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Items: 40

1.

Transcriptional consequences of impaired immune cell responses induced by cystic fibrosis plasma characterized via dual RNA sequencing.

Ideozu JE, Rangaraj V, Abdala-Valencia H, Zhang X, Kandpal M, Sala MA, Davuluri RV, Levy H.

BMC Med Genomics. 2019 May 22;12(1):66. doi: 10.1186/s12920-019-0529-0.

2.

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis.

Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Reyfman PA, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, Abdala-Valencia H, Chiarella SE, Sun KA, Woods PS, Ghio AJ, Jain M, Perlman H, Ridge KM, Morimoto RI, Sznajder JI, Balch WE, Bhorade SM, Bharat A, Prakriya M, Chandel NS, Mutlu GM, Budinger GRS.

Cell Metab. 2019 Feb 5;29(2):503. doi: 10.1016/j.cmet.2018.12.001. No abstract available.

3.

Mitochondrial complex III is essential for suppressive function of regulatory T cells.

Weinberg SE, Singer BD, Steinert EM, Martinez CA, Mehta MM, Martínez-Reyes I, Gao P, Helmin KA, Abdala-Valencia H, Sena LA, Schumacker PT, Turka LA, Chandel NS.

Nature. 2019 Jan;565(7740):495-499. doi: 10.1038/s41586-018-0846-z. Epub 2019 Jan 9.

4.

Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis.

Reyfman PA, Walter JM, Joshi N, Anekalla KR, McQuattie-Pimentel AC, Chiu S, Fernandez R, Akbarpour M, Chen CI, Ren Z, Verma R, Abdala-Valencia H, Nam K, Chi M, Han S, Gonzalez-Gonzalez FJ, Soberanes S, Watanabe S, Williams KJN, Flozak AS, Nicholson TT, Morgan VK, Winter DR, Hinchcliff M, Hrusch CL, Guzy RD, Bonham CA, Sperling AI, Bag R, Hamanaka RB, Mutlu GM, Yeldandi AV, Marshall SA, Shilatifard A, Amaral LAN, Perlman H, Sznajder JI, Argento AC, Gillespie CT, Dematte J, Jain M, Singer BD, Ridge KM, Lam AP, Bharat A, Bhorade SM, Gottardi CJ, Budinger GRS, Misharin AV.

Am J Respir Crit Care Med. 2019 Jun 15;199(12):1517-1536. doi: 10.1164/rccm.201712-2410OC.

5.

Inflammatory pathways are upregulated in the nasal epithelium in patients with idiopathic pulmonary fibrosis.

Sala MA, Balderas-Martínez YI, Buendía-Roldan I, Abdala-Valencia H, Nam K, Jain M, Bhorade S, Bharat A, Reyfman PA, Ridge KM, Pardo A, Sznajder JI, Budinger GRS, Misharin AV, Selman M.

Respir Res. 2018 Nov 26;19(1):233. doi: 10.1186/s12931-018-0932-7.

6.

Multidimensional Assessment of the Host Response in Mechanically Ventilated Patients with Suspected Pneumonia.

Walter JM, Ren Z, Yacoub T, Reyfman PA, Shah RD, Abdala-Valencia H, Nam K, Morgan VK, Anekalla KR, Joshi N, McQuattie-Pimentel AC, Chen CI, Chi M, Han S, Gonzalez-Gonzalez FJ, Soberanes S, Aillon RP, Watanabe S, Williams KJN, Lu Z, Paonessa J, Hountras P, Breganio M, Borkowski N, Donnelly HK, Allen JP, Amaral LA, Bharat A, Misharin AV, Bagheri N, Hauser AR, Budinger GRS, Wunderink RG.

Am J Respir Crit Care Med. 2019 May 15;199(10):1225-1237. doi: 10.1164/rccm.201804-0650OC.

PMID:
30398927
7.

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis.

Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Reyfman PA, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, Abdala-Valencia H, Chiarella SE, Sun KA, Woods PS, Ghio AJ, Jain M, Perlman H, Ridge KM, Morimoto RI, Sznajder JI, Balch WE, Bhorade SM, Bharat A, Prakriya M, Chandel NS, Mutlu GM, Budinger GRS.

Cell Metab. 2019 Feb 5;29(2):335-347.e5. doi: 10.1016/j.cmet.2018.09.019. Epub 2018 Oct 11. Erratum in: Cell Metab. 2019 Feb 5;29(2):503.

PMID:
30318339
8.

Multidimensional assessment of alveolar T cells in critically ill patients.

Walter JM, Helmin KA, Abdala-Valencia H, Wunderink RG, Singer BD.

JCI Insight. 2018 Sep 6;3(17). pii: 123287. doi: 10.1172/jci.insight.123287. eCollection 2018 Sep 6.

9.

VCAM-1 induces signals that stimulate ZO-1 serine phosphorylation and reduces ZO-1 localization at lung endothelial cell junctions.

Abdala-Valencia H, Kountz TS, Marchese ME, Cook-Mills JM.

J Leukoc Biol. 2018 Jul;104(1):215-228. doi: 10.1002/JLB.2MA1117-427RR. Epub 2018 Jun 11.

10.

DNA methylation regulates the neonatal CD4+ T-cell response to pneumonia in mice.

McGrath-Morrow SA, Ndeh R, Helmin KA, Chen SY, Anekalla KR, Abdala-Valencia H, D'Alessio FR, Collaco JM, Singer BD.

J Biol Chem. 2018 Jul 27;293(30):11772-11783. doi: 10.1074/jbc.RA118.003589. Epub 2018 Jun 4.

11.

Matrix protein tenascin-C expands and reversibly blocks maturation of murine eosinophil progenitors.

Doan TC, Jeong BM, Coden ME, Loffredo LF, Bhattacharyya S, Chiarella SE, Varga J, Abdala-Valencia H, Berdnikovs S.

J Allergy Clin Immunol. 2018 Aug;142(2):695-698.e4. doi: 10.1016/j.jaci.2018.02.054. Epub 2018 Apr 27. No abstract available.

12.

Shaping eosinophil identity in the tissue contexts of development, homeostasis, and disease.

Abdala-Valencia H, Coden ME, Chiarella SE, Jacobsen EA, Bochner BS, Lee JJ, Berdnikovs S.

J Leukoc Biol. 2018 Jul;104(1):95-108. doi: 10.1002/JLB.1MR1117-442RR. Epub 2018 Apr 14. Review.

13.

Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis.

Mandelin AM 2nd, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Bridges SL Jr, Bathon JM, Atkinson JP, Fox DA, Matteson EL, Buckley CD, Pitzalis C, Parks D, Hughes LB, Geraldino-Pardilla L, Ike R, Phillips K, Wright K, Filer A, Kelly S, Ruderman EM, Morgan V, Abdala-Valencia H, Misharin AV, Budinger GS, Bartom ET, Pope RM, Perlman H, Winter DR.

Arthritis Rheumatol. 2018 Jun;70(6):841-854. doi: 10.1002/art.40453. Epub 2018 May 3.

14.

Bim suppresses the development of SLE by limiting myeloid inflammatory responses.

Tsai F, Homan PJ, Agrawal H, Misharin AV, Abdala-Valencia H, Haines GK 3rd, Dominguez S, Bloomfield CL, Saber R, Chang A, Mohan C, Hutcheson J, Davidson A, Budinger GRS, Bouillet P, Dorfleutner A, Stehlik C, Winter DR, Cuda CM, Perlman H.

J Exp Med. 2017 Dec 4;214(12):3753-3773. doi: 10.1084/jem.20170479. Epub 2017 Nov 7.

15.

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.

Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen CI, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Gates K, Lam AP, Nicholson TT, Homan PJ, Soberanes S, Dominguez S, Morgan VK, Saber R, Shaffer A, Hinchcliff M, Marshall SA, Bharat A, Berdnikovs S, Bhorade SM, Bartom ET, Morimoto RI, Balch WE, Sznajder JI, Chandel NS, Mutlu GM, Jain M, Gottardi CJ, Singer BD, Ridge KM, Bagheri N, Shilatifard A, Budinger GRS, Perlman H.

J Exp Med. 2017 Aug 7;214(8):2387-2404. doi: 10.1084/jem.20162152. Epub 2017 Jul 10.

16.

Donor pulmonary intravascular nonclassical monocytes recruit recipient neutrophils and mediate primary lung allograft dysfunction.

Zheng Z, Chiu S, Akbarpour M, Sun H, Reyfman PA, Anekalla KR, Abdala-Valencia H, Edgren D, Li W, Kreisel D, Korobova FV, Fernandez R, McQuattie-Pimentel A, Zhang ZJ, Perlman H, Misharin AV, Scott Budinger GR, Bharat A.

Sci Transl Med. 2017 Jun 14;9(394). pii: eaal4508. doi: 10.1126/scitranslmed.aal4508.

17.

Beyond epithelial-to-mesenchymal transition: Common suppression of differentiation programs underlies epithelial barrier dysfunction in mild, moderate, and severe asthma.

Loffredo LF, Abdala-Valencia H, Anekalla KR, Cuervo-Pardo L, Gottardi CJ, Berdnikovs S.

Allergy. 2017 Dec;72(12):1988-2004. doi: 10.1111/all.13222. Epub 2017 Jul 6.

18.

Interaction of vitamin E isoforms on asthma and allergic airway disease.

Cook-Mills J, Gebretsadik T, Abdala-Valencia H, Green J, Larkin EK, Dupont WD, Shu XO, Gross M, Bai C, Gao YT, Hartman TJ, Rosas-Salazar C, Hartert T.

Thorax. 2016 Oct;71(10):954-6. doi: 10.1136/thoraxjnl-2016-208494. Epub 2016 Jun 2.

19.

γ-Tocopherol supplementation of allergic female mice augments development of CD11c+CD11b+ dendritic cells in utero and allergic inflammation in neonates.

Abdala-Valencia H, Soveg F, Cook-Mills JM.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 15;310(8):L759-71. doi: 10.1152/ajplung.00301.2015. Epub 2016 Jan 22.

20.

Phenotypic plasticity and targeting of Siglec-F(high) CD11c(low) eosinophils to the airway in a murine model of asthma.

Abdala Valencia H, Loffredo LF, Misharin AV, Berdnikovs S.

Allergy. 2016 Feb;71(2):267-71. doi: 10.1111/all.12776. Epub 2015 Oct 20.

PMID:
26414117
21.

Regulation of allergic lung inflammation by endothelial cell transglutaminase 2.

Soveg F, Abdala-Valencia H, Campbell J, Morales-Nebreda L, Mutlu GM, Cook-Mills JM.

Am J Physiol Lung Cell Mol Physiol. 2015 Sep 15;309(6):L573-83. doi: 10.1152/ajplung.00199.2015. Epub 2015 Jul 24.

22.

Tetraspanin CD151 Is a Negative Regulator of FcεRI-Mediated Mast Cell Activation.

Abdala-Valencia H, Bryce PJ, Schleimer RP, Wechsler JB, Loffredo LF, Cook-Mills JM, Hsu CL, Berdnikovs S.

J Immunol. 2015 Aug 15;195(4):1377-87. doi: 10.4049/jimmunol.1302874. Epub 2015 Jul 1.

23.

α-Tocopherol supplementation of allergic female mice inhibits development of CD11c+CD11b+ dendritic cells in utero and allergic inflammation in neonates.

Abdala-Valencia H, Berdnikovs S, Soveg FW, Cook-Mills JM.

Am J Physiol Lung Cell Mol Physiol. 2014 Sep 15;307(6):L482-96. doi: 10.1152/ajplung.00132.2014. Epub 2014 Jul 11.

24.

Vitamin E isoforms as modulators of lung inflammation.

Abdala-Valencia H, Berdnikovs S, Cook-Mills JM.

Nutrients. 2013 Oct 31;5(11):4347-63. doi: 10.3390/nu5114347. Review.

25.

Two faces of vitamin E in the lung.

Cook-Mills JM, Abdala-Valencia H, Hartert T.

Am J Respir Crit Care Med. 2013 Aug 1;188(3):279-84. doi: 10.1164/rccm.201303-0503ED. Review.

26.

Endothelial cell PTP1B regulates leukocyte recruitment during allergic inflammation.

Berdnikovs S, Abdala-Valencia H, Cook-Mills JM.

Am J Physiol Lung Cell Mol Physiol. 2013 Feb 15;304(4):L240-9. doi: 10.1152/ajplung.00375.2012. Epub 2012 Dec 28.

27.

Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan.

Abdala-Valencia H, Berdnikovs S, McCary CA, Urick D, Mahadevia R, Marchese ME, Swartz K, Wright L, Mutlu GM, Cook-Mills JM.

Am J Physiol Lung Cell Mol Physiol. 2012 Oct 15;303(8):L642-60. doi: 10.1152/ajplung.00406.2011. Epub 2012 Jul 27.

28.

Vitamin E isoforms differentially regulate intercellular adhesion molecule-1 activation of PKCα in human microvascular endothelial cells.

Abdala-Valencia H, Berdnikovs S, Cook-Mills JM.

PLoS One. 2012;7(7):e41054. doi: 10.1371/journal.pone.0041054. Epub 2012 Jul 17.

29.

PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo.

Berdnikovs S, Pavlov VI, Abdala-Valencia H, McCary CA, Klumpp DJ, Tremblay ML, Cook-Mills JM.

J Immunol. 2012 Jan 15;188(2):874-84. doi: 10.4049/jimmunol.1004108. Epub 2011 Dec 9.

30.

Mechanisms for vascular cell adhesion molecule-1 activation of ERK1/2 during leukocyte transendothelial migration.

Abdala-Valencia H, Berdnikovs S, Cook-Mills JM.

PLoS One. 2011;6(10):e26706. doi: 10.1371/journal.pone.0026706. Epub 2011 Oct 21.

31.

Supplemental and highly elevated tocopherol doses differentially regulate allergic inflammation: reversibility of α-tocopherol and γ-tocopherol's effects.

McCary CA, Abdala-Valencia H, Berdnikovs S, Cook-Mills JM.

J Immunol. 2011 Mar 15;186(6):3674-85. doi: 10.4049/jimmunol.1003037. Epub 2011 Feb 11.

32.

Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants.

Cook-Mills JM, Marchese ME, Abdala-Valencia H.

Antioxid Redox Signal. 2011 Sep 15;15(6):1607-38. doi: 10.1089/ars.2010.3522. Epub 2011 May 11. Review.

33.

Isoforms of vitamin E have opposing immunoregulatory functions during inflammation by regulating leukocyte recruitment.

Berdnikovs S, Abdala-Valencia H, McCary C, Somand M, Cole R, Garcia A, Bryce P, Cook-Mills JM.

J Immunol. 2009 Apr 1;182(7):4395-405. doi: 10.4049/jimmunol.0803659. Erratum in: J Immunol. 2010 Jul 15;185(2):1341.

34.

Allergic pulmonary inflammation promotes the recruitment of circulating tumor cells to the lung.

Taranova AG, Maldonado D 3rd, Vachon CM, Jacobsen EA, Abdala-Valencia H, McGarry MP, Ochkur SI, Protheroe CA, Doyle A, Grant CS, Cook-Mills J, Birnbaumer L, Lee NA, Lee JJ.

Cancer Res. 2008 Oct 15;68(20):8582-9. doi: 10.1158/0008-5472.CAN-08-1673.

35.

Galphai2-mediated signaling events in the endothelium are involved in controlling leukocyte extravasation.

Pero RS, Borchers MT, Spicher K, Ochkur SI, Sikora L, Rao SP, Abdala-Valencia H, O'Neill KR, Shen H, McGarry MP, Lee NA, Cook-Mills JM, Sriramarao P, Simon MI, Birnbaumer L, Lee JJ.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4371-6. Epub 2007 Mar 7.

36.

VCAM-1 activation of endothelial cell protein tyrosine phosphatase 1B.

Deem TL, Abdala-Valencia H, Cook-Mills JM.

J Immunol. 2007 Mar 15;178(6):3865-73.

37.

Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in experimentally induced asthma.

Abdala-Valencia H, Earwood J, Bansal S, Jansen M, Babcock G, Garvy B, Wills-Karp M, Cook-Mills JM.

Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1111-25. Epub 2007 Feb 9.

38.

VCAM-1 signals activate endothelial cell protein kinase Calpha via oxidation.

Abdala-Valencia H, Cook-Mills JM.

J Immunol. 2006 Nov 1;177(9):6379-87.

39.

Antileishmanial activities and mechanisms of action of indole-based azoles.

Pagniez F, Abdala-Valencia H, Marchand P, Le Borgne M, Le Baut G, Robert-Piessard S, Le Pape P.

J Enzyme Inhib Med Chem. 2006 Jun;21(3):277-83.

PMID:
16918075
40.

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