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Items: 1 to 50 of 54

1.

The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function.

Chellappa S, Kushekhar K, Munthe LA, Tjønnfjord GE, Aandahl EM, Okkenhaug K, Taskén K.

J Immunol. 2019 Jan 28. pii: ji1701703. doi: 10.4049/jimmunol.1701703. [Epub ahead of print]

PMID:
30692213
2.

Transcriptional profiling reveals monocyte-related macrophages phenotypically resembling DC in human intestine.

Richter L, Landsverk OJB, Atlasy N, Bujko A, Yaqub S, Horneland R, Øyen O, Aandahl EM, Lundin KEA, Stunnenberg HG, Bækkevold ES, Jahnsen FL.

Mucosal Immunol. 2018 Sep;11(5):1512-1523. doi: 10.1038/s41385-018-0060-1. Epub 2018 Jul 23.

PMID:
30038215
3.

Pancreas transplant rejection episodes are not revealed by biopsies of the donor duodenum in a prospective study with paired biopsies.

Nordheim E, Horneland R, Aandahl EM, Grzyb K, Aabakken L, Paulsen V, Midtvedt K, Hartmann A, Jenssen T.

Am J Transplant. 2018 May;18(5):1256-1261. doi: 10.1111/ajt.14658. Epub 2018 Feb 3.

PMID:
29316221
4.

Transcriptional and functional profiling defines human small intestinal macrophage subsets.

Bujko A, Atlasy N, Landsverk OJB, Richter L, Yaqub S, Horneland R, Øyen O, Aandahl EM, Aabakken L, Stunnenberg HG, Bækkevold ES, Jahnsen FL.

J Exp Med. 2018 Feb 5;215(2):441-458. doi: 10.1084/jem.20170057. Epub 2017 Dec 22.

5.

Outcomes in Pancreas Transplantation With Exocrine Drainage Through a Duodenoduodenostomy Versus Duodenojejunostomy.

Lindahl JP, Horneland R, Nordheim E, Hartmann A, Aandahl EM, Grzyb K, Haugaa H, Kjøsen G, Åsberg A, Jenssen T.

Am J Transplant. 2018 Jan;18(1):154-162. doi: 10.1111/ajt.14420. Epub 2017 Aug 23.

6.

Antibody-secreting plasma cells persist for decades in human intestine.

Landsverk OJ, Snir O, Casado RB, Richter L, Mold JE, Réu P, Horneland R, Paulsen V, Yaqub S, Aandahl EM, Øyen OM, Thorarensen HS, Salehpour M, Possnert G, Frisén J, Sollid LM, Baekkevold ES, Jahnsen FL.

J Exp Med. 2017 Feb;214(2):309-317. doi: 10.1084/jem.20161590. Epub 2017 Jan 19.

7.

CD8+ T Cells That Coexpress RORγt and T-bet Are Functionally Impaired and Expand in Patients with Distal Bile Duct Cancer.

Chellappa S, Hugenschmidt H, Hagness M, Subramani S, Melum E, Line PD, Labori KJ, Wiedswang G, Taskén K, Aandahl EM.

J Immunol. 2017 Feb 15;198(4):1729-1739. doi: 10.4049/jimmunol.1600061. Epub 2017 Jan 4.

8.

Regulatory T cells that co-express RORγt and FOXP3 are pro-inflammatory and immunosuppressive and expand in human pancreatic cancer.

Chellappa S, Hugenschmidt H, Hagness M, Line PD, Labori KJ, Wiedswang G, Taskén K, Aandahl EM.

Oncoimmunology. 2015 Oct 29;5(4):e1102828. eCollection 2016 Apr.

9.

Human regulatory T cells control TCR signaling and susceptibility to suppression in CD4+ T cells.

Chellappa S, Lieske NV, Hagness M, Line PD, Taskén K, Aandahl EM.

J Leukoc Biol. 2016 Jul;100(1):5-16. doi: 10.1189/jlb.2HI0815-334R. Epub 2015 Dec 29.

PMID:
26715685
10.

Transplantation With Livers From Deceased Donors Older Than 75 Years.

Thorsen T, Aandahl EM, Bennet W, Olausson M, Ericzon BG, Nowak G, Duraj F, Isoniemi H, Rasmussen A, Karlsen TH, Foss A.

Transplantation. 2015 Dec;99(12):2534-42. doi: 10.1097/TP.0000000000000728.

PMID:
25909464
11.

Liver transplantation with deceased ABO-incompatible donors is life-saving but associated with increased risk of rejection and post-transplant complications.

Thorsen T, Dahlgren US, Aandahl EM, Grzyb K, Karlsen TH, Boberg KM, Rydberg L, Naper C, Foss A, Bennet W.

Transpl Int. 2015 Jul;28(7):800-12. doi: 10.1111/tri.12552.

12.

Low use of surveillance and early diagnosis of hepatocellular carcinoma in Norway--a population-based cohort study.

Eskesen AN, Bjøro K, Aandahl EM, Line PD, Melum E.

Cancer Epidemiol. 2014 Dec;38(6):741-7.

PMID:
25454262
13.

Activated regulatory and memory T-cells accumulate in malignant ascites from ovarian carcinoma patients.

Landskron J, Helland Ø, Torgersen KM, Aandahl EM, Gjertsen BT, Bjørge L, Taskén K.

Cancer Immunol Immunother. 2015 Mar;64(3):337-47. doi: 10.1007/s00262-014-1636-6. Epub 2014 Nov 22.

PMID:
25416072
14.

Pancreas transplantation with enteroanastomosis to native duodenum poses technical challenges--but offers improved endoscopic access for scheduled biopsies and therapeutic interventions.

Horneland R, Paulsen V, Lindahl JP, Grzyb K, Eide TJ, Lundin K, Aabakken L, Jenssen T, Aandahl EM, Foss A, Øyen O.

Am J Transplant. 2015 Jan;15(1):242-50. doi: 10.1111/ajt.12953. Epub 2014 Nov 13.

15.

T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses.

Skånland SS, Moltu K, Berge T, Aandahl EM, Taskén K.

Biochem J. 2014 Jun 15;460(3):399-410. doi: 10.1042/BJ20140040.

PMID:
24665965
16.

Aggressive treatment of patients with metastatic colorectal cancer increases survival: a scandinavian single-center experience.

Brudvik KW, Bains SJ, Seeberg LT, Labori KJ, Waage A, Taskén K, Aandahl EM, Bjørnbeth BA.

HPB Surg. 2013;2013:727095. doi: 10.1155/2013/727095. Epub 2013 Jun 6.

17.

Kinetics and activation requirements of contact-dependent immune suppression by human regulatory T cells.

Hagness M, Henjum K, Landskron J, Brudvik KW, Bjørnbeth BA, Foss A, Taskén K, Aandahl EM.

J Immunol. 2012 Jun 1;188(11):5459-66. doi: 10.4049/jimmunol.1101367. Epub 2012 Apr 25.

18.

Protein kinase A antagonist inhibits β-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in Apc(Min/+) mice.

Brudvik KW, Paulsen JE, Aandahl EM, Roald B, Taskén K.

Mol Cancer. 2011 Dec 15;10:149. doi: 10.1186/1476-4598-10-149.

19.

Regulatory T-cell-mediated inhibition of antitumor immune responses is associated with clinical outcome in patients with liver metastasis from colorectal cancer.

Brudvik KW, Henjum K, Aandahl EM, Bjørnbeth BA, Taskén K.

Cancer Immunol Immunother. 2012 Jul;61(7):1045-53. doi: 10.1007/s00262-011-1174-4. Epub 2011 Dec 11.

PMID:
22159472
20.

CD147 (Basigin/Emmprin) identifies FoxP3+CD45RO+CTLA4+-activated human regulatory T cells.

Solstad T, Bains SJ, Landskron J, Aandahl EM, Thiede B, Taskén K, Torgersen KM.

Blood. 2011 Nov 10;118(19):5141-51. doi: 10.1182/blood-2011-02-339242. Epub 2011 Sep 21.

21.

An exploratory trial of cyclooxygenase type 2 inhibitor in HIV-1 infection: downregulated immune activation and improved T cell-dependent vaccine responses.

Pettersen FO, Torheim EA, Dahm AE, Aaberge IS, Lind A, Holm M, Aandahl EM, Sandset PM, Taskén K, Kvale D.

J Virol. 2011 Jul;85(13):6557-66. doi: 10.1128/JVI.00073-11. Epub 2011 Apr 13.

22.

Inflammation versus adaptive immunity in cancer pathogenesis.

Yaqub S, Aandahl EM.

Crit Rev Oncog. 2009;15(1-2):43-63. Review.

PMID:
20136627
23.

A novel human CD4+ T-cell inducer subset with potent immunostimulatory properties.

Ndhlovu LC, Leal FE, Eccles-James IG, Jha AR, Lanteri M, Norris PJ, Barbour JD, Wachter DJ, Andersson J, Taskén K, Torheim EA, Aandahl EM, Kallas EG, Nixon DF.

Eur J Immunol. 2010 Jan;40(1):134-41. doi: 10.1002/eji.200939258.

24.

Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population.

Torheim EA, Ndhlovu LC, Pettersen FO, Larsen TL, Jha AR, Torgersen KM, Kvale D, Nixon DF, Taskén K, Aandahl EM.

Eur J Immunol. 2009 May;39(5):1280-7. doi: 10.1002/eji.200839002.

25.

CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype?

Aandahl EM, Torgersen KM, Taskén K.

Hum Immunol. 2008 Nov;69(11):696-9. doi: 10.1016/j.humimm.2008.08.291. Epub 2008 Sep 24. Review.

PMID:
18817824
26.

Human naturally occurring and adaptive regulatory T cells secrete high levels of leukaemia inhibitory factor upon activation.

Mahic M, Kalland ME, Aandahl EM, Torgersen KM, Taskén K.

Scand J Immunol. 2008 Oct;68(4):391-6. doi: 10.1111/j.1365-3083.2008.02148.x.

27.

Inhibition of protein kinase A improves effector function of monocytes from HIV-infected patients.

Bryn T, Mahic M, Aandahl EM, Frøland SS, Aukrust P, Taskén K.

AIDS Res Hum Retroviruses. 2008 Jul;24(7):1013-5. doi: 10.1089/aid.2008.0071. No abstract available.

PMID:
18593346
28.

Molecular architecture of signal complexes regulating immune cell function.

Torgersen KM, Aandahl EM, Taskén K.

Handb Exp Pharmacol. 2008;(186):327-63. doi: 10.1007/978-3-540-72843-6_14. Review.

PMID:
18491059
29.

Differentiation of naive CD4+ T cells into CD4+CD25+FOXP3+ regulatory T cells by continuous antigen stimulation.

Mahic M, Yaqub S, Bryn T, Henjum K, Eide DM, Torgersen KM, Aandahl EM, Taskén K.

J Leukoc Biol. 2008 May;83(5):1111-7. doi: 10.1189/jlb.0507329. Epub 2008 Feb 12.

PMID:
18270250
30.

Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation.

Mahic M, Henjum K, Yaqub S, Bjørnbeth BA, Torgersen KM, Taskén K, Aandahl EM.

Eur J Immunol. 2008 Mar;38(3):640-6. doi: 10.1002/eji.200737529.

31.

LPS-activated monocytes suppress T-cell immune responses and induce FOXP3+ T cells through a COX-2-PGE2-dependent mechanism.

Bryn T, Yaqub S, Mahic M, Henjum K, Aandahl EM, Taskén K.

Int Immunol. 2008 Feb;20(2):235-45. Epub 2007 Dec 20.

PMID:
18156149
32.

Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner.

Yaqub S, Henjum K, Mahic M, Jahnsen FL, Aandahl EM, Bjørnbeth BA, Taskén K.

Cancer Immunol Immunother. 2008 Jun;57(6):813-21. Epub 2007 Oct 26.

PMID:
17962941
33.

Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin.

Ruppelt A, Mosenden R, Grönholm M, Aandahl EM, Tobin D, Carlson CR, Abrahamsen H, Herberg FW, Carpén O, Taskén K.

J Immunol. 2007 Oct 15;179(8):5159-68. Erratum in: J Immunol. 2011 Jun 15;186(12):7269-71.

34.
35.
36.

Immune modulatory effects of cyclooxygenase type 2 inhibitors in HIV patients on combination antiretroviral treatment.

Kvale D, Ormaasen V, Kran AM, Johansson CC, Aukrust P, Aandahl EM, Frøland SS, Taskén K.

AIDS. 2006 Apr 4;20(6):813-20.

PMID:
16549964
37.

CD4+CD25+ regulatory T cells in HIV infection.

Nixon DF, Aandahl EM, Michaëlsson J.

Microbes Infect. 2005 Jun;7(7-8):1063-5. Epub 2005 Apr 15. Review.

PMID:
15893493
38.

Cyclo-oxygenase type 2-dependent prostaglandin E2 secretion is involved in retrovirus-induced T-cell dysfunction in mice.

Rahmouni S, Aandahl EM, Nayjib B, Zeddou M, Giannini S, Verlaet M, Greimers R, Boniver J, Tasken K, Moutschen M.

Biochem J. 2004 Dec 15;384(Pt 3):469-76.

39.

Expansion of CD7(low) and CD7(negative) CD8 T-cell effector subsets in HIV-1 infection: correlation with antigenic load and reversion by antiretroviral treatment.

Aandahl EM, Quigley MF, Moretto WJ, Moll M, Gonzalez VD, Sönnerborg A, Lindbäck S, Hecht FM, Deeks SG, Rosenberg MG, Nixon DF, Sandberg JK.

Blood. 2004 Dec 1;104(12):3672-8. Epub 2004 Aug 12.

40.

New observations on CD8 cell responses.

Nixon DF, Aandahl EM, Sandberg JK.

AIDS. 2003;17 Suppl 4:S61-5. Review. No abstract available.

PMID:
15080181
41.

Treatment with type-2 selective and non-selective cyclooxygenase inhibitors improves T-cell proliferation in HIV-infected patients on highly active antiretroviral therapy.

Johansson CC, Bryn T, Aandahl EM, Areklett MA, Aukrust P, Taskén K, Frøland SS.

AIDS. 2004 Apr 9;18(6):951-2. No abstract available.

PMID:
15060445
42.

Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens.

Aandahl EM, Michaëlsson J, Moretto WJ, Hecht FM, Nixon DF.

J Virol. 2004 Mar;78(5):2454-9.

43.

Localized effects of cAMP mediated by distinct routes of protein kinase A.

Taskén K, Aandahl EM.

Physiol Rev. 2004 Jan;84(1):137-67. Review.

44.

PKAI as a potential target for therapeutic intervention.

Taskén K, Hansson V, Aukrust P, Frøland S, Skålhegg BS, Müller F, Tobin D, Vang T, Torgersen KM, Aandahl EM.

Drug News Perspect. 2000 Feb;13(1):12-8.

PMID:
12937648
45.

Impaired secretion of IL-10 by T cells from patients with common variable immunodeficiency--involvement of protein kinase A type I.

Holm AM, Aukrust P, Aandahl EM, Müller F, Taskén K, Frøland SS.

J Immunol. 2003 Jun 1;170(11):5772-7.

46.

A winged helix forkhead (FOXD2) tunes sensitivity to cAMP in T lymphocytes through regulation of cAMP-dependent protein kinase RIalpha.

Johansson CC, Dahle MK, Blomqvist SR, Grønning LM, Aandahl EM, Enerbäck S, Taskén K.

J Biol Chem. 2003 May 9;278(19):17573-9. Epub 2003 Mar 5.

47.

CD7 is a differentiation marker that identifies multiple CD8 T cell effector subsets.

Aandahl EM, Sandberg JK, Beckerman KP, Taskén K, Moretto WJ, Nixon DF.

J Immunol. 2003 Mar 1;170(5):2349-55.

48.

Inhibition of antigen-specific T cell proliferation and cytokine production by protein kinase A type I.

Aandahl EM, Moretto WJ, Haslett PA, Vang T, Bryn T, Tasken K, Nixon DF.

J Immunol. 2002 Jul 15;169(2):802-8.

49.
50.

[Image of physicians as professionals].

Aandahl EM.

Tidsskr Nor Laegeforen. 1999 Nov 30;119(29):4371. Norwegian. No abstract available.

PMID:
10667143

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