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Items: 1 to 50 of 259

1.

Diacetyl and related flavorant α-Diketones: Biotransformation, cellular interactions, and respiratory-tract toxicity.

Anders MW.

Toxicology. 2017 Aug 1;388:21-29. doi: 10.1016/j.tox.2017.02.002. Epub 2017 Feb 5. Review.

PMID:
28179188
2.

Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein-Coupled Receptor Antagonist.

Stoveken HM, Bahr LL, Anders MW, Wojtovich AP, Smrcka AV, Tall GG.

Mol Pharmacol. 2016 Sep;90(3):214-24. doi: 10.1124/mol.116.104828. Epub 2016 Jun 23.

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Exploiting endobiotic metabolic pathways to target xenobiotic antioxidants to mitochondria.

Anders MW.

Mitochondrion. 2013 Sep;13(5):454-63. doi: 10.1016/j.mito.2012.10.015. Epub 2012 Nov 1. Review.

PMID:
23123918
5.

Glutathione transferase zeta: discovery, polymorphic variants, catalysis, inactivation, and properties of Gstz1-/- mice.

Board PG, Anders MW.

Drug Metab Rev. 2011 May;43(2):215-25. doi: 10.3109/03602532.2010.549132. Epub 2011 Feb 8. Review.

PMID:
21303221
6.

Putting bioactivation reactions to work: Targeting antioxidants to mitochondria.

Anders MW.

Chem Biol Interact. 2011 Jun 30;192(1-2):8-13. doi: 10.1016/j.cbi.2010.10.004. Epub 2010 Nov 18. Review.

PMID:
20971100
7.

Comment on M.V. Evans and J.C. Caldwell: evaluation of two different metabolic hypotheses for dichloromethane toxicity using physiologically based pharmacokinetic modeling of in vivo gas uptake data exposure in female B6C3F1 mice, Toxicol. Appl. Pharmacol., 244, 280-290, 2010.

Anders MW, Andersen ME, Clewell HJ 3rd, Gargas ML, Guengerich FP, Reitz RH.

Toxicol Appl Pharmacol. 2010 Oct 1;248(1):63-4; author reply 65-7. doi: 10.1016/j.taap.2010.07.012. Epub 2010 Jul 22. No abstract available.

PMID:
20655322
8.

Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: a prodrug strategy for targeting cytoprotective antioxidants to mitochondria.

Roser KS, Brookes PS, Wojtovich AP, Olson LP, Shojaie J, Parton RL, Anders MW.

Bioorg Med Chem. 2010 Feb 15;18(4):1441-8. doi: 10.1016/j.bmc.2010.01.019. Epub 2010 Jan 15.

9.

S-(4-Nitrophenacyl)glutathione is a specific substrate for glutathione transferase omega 1-1.

Board PG, Coggan M, Cappello J, Zhou H, Oakley AJ, Anders MW.

Anal Biochem. 2008 Mar 1;374(1):25-30. Epub 2007 Sep 29.

PMID:
18028863
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12.

Mitochondria: new drug targets for oxidative stress-induced diseases.

Anders MW, Robotham JL, Sheu SS.

Expert Opin Drug Metab Toxicol. 2006 Feb;2(1):71-9. Review.

PMID:
16863469
13.

N-glucuronidation of perfluorooctanesulfonamide by human, rat, dog, and monkey liver microsomes and by expressed rat and human UDP-glucuronosyltransferases.

Xu L, Krenitsky DM, Seacat AM, Butenhoff JL, Tephly TR, Anders MW.

Drug Metab Dispos. 2006 Aug;34(8):1406-10. Epub 2006 May 23.

14.

Polymorphisms in the human glutathione transferase zeta promoter.

Fang YY, Kashkarov U, Anders MW, Board PG.

Pharmacogenet Genomics. 2006 May;16(5):307-13.

PMID:
16609361
15.

Workshop overview: reassessment of the cancer risk of dichloromethane in humans.

Starr TB, Matanoski G, Anders MW, Andersen ME.

Toxicol Sci. 2006 May;91(1):20-8. Epub 2006 Feb 28.

PMID:
16507920
16.

Human glutathione transferase zeta.

Board PG, Anders MW.

Methods Enzymol. 2005;401:61-77. Review.

PMID:
16399379
17.

Targeting antioxidants to mitochondria: a new therapeutic direction.

Sheu SS, Nauduri D, Anders MW.

Biochim Biophys Acta. 2006 Feb;1762(2):256-65. Epub 2005 Nov 8. Review.

18.

Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways.

Blackburn AC, Matthaei KI, Lim C, Taylor MC, Cappello JY, Hayes JD, Anders MW, Board PG.

Mol Pharmacol. 2006 Feb;69(2):650-7. Epub 2005 Nov 8.

19.

Formation and toxicity of anesthetic degradation products.

Anders MW.

Annu Rev Pharmacol Toxicol. 2005;45:147-76. Review.

PMID:
15832444
20.

Glutathione-dependent bioactivation of haloalkanes and haloalkenes.

Anders MW.

Drug Metab Rev. 2004 Oct;36(3-4):583-94. Review.

PMID:
15554237
21.

Calcium, ATP, and ROS: a mitochondrial love-hate triangle.

Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS.

Am J Physiol Cell Physiol. 2004 Oct;287(4):C817-33. Review.

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Perturbation of maleylacetoacetic acid metabolism in rats with dichloroacetic Acid-induced glutathione transferase zeta deficiency.

Lantum HB, Cornejo J, Pierce RH, Anders MW.

Toxicol Sci. 2003 Jul;74(1):192-202. Epub 2003 May 2.

PMID:
12730618
29.

Nephrotoxicity of chlorofluoroacetic acid in rats.

Lantum HB, Baggs RB, Krenitsky DM, Anders MW.

Toxicol Sci. 2002 Dec;70(2):261-8.

PMID:
12441371
30.

Mass spectral characterization of dichloroacetic acid-modified human glutathione transferase zeta.

Anderson WB, Liebler DC, Board PG, Anders MW.

Chem Res Toxicol. 2002 Nov;15(11):1387-97.

PMID:
12437329
31.
32.

Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism.

Cooper AJ, Bruschi SA, Anders MW.

Biochem Pharmacol. 2002 Aug 15;64(4):553-64. Review.

PMID:
12167474
34.

Molecular identification of a novel carnitine transporter specific to human testis. Insights into the mechanism of carnitine recognition.

Enomoto A, Wempe MF, Tsuchida H, Shin HJ, Cha SH, Anzai N, Goto A, Sakamoto A, Niwa T, Kanai Y, Anders MW, Endou H.

J Biol Chem. 2002 Sep 27;277(39):36262-71. Epub 2002 Jun 27.

35.

Immunohistochemical localization and activity of glutathione transferase zeta (GSTZ1-1) in rat tissues.

Lantum HB, Baggs RB, Krenitsky DM, Board PG, Anders MW.

Drug Metab Dispos. 2002 Jun;30(6):616-25.

36.

Biotransformation of 1,1,1,3,3-Pentafluoropropane (HFC-245fa).

Bayer T, Amberg A, Bertermann R, Rusch GM, Anders MW, Dekant W.

Chem Res Toxicol. 2002 May;15(5):723-33.

PMID:
12018995
37.

Alkylation and inactivation of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone.

Lantum HB, Liebler DC, Board PG, Anders MW.

Chem Res Toxicol. 2002 May;15(5):707-16.

PMID:
12018993
39.

Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition.

Uchino H, Kanai Y, Kim DK, Wempe MF, Chairoungdua A, Morimoto E, Anders MW, Endou H.

Mol Pharmacol. 2002 Apr;61(4):729-37.

40.

Inactivation of polymorphic variants of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone.

Lantum HB, Board PG, Anders MW.

Adv Exp Med Biol. 2001;500:339-42. No abstract available.

PMID:
11764965
41.

Formation and fate of reactive intermediates of haloalkanes, haloalkenes, and alpha-haloacids.

Anders MW.

Adv Exp Med Biol. 2001;500:113-20. Review. No abstract available.

PMID:
11764921
42.

GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase.

Blackburn AC, Coggan M, Tzeng HF, Lantum H, Polekhina G, Parker MW, Anders MW, Board PG.

Pharmacogenetics. 2001 Nov;11(8):671-8.

PMID:
11692075
43.

Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1.

Pombrio JM, Giangreco A, Li L, Wempe MF, Anders MW, Sweet DH, Pritchard JB, Ballatori N.

Mol Pharmacol. 2001 Nov;60(5):1091-9.

44.

Efflux of glutathione conjugate of monochlorobimane from striatal and cortical neurons.

DeCory HH, Piech-Dumas KM, Sheu SS, Federoff HJ, Anders MW.

Drug Metab Dispos. 2001 Oct;29(10):1256-62.

45.

Identification of novel glutathione transferases and polymorphic variants by expressed sequence tag database analysis.

Board PG, Chelvanayagam G, Jermiin LS, Tetlow N, Tzeng HF, Anders MW, Blackburn AC.

Drug Metab Dispos. 2001 Apr;29(4 Pt 2):544-7.

46.

Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis.

Chen Y, Cai J, Anders MW, Stevens JL, Jones DP.

Toxicol Appl Pharmacol. 2001 Feb 1;170(3):172-80.

PMID:
11162782
47.

Bioactivation mechanisms of haloalkene cysteine S-conjugates modeled by gas-phase, ion-molecule reactions.

Luu NC, Iyer RA, Anders MW, Ridge DP.

Chem Res Toxicol. 2000 Jul;13(7):610-5.

PMID:
10898593
48.
49.

Polymorphism- and species-dependent inactivation of glutathione transferase zeta by dichloroacetate.

Tzeng HF, Blackburn AC, Board PG, Anders MW.

Chem Res Toxicol. 2000 Apr;13(4):231-6.

PMID:
10775321
50.

Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis.

Blackburn AC, Tzeng HF, Anders MW, Board PG.

Pharmacogenetics. 2000 Feb;10(1):49-57.

PMID:
10739172

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