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Gynecol Oncol. 2006 Feb;100(2):433-6. Epub 2005 Oct 14.

A case of monophasic synovial sarcoma presenting as a vulvar mass.

Author information

1
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030, USA. dambani@bcm.tmc.edu

Abstract

BACKGROUND:

Synovial sarcoma is the fourth most commonly occurring sarcoma, accounting for 8-10% of all sarcomas. They arise from unknown pleuripotent stem cells that are capable of differentiating into mesenchymal and/or epithelial structures. Synovial sarcoma is characterized by specific chromosomal translocation t (X; 18)(p11, q11).

CASE:

We report the first case of monophasic synovial sarcoma arising in soft tissues of the vulva in a 33-year-old female. Complete excision of the mass was possible with tumor-free margins.

CONCLUSION:

Only four previous cases of biphasic synovial sarcoma arising in the vulva have been reported. The finding of the SYT-SSX2 translocation is generally associated with a better prognosis, besides tumor negative margins after excision offer the possibility of a better outlook for this patient.

PMID:
16226798
DOI:
10.1016/j.ygyno.2005.09.013
[Indexed for MEDLINE]

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