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Items: 16

1.

Amelioration of perivascular adipose inflammation reverses vascular dysfunction in a model of nonobese prediabetic metabolic challenge: potential role of antidiabetic drugs.

Elkhatib MAW, Mroueh A, Rafeh RW, Sleiman F, Fouad H, Saad EI, Fouda MA, Elgaddar O, Issa K, Eid AH, Eid AA, Abd-Elrahman KS, El-Yazbi AF.

Transl Res. 2019 Jul 29. pii: S1931-5244(19)30144-6. doi: 10.1016/j.trsl.2019.07.009. [Epub ahead of print]

PMID:
31408626
2.

Structural determinants governing ╬▓-arrestin2 interaction with PDZ proteins and recruitment to CRFR1.

Gupta S, Abd-Elrahman KS, Albaker A, Dunn HA, Ferguson SSG.

Cell Signal. 2019 Jul 22;63:109361. doi: 10.1016/j.cellsig.2019.109361. [Epub ahead of print]

PMID:
31344440
3.

Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington's pathology in zQ175 mice.

Abd-Elrahman KS, Ferguson SSG.

Mol Brain. 2019 Apr 8;12(1):35. doi: 10.1186/s13041-019-0456-1.

4.

Podocyte NADPH Oxidase 5 Promotes Renal Inflammation Regulated by the Toll-Like Receptor Pathway.

Holterman CE, Boisvert NC, Thibodeau JF, Kamto E, Novakovic M, Abd-Elrahman KS, Ferguson SSG, Kennedy CRJ.

Antioxid Redox Signal. 2019 May 20;30(15):1817-1830. doi: 10.1089/ars.2017.7402. Epub 2018 Sep 8.

PMID:
30070142
5.

GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation.

Tutunea-Fatan E, Abd-Elrahman KS, Thibodeau JF, Holterman CE, Holleran BJ, Leduc R, Kennedy CRJ, Gros R, Ferguson SSG.

Sci Rep. 2018 Jul 30;8(1):11415. doi: 10.1038/s41598-018-29876-8.

6.

Autophagy is increased following either pharmacological or genetic silencing of mGluR5 signaling in Alzheimer's disease mouse models.

Abd-Elrahman KS, Hamilton A, Vasefi M, Ferguson SSG.

Mol Brain. 2018 Apr 10;11(1):19. doi: 10.1186/s13041-018-0364-9.

7.

mGluR5 antagonism increases autophagy and prevents disease progression in the zQ175 mouse model of Huntington's disease.

Abd-Elrahman KS, Hamilton A, Hutchinson SR, Liu F, Russell RC, Ferguson SSG.

Sci Signal. 2017 Dec 19;10(510). pii: eaan6387. doi: 10.1126/scisignal.aan6387.

PMID:
29259100
8.

ROK and Arteriolar Myogenic Tone Generation: Molecular Evidence in Health and Disease.

El-Yazbi AF, Abd-Elrahman KS.

Front Pharmacol. 2017 Feb 23;8:87. doi: 10.3389/fphar.2017.00087. eCollection 2017. Review.

9.

Vascular Smooth Muscle-Specific EP4 Receptor Deletion in Mice Exacerbates Angiotensin II-Induced Renal Injury.

Thibodeau JF, Holterman CE, He Y, Carter A, Cron GO, Boisvert NC, Abd-Elrahman KS, Hsu KJ, Ferguson SS, Kennedy CR.

Antioxid Redox Signal. 2016 Oct 20;25(12):642-656. Epub 2016 Aug 5.

PMID:
27245461
10.

Abnormal myosin phosphatase targeting subunit 1 phosphorylation and actin polymerization contribute to impaired myogenic regulation of cerebral arterial diameter in the type 2 diabetic Goto-Kakizaki rat.

Abd-Elrahman KS, Colinas O, Walsh EJ, Zhu HL, Campbell CM, Walsh MP, Cole WC.

J Cereb Blood Flow Metab. 2017 Jan;37(1):227-240. Epub 2015 Dec 31.

11.

PKC-mediated cerebral vasoconstriction: Role of myosin light chain phosphorylation versus actin cytoskeleton reorganization.

El-Yazbi AF, Abd-Elrahman KS, Moreno-Dominguez A.

Biochem Pharmacol. 2015 Jun 15;95(4):263-78. doi: 10.1016/j.bcp.2015.04.011. Epub 2015 Apr 27.

PMID:
25931148
12.

Abnormal Rho-associated kinase activity contributes to the dysfunctional myogenic response of cerebral arteries in type 2 diabetes.

Abd-Elrahman KS, Walsh MP, Cole WC.

Can J Physiol Pharmacol. 2015 Mar;93(3):177-84. doi: 10.1139/cjpp-2014-0437. Epub 2015 Jan 12. Review.

PMID:
25660561
13.

PPAR╬│ dependence of cyclosporine-isoprenaline renovascular interaction: roles of nitric oxide synthase and heme oxygenase.

El-Gowelli HM, Abd-Elrahman KS, Saad EI, El-Gowilly SM, Abdel-Galil AG, El-Mas MM.

J Cardiovasc Pharmacol. 2011 Aug;58(2):173-80. doi: 10.1097/FJC.0b013e31821ed803.

PMID:
21558877
14.

Pioglitazone abrogates cyclosporine-evoked hypertension via rectifying abnormalities in vascular endothelial function.

El-Mas MM, El-Gowelli HM, Abd-Elrahman KS, Saad EI, Abdel-Galil AG, Abdel-Rahman AA.

Biochem Pharmacol. 2011 Feb 15;81(4):526-33. doi: 10.1016/j.bcp.2010.11.013. Epub 2010 Nov 27.

15.

Stromatoxin-sensitive, heteromultimeric Kv2.1/Kv9.3 channels contribute to myogenic control of cerebral arterial diameter.

Zhong XZ, Abd-Elrahman KS, Liao CH, El-Yazbi AF, Walsh EJ, Walsh MP, Cole WC.

J Physiol. 2010 Nov 15;588(Pt 22):4519-37. doi: 10.1113/jphysiol.2010.196618. Epub 2010 Sep 27.

16.

Role of PPAR gamma/nitric oxide synthase signaling in the cyclosporine-induced attenuation of endothelium-dependent renovascular vasodilation.

Abd-Elrahman KS, El-Gowelli HM, Saad EI, Abdel-Galil AG, El-Mas MM.

J Cardiovasc Pharmacol. 2010 Aug;56(2):195-202. doi: 10.1097/FJC.0b013e3181e74d83.

PMID:
20505521

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