M, Mostafavi S, Eskandari MR, Ahmadkhaniha H, Thiagalingam S, Abdolmaleky HM.

J Psychiatr Res. 2011 Nov;45(11):1432-8. doi: 10.1016/j.jpsychires.2011.06.013. Epub 2011 Aug 5.

PMID:
21820670
18.

Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder.

Ghadirivasfi M, Nohesara S, Ahmadkhaniha HR, Eskandari MR, Mostafavi S, Thiagalingam S, Abdolmaleky HM.

Am J Med Genet B Neuropsychiatr Genet. 2011 Jul;156B(5):536-45. doi: 10.1002/ajmg.b.31192. Epub 2011 May 19.

PMID:
21598376
19.

Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder.

Abdolmaleky HM, Yaqubi S, Papageorgis P, Lambert AW, Ozturk S, Sivaraman V, Thiagalingam S.

Schizophr Res. 2011 Jul;129(2-3):183-90. doi: 10.1016/j.schres.2011.04.007. Epub 2011 May 7.

PMID:
21550210
20.

Smad4 inactivation promotes malignancy and drug resistance of colon cancer.

Papageorgis P, Cheng K, Ozturk S, Gong Y, Lambert AW, Abdolmaleky HM, Zhou JR, Thiagalingam S.

Cancer Res. 2011 Feb 1;71(3):998-1008. doi: 10.1158/0008-5472.CAN-09-3269. Epub 2011 Jan 18.

21.

Smad signaling is required to maintain epigenetic silencing during breast cancer progression.

Papageorgis P, Lambert AW, Ozturk S, Gao F, Pan H, Manne U, Alekseyev YO, Thiagalingam A, Abdolmaleky HM, Lenburg M, Thiagalingam S.

Cancer Res. 2010 Feb 1;70(3):968-78. doi: 10.1158/0008-5472.CAN-09-1872. Epub 2010 Jan 19.

22.

hBub1 negatively regulates p53 mediated early cell death upon mitotic checkpoint activation.

Gao F, Ponte JF, Levy M, Papageorgis P, Cook NM, Ozturk S, Lambert AW, Thiagalingam A, Abdolmaleky HM, Sullivan BA, Thiagalingam S.

Cancer Biol Ther. 2009 Apr;8(7):548-56. Epub 2009 Apr 22.

PMID:
19252416
23.

hBub1 deficiency triggers a novel p53 mediated early apoptotic checkpoint pathway in mitotic spindle damaged cells.

Gao F, Ponte JF, Papageorgis P, Levy M, Ozturk S, Lambert AW, Pan H, Chinnappan D, Cheng KH, Thiagalingam A, Abdolmaleky HM, Thiagalingam S.

Cancer Biol Ther. 2009 Apr;8(7):627-35. Epub 2009 Apr 22.

PMID:
19242126
24.

Epigenetic and pharmacoepigenomic studies of major psychoses and potentials for therapeutics.

Abdolmaleky HM, Zhou JR, Thiagalingam S, Smith CL.

Pharmacogenomics. 2008 Dec;9(12):1809-23. doi: 10.2217/14622416.9.12.1809. Review.

PMID:
19072640
25.

Epigenetic alterations of the dopaminergic system in major psychiatric disorders.

Abdolmaleky HM, Smith CL, Zhou JR, Thiagalingam S.

Methods Mol Biol. 2008;448:187-212. doi: 10.1007/978-1-59745-205-2_9.

PMID:
18370235
26.

Aberrant activation of gamma-catenin promotes genomic instability and oncogenic effects during tumor progression.

Pan H, Gao F, Papageorgis P, Abdolmaleky HM, Faller DV, Thiagalingam S.

Cancer Biol Ther. 2007 Oct;6(10):1638-43. Epub 2007 Aug 17.

PMID:
18245958
27.

Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder.

Abdolmaleky HM, Cheng KH, Faraone SV, Wilcox M, Glatt SJ, Gao F, Smith CL, Shafa R, Aeali B, Carnevale J, Pan H, Papageorgis P, Ponte JF, Sivaraman V, Tsuang MT, Thiagalingam S.

Hum Mol Genet. 2006 Nov 1;15(21):3132-45. Epub 2006 Sep 19.

28.

Genetics and epigenetics in major psychiatric disorders: dilemmas, achievements, applications, and future scope.

Abdolmaleky HM, Thiagalingam S, Wilcox M.

Am J Pharmacogenomics. 2005;5(3):149-60. Review.

PMID:
15952869
29.

Hypermethylation of the reelin (RELN) promoter in the brain of schizophrenic patients: a preliminary report.

Abdolmaleky HM, Cheng KH, Russo A, Smith CL, Faraone SV, Wilcox M, Shafa R, Glatt SJ, Nguyen G, Ponte JF, Thiagalingam S, Tsuang MT.

Am J Med Genet B Neuropsychiatr Genet. 2005 Apr 5;134B(1):60-6.

PMID:
15717292
30.

Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation.

Abdolmaleky HM, Smith CL, Faraone SV, Shafa R, Stone W, Glatt SJ, Tsuang MT.

Am J Med Genet B Neuropsychiatr Genet. 2004 May 15;127B(1):51-9.

PMID:
15108180
31.

Meta-analysis of association between the T102C polymorphism of the 5HT2a receptor gene and schizophrenia.

Abdolmaleky HM, Faraone SV, Glatt SJ, Tsuang MT.

Schizophr Res. 2004 Mar 1;67(1):53-62.

PMID:
14741324

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