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Items: 1 to 50 of 100

1.

Ticagrelor versus placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: Rationale and design of a randomized, double-blind, parallel-group, multicenter phase 3 study (HESTIA3).

Heeney MM, Abboud MR, Amilon C, Andersson M, Githanga J, Inusa B, Kanter J, Leonsson-Zachrisson M, Michelson AD, Berggren AR; HESTIA3 study investigators.

Contemp Clin Trials. 2019 Aug 22:105835. doi: 10.1016/j.cct.2019.105835. [Epub ahead of print]

2.

A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease.

Vichinsky E, Hoppe CC, Ataga KI, Ware RE, Nduba V, El-Beshlawy A, Hassab H, Achebe MM, Alkindi S, Brown RC, Diuguid DL, Telfer P, Tsitsikas DA, Elghandour A, Gordeuk VR, Kanter J, Abboud MR, Lehrer-Graiwer J, Tonda M, Intondi A, Tong B, Howard J; HOPE Trial Investigators.

N Engl J Med. 2019 Aug 8;381(6):509-519. doi: 10.1056/NEJMoa1903212. Epub 2019 Jun 14.

PMID:
31199090
3.

Clinical Prognostic Factors and Outcome in Pediatric Osteosarcoma: Effect of Delay in Local Control and Degree of Necrosis in a Multidisciplinary Setting in Lebanon.

Abou Ali B, Salman M, Ghanem KM, Boulos F, Haidar R, Saghieh S, Akel S, Muwakkit SA, El-Solh H, Saab R, Tamim H, Abboud MR.

J Glob Oncol. 2019 Apr;5:1-8. doi: 10.1200/JGO.17.00241.

4.

Isolated delayed metastasis to the talus from Ewing's sarcoma.

Nasr L, Naffaa L, El Alayli A, Abboud MR, Khoury NJ.

J Radiol Case Rep. 2018 Aug 31;12(8):17-24. doi: 10.3941/jrcr.v12i8.3164. eCollection 2018 Aug.

5.

Ticagrelor does not impact patient-reported pain in young adults with sickle cell disease: a multicentre, randomised phase IIb study.

Kanter J, Abboud MR, Kaya B, Nduba V, Amilon C, Gottfridsson C, Rensfeldt M, Leonsson-Zachrisson M; HESTIA2 study investigators.

Br J Haematol. 2019 Jan;184(2):269-278. doi: 10.1111/bjh.15646. Epub 2018 Nov 16.

6.

Genetic polymorphisms in candidate genes are not associated with increased vincristine-related peripheral neuropathy in Arab children treated for acute childhood leukemia: a single institution study.

Zgheib NK, Ghanem KM, Tamim H, Aridi C, Shahine R, Tarek N, Saab R, Abboud MR, El-Solh H, Muwakkit SA.

Pharmacogenet Genomics. 2018 Aug;28(8):189-195. doi: 10.1097/FPC.0000000000000345.

PMID:
30119132
7.

Fludarabine-based reduced intensity regimen for matched related donor hematopoietic stem cell transplantation in acquired severe aplastic anemia.

Ghanem KM, Kharfan-Dabaja MA, El-Solh H, Harris N, Kreidieh N, Nehme R, Muwakkit SA, Saab R, Bazarbachi A, Abboud MR.

Curr Res Transl Med. 2017 Sep;65(3):115-119. doi: 10.1016/j.retram.2017.09.001. Epub 2017 Oct 4.

PMID:
28988743
8.

Renal Medullary Carcinoma: Establishing Standards in Practice.

Beckermann KE, Sharma D, Chaturvedi S, Msaouel P, Abboud MR, Allory Y, Bourdeaut F, Calderaro J, de Cubas AA, Derebail VK, Hong AL, Naik RP, Malouf GG, Mullen EA, Reuter VE, Roberts CWM, Walker CL, Wood CG, DeBaun MR, Van Poppel H, Tannir NM, Rathmell WK.

J Oncol Pract. 2017 Jul;13(7):414-421. doi: 10.1200/JOP.2017.020909. Review.

9.

Cerebral sinus venous thrombosis during childhood acute lymphoblastic leukemia therapy: Risk factors and management.

Ghanem KM, Dhayni RM, Al-Aridi C, Tarek N, Tamim H, Chan AKC, Saab R, Abboud MR, El-Solh H, Muwakkit SA.

Pediatr Blood Cancer. 2017 Dec;64(12). doi: 10.1002/pbc.26694. Epub 2017 Jun 29.

PMID:
28660695
10.

Interventions for preventing silent cerebral infarcts in people with sickle cell disease.

Estcourt LJ, Fortin PM, Hopewell S, Trivella M, Doree C, Abboud MR.

Cochrane Database Syst Rev. 2017 May 13;5:CD012389. doi: 10.1002/14651858.CD012389.pub2. Review.

11.

Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.

Witzel M, Petersheim D, Fan Y, Bahrami E, Racek T, Rohlfs M, Puchałka J, Mertes C, Gagneur J, Ziegenhain C, Enard W, Stray-Pedersen A, Arkwright PD, Abboud MR, Pazhakh V, Lieschke GJ, Krawitz PM, Dahlhoff M, Schneider MR, Wolf E, Horny HP, Schmidt H, Schäffer AA, Klein C.

Nat Genet. 2017 May;49(5):742-752. doi: 10.1038/ng.3833. Epub 2017 Apr 3.

12.

Interventions for preventing silent cerebral infarcts in people with sickle cell disease.

Estcourt LJ, Fortin PM, Hopewell S, Trivella M, Doree C, Abboud MR.

Cochrane Database Syst Rev. 2016 Oct;2016(10). pii: CD012389. doi: 10.1002/14651858.CD012389. Update in: Cochrane Database Syst Rev. 2017 May 13;5:CD012389.

13.

Sickle cell disease.

Ware RE, de Montalembert M, Tshilolo L, Abboud MR.

Lancet. 2017 Jul 15;390(10091):311-323. doi: 10.1016/S0140-6736(17)30193-9. Epub 2017 Feb 1. Review.

PMID:
28159390
14.

NUDT15 and TPMT genetic polymorphisms are related to 6-mercaptopurine intolerance in children treated for acute lymphoblastic leukemia at the Children's Cancer Center of Lebanon.

Zgheib NK, Akika R, Mahfouz R, Aridi CA, Ghanem KM, Saab R, Abboud MR, Tarek N, El Solh H, Muwakkit SA.

Pediatr Blood Cancer. 2017 Jan;64(1):146-150. doi: 10.1002/pbc.26189. Epub 2016 Aug 31.

PMID:
27577869
15.

Collaborative Pediatric Bone Tumor Program to Improve Access to Specialized Care: An Initiative by the Lebanese Children's Oncology Group.

Saab R, Merabi Z, Abboud MR, Muwakkit S, Noun P, Gemayel G, Bechara E, Khalifeh H, Farah R, Kabbara N, El-Khoury T, Al-Yousef R, Haidar R, Saghieh S, Eid T, Akel S, Khoury N, Bayram L, Krasin MJ, Jeha S, El-Solh H.

J Glob Oncol. 2016 May 18;3(1):23-30. doi: 10.1200/JGO.2016.003103. eCollection 2017 Feb.

16.

A Multinational Trial of Prasugrel for Sickle Cell Vaso-Occlusive Events.

Heeney MM, Hoppe CC, Abboud MR, Inusa B, Kanter J, Ogutu B, Brown PB, Heath LE, Jakubowski JA, Zhou C, Zamoryakhin D, Agbenyega T, Colombatti R, Hassab HM, Nduba VN, Oyieko JN, Robitaille N, Segbefia CI, Rees DC; DOVE Investigators.

N Engl J Med. 2016 Feb 18;374(7):625-35. doi: 10.1056/NEJMoa1512021. Epub 2015 Dec 8.

17.

Effect of Malnutrition at Diagnosis on Clinical Outcomes of Children With Acute Lymphoblastic Leukemia.

Yazbeck N, Samia L, Saab R, Abboud MR, Solh H, Muwakkit S.

J Pediatr Hematol Oncol. 2016 Mar;38(2):107-10. doi: 10.1097/MPH.0000000000000428.

PMID:
26479995
18.

13-valent pneumococcal conjugate vaccine (PCV13) is immunogenic and safe in children 6-17 years of age with sickle cell disease previously vaccinated with 23-valent pneumococcal polysaccharide vaccine (PPSV23): Results of a phase 3 study.

De Montalembert M, Abboud MR, Fiquet A, Inati A, Lebensburger JD, Kaddah N, Mokhtar G, Piga A, Halasa N, Inusa B, Rees DC, Heath PT, Telfer P, Driscoll C, Al Hajjar S, Tozzi A, Jiang Q, Emini EA, Gruber WC, Gurtman A, Scott DA.

Pediatr Blood Cancer. 2015 Aug;62(8):1427-36. doi: 10.1002/pbc.25502. Epub 2015 Mar 23. Erratum in: Pediatr Blood Cancer. 2019 Feb;66(2):e27554.

PMID:
25810327
19.

Alpha thalassemia allelic frequency in Lebanon.

Farra C, Badra R, Fares F, Muwakkit S, Dbaibo G, Dabbous I, Ashkar H, Mounsef C, Abboud MR.

Pediatr Blood Cancer. 2015 Jan;62(1):120-2. doi: 10.1002/pbc.25242. Epub 2014 Oct 4.

PMID:
25284125
20.

Priapism, an emerging complication in β-thalassemia intermedia patients.

Mallat NS, Wehbe D, Haddad A, Cappellini MD, Marcon A, Koussa S, Abboud MR, Radwan A, Taher AT.

Hemoglobin. 2014;38(5):351-4. doi: 10.3109/03630269.2014.960087.

PMID:
25271993
21.

Acute lymphoblastic leukemia in low and middle-income countries: disease characteristics and treatment results.

Abboud MR, Ghanem K, Muwakkit S.

Curr Opin Oncol. 2014 Nov;26(6):650-5. doi: 10.1097/CCO.0000000000000125. Review.

PMID:
25202926
22.

Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia.

Zgheib NK, Akra-Ismail M, Aridi C, Mahfouz R, Abboud MR, Solh H, Muwakkit SA.

Pharmacogenet Genomics. 2014 Aug;24(8):387-96. doi: 10.1097/FPC.0000000000000069.

PMID:
25007187
23.

A double-blind, placebo-controlled phase II study of the efficacy and safety of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease.

Reid ME, El Beshlawy A, Inati A, Kutlar A, Abboud MR, Haynes J Jr, Ward R, Sharon B, Taher AT, Smith W, Manwani D, Ghalie RG.

Am J Hematol. 2014 Jul;89(7):709-13. doi: 10.1002/ajh.23725. Epub 2014 Apr 15.

24.

Gene therapy for Wiskott-Aldrich syndrome--long-term efficacy and genotoxicity.

Braun CJ, Boztug K, Paruzynski A, Witzel M, Schwarzer A, Rothe M, Modlich U, Beier R, Göhring G, Steinemann D, Fronza R, Ball CR, Haemmerle R, Naundorf S, Kühlcke K, Rose M, Fraser C, Mathias L, Ferrari R, Abboud MR, Al-Herz W, Kondratenko I, Maródi L, Glimm H, Schlegelberger B, Schambach A, Albert MH, Schmidt M, von Kalle C, Klein C.

Sci Transl Med. 2014 Mar 12;6(227):227ra33. doi: 10.1126/scitranslmed.3007280.

25.

Quality of palliative care in children with cancer in Lebanon.

Abu-Saad Huijer H, Sagherian K, Tamim H, Naifeh Khoury M, Abboud MR.

J Med Liban. 2013 Oct-Dec;61(4):228-36.

PMID:
24428078
26.

A dose-escalation phase IIa study of 2,2-dimethylbutyrate (HQK-1001), an oral fetal globin inducer, in sickle cell disease.

Kutlar A, Reid ME, Inati A, Taher AT, Abboud MR, El-Beshlawy A, Buchanan GR, Smith H, Ataga KI, Perrine SP, Ghalie RG.

Am J Hematol. 2013 Nov;88(11):E255-60. doi: 10.1002/ajh.23533. Epub 2013 Oct 3.

27.

Intracranial blood flow velocities in patients with sickle cell disease and β-thalassemia intermedia.

Abboud MR, Maakaron JE, Khoury RA, Tamim HM, Shehab M, Haddad F, Adams RJ, Taher AT.

Am J Hematol. 2013 Sep;88(9):825. doi: 10.1002/ajh.23496. No abstract available.

28.

Complete heart block in a patient with acute lymphoblastic leukaemia: teicoplanin as a possible cause and review of literature.

Sharif-Yakan A, Arabi M, Musharrafieh UM, Bitar FF, Saab R, Abboud MR, Muwakkit S.

J Clin Pharm Ther. 2013 Apr;38(2):156-8. doi: 10.1111/jcpt.12002. Epub 2012 Dec 28.

PMID:
23278346
29.

Delayed initiation of front-line imatinib therapy predicts for poor response to nilotinib as second-line treatment of imatinib-resistant or intolerant CML: single center report of the ENACT trial in Lebanon.

Otrock ZK, Mahfouz RA, Fahed Z, Farhat FS, Ziade A, Nasr F, Kassem N, Abboud MR.

Int J Hematol. 2012 Oct;96(4):521-4. doi: 10.1007/s12185-012-1168-9. Epub 2012 Sep 9. No abstract available.

PMID:
22961257
30.

Implementation of an intensive risk-stratified treatment protocol for children and adolescents with acute lymphoblastic leukemia in Lebanon.

Muwakkit S, Al-Aridi C, Samra A, Saab R, Mahfouz RA, Farra C, Jeha S, Abboud MR.

Am J Hematol. 2012 Jul;87(7):678-83. doi: 10.1002/ajh.23222. Epub 2012 May 6.

31.

Correlation of non-mass-like abnormal MR signal intensity with pathological findings surrounding pediatric osteosarcoma and Ewing's sarcoma.

Masrouha KZ, Musallam KM, Samra AB, Tawil A, Haidar R, Chakhachiro Z, Saghieh S, Abdallah A, Saab R, Muwakkit S, Abboud MR, Khoury NJ.

Skeletal Radiol. 2012 Nov;41(11):1453-61. Epub 2012 Mar 10.

PMID:
22406919
32.

Pulmonary complications of sickle cell disease.

Khoury RA, Musallam KM, Mroueh S, Abboud MR.

Hemoglobin. 2011;35(5-6):625-35. doi: 10.3109/03630269.2011.621149. Epub 2011 Oct 5. Review.

PMID:
21973051
33.

Cerebral infarction in children with sickle cell disease: a concise overview.

Musallam KM, Khoury RA, Abboud MR.

Hemoglobin. 2011;35(5-6):618-24. doi: 10.3109/03630269.2011.621148. Epub 2011 Oct 3. Review.

PMID:
21967673
34.

Thrombosis in children with acute lymphoblastic leukemia treated at a tertiary care center in Lebanon: revisiting the role of predictive models.

Al-Aridi C, Abboud MR, Saab R, Eid D, Jeha S, Chan AK, Muwakkit SA.

Pediatr Hematol Oncol. 2011 Nov;28(8):676-81. doi: 10.3109/08880018.2011.578705. Epub 2011 Jul 25.

PMID:
21787123
35.

Effect of chronic transfusion therapy on progression of neurovascular pathology in pediatric patients with sickle cell anemia.

Bishop S, Matheus MG, Abboud MR, Cane ID, Adams RJ, Jackson SM, Kalpatthi R.

Blood Cells Mol Dis. 2011 Aug 15;47(2):125-8. doi: 10.1016/j.bcmd.2011.06.002. Epub 2011 Jul 2.

PMID:
21724428
36.

Stem-cell transplantation in children and adults with sickle cell disease: an update.

Khoury R, Abboud MR.

Expert Rev Hematol. 2011 Jun;4(3):343-51. doi: 10.1586/ehm.11.23. Review.

PMID:
21668398
37.

Discontinuing prophylactic transfusions increases the risk of silent brain infarction in children with sickle cell disease: data from STOP II.

Abboud MR, Yim E, Musallam KM, Adams RJ; STOP II Study Investigators.

Blood. 2011 Jul 28;118(4):894-8. doi: 10.1182/blood-2010-12-326298. Epub 2011 Jun 1.

38.

Bereaved parental evaluation of the quality of a palliative care program in Lebanon.

Saad R, Huijer HA, Noureddine S, Muwakkit S, Saab R, Abboud MR.

Pediatr Blood Cancer. 2011 Aug;57(2):310-6. doi: 10.1002/pbc.23082. Epub 2011 Mar 10.

PMID:
21394892
39.

Safety and efficacy of high dose intravenous desferrioxamine for reduction of iron overload in sickle cell disease.

Kalpatthi R, Peters B, Kane I, Holloman D, Rackoff E, Disco D, Jackson S, Laver JH, Abboud MR.

Pediatr Blood Cancer. 2010 Dec 15;55(7):1338-42. doi: 10.1002/pbc.22660.

PMID:
20981690
40.

Seven-year experience of using Repiphysis expandable prosthesis in children with bone tumors.

Saghieh S, Abboud MR, Muwakkit SA, Saab R, Rao B, Haidar R.

Pediatr Blood Cancer. 2010 Sep;55(3):457-63. doi: 10.1002/pbc.22598.

PMID:
20658617
41.

L-asparaginase-induced pancreatitis in children with acute lymphoblastic leukemia: is allopurinol protective?

Muwakkit S, Saab R, Yazbeck N, Samia L, Abboud MR.

Pediatr Hematol Oncol. 2010 Sep;27(6):496-501. doi: 10.3109/08880018.2010.489935. No abstract available.

PMID:
20578808
42.

Severe cerebral vaso-occlusive disease in macrophage activation syndrome.

El-Bitar MK, Muwakkit SA, Hourani R, Abboud MR, Saab R, Dabbagh O.

Pediatr Neurol. 2010 Apr;42(4):283-6. doi: 10.1016/j.pediatrneurol.2009.11.007.

PMID:
20304334
43.

Morvan syndrome following B-cell lymphoma.

El-Bitar MK, Muwakkit SA, Abboud MR, Sawaya RA, Boustany RM.

J Child Neurol. 2010 Aug;25(8):1038-41. doi: 10.1177/0883073809356108. Epub 2010 Jan 28.

PMID:
20110220
44.

Endobronchial metastasis of osteosarcoma presenting as position-dependent and variable airway obstruction of the trachea.

Mazboudi O, Abboud MR, Muwakkit S, Akel S, Husari A.

Thorax. 2010 Jan;65(1):92. doi: 10.1136/thx.2008.112086. No abstract available.

PMID:
20029044
45.

Hematopoietic stem-cell transplantation for adults with sickle cell disease.

Abboud MR.

N Engl J Med. 2009 Dec 10;361(24):2380-1. doi: 10.1056/NEJMe0908574. No abstract available.

PMID:
20007564
46.

Sickle cell disease at the dawn of the molecular era.

Abboud MR, Musallam KM.

Hemoglobin. 2009;33 Suppl 1:S93-S106. doi: 10.3109/03630260903347617. Review.

PMID:
20001639
47.

Pulmonary hypertension in children and young adults with sickle cell disease: evidence for familial clustering.

Dahoui HA, Hayek MN, Nietert PJ, Arabi MT, Muwakkit SA, Saab RH, Bissar AN, Jumaa NM, Farhat FS, Dabbous IA, Bitar FF, Abboud MR.

Pediatr Blood Cancer. 2010 Mar;54(3):398-402. doi: 10.1002/pbc.22306.

PMID:
19827138
48.

Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury.

Adamkiewicz TV, Abboud MR, Paley C, Olivieri N, Kirby-Allen M, Vichinsky E, Casella JF, Alvarez OA, Barredo JC, Lee MT, Iyer RV, Kutlar A, McKie KM, McKie V, Odo N, Gee B, Kwiatkowski JL, Woods GM, Coates T, Wang W, Adams RJ.

Blood. 2009 Nov 19;114(21):4632-8. doi: 10.1182/blood-2009-02-203323. Epub 2009 Aug 31.

49.

Renal venous thrombosis in a newborn with prothrombotic risk factors.

Muwakkit SA, Saab R, Sanjad SA, Bhar SI, Ishak RS, Samad ZA, Chan AK, Abboud MR.

Blood Coagul Fibrinolysis. 2009 Sep;20(6):458-60. doi: 10.1097/MBC.0b013e32832ca3d8.

PMID:
19542880
50.

Venous sinus thrombosis leading to stroke in a patient with sickle cell disease on hydroxyurea and high hemoglobin levels: treatment with thrombolysis.

Sidani CA, Ballourah W, El Dassouki M, Muwakkit S, Dabbous I, Dahoui H, Al-Kutoubi A, Abboud MR.

Am J Hematol. 2008 Oct;83(10):818-20. doi: 10.1002/ajh.21261.

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