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Items: 43

1.

DNA methylation processes in atheosclerotic plaque.

Aavik E, Babu M, Ylä-Herttuala S.

Atherosclerosis. 2019 Feb;281:168-179. doi: 10.1016/j.atherosclerosis.2018.12.006. Epub 2018 Dec 18. Review.

PMID:
30591183
2.

Therapeutic effects of rosuvastatin in hypercholesterolemic prediabetic mice in the absence of low density lipoprotein receptor.

Gurzeler E, Aavik E, Laine A, Valkama T, Niskanen H, Huusko J, Kaikkonen MU, Ylä-Herttuala S.

Biochim Biophys Acta Gen Subj. 2019 Feb;1863(2):481-490. doi: 10.1016/j.bbagen.2018.11.012. Epub 2018 Nov 30.

PMID:
30508567
3.

Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells.

Moreau PR, Örd T, Downes NL, Niskanen H, Bouvy-Liivrand M, Aavik E, Ylä-Herttuala S, Kaikkonen MU.

Front Cardiovasc Med. 2018 Nov 5;5:159. doi: 10.3389/fcvm.2018.00159. eCollection 2018.

4.

Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions.

Siemelink MA, van der Laan SW, Haitjema S, van Koeverden ID, Schaap J, Wesseling M, de Jager SCA, Mokry M, van Iterson M, Dekkers KF, Luijk R, Foroughi Asl H, Michoel T, Björkegren JLM, Aavik E, Ylä-Herttuala S, de Borst GJ, Asselbergs FW, El Azzouzi H, den Ruijter HM, Heijmans BT, Pasterkamp G.

Circ Genom Precis Med. 2018 Sep;11(9):e002030. doi: 10.1161/CIRCGEN.117.002030.

PMID:
30354327
5.

Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial Infarction.

Kaikkonen MU, Halonen P, Liu OH, Turunen TA, Pajula J, Moreau P, Selvarajan I, Tuomainen T, Aavik E, Tavi P, Ylä-Herttuala S.

Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001702. doi: 10.1161/CIRCGENETICS.117.001702.

PMID:
28611032
6.

Global DNA methylation analysis of human atherosclerotic plaques reveals extensive genomic hypomethylation and reactivation at imprinted locus 14q32 involving induction of a miRNA cluster.

Aavik E, Lumivuori H, Leppänen O, Wirth T, Häkkinen SK, Bräsen JH, Beschorner U, Zeller T, Braspenning M, van Criekinge W, Mäkinen K, Ylä-Herttuala S.

Eur Heart J. 2015 Apr 21;36(16):993-1000. doi: 10.1093/eurheartj/ehu437. Epub 2014 Nov 16.

PMID:
25411193
7.

Modified RNA kick-starts cardiac repair.

Ylä-Herttuala S, Aavik E.

Nat Biotechnol. 2013 Oct;31(10):891-2. doi: 10.1038/nbt.2716. No abstract available.

PMID:
24104754
8.

Epigenetic regulation in vascular cells.

Turunen MP, Aavik E, Ylä-Herttuala S.

Curr Opin Lipidol. 2013 Oct;24(5):438-43. doi: 10.1097/MOL.0b013e328364292d. Review.

PMID:
23872638
9.

Epigenetics and atherosclerosis.

Turunen MP, Aavik E, Ylä-Herttuala S.

Biochim Biophys Acta. 2009 Sep;1790(9):886-91. doi: 10.1016/j.bbagen.2009.02.008. Epub 2009 Feb 21. Review.

PMID:
19233248
10.

Mechanisms behind the synergistic effect of sirolimus and imatinib in preventing restenosis after intimal injury.

Tigerstedt NM, Aavik E, Lehti S, Hayry P, Savolainen-Peltonen H.

J Vasc Res. 2009;46(3):240-52. doi: 10.1159/000167272. Epub 2008 Nov 4.

11.

Vasculoprotective effects of somatostatin receptor subtypes.

Tigerstedt NM, Aavik E, Aavik S, Savolainen-Peltonen H, Hayry P.

Mol Cell Endocrinol. 2007 Dec 15;279(1-2):34-8. Epub 2007 Sep 11.

PMID:
17945410
12.

Clinical predictors of renal allograft histopathology: a comparative study of single-lesion histology versus a composite, quantitative scoring system.

Yilmaz S, McLaughlin K, Paavonen T, Taskinen E, Monroy M, Aavik E, Vamvakopoulos J, Häyry P.

Transplantation. 2007 Mar 27;83(6):671-6.

PMID:
17414693
13.

Luciferase imaging for evaluation of oncolytic adenovirus replication in vivo.

Guse K, Dias JD, Bauerschmitz GJ, Hakkarainen T, Aavik E, Ranki T, Pisto T, Särkioja M, Desmond RA, Kanerva A, Hemminki A.

Gene Ther. 2007 Jun;14(11):902-11. Epub 2007 Mar 22.

PMID:
17377596
14.

Synergistic suppression of rat neointimal hyperplasia by rapamycin and imatinib mesylate: implications for the prevention of accelerated arteriosclerosis.

Vamvakopoulos JE, Petrov L, Aavik S, Lehti S, Aavik E, Hayry P.

J Vasc Res. 2006;43(2):184-92. Epub 2006 Jan 12.

PMID:
16410681
15.

Chronic rejection: prospects for therapeutic intervention in fibroproliferative vascular disease.

Häyry P, Aavik E, Sarwal M, du Toit D, Vamvakopoulos J.

Exp Clin Transplant. 2003 Jun;1(1):35-8. Review.

16.

Correlation between gene expression and morphological alterations in baboon carotid after balloon dilatation injury.

Aavik E, Mahapatra A, Boldrick J, Chen X, Barry C, Dutoit D, Sarwal M, Häyry P.

FASEB J. 2005 Jan;19(1):130-2. Epub 2004 Oct 20.

PMID:
15496494
17.

Protocol core needle biopsy and histological chronic allograft damage index as surrogate endpoint for Long-Term graft survival.

Hayry P, Paavonen T, Taskinen E, Tomlanovich E, Mathew T, Navarro M, Ramos E, Hooftman L, Vamvakopoulos J, Aavik E, Yilmaz S.

Transplant Proc. 2004 Jan-Feb;36(1):89-91.

PMID:
15013309
18.

Rational drug design: making drugs that make a difference.

Häyry P, du Toit D, Sarwal M, Aavik E, Hoffrén A, Vamvakopoulos J.

Transplant Proc. 2002 Sep;34(6):2000-2. Review. No abstract available.

PMID:
12270291
19.

Elimination of vascular fibrointimal hyperplasia by somatostatin receptor 1,4-selective agonist.

Aavik E, Luoto NM, Petrov L, Aavik S, Patel YC, Hayry P.

FASEB J. 2002 May;16(7):724-6. Epub 2002 Mar 26.

PMID:
11923215
20.

Expression of estrogen receptor sub-types alpha and beta in acute and chronic cardiac allograft vasculopathy.

Savolainen H, Frösen J, Petrov L, Aavik E, Häyry P.

J Heart Lung Transplant. 2001 Dec;20(12):1252-64.

PMID:
11744408
21.

Estrogen receptor beta dominates in baboon carotid after endothelial denudation injury.

Aavik E, du Toit D, Myburgh E, Frösen J, Hayry P.

Mol Cell Endocrinol. 2001 Aug 20;182(1):91-8.

PMID:
11500242
22.

Structure of carotid artery in baboon and rat and differences in their response to endothelial denudation angioplasty.

Du Toit D, Aavik E, Taskinen E, Myburgh E, Aaltola E, Aimonen M, Aavik S, van Wyk J, Häyry P.

Ann Med. 2001 Feb;33(1):63-78.

PMID:
11310941
23.

Molecular biology of transplant arteriosclerosis and sites of therapeutic intervention.

Häyry P, Aavik E, Palgi M, Petrov L, Savolainen H, Luoto NM, Loubtchenkov M, Frösen J.

Transplant Proc. 2001 Feb-Mar;33(1-2):293-4. No abstract available.

PMID:
11266824
24.

Emerging therapeutic strategies for the prevention and treatment of chronic allograft rejection.

Häyry P, Savolainen H, Luoto NM, Petrov L, Loubtchenkov M, Aavik E.

Transplant Proc. 2000 May;32(3):519. No abstract available.

PMID:
10812093
25.

Mechanisms of chronic rejection.

Häyry P, Aavik E, Savolainen H.

Transplant Proc. 1999 Nov;31(7A):5S-8S. Review. No abstract available.

PMID:
10576033
26.

Role of platelet-derived growth factor in obliterative bronchiolitis (chronic rejection) in the rat.

Kallio EA, Koskinen PK, Aavik E, Buchdunger E, Lemström KB.

Am J Respir Crit Care Med. 1999 Oct;160(4):1324-32.

PMID:
10508825
27.

High endothelial cells synthesize and degrade sLex. Putative implications for L-selectin-dependent recognition.

Majuri ML, Räbinä J, Niittymäki J, Tiisala S, Mattila P, Aavik E, Miyasaka M, Renkonen O, Renkonen R.

FEBS Lett. 1999 Jul 16;455(1-2):97-100.

28.

Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta.

Mäkelä S, Savolainen H, Aavik E, Myllärniemi M, Strauss L, Taskinen E, Gustafsson JA, Häyry P.

Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):7077-82.

29.

Role of nitric oxide in experimental obliterative bronchiolitis (chronic rejection) in the rat.

Kallio EA, Koskinen PK, Aavik E, Vaali K, Lemstöm KB.

J Clin Invest. 1997 Dec 15;100(12):2984-94.

30.

Role of growth factors in graft vessel disease.

Häyry P, Myllärniemi M, Aavik E, Loubtschenkov M, Ramirez LC.

Transplant Proc. 1997 Sep;29(6):2551. No abstract available.

PMID:
9290736
31.

Immunobiology and pathology of chronic rejection.

Häyry P, Myllärniemi M, Calderon Ramirez L, Aavik E, Loubtchenkov M, Koskinen P, Lemström K, Räisänen-Sokolowski A.

Transplant Proc. 1997 Feb-Mar;29(1-2):77-8. Review. No abstract available.

PMID:
9123163
32.

Chronic rejection: potential new sites of therapy.

Häyry P, Myllärniemi M, Aavik E, Lemström K, Koskinen P.

Transplant Proc. 1996 Dec;28(6):3225-6. Review. No abstract available.

PMID:
8962248
34.

Chronic allograft rejection.

Häyry P, Myllärniemi M, Aavik E.

Transplant Proc. 1996 Aug;28(4):2337-8. Review. No abstract available.

PMID:
8769244
35.

Stabile D-peptide analog of insulin-like growth factor-1 inhibits smooth muscle cell proliferation after carotid ballooning injury in the rat.

Häyry P, Myllärniemi M, Aavik E, Alatalo S, Aho P, Yilmaz S, Räisänen-Sokolowski A, Cozzone G, Jameson BA, Baserga R.

FASEB J. 1995 Oct;9(13):1336-44.

PMID:
7557024
36.

Steroid 21-hydroxylase gene polymorphism in Addison's disease patients.

Peterson P, Partanen J, Aavik E, Salmi H, Pelkonen R, Krohn KJ.

Tissue Antigens. 1995 Jul;46(1):63-7. No abstract available.

PMID:
7482499
37.
38.

Autoantibodies to cytochrome P450 enzymes P450scc, P450c17, and P450c21 in autoimmune polyglandular disease types I and II and in isolated Addison's disease.

Uibo R, Aavik E, Peterson P, Perheentupa J, Aranko S, Pelkonen R, Krohn KJ.

J Clin Endocrinol Metab. 1994 Feb;78(2):323-8.

PMID:
8106620
39.

Effect of mutations in rev gene of SIVmac on virus replication.

Aavik E, Hakkarainen K, Krohn KJ.

AIDS Res Hum Retroviruses. 1994;10 Suppl 2:S123-8.

PMID:
7865286
40.
41.

Transcomplementation of simian immunodeficiency virus Rev with human T-cell leukemia virus type I Rex.

Krohn KJ, Hakkarainen K, Aavik E, Dewhurst S, Sadaie R, Mullins JI.

J Virol. 1993 Sep;67(9):5681-4.

42.

Identification by molecular cloning of an autoantigen associated with Addison's disease as steroid 17 alpha-hydroxylase.

Krohn K, Uibo R, Aavik E, Peterson P, Savilahti K.

Lancet. 1992 Mar 28;339(8796):770-3.

PMID:
1347802
43.

[A new vector of direct selection of recombinants for Escherichia coli].

Aavik EE, Kheĭnaru AL.

Dokl Akad Nauk SSSR. 1988;302(3):718-20. Russian. No abstract available.

PMID:
3068027

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