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New Peroxisome Proliferator-Activated Receptor Agonist (GQ-11) Improves Wound Healing in Diabetic Mice.

Silva JC, Pitta MGR, Pitta IR, Koh TJ, Abdalla DSP.

Adv Wound Care (New Rochelle). 2019 Sep 1;8(9):417-428. doi: 10.1089/wound.2018.0911. Epub 2019 Aug 9.


Proinflammatory Action of a New Electronegative Low-Density Lipoprotein Epitope.

Faulin TDES, Kazuma SM, Tripodi GL, Cavalcante MF, Wakasuqui F, Oliveira CLP, Degenhardt MFS, Michaloski J, Giordano RJ, Ketelhuth DFJ, Abdalla DSP.

Biomolecules. 2019 Aug 20;9(8). pii: E386. doi: 10.3390/biom9080386.


Propolis Reduces the Expression of Autophagy-Related Proteins in Chondrocytes under Interleukin-1β Stimulus.

Arias C, Saavedra N, Saavedra K, Alvear M, Cuevas A, Stuchi Maria-Engler S, Abdalla DSP, Salazar LA.

Int J Mol Sci. 2019 Aug 1;20(15). pii: E3768. doi: 10.3390/ijms20153768.


Use of nPSi-βCD Composite Microparticles for the Controlled Release of Caffeic Acid and Pinocembrin, Two Main Polyphenolic Compounds Found in a Chilean Propolis.

Guzmán-Oyarzo D, Plaza T, Recio-Sánchez G, Abdalla DSP, Salazar LA, Hernández-Montelongo J.

Pharmaceutics. 2019 Jun 19;11(6). pii: E289. doi: 10.3390/pharmaceutics11060289.


Effect of oral isotretinoin on the nucleo-cytoplasmic distribution of FoxO1 and FoxO3 proteins in sebaceous glands of patients with acne vulgaris.

Agamia NF, Hussein OM, Abdelmaksoud RE, Abdalla DM, Talaat IM, Zaki EI, El Tawdy A, Melnik BC.

Exp Dermatol. 2018 Dec;27(12):1344-1351. doi: 10.1111/exd.13787. Epub 2018 Oct 17.


Comparison between red wine and isolated trans-resveratrol on the prevention and regression of atherosclerosis in LDLr (-/-) mice.

Chassot LN, Scolaro B, Roschel GG, Cogliati B, Cavalcanti MF, Abdalla DSP, Castro IA.

J Nutr Biochem. 2018 Nov;61:48-55. doi: 10.1016/j.jnutbio.2018.07.014. Epub 2018 Aug 16.


Levels of Pro and Anti-inflammatory Citokynes and C-Reactive Protein in Patients with Chronic Periodontitis Submitted to Nonsurgical Periodontal Treatment

Escobar GF, Abdalla DR, Beghini M, Gotti VB, Rodrigues Junior V, Napimoga MH, Ribeiro BM, Rodrigues DBR, Nogueira RD, Pereira SAL.

Asian Pac J Cancer Prev. 2018 Jul 27;19(7):1927-1933.


Regional Myocardial Perfusion Disturbance in Experimental Chronic Chagas Cardiomyopathy.

Lemos de Oliveira LF, Thackeray JT, Marin Neto JA, Dias Romano MM, Vieira de Carvalho EE, Mejia J, Tanaka DM, Kelly da Silva G, Abdalla DR, Malamut C, Bengel FM, de Lourdes Higuchi M, Schmidt A, Cunha-Neto E, Simões MV.

J Nucl Med. 2018 Sep;59(9):1430-1436. doi: 10.2967/jnumed.117.205450. Epub 2018 Apr 26.


GQ-11: A new PPAR agonist improves obesity-induced metabolic alterations in LDLr-/- mice.

Silva JC, de Oliveira EM, Turato WM, Trossini GHG, Maltarollo VG, Pitta MGR, Pitta IR, de Las Heras B, Boscá L, Rudnicki M, Abdalla DSP.

Int J Obes (Lond). 2018 Jun;42(5):1062-1072. doi: 10.1038/s41366-018-0011-7. Epub 2018 Jan 30.


One-Year Conservative Care Using Sodium Bicarbonate Supplementation Is Associated with a Decrease in Electronegative LDL in Chronic Kidney Disease Patients: A Pilot Study.

Rizzetto F, Mafra D, Barra AB, Pires de Melo G, Abdalla DSP, Leite M Jr.

Cardiorenal Med. 2017 Oct;7(4):334-341. doi: 10.1159/000478733. Epub 2017 Aug 17.


The influence of physical activity in the anti-tumor immune response in experimental breast tumor.

Bianco TM, Abdalla DR, Desidério CS, Thys S, Simoens C, Bogers JP, Murta EFC, Michelin MA.

Immunol Lett. 2017 Oct;190:148-158. doi: 10.1016/j.imlet.2017.08.007. Epub 2017 Aug 14.


Analysis of Knowledge Level in Brazilian Students about Human Papillomavirus Infection and Development of Penile Cancer

Abdalla GK, Fajardo EF, Gomes BB, Bianco TM, Salge AK, Carvalho EE, Dos Reis MM, Abrahão DP, Abdalla DR.

Asian Pac J Cancer Prev. 2017 May 1;18(5):1371-1376.


Bone marrow-derived dendritic cells under influence of experimental breast cancer and physical activity.

Abdalla DR, Gomes BBM, Murta EFC, Michelin MA.

Oncol Lett. 2017 Mar;13(3):1406-1410. doi: 10.3892/ol.2017.5589. Epub 2017 Jan 11.


Chronic administration of the soluble, nonbacterial fraction of kefir attenuates lipid deposition in LDLr-/- mice.

Santanna AF, Filete PF, Lima EM, Porto ML, Meyrelles SS, Vasquez EC, Endringer DC, Lenz D, Abdalla DSP, Pereira TMC, Andrade TU.

Nutrition. 2017 Mar;35:100-105. doi: 10.1016/j.nut.2016.11.001. Epub 2016 Nov 22.


Chronic LPSF/GQ-02 treatment attenuates inflammation and atherosclerosis development in LDLr-/- mice.

Silva AKSE, Gomes FODS, Santos Silva BD, Ribeiro EL, Oliveira AC, Araújo SMDR, de Lima IT, Oliveira AGV, Rudnicki M, Abdalla DSP, Lima MDCA, Pitta IDR, Peixoto CA.

Eur J Pharmacol. 2016 Nov 15;791:622-631. doi: 10.1016/j.ejphar.2016.09.037. Epub 2016 Sep 29.


CTHRSSVVC Peptide as a Possible Early Molecular Imaging Target for Atherosclerosis.

Silva RA, Giordano RJ, Gutierrez PS, Rocha VZ, Rudnicki M, Kee P, Abdalla DS, Puech-Leão P, Caramelli B, Arap W, Pasqualini R, Meneghetti JC, Marques FL, Khoobchandani M, Katti KV, Lugão AB, Kalil J.

Int J Mol Sci. 2016 Aug 24;17(9). pii: E1383. doi: 10.3390/ijms17091383.


Polyphenol-Related Epigenetic Modifications in Osteoarthritis: Current Therapeutic Perspectives.

Arias C, Zambrano T, Abdalla DS, Salazar LA.

Curr Pharm Des. 2016;22(44):6682-6693. doi: 10.2174/1381612822666160720165131. Review.


A nanoformulation containing a scFv reactive to electronegative LDL inhibits atherosclerosis in LDL receptor knockout mice.

Cavalcante MF, Kazuma SM, Bender EA, Adorne MD, Ullian M, Veras MM, Saldiva PH, Maranhão AQ, Guterres SS, Pohlmann AR, Abdalla DS.

Eur J Pharm Biopharm. 2016 Oct;107:120-9. doi: 10.1016/j.ejpb.2016.07.002. Epub 2016 Jul 1.


Polyphenols from Chilean Propolis and Pinocembrin Reduce MMP-9 Gene Expression and Activity in Activated Macrophages.

Saavedra N, Cuevas A, Cavalcante MF, Dörr FA, Saavedra K, Zambrano T, Abdalla DS, Salazar LA.

Biomed Res Int. 2016;2016:6505383. doi: 10.1155/2016/6505383. Epub 2016 Mar 28.


New thiazolidinediones affect endothelial cell activation and angiogenesis.

Rudnicki M, Tripodi GL, Ferrer R, Boscá L, Pitta MG, Pitta IR, Abdalla DS.

Eur J Pharmacol. 2016 Jul 5;782:98-106. doi: 10.1016/j.ejphar.2016.04.038. Epub 2016 Apr 21.


Probiotic Soy Product Supplemented with Isoflavones Improves the Lipid Profile of Moderately Hypercholesterolemic Men: A Randomized Controlled Trial.

Cavallini DC, Manzoni MS, Bedani R, Roselino MN, Celiberto LS, Vendramini RC, de Valdez G, Abdalla DS, Pinto RA, Rosetto D, Valentini SR, Rossi EA.

Nutrients. 2016 Jan 19;8(1). pii: E52. doi: 10.3390/nu8010052.


Acute modification in plasma lipid levels in ultramarathon runners.

Emed LG, Passaglia DG, Guerios ST, João PG, Moser AI, Abdalla DS, Guarita-Souza LC, Mikilita ES, Baena CP, da Costa AB, Faria-Neto JR.

J Sports Sci. 2016 Sep;34(17):1657-61. doi: 10.1080/02640414.2015.1130237. Epub 2015 Dec 29.


New PPARγ partial agonist improves obesity-induced metabolic alterations and atherosclerosis in LDLr(-/-) mice.

Silva JC, César FA, de Oliveira EM, Turato WM, Tripodi GL, Castilho G, Machado-Lima A, de Las Heras B, Boscá L, Rabello MM, Hernandes MZ, Pitta MG, Pitta IR, Passarelli M, Rudnicki M, Abdalla DS.

Pharmacol Res. 2016 Feb;104:49-60. doi: 10.1016/j.phrs.2015.12.010. Epub 2015 Dec 17.


Interleukin-12 in patients with cancer is synthesized by peripheral helper T lymphocytes.

Michelin MA, Montes L, Nomelini RS, Abdalla DR, Aleixo AA, Murta EF.

Oncol Lett. 2015 Sep;10(3):1523-1526. Epub 2015 Jul 8.


The MTHFR C677T Polymorphism Is Related to Plasma Concentration of Oxidized Low-Density Lipoprotein in Adolescents with Cardiovascular Risk Factors.

Morais CC, Alves MC, Augusto EM, Abdalla DS, Horst MA, Cominetti C.

J Nutrigenet Nutrigenomics. 2015;8(3):105-13. doi: 10.1159/000439218. Epub 2015 Oct 1.


Angiogenesis Markers in Gynecological Tumors and Patents for Anti-Angiogenic Approach: Review.

Abdalla DR, Simoens C, Bogers JP, Murta EF, Michelin MA.

Recent Pat Anticancer Drug Discov. 2015;10(3):298-307. Review.


Recent Advances of Radionuclide-Based Molecular Imaging of Atherosclerosis.

Kazuma SM, Sultan D, Zhao Y, Detering L, You M, Luehmann HP, Abdalla DS, Liu Y.

Curr Pharm Des. 2015;21(36):5267-76. Review.


ERK1/2 and HIF1α Are Involved in Antiangiogenic Effect of Polyphenols-Enriched Fraction from Chilean Propolis.

Cuevas A, Saavedra N, Rudnicki M, Abdalla DS, Salazar LA.

Evid Based Complement Alternat Med. 2015;2015:187575. doi: 10.1155/2015/187575. Epub 2015 Aug 10.


AMP-Activated Protein Kinase Interacts with the Peroxisome Proliferator-Activated Receptor Delta to Induce Genes Affecting Fatty Acid Oxidation in Human Macrophages.

Kemmerer M, Finkernagel F, Cavalcante MF, Abdalla DS, Müller R, Brüne B, Namgaladze D.

PLoS One. 2015 Jun 22;10(6):e0130893. doi: 10.1371/journal.pone.0130893. eCollection 2015.


Predictive Potential of Twenty-Two Biochemical Biomarkers for Coronary Artery Disease in Type 2 Diabetes Mellitus.

Pereira EC, Bertolami MC, Faludi AA, Monte O, Xavier HT, Pereira TV, Abdalla DS.

Int J Endocrinol. 2015;2015:146816. doi: 10.1155/2015/146816. Epub 2015 May 18.


Improved nonclinical pharmacokinetics and biodistribution of a new PPAR pan-agonist and COX inhibitor in nanocapsule formulation.

Garcia GM, Oliveira LT, Pitta Ida R, de Lima Mdo C, Vilela JM, Andrade MS, Abdalla DS, Mosqueira VC.

J Control Release. 2015 Jul 10;209:207-18. doi: 10.1016/j.jconrel.2015.04.033. Epub 2015 Apr 27.


Post-transcriptional control of Amblyomin-X on secretion of vascular endothelial growth factor and expression of adhesion molecules in endothelial cells.

Drewes CC, Dias RY, Branco VG, Cavalcante MF, Souza JG, Abdalla DS, Chudzinski-Tavassi AM, Farsky SH.

Toxicon. 2015 Jul;101:1-10. doi: 10.1016/j.toxicon.2015.04.002. Epub 2015 Apr 22.


New indole-thiazolidine attenuates atherosclerosis in LDLr(-/-) mice.

César FA, Rudnicki M, de Las Heras B, Boscá L, Lima MC, Pitta IR, Abdalla DS.

Vascul Pharmacol. 2015 Aug;71:174-80. doi: 10.1016/j.vph.2015.03.009. Epub 2015 Apr 11.


Optimized extraction of a single-chain variable fragment of antibody by using aqueous micellar two-phase systems.

Malpiedi LP, Nerli BB, Taqueda ME, Abdalla DS, Pessoa A Jr.

Protein Expr Purif. 2015 Jul;111:53-60. doi: 10.1016/j.pep.2015.03.014. Epub 2015 Mar 28.


The hypolipidemic and pleiotropic effects of rosuvastatin are not enhanced by its association with zinc and selenium supplementation in coronary artery disease patients: a double blind randomized controlled study.

Sena-Evangelista KC, Pedrosa LF, Paiva MS, Dias PC, Ferreira DQ, Cozzolino SM, Faulin TE, Abdalla DS.

PLoS One. 2015 Mar 18;10(3):e0119830. doi: 10.1371/journal.pone.0119830. eCollection 2015.


HSF-1, HIF-1 and HSP90 expression on recombinant Pichia pastoris under fed-batch fermentation.

Zepeda AB, Figueroa CA, Abdalla DS, Maranhão AQ, Ulloa PH, Pessoa A Jr, Farías JG.

Braz J Microbiol. 2014 Aug 29;45(2):485-90. eCollection 2014.


Biomarkers to evaluate the effects of temperature and methanol on recombinant Pichia pastoris.

Zepeda AB, Figueroa CA, Abdalla DS, Maranhão AQ, Ulloa PH, Pessoa A Jr, Farías JG.

Braz J Microbiol. 2014 Aug 29;45(2):475-83. eCollection 2014.


GFP-SCFV: expression and possible applications as a tool for experimental investigations of atherosclerosis.

Faulin Tdo E, Guilherme DF, Silva AS, Abdalla DS, Hering VR, Politi MJ, Maranhão AQ.

Biotechnol Prog. 2014 Sep-Oct;30(5):1206-13. doi: 10.1002/btpr.1935. Epub 2014 Jun 12.


New strategy to surface functionalization of polymeric nanoparticles: one-pot synthesis of scFv anti-LDL(-)-functionalized nanocapsules.

Bender EA, Cavalcante MF, Adorne MD, Colomé LM, Guterres SS, Abdalla DS, Pohlmann AR.

Pharm Res. 2014 Nov;31(11):2975-87. doi: 10.1007/s11095-014-1392-5. Epub 2014 May 8.


Identification of microRNAs involved in the modulation of pro-angiogenic factors in atherosclerosis by a polyphenol-rich extract from propolis.

Cuevas A, Saavedra N, Cavalcante MF, Salazar LA, Abdalla DS.

Arch Biochem Biophys. 2014 Sep 1;557:28-35. doi: 10.1016/ Epub 2014 Apr 30.


Assessment of the effect of triton X-114 on the physicochemical properties of an antibody fragment.

Malpiedi LP, Nerli BB, Abdalla DS, Pessoa A Jr.

Biotechnol Prog. 2014 May-Jun;30(3):554-61. doi: 10.1002/btpr.1882. Epub 2014 Feb 26.


The beneficial effects of rosuvastatin are independent of zinc supplementation in patients with atherosclerosis.

Dias PCS, Sena-Evangelista KCM, Paiva MSMO, Ferreira DQC, Ururahy MAG, Rezende AA, Abdalla DSP, Pedrosa LFC.

J Trace Elem Med Biol. 2014 Apr;28(2):194-199. doi: 10.1016/j.jtemb.2014.01.003. Epub 2014 Jan 29.


Innate immune response adaptation in mice subjected to administration of DMBA and physical activity.

Abdalla DR, Aleixo AA, Murta EF, Michelin MA.

Oncol Lett. 2014 Mar;7(3):886-890. Epub 2013 Dec 24.


Evaluation of sub-clinical atherosclerosis and plasma levels of minimally modified LDL in patients with ankylosing spondylitis and its correlation with disease activity.

Ceccon FT, Azevedo VF, Engelhorn CA, Abdalla DS, Faulin TE, Guarita-Souza LC, Pecoits-Filho R, Faria-Neto JR.

Rev Bras Reumatol. 2013 Nov-Dec;53(6):470-5. doi: 10.1016/j.rbr.2013.06.002. English, Portuguese.


Placental and umbilical cord macroscopic changes associated with fetal and maternal events in the hypertensive disorders of pregnancy.

Salge AK, Xavier RM, Ramalho WS, Rocha EL, Coelho AS, Guimarães JV, Siqueira KM, Abdalla DR, Michelin MA, Murta EF.

Clin Exp Obstet Gynecol. 2013;40(2):198-202.


Influence of immunotherapy with autologous dendritic cells on innate and adaptive immune response in cancer.

Matias BF, de Oliveira TM, Rodrigues CM, Abdalla DR, Montes L, Murta EF, Michelin MA.

Clin Med Insights Oncol. 2013 Jul 28;7:165-72. doi: 10.4137/CMO.S12268. Print 2013.


Cloning and expression of an anti-LDL(-) single-chain variable fragment, and its inhibitory effect on experimental atherosclerosis.

Kazuma SM, Cavalcante MF, Telles AE, Maranhão AQ, Abdalla DS.

MAbs. 2013 Sep-Oct;5(5):763-75. doi: 10.4161/mabs.25859. Epub 2013 Jul 25.


Modulation of immune function by polyphenols: possible contribution of epigenetic factors.

Cuevas A, Saavedra N, Salazar LA, Abdalla DS.

Nutrients. 2013 Jun 28;5(7):2314-32. doi: 10.3390/nu5072314. Review.


Is plasma alpha-tocopherol associated with electronegative LDL in obese adolescents?

Silva IT, Mello AP, Sanches LB, Abdalla DS, Damasceno NR.

J Nutr Sci Vitaminol (Tokyo). 2013;59(2):100-7.

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