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Items: 20


The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS.

Hoem G, Bowitz Larsen K, Øvervatn A, Brech A, Lamark T, Sjøttem E, Johansen T.

Front Genet. 2019 Mar 28;10:249. doi: 10.3389/fgene.2019.00249. eCollection 2019.


FKBP8 recruits LC3A to mediate Parkin-independent mitophagy.

Bhujabal Z, Birgisdottir ÅB, Sjøttem E, Brenne HB, Øvervatn A, Habisov S, Kirkin V, Lamark T, Johansen T.

EMBO Rep. 2017 Jun;18(6):947-961. doi: 10.15252/embr.201643147. Epub 2017 Apr 5.


FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy.

Olsvik HL, Lamark T, Takagi K, Larsen KB, Evjen G, Øvervatn A, Mizushima T, Johansen T.

J Biol Chem. 2015 Dec 4;290(49):29361-74. doi: 10.1074/jbc.M115.686915. Epub 2015 Oct 14.


ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.

Alemu EA, Lamark T, Torgersen KM, Birgisdottir AB, Larsen KB, Jain A, Olsvik H, Øvervatn A, Kirkin V, Johansen T.

J Biol Chem. 2012 Nov 16;287(47):39275-90. doi: 10.1074/jbc.M112.378109. Epub 2012 Oct 5.


A reporter cell system to monitor autophagy based on p62/SQSTM1.

Larsen KB, Lamark T, Øvervatn A, Harneshaug I, Johansen T, Bjørkøy G.

Autophagy. 2010 Aug;6(6):784-93. Epub 2010 Aug 28.


p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.

Jain A, Lamark T, Sjøttem E, Larsen KB, Awuh JA, Øvervatn A, McMahon M, Hayes JD, Johansen T.

J Biol Chem. 2010 Jul 16;285(29):22576-91. doi: 10.1074/jbc.M110.118976. Epub 2010 May 7.


p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy.

Clausen TH, Lamark T, Isakson P, Finley K, Larsen KB, Brech A, Øvervatn A, Stenmark H, Bjørkøy G, Simonsen A, Johansen T.

Autophagy. 2010 Apr;6(3):330-44. Epub 2010 Apr 11.


FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport.

Pankiv S, Alemu EA, Brech A, Bruun JA, Lamark T, Overvatn A, Bjørkøy G, Johansen T.

J Cell Biol. 2010 Jan 25;188(2):253-69. doi: 10.1083/jcb.200907015.


Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinated proteins to promyelocytic leukemia bodies.

Pankiv S, Lamark T, Bruun JA, Øvervatn A, Bjørkøy G, Johansen T.

J Biol Chem. 2010 Feb 19;285(8):5941-53. doi: 10.1074/jbc.M109.039925. Epub 2009 Dec 15.


A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.

Kirkin V, Lamark T, Sou YS, Bjørkøy G, Nunn JL, Bruun JA, Shvets E, McEwan DG, Clausen TH, Wild P, Bilusic I, Theurillat JP, Øvervatn A, Ishii T, Elazar Z, Komatsu M, Dikic I, Johansen T.

Mol Cell. 2009 Feb 27;33(4):505-16. doi: 10.1016/j.molcel.2009.01.020.


Monitoring autophagic degradation of p62/SQSTM1.

Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T.

Methods Enzymol. 2009;452:181-97. doi: 10.1016/S0076-6879(08)03612-4.


p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.

Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Øvervatn A, Bjørkøy G, Johansen T.

J Biol Chem. 2007 Aug 17;282(33):24131-45. Epub 2007 Jun 19.


p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death.

Bjørkøy G, Lamark T, Brech A, Outzen H, Perander M, Overvatn A, Stenmark H, Johansen T.

J Cell Biol. 2005 Nov 21;171(4):603-14. Epub 2005 Nov 14.


Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins.

Lamark T, Perander M, Outzen H, Kristiansen K, Øvervatn A, Michaelsen E, Bjørkøy G, Johansen T.

J Biol Chem. 2003 Sep 5;278(36):34568-81. Epub 2003 Jun 17.


Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C.

Bjørkøy G, Overvatn A, Diaz-Meco MT, Moscat J, Johansen T.

J Biol Chem. 1995 Sep 8;270(36):21299-306.


The effect of beta-D-xylosides on the proliferation and proteoglycan biosynthesis of monoblastic U-937 cells.

Kolset SO, Sakurai K, Ivhed I, Overvatn A, Suzuki S.

Biochem J. 1990 Feb 1;265(3):637-45.


Differentiation-associated changes in the expression of chondroitin sulfate proteoglycan in induced U-937 cells.

Kolset SO, Ivhed I, Overvatn A, Nilsson K.

Cancer Res. 1988 Nov 1;48(21):6103-8.

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