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Nurse Pract Forum. 1998 Jun;9(2):42-5.

Pathophysiology of diabetes mellitus.

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Veterans Affairs Puget Sound Health Care System, Seattle Division, WA 98108, USA.


The most common types of diabetes observed in a primary care practice are type 1, type 2, and gestational diabetes. Type 1 diabetes is an autoimmune disease characterized by total destruction of the pancreatic beta cells, whereas insulin resistance, impaired insulin secretion, and inappropriate hepatic glucose secretion characterize type 2 diabetes. Gestational diabetes is similar to type 2 diabetes, but is first diagnosed during pregnancy.

[Indexed for MEDLINE]

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