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J Am Acad Dermatol. 1994 Jul;31(1):1-19; quiz 20-2.

Acanthosis nigricans.

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1
New Jersey Medical School, Newark 07103-2714.

Abstract

Acanthosis nigricans is a mucocutaneous eruption that occurs in a strikingly exuberant form as a marker for a highly malignant and rapidly fatal internal cancer. Recently, it has been recognized that acanthosis nigricans may also be a relatively common marker for increased long-term risk of the less dramatic but potentially serious systemic disorders associated with insulin resistance and compensatory increased insulin secretion.

PMID:
8021347
[Indexed for MEDLINE]

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