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Items: 7


Synovial IL-21/TNF-producing CD4+ T cells induce joint destruction in rheumatoid arthritis by inducing matrix metalloproteinase production by fibroblast-like synoviocytes.

Lebre MC, Vieira PL, Tang MW, Aarrass S, Helder B, Newsom-Davis T, Tak PP, Screaton GR.

J Leukoc Biol. 2017 Mar;101(3):775-783. doi: 10.1189/jlb.5A0516-217RR. Epub 2016 Oct 12.


Reduced CLEC9A expression in synovial tissue of psoriatic arthritis patients after adalimumab therapy.

Ramos MI, Teunissen MB, Helder B, Aarrass S, de Hair MJ, van Kuijk AW, Gerlag DM, Tak PP, Lebre MC.

Rheumatology (Oxford). 2016 Sep;55(9):1575-84. doi: 10.1093/rheumatology/kew204. Epub 2016 May 13.


Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?

van Baarsen LG, Lebre MC, van der Coelen D, Aarrass S, Tang MW, Ramwadhdoebe TH, Gerlag DM, Tak PP.

Arthritis Res Ther. 2014 Aug 22;16(4):426. doi: 10.1186/s13075-014-0426-z.


FMS-related tyrosine kinase 3 ligand (Flt3L)/CD135 axis in rheumatoid arthritis.

Ramos MI, Perez SG, Aarrass S, Helder B, Broekstra P, Gerlag DM, Reedquist KA, Tak PP, Lebre MC.

Arthritis Res Ther. 2013;15(6):R209.


Absence of Fms-like tyrosine kinase 3 ligand (Flt3L) signalling protects against collagen-induced arthritis.

Ramos MI, Karpus ON, Broekstra P, Aarrass S, Jacobsen SE, Tak PP, Lebre MC.

Ann Rheum Dis. 2015 Jan;74(1):211-9. doi: 10.1136/annrheumdis-2013-203371. Epub 2013 Sep 24.


Why CCR2 and CCR5 blockade failed and why CCR1 blockade might still be effective in the treatment of rheumatoid arthritis.

Lebre MC, Vergunst CE, Choi IY, Aarrass S, Oliveira AS, Wyant T, Horuk R, Reedquist KA, Tak PP.

PLoS One. 2011;6(7):e21772. doi: 10.1371/journal.pone.0021772. Epub 2011 Jul 1.


Transcriptional profiling reveals novel markers of liver fibrogenesis: gremlin and insulin-like growth factor-binding proteins.

Boers W, Aarrass S, Linthorst C, Pinzani M, Elferink RO, Bosma P.

J Biol Chem. 2006 Jun 16;281(24):16289-95. Epub 2006 Apr 10.

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