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Items: 12


Down with doublespeak: NAIP/NLRC4 inflammasomes get specific.

Aachoui Y, Miao EA.

J Exp Med. 2016 May 2;213(5):646. doi: 10.1084/jem.2135insight1. No abstract available.


Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium.

Maltez VI, Tubbs AL, Cook KD, Aachoui Y, Falcone EL, Holland SM, Whitmire JK, Miao EA.

Immunity. 2015 Nov 17;43(5):987-97. doi: 10.1016/j.immuni.2015.10.010. Epub 2015 Nov 10.


Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.

Aachoui Y, Kajiwara Y, Leaf IA, Mao D, Ting JP, Coers J, Aderem A, Buxbaum JD, Miao EA.

Cell Host Microbe. 2015 Sep 9;18(3):320-32. doi: 10.1016/j.chom.2015.07.016. Epub 2015 Aug 27.


WildCARDs: inflammatory caspases directly detect LPS.

Hagar JA, Aachoui Y, Miao EA.

Cell Res. 2015 Feb;25(2):149-50. doi: 10.1038/cr.2014.128. Epub 2014 Sep 30.


Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.

Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA.

Science. 2013 Sep 13;341(6151):1250-3. doi: 10.1126/science.1240988.


Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection.

Aachoui Y, Sagulenko V, Miao EA, Stacey KJ.

Curr Opin Microbiol. 2013 Jun;16(3):319-26. doi: 10.1016/j.mib.2013.04.004. Epub 2013 May 23. Review.


Caspase-11 protects against bacteria that escape the vacuole.

Aachoui Y, Leaf IA, Hagar JA, Fontana MF, Campos CG, Zak DE, Tan MH, Cotter PA, Vance RE, Aderem A, Miao EA.

Science. 2013 Feb 22;339(6122):975-8. doi: 10.1126/science.1230751. Epub 2013 Jan 24.


Effects of small intestinal submucosa (SIS) on the murine innate immune microenvironment induced by heat-killed Staphylococcus aureus.

Roy Chowdhury R, Aachoui Y, Ghosh SK.

PLoS One. 2012;7(11):e48724. doi: 10.1371/journal.pone.0048724. Epub 2012 Nov 26.


Extracellular matrix from porcine small intestinal submucosa (SIS) as immune adjuvants.

Aachoui Y, Ghosh SK.

PLoS One. 2011;6(11):e27083. doi: 10.1371/journal.pone.0027083. Epub 2011 Nov 7.


Immune enhancement by novel vaccine adjuvants in autoimmune-prone NZB/W F1 mice: relative efficacy and safety.

Aachoui Y, Ghosh SK.

BMC Immunol. 2011 Oct 24;12:61. doi: 10.1186/1471-2172-12-61.


Synthetic adjuvants for vaccine formulations: evaluation of new phytol derivatives in induction and persistence of specific immune response.

Aachoui Y, Schulte ML, Fitch RW, Ghosh SK.

Cell Immunol. 2011;271(2):308-18. doi: 10.1016/j.cellimm.2011.07.009. Epub 2011 Jul 29.


Molecular signatures of phytol-derived immunostimulants in the context of chemokine-cytokine microenvironment and enhanced immune response.

Aachoui Y, Chowdhury RR, Fitch RW, Ghosh SK.

Cell Immunol. 2011;271(2):227-38. doi: 10.1016/j.cellimm.2011.07.001. Epub 2011 Jul 14.


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