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Items: 31

1.

Constraints, Trade-offs and the Currency of Fitness.

Acerenza L.

J Mol Evol. 2016 Mar;82(2-3):117-27. doi: 10.1007/s00239-016-9730-3. Epub 2016 Feb 26. Review.

PMID:
26920684
2.

A modular modulation method for achieving increases in metabolite production.

Acerenza L, Monzon P, Ortega F.

Biotechnol Prog. 2015 May-Jun;31(3):656-67. doi: 10.1002/btpr.2059. Epub 2015 Mar 23.

PMID:
25683235
3.

Source and regulation of flux variability in Escherichia coli.

San Román M, Cancela H, Acerenza L.

BMC Syst Biol. 2014 Jun 14;8:67. doi: 10.1186/1752-0509-8-67.

4.

Regulatory design in a simple system integrating membrane potential generation and metabolic ATP consumption. Robustness and the role of energy dissipating processes.

Acerenza L, Cristina E, Hernández JA.

Biochim Biophys Acta. 2011 Dec;1807(12):1634-46. doi: 10.1016/j.bbabio.2011.09.003. Epub 2011 Sep 14.

5.

Modular metabolic control analysis of large responses in branched systems--application to aspartate metabolism.

Ortega F, Acerenza L.

FEBS J. 2011 Jul;278(14):2565-78. doi: 10.1111/j.1742-4658.2011.08184.x. Epub 2011 Jun 13.

6.

In silico strategy to rationally engineer metabolite production: A case study for threonine in Escherichia coli.

Rodríguez-Prados JC, de Atauri P, Maury J, Ortega F, Portais JC, Chassagnole C, Acerenza L, Lindley ND, Cascante M.

Biotechnol Bioeng. 2009 Jun 15;103(3):609-20. doi: 10.1002/bit.22271.

PMID:
19219914
7.

A hierarchical approach to cooperativity in macromolecular and self-assembling binding systems.

Garcés JL, Acerenza L, Mizraji E, Mas F.

J Biol Phys. 2008 Apr;34(1-2):213-35. doi: 10.1007/s10867-008-9116-x. Epub 2008 Oct 9.

8.

A strategy to calculate the patterns of nutrient consumption by microorganisms applying a two-level optimisation principle to reconstructed metabolic networks.

Ponce de León M, Cancela H, Acerenza L.

J Biol Phys. 2008 Apr;34(1-2):73-90. doi: 10.1007/s10867-008-9067-2. Epub 2008 May 14.

9.

Kinetic properties required for sustained or paradoxical control of metabolic fluxes under large changes in enzyme activities.

Ortega F, Cascante M, Acerenza L.

J Theor Biol. 2008 Jun 7;252(3):569-73. Epub 2007 Oct 22.

PMID:
18045618
10.

Modular metabolic control analysis of large responses.

Acerenza L, Ortega F.

FEBS J. 2007 Jan;274(1):188-201.

11.

On the origins of a crowded cytoplasm.

Acerenza L, Graña M.

J Mol Evol. 2006 Nov;63(5):583-90. Epub 2006 Sep 26.

PMID:
17009126
12.

Metabolic control analysis for large changes: extension to variable elasticity coefficients.

Acerenza L, Ortega F.

Syst Biol (Stevenage). 2006 Sep;153(5):323-6.

PMID:
16986308
13.
14.

Sensitivity analysis of metabolic cascades catalyzed by bifunctional enzymes.

Ortega F, Ehrenberg M, Acerenza L, Westerhoff HV, Mas F, Cascante M.

Mol Biol Rep. 2002;29(1-2):211-5.

PMID:
12241060
15.
16.

Product dependence and bifunctionality compromise the ultrasensitivity of signal transduction cascades.

Ortega F, Acerenza L, Westerhoff HV, Mas F, Cascante M.

Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1170-5.

17.
18.

Occurrence of paradoxical or sustained control by an enzyme when overexpressed: necessary conditions and experimental evidence with regard to hepatic glucokinase.

De Atauri P, Acerenza L, Kholodenko BN, De La Iglesia N, Guinovart JJ, Agius L, Cascante M.

Biochem J. 2001 May 1;355(Pt 3):787-93.

19.

Design of large metabolic responses. Constraints and sensitivity analysis.

Acerenza L.

J Theor Biol. 2000 Nov 21;207(2):265-82.

PMID:
11034833
20.

Optimal metabolic control design.

Ortega F, Acerenza L.

J Theor Biol. 1998 Apr 21;191(4):439-49.

PMID:
9705683
21.

Generalization of the double-modulation method for in situ determination of elasticities.

Acerenza L, Cornish-Bowden A.

Biochem J. 1997 Oct 1;327 ( Pt 1):217-24.

22.

Cooperativity: a unified view.

Acerenza L, Mizraji E.

Biochim Biophys Acta. 1997 Apr 25;1339(1):155-66.

PMID:
9165110
23.

How constrained is metabolic control?

Acerenza L.

J Theor Biol. 1996 Oct 7;182(3):277-83.

PMID:
8944159
24.
25.

Metabolic control design.

Acerenza L.

J Theor Biol. 1993 Nov 7;165(1):63-85.

PMID:
8264249
26.

A universal method for achieving increases in metabolite production.

Kacser H, Acerenza L.

Eur J Biochem. 1993 Sep 1;216(2):361-7.

28.

Enzyme-enzyme interactions and control analysis. 1. The case of non-additivity: monomer-oligomer associations.

Kacser H, Sauro HM, Acerenza L.

Eur J Biochem. 1990 Feb 14;187(3):481-91. Review.

29.

Control analysis of time-dependent metabolic systems.

Acerenza L, Sauro HM, Kacser H.

J Theor Biol. 1989 Apr 20;137(4):423-44.

PMID:
2626059
30.

Time delays in metabolic control systems.

Mizraji E, Acerenza L, Hernández J.

Biosystems. 1988;22(1):11-7.

PMID:
3191217
31.

Viscoelastic models for enzymes with multiple conformational states.

Mizraji E, Acerenza L, Lin J.

J Theor Biol. 1987 Nov 21;129(2):163-75.

PMID:
3455460

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