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Items: 19

1.

Conformational States of Exchange Protein Directly Activated by cAMP (EPAC1) Revealed by Ensemble Modeling and Integrative Structural Biology.

White MA, Tsalkova T, Mei FC, Cheng X.

Cells. 2019 Dec 21;9(1). pii: E35. doi: 10.3390/cells9010035.

2.

Structural basis for ribosome recycling by RRF and tRNA.

Zhou D, Tanzawa T, Lin J, Gagnon MG.

Nat Struct Mol Biol. 2020 Jan;27(1):25-32. doi: 10.1038/s41594-019-0350-7. Epub 2019 Dec 23.

PMID:
31873307
3.

Modeling the Architecture of Depolymerase-Containing Receptor Binding Proteins in Klebsiella Phages.

Latka A, Leiman PG, Drulis-Kawa Z, Briers Y.

Front Microbiol. 2019 Nov 15;10:2649. doi: 10.3389/fmicb.2019.02649. eCollection 2019.

4.

Allosteric discrimination at the NADH/ADP regulatory site of glutamate dehydrogenase.

Nassar OM, Wong KY, Lynch GC, Smith TJ, Pettitt BM.

Protein Sci. 2019 Dec;28(12):2080-2088. doi: 10.1002/pro.3748. Epub 2019 Nov 1.

PMID:
31610054
5.

Dissecting the Antenna in Human Glutamate Dehydrogenase: Understanding Its Role in Subunit Communication and Allosteric Regulation.

Hoffpauir ZA, Sherman E, Smith TJ.

Biochemistry. 2019 Oct 15;58(41):4195-4206. doi: 10.1021/acs.biochem.9b00722. Epub 2019 Oct 7.

PMID:
31577135
6.

Differential modulation of energy landscapes of cyclic AMP receptor protein (CRP) as a regulatory mechanism for class II CRP-dependent promoters.

Evangelista W, Dong A, White MA, Li J, Lee JC.

J Biol Chem. 2019 Oct 18;294(42):15544-15556. doi: 10.1074/jbc.RA119.009151. Epub 2019 Sep 6.

PMID:
31492755
7.

[The new system of remuneration of labor in budget health care: analysis of practice and problems of implementation].

Doljenkova YV, Polevaya MV, Rudenko GG.

Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med. 2019 Jul;27(4):452-458. doi: 10.32687/0869-866X-2019-27-4-452-458. Russian.

PMID:
31465665
8.

Target highlights in CASP13: Experimental target structures through the eyes of their authors.

Lepore R, Kryshtafovych A, Alahuhta M, Veraszto HA, Bomble YJ, Bufton JC, Bullock AN, Caba C, Cao H, Davies OR, Desfosses A, Dunne M, Fidelis K, Goulding CW, Gurusaran M, Gutsche I, Harding CJ, Hartmann MD, Hayes CS, Joachimiak A, Leiman PG, Loppnau P, Lovering AL, Lunin VV, Michalska K, Mir-Sanchis I, Mitra AK, Moult J, Phillips GN Jr, Pinkas DM, Rice PA, Tong Y, Topf M, Walton JD, Schwede T.

Proteins. 2019 Dec;87(12):1037-1057. doi: 10.1002/prot.25805. Epub 2019 Sep 9.

9.

Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5-b]pyridine-7,3'-indoline]-2',5(3H)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection.

Xu J, Xie X, Ye N, Zou J, Chen H, White MA, Shi PY, Zhou J.

J Med Chem. 2019 Sep 12;62(17):7941-7960. doi: 10.1021/acs.jmedchem.9b00698. Epub 2019 Aug 23.

PMID:
31403780
10.

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion.

Sherman MB, Williams AN, Smith HQ, Nelson C, Wilen CB, Fremont DH, Virgin HW, Smith TJ.

J Virol. 2019 Sep 12;93(19). pii: e00970-19. doi: 10.1128/JVI.00970-19. Print 2019 Oct 1.

PMID:
31341042
11.

Structure and Function of the Branched Receptor-Binding Complex of Bacteriophage CBA120.

Plattner M, Shneider MM, Arbatsky NP, Shashkov AS, Chizhov AO, Nazarov S, Prokhorov NS, Taylor NMI, Buth SA, Gambino M, Gencay YE, Br√łndsted L, Kutter EM, Knirel YA, Leiman PG.

J Mol Biol. 2019 Sep 6;431(19):3718-3739. doi: 10.1016/j.jmb.2019.07.022. Epub 2019 Jul 17.

PMID:
31325442
12.
13.

Networked Communication between Polymerase and Exonuclease Active Sites in Human Mitochondrial DNA Polymerase.

Sowers ML, Anderson APP, Wrabl JO, Yin YW.

J Am Chem Soc. 2019 Jul 10;141(27):10821-10829. doi: 10.1021/jacs.9b04655. Epub 2019 Jun 28.

PMID:
31251605
14.

Editorial overview: Synapses: bridging the gap between their structure and function.

Rudenko G, Takahashi H.

Curr Opin Struct Biol. 2019 Feb;54:iii-vii. doi: 10.1016/j.sbi.2019.05.020. No abstract available.

PMID:
31235062
15.

The Dynamic Capsid Structures of the Noroviruses.

Smith HQ, Smith TJ.

Viruses. 2019 Mar 8;11(3). pii: E235. doi: 10.3390/v11030235. Review.

16.

Neurexins - versatile molecular platforms in the synaptic cleft.

Rudenko G.

Curr Opin Struct Biol. 2019 Feb;54:112-121. doi: 10.1016/j.sbi.2019.01.009. Epub 2019 Mar 2. Review.

PMID:
30831539
17.

Glutamate dehydrogenase: Structure of a hyperinsulinism mutant, corrections to the atomic model, and insights into a regulatory site.

Nassar OM, Li C, Stanley CA, Pettitt BM, Smith TJ.

Proteins. 2019 Jan;87(1):41-50. doi: 10.1002/prot.25620. Epub 2018 Nov 18.

18.

Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor.

Wild CT, Miszkiel JM, Wold EA, Soto CA, Ding C, Hartley RM, White MA, Anastasio NC, Cunningham KA, Zhou J.

J Med Chem. 2019 Jan 10;62(1):288-305. doi: 10.1021/acs.jmedchem.8b00401. Epub 2018 Apr 13.

19.

Glutamate Dehydrogenase, a Complex Enzyme at a Crucial Metabolic Branch Point.

Smith HQ, Li C, Stanley CA, Smith TJ.

Neurochem Res. 2019 Jan;44(1):117-132. doi: 10.1007/s11064-017-2428-0. Epub 2017 Oct 27. Review.

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