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J Pediatr Endocrinol Metab. 1998 Sep-Oct;11(5):653-6.

Serum leptin in obese patients with Laron syndrome before and during IGF-I treatment.

Author information

1
Endocrine & Diabetes Research Unit, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.

Abstract

Fifteen patients with primary GH resistance (Laron syndrome, LS) were studied before and during 6 months of daily replacement treatment with IGF-I. The main findings were that patients with LS and normal or high serum GH binding protein (GHBP) were less obese than those with a negative GHBP, and that serum leptin levels varied with body mass as in other types of obesity.

PMID:
9829217
DOI:
10.1515/jpem.1998.11.5.653
[Indexed for MEDLINE]

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