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Items: 1 to 20 of 149

1.

Essential role of STAT-3 dependent NF-κB activation on IL-6-mediated downregulation of hepatic transporters.

Abualsunun WA, Sahin C, Cummins CL, Piquette-Miller M.

Eur J Pharm Sci. 2019 Nov 15:105151. doi: 10.1016/j.ejps.2019.105151. [Epub ahead of print]

PMID:
31740392
2.

Estradiol regulation of P-glycoprotein expression in mouse kidney and human tubular epithelial cells, implication for renal clearance of drugs.

Kanado Y, Tsurudome Y, Omata Y, Yasukochi S, Kusunose N, Akamine T, Matsunaga N, Koyanagi S, Ohdo S.

Biochem Biophys Res Commun. 2019 Nov 12;519(3):613-619. doi: 10.1016/j.bbrc.2019.09.021. Epub 2019 Sep 17.

PMID:
31540689
3.

Dysregulation of placental ABC transporters in a murine model of malaria-induced preterm labor.

Fontes KN, Reginatto MW, Silva NL, Andrade CBV, Bloise FF, Monteiro VRS, Silva-Filho JL, Imperio GE, Pimentel-Coelho PM, Pinheiro AAS, Matthews SG, Bloise E, Ortiga-Carvalho TM.

Sci Rep. 2019 Aug 7;9(1):11488. doi: 10.1038/s41598-019-47865-3.

4.

HgS and Zuotai differ from HgCl2 and methyl mercury in intestinal Hg absorption, transporter expression and gut microbiome in mice.

Zhang BB, Liu YM, Hu AL, Xu SF, Fan LD, Cheng ML, Li C, Wei LX, Liu J.

Toxicol Appl Pharmacol. 2019 Sep 15;379:114615. doi: 10.1016/j.taap.2019.114615. Epub 2019 Jun 6.

PMID:
31175882
5.

Diet-induced obese alters the expression and function of hepatic drug-metabolizing enzymes and transporters in rats.

Zhang L, Xu P, Cheng Y, Wang P, Ma X, Liu M, Wang X, Xu F.

Biochem Pharmacol. 2019 Jun;164:368-376. doi: 10.1016/j.bcp.2019.05.002. Epub 2019 May 4.

PMID:
31063713
6.

Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide.

Koehn LM, Dziegielewska KM, Møllgård K, Saudrais E, Strazielle N, Ghersi-Egea JF, Saunders NR, Habgood MD.

Sci Rep. 2019 Apr 12;9(1):5998. doi: 10.1038/s41598-019-42402-8.

7.
8.

Fenofibrate Decreases Hepatic P-Glycoprotein in a Rat Model of Hereditary Hypertriglyceridemia.

Poruba M, Matuskova Z, Hüttl M, Malinska H, Oliyarnyk O, Markova I, Gurska S, Kazdova L, Vecera R.

Front Pharmacol. 2019 Feb 7;10:56. doi: 10.3389/fphar.2019.00056. eCollection 2019.

9.

Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissues.

Ibold B, Faust I, Tiemann J, Gorgels TGMF, Bergen AAB, Knabbe C, Hendig D.

Lipids Health Dis. 2019 Jan 5;18(1):2. doi: 10.1186/s12944-018-0943-x.

10.

ABCB1 (P-glycoprotein) regulates vitamin D absorption and contributes to its transintestinal efflux.

Margier M, Collet X, le May C, Desmarchelier C, André F, Lebrun C, Defoort C, Bluteau A, Borel P, Lespine A, Reboul E.

FASEB J. 2019 Feb;33(2):2084-2094. doi: 10.1096/fj.201800956R. Epub 2018 Sep 17.

PMID:
30222077
11.

The effect of saikosaponin D on doxorubicin pharmacokinetics and its MDR reversal in MCF-7/adr cell xenografts.

Li C, Xue HG, Feng LJ, Wang ML, Wang P, Gai XD.

Eur Rev Med Pharmacol Sci. 2017 Oct;21(19):4437-4445.

12.

The impact of P-glycoprotein and breast cancer resistance protein on the brain pharmacokinetics and pharmacodynamics of a panel of MEK inhibitors.

de Gooijer MC, Zhang P, Weijer R, Buil LCM, Beijnen JH, van Tellingen O.

Int J Cancer. 2018 Jan 15;142(2):381-391. doi: 10.1002/ijc.31052. Epub 2017 Oct 4.

13.

Abcb1a and Abcb1b genes function differentially in blood-testis barrier dynamics in the rat.

Su L, Cheng YC, Lee WM, Zhang M, Yang F, Zhao B, Han D, Liu Y, Hu D.

Cell Death Dis. 2017 Sep 7;8(9):e3038. doi: 10.1038/cddis.2017.435.

14.
15.

L1210 Cells Overexpressing ABCB1 Drug Transporters Are Resistant to Inhibitors of the N- and O-glycosylation of Proteins.

Pavlikova L, Seres M, Hano M, Bohacova V, Sevcikova I, Kyca T, Breier A, Sulova Z.

Molecules. 2017 Jul 3;22(7). pii: E1104. doi: 10.3390/molecules22071104.

16.

Genetic background influences susceptibility to chemotherapy-induced hematotoxicity.

Gatti DM, Weber SN, Goodwin NC, Lammert F, Churchill GA.

Pharmacogenomics J. 2018 Apr;18(2):319-330. doi: 10.1038/tpj.2017.23. Epub 2017 Jun 13.

17.

Spatiotemporal Changes in P-glycoprotein Levels in Brain and Peripheral Tissues Following Ischemic Stroke in Rats.

DeMars KM, Yang C, Hawkins KE, McCrea AO, Siwarski DM, Candelario-Jalil E.

J Exp Neurosci. 2017 Apr 7;11:1179069517701741. doi: 10.1177/1179069517701741. eCollection 2017.

18.

Impact of endotoxin on the expression of drug transporters in the placenta of HIV-1 transgenic (HIV-Tg) rats.

Ghoneim RH, Kojovic D, Piquette-Miller M.

Eur J Pharm Sci. 2017 May 1;102:94-102. doi: 10.1016/j.ejps.2017.03.004. Epub 2017 Mar 6.

PMID:
28274777
19.

Lack of P-glycoprotein Results in Impairment of Removal of Beta-Amyloid and Increased Intraparenchymal Cerebral Amyloid Angiopathy after Active Immunization in a Transgenic Mouse Model of Alzheimer's Disease.

Bruckmann S, Brenn A, Grube M, Niedrig K, Holtfreter S, von Bohlen und Halbach O, Groschup M, Keller M, Vogelgesang S.

Curr Alzheimer Res. 2017;14(6):656-667. doi: 10.2174/1567205013666161201201227.

PMID:
27915995
20.

Cooperativity between verapamil and ATP bound to the efflux transporter P-glycoprotein.

Ledwitch KV, Gibbs ME, Barnes RW, Roberts AG.

Biochem Pharmacol. 2016 Oct 15;118:96-108. doi: 10.1016/j.bcp.2016.08.013. Epub 2016 Aug 13.

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