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Items: 20


Glutamate dehydrogenase: Structure of a hyperinsulinism mutant, corrections to the atomic model, and insights into a regulatory site.

Nassar OM, Li C, Stanley CA, Pettitt BM, Smith TJ.

Proteins. 2019 Jan;87(1):41-50. doi: 10.1002/prot.25620. Epub 2018 Nov 18.


Cellular production of a counterfeit viral protein confers immunity to infection by a related virus.

Warner BE, Ballinger MJ, Yerramsetty P, Reed J, Taylor DJ, Smith TJ, Bruenn JA.

PeerJ. 2018 Sep 28;6:e5679. doi: 10.7717/peerj.5679. eCollection 2018.


Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition.

Dunne M, Denyes JM, Arndt H, Loessner MJ, Leiman PG, Klumpp J.

Structure. 2018 Dec 4;26(12):1573-1582.e4. doi: 10.1016/j.str.2018.07.017. Epub 2018 Sep 20.


Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor.

Nelson CA, Wilen CB, Dai YN, Orchard RC, Kim AS, Stegeman RA, Hsieh LL, Smith TJ, Virgin HW, Fremont DH.

Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):E9201-E9210. doi: 10.1073/pnas.1805797115. Epub 2018 Sep 7.


Structural Plasticity of Neurexin 1╬▒: Implications for its Role as Synaptic Organizer.

Liu J, Misra A, Reddy MVVVS, White MA, Ren G, Rudenko G.

J Mol Biol. 2018 Oct 19;430(21):4325-4343. doi: 10.1016/j.jmb.2018.08.026. Epub 2018 Sep 5.


FerA is a Membrane-Associating Four-Helix Bundle Domain in the Ferlin Family of Membrane-Fusion Proteins.

Harsini FM, Chebrolu S, Fuson KL, White MA, Rice AM, Sutton RB.

Sci Rep. 2018 Jul 19;8(1):10949. doi: 10.1038/s41598-018-29184-1.


Molecular switch-like regulation enables global subunit coordination in a viral ring ATPase.

Tafoya S, Liu S, Castillo JP, Atz R, Morais MC, Grimes S, Jardine PJ, Bustamante C.

Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):7961-7966. doi: 10.1073/pnas.1802736115. Epub 2018 Jul 16.


Correction to: Fungal Secretome Analysis Via PepSAVI-MS: Identification of the Bioactive Peptide KP4 from Ustilago maydis.

Kirkpatrick CL, Parsley NC, Bartges TE, Cooke ME, Evans WS, Heil LR, Smith TJ, Hicks LM.

J Am Soc Mass Spectrom. 2018 Sep;29(9):1940. doi: 10.1007/s13361-018-2016-9.


Evolution on the Biophysical Fitness Landscape of an RNA Virus.

Rotem A, Serohijos AWR, Chang CB, Wolfe JT, Fischer AE, Mehoke TS, Zhang H, Tao Y, Lloyd Ung W, Choi JM, Rodrigues JV, Kolawole AO, Koehler SA, Wu S, Thielen PM, Cui N, Demirev PA, Giacobbi NS, Julian TR, Schwab K, Lin JS, Smith TJ, Pipas JM, Wobus CE, Feldman AB, Weitz DA, Shakhnovich EI.

Mol Biol Evol. 2018 Oct 1;35(10):2390-2400. doi: 10.1093/molbev/msy131.


PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance.

Wen JJ, Yin YW, Garg NJ.

PLoS Pathog. 2018 May 31;14(5):e1007065. doi: 10.1371/journal.ppat.1007065. eCollection 2018 May.


Ehrlichia chaffeensis TRP120 nucleomodulin binds DNA with disordered tandem repeat domain.

Klema VJ, Sepuru KM, F├╝llbrunn N, Farris TR, Dunphy PS, McBride JW, Rajarathnam K, Choi KH.

PLoS One. 2018 Apr 11;13(4):e0194891. doi: 10.1371/journal.pone.0194891. eCollection 2018.


Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor.

Wild CT, Miszkiel JM, Wold EA, Soto CA, Ding C, Hartley RM, White MA, Anastasio NC, Cunningham KA, Zhou J.

J Med Chem. 2019 Jan 10;62(1):288-305. doi: 10.1021/acs.jmedchem.8b00401. Epub 2018 Apr 13.


Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design.

Lin J, Zhou D, Steitz TA, Polikanov YS, Gagnon MG.

Annu Rev Biochem. 2018 Jun 20;87:451-478. doi: 10.1146/annurev-biochem-062917-011942. Epub 2018 Mar 23. Review.


Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads.

Ding Y, Li D, Ding C, Wang P, Liu Z, Wold EA, Ye N, Chen H, White MA, Shen Q, Zhou J.

J Med Chem. 2018 Apr 12;61(7):2737-2752. doi: 10.1021/acs.jmedchem.7b01514. Epub 2018 Mar 20.


Contractile injection systems of bacteriophages and related systems.

Taylor NMI, van Raaij MJ, Leiman PG.

Mol Microbiol. 2018 Apr;108(1):6-15. doi: 10.1111/mmi.13921. Epub 2018 Feb 26. Review.


Fungal Secretome Analysis via PepSAVI-MS: Identification of the Bioactive Peptide KP4 from Ustilago maydis.

Kirkpatrick CL, Parsley NC, Bartges TE, Cooke ME, Evans WS, Heil LR, Smith TJ, Hicks LM.

J Am Soc Mass Spectrom. 2018 May;29(5):859-865. doi: 10.1007/s13361-017-1880-z. Epub 2018 Feb 5. Erratum in: J Am Soc Mass Spectrom. 2018 Sep;29(9):1940.


Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic.

Ali SR, Liu Z, Nenov MN, Folorunso O, Singh A, Scala F, Chen H, James TF, Alshammari M, Panova-Elektronova NI, White MA, Zhou J, Laezza F.

ACS Chem Neurosci. 2018 May 16;9(5):976-987. doi: 10.1021/acschemneuro.7b00399. Epub 2018 Feb 6.


Stretching the arms of the type VI secretion sheath protein.

Leiman PG.

EMBO Rep. 2018 Feb;19(2):191-193. doi: 10.15252/embr.201745627. Epub 2018 Jan 22. No abstract available.


Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells.

Zhou W, Woodson M, Neupane B, Bai F, Sherman MB, Choi KH, Neelakanta G, Sultana H.

PLoS Pathog. 2018 Jan 4;14(1):e1006764. doi: 10.1371/journal.ppat.1006764. eCollection 2018 Jan.


Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice.

Neelakantan H, Vance V, Wetzel MD, Wang HL, McHardy SF, Finnerty CC, Hommel JD, Watowich SJ.

Biochem Pharmacol. 2018 Jan;147:141-152. doi: 10.1016/j.bcp.2017.11.007. Epub 2017 Nov 15.

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