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Items: 40

1.

Safety and immunogenicity of a vaccine for extra-intestinal pathogenic Escherichia coli (ESTELLA): a phase 2 randomised controlled trial.

Frenck RW Jr, Ervin J, Chu L, Abbanat D, Spiessens B, Go O, Haazen W, van den Dobbelsteen G, Poolman J, Thoelen S, Ibarra de Palacios P.

Lancet Infect Dis. 2019 Jun;19(6):631-640. doi: 10.1016/S1473-3099(18)30803-X. Epub 2019 May 9.

PMID:
31079947
2.

Safety, tolerability and immunogenicity of the ExPEC4V (JNJ-63871860) vaccine for prevention of invasive extraintestinal pathogenic Escherichia coli disease: A phase 1, randomized, double-blind, placebo-controlled study in healthy Japanese participants.

Inoue M, Ogawa T, Tamura H, Hagiwara Y, Saito Y, Abbanat D, van den Dobbelsteen G, Hermans P, Thoelen S, Poolman J, Ibarra de Palacios P.

Hum Vaccin Immunother. 2018;14(9):2150-2157. doi: 10.1080/21645515.2018.1474316. Epub 2018 Jun 28.

3.

Development and Qualification of an Opsonophagocytic Killing Assay To Assess Immunogenicity of a Bioconjugated Escherichia coli Vaccine.

Abbanat D, Davies TA, Amsler K, He W, Fae K, Janssen S, Poolman JT, van den Dobbelsteen GPJM.

Clin Vaccine Immunol. 2017 Dec 5;24(12). pii: e00123-17. doi: 10.1128/CVI.00123-17. Print 2017 Dec.

4.

Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: a randomised, single-blind, placebo-controlled phase 1b trial.

Huttner A, Hatz C, van den Dobbelsteen G, Abbanat D, Hornacek A, Frölich R, Dreyer AM, Martin P, Davies T, Fae K, van den Nieuwenhof I, Thoelen S, de Vallière S, Kuhn A, Bernasconi E, Viereck V, Kavvadias T, Kling K, Ryu G, Hülder T, Gröger S, Scheiner D, Alaimo C, Harbarth S, Poolman J, Fonck VG.

Lancet Infect Dis. 2017 May;17(5):528-537. doi: 10.1016/S1473-3099(17)30108-1. Epub 2017 Feb 24.

PMID:
28238601
5.

Evaluation of the in vitro activities of ceftobiprole and comparators in staphylococcal colony or microtitre plate biofilm assays.

Abbanat D, Shang W, Amsler K, Santoro C, Baum E, Crespo-Carbone S, Lynch AS.

Int J Antimicrob Agents. 2014 Jan;43(1):32-9. doi: 10.1016/j.ijantimicag.2013.09.013. Epub 2013 Oct 24.

PMID:
24252780
6.

Synergistic activity of ceftobiprole and vancomycin in a rat model of infective endocarditis caused by methicillin-resistant and glycopeptide-intermediate Staphylococcus aureus.

Fernandez J, Abbanat D, Shang W, He W, Amsler K, Hastings J, Queenan AM, Melton JL, Barron AM, Flamm RK, Lynch AS.

Antimicrob Agents Chemother. 2012 Mar;56(3):1476-84. doi: 10.1128/AAC.06057-11. Epub 2012 Jan 9.

7.

Antistaphylococcal activities of the new fluoroquinolone JNJ-Q2.

Morrow BJ, Abbanat D, Baum EZ, Crespo-Carbone SM, Davies TA, He W, Shang W, Queenan AM, Lynch AS.

Antimicrob Agents Chemother. 2011 Dec;55(12):5512-21. doi: 10.1128/AAC.00470-11. Epub 2011 Sep 12.

8.

Comparative effects of carbapenems on bacterial load and host immune response in a Klebsiella pneumoniae murine pneumonia model.

Hilliard JJ, Melton JL, Hall L, Abbanat D, Fernandez J, Ward CK, Bunting RA, Barron A, Lynch AS, Flamm RK.

Antimicrob Agents Chemother. 2011 Feb;55(2):836-44. doi: 10.1128/AAC.00670-10. Epub 2010 Dec 6.

9.

Characterisation of Staphylococcus aureus and Enterococcus faecalis mutants with reduced susceptibility to the investigational oxazolidinone RWJ-416457.

Santoro CM, Bush K, Abbanat D.

Int J Antimicrob Agents. 2010 Nov;36(5):424-9. doi: 10.1016/j.ijantimicag.2010.07.007. Epub 2010 Sep 17.

PMID:
20846828
10.

New antibiotic agents and approaches to treat biofilm-associated infections.

Lynch AS, Abbanat D.

Expert Opin Ther Pat. 2010 Oct;20(10):1373-87. doi: 10.1517/13543776.2010.505923. Review.

PMID:
20636186
11.

In vivo activity of ceftobiprole in murine skin infections due to Staphylococcus aureus and Pseudomonas aeruginosa.

Fernandez J, Hilliard JJ, Abbanat D, Zhang W, Melton JL, Santoro CM, Flamm RK, Bush K.

Antimicrob Agents Chemother. 2010 Jan;54(1):116-25. doi: 10.1128/AAC.00642-09. Epub 2009 Nov 2.

12.

Pharmacokinetic-pharmacodynamic modeling of the in vitro activities of oxazolidinone antimicrobial agents against methicillin-resistant Staphylococcus aureus.

Schmidt S, Sabarinath SN, Barbour A, Abbanat D, Manitpisitkul P, Sha S, Derendorf H.

Antimicrob Agents Chemother. 2009 Dec;53(12):5039-45. doi: 10.1128/AAC.00633-09. Epub 2009 Sep 28.

13.

In vivo activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.

Hilliard JJ, Fernandez J, Melton J, Macielag MJ, Goldschmidt R, Bush K, Abbanat D.

Antimicrob Agents Chemother. 2009 May;53(5):2028-33. doi: 10.1128/AAC.00833-08. Epub 2009 Mar 9.

14.

New agents in development for the treatment of bacterial infections.

Abbanat D, Morrow B, Bush K.

Curr Opin Pharmacol. 2008 Oct;8(5):582-92. doi: 10.1016/j.coph.2008.08.001. Epub 2008 Sep 18. Review.

PMID:
18761107
15.

Synthesis and antibacterial activity of 3-keto-6-O-carbamoyl-11,12-cyclic thiocarbamate erythromycin A derivatives.

Zhu B, Marinelli BA, Abbanat D, Foleno BD, Bush K, Macielag MJ.

Bioorg Med Chem Lett. 2007 Jul 15;17(14):3900-4. Epub 2007 May 3.

PMID:
17502142
16.

In vitro antibacterial activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.

Foleno BD, Abbanat D, Goldschmidt RM, Flamm RK, Paget SD, Webb GC, Wira E, Macielag MJ, Bush K.

Antimicrob Agents Chemother. 2007 Jan;51(1):361-5. Epub 2006 Nov 13.

17.

Preparation of erythromycin analogs having functional groups at C-15.

Ashley GW, Burlingame M, Desai R, Fu H, Leaf T, Licari PJ, Tran C, Abbanat D, Bush K, Macielag M.

J Antibiot (Tokyo). 2006 Jul;59(7):392-401.

PMID:
17025015
18.

Synthesis and antibacterial activity of C6-carbazate ketolides.

Tennakoon MA, Henninger TC, Abbanat D, Foleno BD, Hilliard JJ, Bush K, Macielag MJ.

Bioorg Med Chem Lett. 2006 Dec 15;16(24):6231-5. Epub 2006 Sep 25.

PMID:
16997549
19.

Synthesis and antibacterial activity of 6-O-heteroarylcarbamoyl-11,12-lactoketolides.

Grant EB, Guiadeen D, Abbanat D, Foleno BD, Bush K, Macielag MJ.

Bioorg Med Chem Lett. 2006 Apr 1;16(7):1929-33. Epub 2006 Jan 30.

PMID:
16446089
20.

Utility of muropeptide ligase for identification of inhibitors of the cell wall biosynthesis enzyme MurF.

Baum EZ, Crespo-Carbone SM, Abbanat D, Foleno B, Maden A, Goldschmidt R, Bush K.

Antimicrob Agents Chemother. 2006 Jan;50(1):230-6.

21.

Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase.

Robicsek A, Strahilevitz J, Jacoby GA, Macielag M, Abbanat D, Park CH, Bush K, Hooper DC.

Nat Med. 2006 Jan;12(1):83-8. Epub 2005 Dec 20.

PMID:
16369542
22.

Synthesis and antibacterial activity of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives.

Zhu B, Marinelli BA, Abbanat D, Foleno BD, Henninger TC, Bush K, Macielag MJ.

Bioorg Med Chem Lett. 2006 Feb 15;16(4):1054-9. Epub 2005 Nov 11.

PMID:
16289812
23.

Identification of a dithiazoline inhibitor of Escherichia coli L,D-carboxypeptidase A.

Baum EZ, Crespo-Carbone SM, Foleno B, Peng S, Hilliard JJ, Abbanat D, Goldschmidt R, Bush K.

Antimicrob Agents Chemother. 2005 Nov;49(11):4500-7.

24.

15-amido erythromycins: synthesis and in vitro activity of a new class of macrolide antibiotics.

Shaw SJ, Abbanat D, Ashley GW, Bush K, Foleno B, Macielag M, Zhang D, Myles DC.

J Antibiot (Tokyo). 2005 Mar;58(3):167-77.

PMID:
15895524
25.

Synthesis and antibacterial activity of C2-fluoro, C6-carbamate ketolides, and their C9-oximes.

Xu X, Henninger T, Abbanat D, Bush K, Foleno B, Hilliard J, Macielag M.

Bioorg Med Chem Lett. 2005 Feb 15;15(4):883-7.

PMID:
15686880
26.

In vitro activities of novel 2-fluoro-naphthyridine-containing ketolides.

Abbanat D, Webb G, Foleno B, Li Y, Macielag M, Montenegro D, Wira E, Bush K.

Antimicrob Agents Chemother. 2005 Jan;49(1):309-15.

27.

Synthesis and antibacterial activity of C-6 carbamate ketolides, a novel series of orally active ketolide antibiotics.

Henninger TC, Xu X, Abbanat D, Baum EZ, Foleno BD, Hilliard JJ, Bush K, Hlasta DJ, Macielag MJ.

Bioorg Med Chem Lett. 2004 Sep 6;14(17):4495-9.

PMID:
15357979
28.

Novel antibacterial agents for the treatment of serious Gram-positive infections.

Abbanat D, Macielag M, Bush K.

Expert Opin Investig Drugs. 2003 Mar;12(3):379-99. Review.

PMID:
12605562
29.

Yanuthones: novel metabolites from a marine isolate of Aspergillus niger.

Bugni TS, Abbanat D, Bernan VS, Maiese WM, Greenstein M, Van Wagoner RM, Ireland CM.

J Org Chem. 2000 Oct 20;65(21):7195-200. No abstract available.

PMID:
11031048
30.

Novel polyketide metabolites from a species of marine fungi.

Smith CJ, Abbanat D, Bernan VS, Maiese WM, Greenstein M, Jompa J, Tahir A, Ireland CM.

J Nat Prod. 2000 Jan;63(1):142-5.

PMID:
10650098
31.
32.

Hongoquercins, new antibacterial agents from the fungus LL-23G227: fermentation and biological activity.

Abbanat DA, Singh MP, Greenstein M.

J Antibiot (Tokyo). 1998 Aug;51(8):708-14.

33.

Cell wall active antifungal compounds produced by the marine fungus hypoxylon oceanicum LL-15G256. I. Taxonomy and fermentation.

Abbanat D, Leighton M, Maiese W, Jones EB, Pearce C, Greenstein M.

J Antibiot (Tokyo). 1998 Mar;51(3):296-302.

34.

Martinomycin, a new polyether antibiotic produced by Streptomyces salvialis. I. Taxonomy, fermentation and biological activity.

Bernan VS, Montenegro DA, Goodman JJ, Alluri MR, Carter GT, Abbanat DR, Pearce CJ, Maiese WM, Greenstein M.

J Antibiot (Tokyo). 1994 Dec;47(12):1434-41.

35.

Pyrroindomycins, novel antibiotics produced by Streptomyces rugosporus sp. LL-42D005. I. Isolation and structure determination.

Ding W, Williams DR, Northcote P, Siegel MM, Tsao R, Ashcroft J, Morton GO, Alluri M, Abbanat D, Maiese WM, et al.

J Antibiot (Tokyo). 1994 Nov;47(11):1250-7.

36.

Glycothiohexides, novel antibiotics produced by "Sebekia" sp. LL-14E605. I. Taxonomy, fermentation and biological evaluation.

Steinberg DA, Bernan VS, Montenegro DA, Abbanat DR, Pearce CJ, Korshalla JD, Jacobus NV, Petersen PJ, Mroczenski-Wildey MJ, Maiese WM, et al.

J Antibiot (Tokyo). 1994 Aug;47(8):887-93.

38.
40.

Biosynthesis of a sulfonolipid in gliding bacteria.

Abbanat DR, Godchaux W 3rd, Polychroniou G, Leadbetter ER.

Biochem Biophys Res Commun. 1985 Jul 31;130(2):873-8.

PMID:
2992489

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