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Items: 1 to 50 of 70

1.

Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study.

Averill LA, Abdallah CG, Levey DF, Han S, Harpaz-Rotem I, Kranzler HR, Southwick SM, Krystal JH, Gelernter J, Pietrzak RH.

Depress Anxiety. 2019 Sep;36(9):834-845. doi: 10.1002/da.22912. Epub 2019 Aug 6.

PMID:
31385647
2.

Salience Network Disruption in U.S. Army Soldiers With Posttraumatic Stress Disorder.

Abdallah CG, Averill CL, Ramage AE, Averill LA, Goktas S, Nemati S, Krystal JH, Roache JD, Resick PA, Young-McCaughan S, Peterson AL, Fox P; STRONG STAR Consortium.

Chronic Stress (Thousand Oaks). 2019 Jan-Dec;3. doi: 10.1177/2470547019850467. Epub 2019 May 15.

3.

Reduced Salience and Enhanced Central Executive Connectivity Following PTSD Treatment.

Abdallah CG, Averill CL, Ramage AE, Averill LA, Alkin E, Nemati S, Krystal JH, Roache JD, Resick P, Young-McCaughan S, Peterson AL, Fox P; STRONG STAR Consortium.

Chronic Stress (Thousand Oaks). 2019 Jan-Feb;3. doi: 10.1177/2470547019838971. Epub 2019 Apr 15.

4.

Repeated ketamine infusions for antidepressant-resistant PTSD: Methods of a multicenter, randomized, placebo-controlled clinical trial.

Abdallah CG, Roache JD, Averill LA, Young-McCaughan S, Martini B, Gueorguieva R, Amoroso T, Southwick SM, Guthmiller K, López-Roca AL, Lautenschlager K, Mintz J, Litz BT, Williamson DE, Keane TM, Peterson AL, Krystal JH; Consortium to Alleviate PTSD.

Contemp Clin Trials. 2019 Jun;81:11-18. doi: 10.1016/j.cct.2019.04.009. Epub 2019 Apr 15.

PMID:
30999057
5.

Ketamine: A Paradigm Shift for Depression Research and Treatment.

Krystal JH, Abdallah CG, Sanacora G, Charney DS, Duman RS.

Neuron. 2019 Mar 6;101(5):774-778. doi: 10.1016/j.neuron.2019.02.005. Review.

PMID:
30844397
6.

A Review of fMRI Affective Processing Paradigms Used in the Neurobiological Study of Posttraumatic Stress Disorder.

Negreira AM, Abdallah CG.

Chronic Stress (Thousand Oaks). 2019 Jan-Dec;3. doi: 10.1177/2470547019829035. Epub 2019 Feb 25.

7.

Are There Effective Psychopharmacologic Treatments for PTSD?

Akiki TJ, Abdallah CG.

J Clin Psychiatry. 2018 Dec 18;80(3). pii: 18ac12473. doi: 10.4088/JCP.18ac12473. Review. No abstract available.

8.

Neurobiological studies of trauma-related psychopathology: a public health perspective.

Akiki TJ, Averill LA, Abdallah CG.

Eur J Psychotraumatol. 2018 Dec 20;9(1):1556554. doi: 10.1080/20008198.2018.1556554. eCollection 2018.

9.

Altered White Matter Diffusivity of the Cingulum Angular Bundle in Posttraumatic Stress Disorder.

Averill CL, Averill LA, Wrocklage KM, Scott JC, Akiki TJ, Schweinsburg B, Southwick SM, Krystal JH, Abdallah CG.

Mol Neuropsychiatry. 2018 Oct;4(2):75-82. doi: 10.1159/000490464. Epub 2018 Jul 19.

10.

Topology of brain functional connectivity networks in posttraumatic stress disorder.

Akiki TJ, Averill CL, Wrocklage KM, Scott JC, Averill LA, Schweinsburg B, Alexander-Bloch A, Martini B, Southwick SM, Krystal JH, Abdallah CG.

Data Brief. 2018 Sep 6;20:1658-1675. doi: 10.1016/j.dib.2018.08.198. eCollection 2018 Oct.

11.

Ketamine, but Not the NMDAR Antagonist Lanicemine, Increases Prefrontal Global Connectivity in Depressed Patients.

Abdallah CG, Dutta A, Averill CL, McKie S, Akiki TJ, Averill LA, Deakin JFW.

Chronic Stress (Thousand Oaks). 2018 Jan-Dec;2. doi: 10.1177/2470547018796102. Epub 2018 Sep 21.

12.

The Neurobiology and Pharmacotherapy of Posttraumatic Stress Disorder.

Abdallah CG, Averill LA, Akiki TJ, Raza M, Averill CL, Gomaa H, Adikey A, Krystal JH.

Annu Rev Pharmacol Toxicol. 2019 Jan 6;59:171-189. doi: 10.1146/annurev-pharmtox-010818-021701. Epub 2018 Sep 14.

PMID:
30216745
13.

The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects.

Abdallah CG, De Feyter HM, Averill LA, Jiang L, Averill CL, Chowdhury GMI, Purohit P, de Graaf RA, Esterlis I, Juchem C, Pittman BP, Krystal JH, Rothman DL, Sanacora G, Mason GF.

Neuropsychopharmacology. 2018 Sep;43(10):2154-2160. doi: 10.1038/s41386-018-0136-3. Epub 2018 Jun 28.

14.

Early Life Stress Associated With Increased Striatal N-Acetyl-Aspartate: Cerebrospinal Fluid Corticotropin-Releasing Factor Concentrations, Hippocampal Volume, Body Mass and Behavioral Correlates.

Coplan JD, Lu D, El Sehamy AM, Tang C, Jackowski AP, Abdallah CG, Nemeroff CB, Owens MJ, Mathew SJ, Gorman JM.

Chronic Stress (Thousand Oaks). 2018 Jan-Dec;2. doi: 10.1177/2470547018768450. Epub 2018 Apr 18.

15.

The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?

Abdallah CG, Sanacora G, Duman RS, Krystal JH.

Pharmacol Ther. 2018 Oct;190:148-158. doi: 10.1016/j.pharmthera.2018.05.010. Epub 2018 May 25. Review.

16.

Default mode network abnormalities in posttraumatic stress disorder: A novel network-restricted topology approach.

Akiki TJ, Averill CL, Wrocklage KM, Scott JC, Averill LA, Schweinsburg B, Alexander-Bloch A, Martini B, Southwick SM, Krystal JH, Abdallah CG.

Neuroimage. 2018 Aug 1;176:489-498. doi: 10.1016/j.neuroimage.2018.05.005. Epub 2018 May 3.

17.

Stress Response Modulation Underlying the Psychobiology of Resilience.

Averill LA, Averill CL, Kelmendi B, Abdallah CG, Southwick SM.

Curr Psychiatry Rep. 2018 Mar 28;20(4):27. doi: 10.1007/s11920-018-0887-x. Review.

PMID:
29594808
18.

Neurobiology of the dorsolateral prefrontal cortex in GAD: Aberrant neurometabolic correlation to hippocampus and relationship to anxiety sensitivity and IQ.

Coplan JD, Webler R, Gopinath S, Abdallah CG, Mathew SJ.

J Affect Disord. 2018 Mar 15;229:1-13. doi: 10.1016/j.jad.2017.12.001. Epub 2017 Dec 12.

PMID:
29288871
19.

Locus Coeruleus Hyperactivity in Posttraumatic Stress Disorder: Answers and Questions.

Krystal JH, Abdallah CG, Pietrzak RH, Averill LA, Harpaz-Rotem I, Levy I, Kelmendi B, Southwick SM.

Biol Psychiatry. 2018 Feb 1;83(3):197-199. doi: 10.1016/j.biopsych.2017.09.027. No abstract available.

PMID:
29277190
20.

Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia.

Logue MW, van Rooij SJH, Dennis EL, Davis SL, Hayes JP, Stevens JS, Densmore M, Haswell CC, Ipser J, Koch SBJ, Korgaonkar M, Lebois LAM, Peverill M, Baker JT, Boedhoe PSW, Frijling JL, Gruber SA, Harpaz-Rotem I, Jahanshad N, Koopowitz S, Levy I, Nawijn L, O'Connor L, Olff M, Salat DH, Sheridan MA, Spielberg JM, van Zuiden M, Winternitz SR, Wolff JD, Wolf EJ, Wang X, Wrocklage K, Abdallah CG, Bryant RA, Geuze E, Jovanovic T, Kaufman ML, King AP, Krystal JH, Lagopoulos J, Bennett M, Lanius R, Liberzon I, McGlinchey RE, McLaughlin KA, Milberg WP, Miller MW, Ressler KJ, Veltman DJ, Stein DJ, Thomaes K, Thompson PM, Morey RA.

Biol Psychiatry. 2018 Feb 1;83(3):244-253. doi: 10.1016/j.biopsych.2017.09.006. Epub 2017 Sep 20.

21.

Prefrontal Connectivity and Glutamate Transmission: Relevance to Depression Pathophysiology and Ketamine Treatment.

Abdallah CG, Averill CL, Salas R, Averill LA, Baldwin PR, Krystal JH, Mathew SJ, Mathalon DH.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Oct;2(7):566-574. doi: 10.1016/j.bpsc.2017.04.006.

22.

Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study.

Abdallah CG, Hannestad J, Mason GF, Holmes SE, DellaGioia N, Sanacora G, Jiang L, Matuskey D, Satodiya R, Gasparini F, Lin X, Javitch J, Planeta B, Nabulsi N, Carson RE, Esterlis I.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Jul;2(5):449-456. doi: 10.1016/j.bpsc.2017.03.019. Epub 2017 Apr 6.

23.

Multimodal Investigation of Network Level Effects Using Intrinsic Functional Connectivity, Anatomical Covariance, and Structure-to-Function Correlations in Unmedicated Major Depressive Disorder.

Scheinost D, Holmes SE, DellaGioia N, Schleifer C, Matuskey D, Abdallah CG, Hampson M, Krystal JH, Anticevic A, Esterlis I.

Neuropsychopharmacology. 2018 Apr;43(5):1119-1127. doi: 10.1038/npp.2017.229. Epub 2017 Sep 25.

24.

A Network-Based Neurobiological Model of PTSD: Evidence From Structural and Functional Neuroimaging Studies.

Akiki TJ, Averill CL, Abdallah CG.

Curr Psychiatry Rep. 2017 Sep 19;19(11):81. doi: 10.1007/s11920-017-0840-4. Review.

25.

Posttraumatic Stress Disorder: an integrated overview and neurobiological rationale for pharmacology.

Kelmendi B, Adams TG, Southwick S, Abdallah CG, Krystal JH.

Clin Psychol (New York). 2017 Sep;24(3):281-297. doi: 10.1111/cpsp.12202. Epub 2017 Jul 18.

26.

Combat Exposure Severity is Associated with Reduced Cortical Thickness in Combat Veterans: A Preliminary Report.

Averill LA, Abdallah CG, Pietrzak RH, Averill CL, Southwick SM, Krystal JH, Harpaz-Rotem I.

Chronic Stress (Thousand Oaks). 2017 Jan;1. doi: 10.1177/2470547017724714. Epub 2017 Aug 22.

27.

Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic.

Krystal JH, Abdallah CG, Averill LA, Kelmendi B, Harpaz-Rotem I, Sanacora G, Southwick SM, Duman RS.

Curr Psychiatry Rep. 2017 Aug 26;19(10):74. doi: 10.1007/s11920-017-0829-z. Review.

28.

The Association of PTSD Symptom Severity with Localized Hippocampus and Amygdala Abnormalities.

Akiki TJ, Averill CL, Wrocklage KM, Schweinsburg B, Scott JC, Martini B, Averill LA, Southwick SM, Krystal JH, Abdallah CG.

Chronic Stress (Thousand Oaks). 2017 Feb;1. doi: 10.1177/2470547017724069. Epub 2017 Aug 8.

29.

Chronic Pain and Chronic Stress: Two Sides of the Same Coin?

Abdallah CG, Geha P.

Chronic Stress (Thousand Oaks). 2017 Feb;1. doi: 10.1177/2470547017704763. Epub 2017 Jun 8.

30.

Neurobiology of posttraumatic stress disorder (PTSD): A path from novel pathophysiology to innovative therapeutics.

Abdallah CG, Southwick SM, Krystal JH.

Neurosci Lett. 2017 May 10;649:130-132. doi: 10.1016/j.neulet.2017.04.046. No abstract available.

PMID:
28478864
31.

Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression.

Esterlis I, DellaGioia N, Pietrzak RH, Matuskey D, Nabulsi N, Abdallah CG, Yang J, Pittenger C, Sanacora G, Krystal JH, Parsey RV, Carson RE, DeLorenzo C.

Mol Psychiatry. 2018 Apr;23(4):824-832. doi: 10.1038/mp.2017.58. Epub 2017 Apr 11.

32.

Effects of Acute Confinement Stress-induced Hypothalamic-Pituitary Adrenal Axis Activation and Concomitant Peripheral and Central Transforming Growth Factor-β1 Measures in Nonhuman Primates.

Coplan JD, Gopinath S, Abdallah CG, Margolis J, Chen W, Scharf BA, Rosenblum LA, Batuman OA, Smith EL.

Chronic Stress (Thousand Oaks). 2017 Feb;1. doi: 10.1177/2470547016688693. Epub 2017 Feb 17.

33.

What's the Buzz About Hydroxynorketamine? Is It the History, the Story, the Debate, or the Promise?

Abdallah CG.

Biol Psychiatry. 2017 Apr 15;81(8):e61-e63. doi: 10.1016/j.biopsych.2017.01.002. No abstract available.

34.

Targeting glutamate signalling in depression: progress and prospects.

Murrough JW, Abdallah CG, Mathew SJ.

Nat Rev Drug Discov. 2017 Jul;16(7):472-486. doi: 10.1038/nrd.2017.16. Epub 2017 Mar 17. Review.

PMID:
28303025
35.

Cortical thickness reduction in combat exposed U.S. veterans with and without PTSD.

Wrocklage KM, Averill LA, Cobb Scott J, Averill CL, Schweinsburg B, Trejo M, Roy A, Weisser V, Kelly C, Martini B, Harpaz-Rotem I, Southwick SM, Krystal JH, Abdallah CG.

Eur Neuropsychopharmacol. 2017 May;27(5):515-525. doi: 10.1016/j.euroneuro.2017.02.010. Epub 2017 Mar 6.

36.

The Nucleus Accumbens and Ketamine Treatment in Major Depressive Disorder.

Abdallah CG, Jackowski A, Salas R, Gupta S, Sato JR, Mao X, Coplan JD, Shungu DC, Mathew SJ.

Neuropsychopharmacology. 2017 Jul;42(8):1739-1746. doi: 10.1038/npp.2017.49. Epub 2017 Mar 8.

37.

Anterior hippocampal dysconnectivity in posttraumatic stress disorder: a dimensional and multimodal approach.

Abdallah CG, Wrocklage KM, Averill CL, Akiki T, Schweinsburg B, Roy A, Martini B, Southwick SM, Krystal JH, Scott JC.

Transl Psychiatry. 2017 Feb 28;7(2):e1045. doi: 10.1038/tp.2017.12.

38.

Posttraumatic Stress Disorder and Depression Symptom Severities Are Differentially Associated With Hippocampal Subfield Volume Loss in Combat Veterans.

Averill CL, Satodiya RM, Scott JC, Wrocklage KM, Schweinsburg B, Averill LA, Akiki TJ, Amoroso T, Southwick SM, Krystal JH, Abdallah CG.

Chronic Stress (Thousand Oaks). 2017 Jan-Dec;1. doi: 10.1177/2470547017744538. Epub 2017 Dec 13.

39.

Glutamate dysregulation and glutamatergic therapeutics for PTSD: Evidence from human studies.

Averill LA, Purohit P, Averill CL, Boesl MA, Krystal JH, Abdallah CG.

Neurosci Lett. 2017 May 10;649:147-155. doi: 10.1016/j.neulet.2016.11.064. Epub 2016 Dec 1. Review.

40.

PTSD: from neurobiology to pharmacological treatments.

Kelmendi B, Adams TG, Yarnell S, Southwick S, Abdallah CG, Krystal JH.

Eur J Psychotraumatol. 2016 Nov 8;7:31858. doi: 10.3402/ejpt.v7.31858. eCollection 2016. Review.

41.

Ketamine Treatment and Global Brain Connectivity in Major Depression.

Abdallah CG, Averill LA, Collins KA, Geha P, Schwartz J, Averill C, DeWilde KE, Wong E, Anticevic A, Tang CY, Iosifescu DV, Charney DS, Murrough JW.

Neuropsychopharmacology. 2017 May;42(6):1210-1219. doi: 10.1038/npp.2016.186. Epub 2016 Sep 8.

42.

Reduced global functional connectivity of the medial prefrontal cortex in major depressive disorder.

Murrough JW, Abdallah CG, Anticevic A, Collins KA, Geha P, Averill LA, Schwartz J, DeWilde KE, Averill C, Jia-Wei Yang G, Wong E, Tang CY, Krystal JH, Iosifescu DV, Charney DS.

Hum Brain Mapp. 2016 Sep;37(9):3214-23. doi: 10.1002/hbm.23235. Epub 2016 May 4.

43.

KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS.

Abdallah CG, Adams TG, Kelmendi B, Esterlis I, Sanacora G, Krystal JH.

Depress Anxiety. 2016 Aug;33(8):689-97. doi: 10.1002/da.22501. Epub 2016 Apr 6. Review.

44.

Patterns of anterior versus posterior white matter fractional anistotropy concordance in adult nonhuman primates: Effects of early life stress.

Coplan JD, Kolavennu V, Abdallah CG, Mathew SJ, Perera TD, Pantol G, Carpenter D, Tang C.

J Affect Disord. 2016 Mar 1;192:167-75. doi: 10.1016/j.jad.2015.11.049. Epub 2015 Dec 9.

45.

Glutamate and norepinephrine interaction: Relevance to higher cognitive operations and psychopathology.

Abdallah CG, Averill LA, Krystal JH, Southwick SM, Arnsten AF.

Behav Brain Sci. 2016 Jan;39:e201. doi: 10.1017/S0140525X15001727.

46.

Impact of childhood emotional abuse on neocortical neurometabolites and complex emotional processing in patients with generalized anxiety disorder.

Raparia E, Coplan JD, Abdallah CG, Hof PR, Mao X, Mathew SJ, Shungu DC.

J Affect Disord. 2016 Jan 15;190:414-423. doi: 10.1016/j.jad.2015.09.019. Epub 2015 Oct 23.

PMID:
26551399
47.

A history of early life parental loss or separation is associated with successful cognitive-behavioral therapy in major depressive disorder.

Niciu MJ, Abdallah CG, Fenton LR, Fasula MK, Black A, Anderson GM, Sanacora G.

J Affect Disord. 2015 Nov 15;187:241-4. doi: 10.1016/j.jad.2015.08.026. Epub 2015 Aug 19.

48.

Neurobiology of Maternal Stress: Role of Social Rank and Central Oxytocin in Hypothalamic-Pituitary Adrenal Axis Modulation.

Coplan JD, Karim A, Chandra P, St Germain G, Abdallah CG, Altemus M.

Front Psychiatry. 2015 Jul 7;6:100. doi: 10.3389/fpsyt.2015.00100. eCollection 2015.

49.

Prefrontal cortical GABA abnormalities are associated with reduced hippocampal volume in major depressive disorder.

Abdallah CG, Jackowski A, Sato JR, Mao X, Kang G, Cheema R, Coplan JD, Mathew SJ, Shungu DC.

Eur Neuropsychopharmacol. 2015 Aug;25(8):1082-90. doi: 10.1016/j.euroneuro.2015.04.025. Epub 2015 May 5.

50.

Ketamine as a promising prototype for a new generation of rapid-acting antidepressants.

Abdallah CG, Averill LA, Krystal JH.

Ann N Y Acad Sci. 2015 May;1344:66-77. doi: 10.1111/nyas.12718. Epub 2015 Feb 27. Review.

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