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Items: 35

1.

Enhanced detection of circulating tumor DNA by fragment size analysis.

Mouliere F, Chandrananda D, Piskorz AM, Moore EK, Morris J, Ahlborn LB, Mair R, Goranova T, Marass F, Heider K, Wan JCM, Supernat A, Hudecova I, Gounaris I, Ros S, Jimenez-Linan M, Garcia-Corbacho J, Patel K, Østrup O, Murphy S, Eldridge MD, Gale D, Stewart GD, Burge J, Cooper WN, van der Heijden MS, Massie CE, Watts C, Corrie P, Pacey S, Brindle KM, Baird RD, Mau-Sørensen M, Parkinson CA, Smith CG, Brenton JD, Rosenfeld N.

Sci Transl Med. 2018 Nov 7;10(466). pii: eaat4921. doi: 10.1126/scitranslmed.aat4921.

PMID:
30404863
2.

Maternally inherited rRNA triggers de novo nucleolus formation in porcine embryos.

Morovic M, Østrup O, Strejcek F, Benc M, Murin M, Jedlickova K, Bartkova A, Lucas-Hahn A, Pendovski L, Laurincik J.

Zygote. 2018 Oct 12:1-8. doi: 10.1017/S0967199418000400. [Epub ahead of print]

PMID:
30311594
3.

Copenhagen Prospective Personalized Oncology (CoPPO) - Clinical utility of using molecular profiling to select patients to phase 1 trials.

Tuxen IV, Rohrberg KS, Østrup O, Ahlborn LB, Schmidt AY, Spanggaard I, Hasselby JP, Santoni-Rugiu E, Yde CW, Mau-Soerensen M, Nielsen FC, Lassen U.

Clin Cancer Res. 2018 Oct 1. pii: clincanres.1780.2018. doi: 10.1158/1078-0432.CCR-18-1780. [Epub ahead of print]

PMID:
30274980
4.

Genomic alterations accompanying tumour evolution in colorectal cancer: tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing.

Mogensen MB, Rossing M, Østrup O, Larsen PN, Heiberg Engel PJ, Jørgensen LN, Hogdall EV, Eriksen J, Ibsen P, Jess P, Grauslund M, Nielsen HJ, Nielsen FC, Vainer B, Osterlind K.

BMC Cancer. 2018 Jul 20;18(1):752. doi: 10.1186/s12885-018-4639-4.

5.

Importance of Comprehensive Molecular Profiling for Clinical Outcome in Children With Recurrent Cancer.

Østrup O, Nysom K, Scheie D, Schmidt AY, Mathiasen R, Hjalgrim LL, Olsen TE, Skjøth-Rasmussen J, Henriksen BM, Nielsen FC, Wehner PS, Schrøder H, Sehested AM, Rechnitzer C, Rossing M.

Front Pediatr. 2018 Apr 20;6:114. doi: 10.3389/fped.2018.00114. eCollection 2018.

6.

Acute Haemarthrosis in the Haemophilia A Rat Generates a Local and Systemic Proinflammatory Response.

Lövgren KM, Christensen KR, Majewski W, Østrup O, Skov S, Wiinberg B.

Thromb Haemost. 2017 Nov;117(11):2092-2104. doi: 10.1160/TH17-03-0149. Epub 2017 Nov 30.

PMID:
29202211
7.

Molecular subtyping of breast cancer improves identification of both high and low risk patients.

Rossing M, Østrup O, Majewski WW, Kinalis S, Jensen MB, Knoop A, Kroman N, Talman ML, Hansen TVO, Ejlertsen B, Nielsen FC.

Acta Oncol. 2018 Jan;57(1):58-66. doi: 10.1080/0284186X.2017.1398416. Epub 2017 Nov 22.

PMID:
29164972
8.

Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases.

Østrup O, Dagenborg VJ, Rødland EA, Skarpeteig V, Silwal-Pandit L, Grzyb K, Berstad AE, Fretland ÅA, Mælandsmo GM, Børresen-Dale AL, Ree AH, Edwin B, Nygaard V, Flatmark K.

Oncotarget. 2017 Jul 18;8(44):76290-76304. doi: 10.18632/oncotarget.19350. eCollection 2017 Sep 29.

9.

Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate.

Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA, Hagene KT, Aas E, Lurås H, Johnsen-Soriano S, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Mælandsmo GM, Flatmark K.

ESMO Open. 2017 May 2;2(2):e000158. doi: 10.1136/esmoopen-2017-000158. eCollection 2017.

10.

Application of whole-exome sequencing to direct the specific functional testing and diagnosis of rare inherited bleeding disorders in patients from the Öresund Region, Scandinavia.

Leinøe E, Zetterberg E, Kinalis S, Østrup O, Kampmann P, Norström E, Andersson N, Klintman J, Qvortrup K, Nielsen FC, Rossing M.

Br J Haematol. 2017 Oct;179(2):308-322. doi: 10.1111/bjh.14863. Epub 2017 Jul 27.

11.

Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo.

Genster N, Østrup O, Schjalm C, Eirik Mollnes T, Cowland JB, Garred P.

Sci Rep. 2017 Jun 20;7(1):3852. doi: 10.1038/s41598-017-04121-w.

12.

Genomic diagnostics leading to the identification of a TFG-ROS1 fusion in a child with possible atypical meningioma.

Rossing M, Yde CW, Sehested A, Østrup O, Scheie D, Dangouloff-Ros V, Geoerger B, Vassal G, Nysom K.

Cancer Genet. 2017 Apr;212-213:32-37. doi: 10.1016/j.cancergen.2017.03.005. Epub 2017 Mar 22.

13.

Detection of copy number alterations in cell-free tumor DNA from plasma.

Østrup O, Ahlborn LB, Lassen U, Mau-Sørensen M, Nielsen FC.

BBA Clin. 2017 Apr 4;7:120-126. doi: 10.1016/j.bbacli.2017.03.006. eCollection 2017 Jun.

14.

Metabolic state defines the response of rabbit ovarian cells to leptin.

Harrath AH, Østrup O, Rafay J, Koničková Florkovičová I, Laurincik J, Sirotkin AV.

Reprod Biol. 2017 Mar;17(1):19-24. doi: 10.1016/j.repbio.2016.11.002. Epub 2016 Nov 25.

PMID:
27894742
15.

A new NFIA:RAF1 fusion activating the MAPK pathway in pilocytic astrocytoma.

Yde CW, Sehested A, Mateu-Regué À, Østrup O, Scheie D, Nysom K, Nielsen FC, Rossing M.

Cancer Genet. 2016 Oct;209(10):440-444. doi: 10.1016/j.cancergen.2016.09.002. Epub 2016 Sep 16.

16.

Analysis of nucleolar morphology and protein localization as an indicator of nuclear reprogramming.

Østrup O, Pedersen HS, Holm HM, Hyttel P.

Methods Mol Biol. 2015;1222:161-74. doi: 10.1007/978-1-4939-1594-1_12.

PMID:
25287345
17.

The specific alteration of histone methylation profiles by DZNep during early zebrafish development.

Ostrup O, Reiner AH, Aleström P, Collas P.

Biochim Biophys Acta. 2014 Nov;1839(11):1307-15. doi: 10.1016/j.bbagrm.2014.09.013. Epub 2014 Sep 28.

PMID:
25260724
18.

Long-term effect on in vitro cloning efficiency after treatment of somatic cells with Xenopus egg extract in the pig.

Liu Y, Ostrup O, Li R, Li J, Vajta G, Kragh PM, Schmidt M, Purup S, Hyttel P, Klærke D, Callesen H.

Reprod Fertil Dev. 2014 Aug;26(7):1017-31. doi: 10.1071/RD13147.

PMID:
25145414
19.

Normalization of RNA-sequencing data from samples with varying mRNA levels.

Aanes H, Winata C, Moen LF, Østrup O, Mathavan S, Collas P, Rognes T, Aleström P.

PLoS One. 2014 Feb 25;9(2):e89158. doi: 10.1371/journal.pone.0089158. eCollection 2014.

20.

Differential transcript isoform usage pre- and post-zygotic genome activation in zebrafish.

Aanes H, Østrup O, Andersen IS, Moen LF, Mathavan S, Collas P, Alestrom P.

BMC Genomics. 2013 May 15;14:331. doi: 10.1186/1471-2164-14-331.

21.

RNA profiles of porcine embryos during genome activation reveal complex metabolic switch sensitive to in vitro conditions.

Østrup O, Olbricht G, Østrup E, Hyttel P, Collas P, Cabot R.

PLoS One. 2013 Apr 29;8(4):e61547. doi: 10.1371/journal.pone.0061547. Print 2013.

22.

Epigenetic marking of the zebrafish developmental program.

Andersen IS, Lindeman LC, Reiner AH, Østrup O, Aanes H, Aleström P, Collas P.

Curr Top Dev Biol. 2013;104:85-112. doi: 10.1016/B978-0-12-416027-9.00003-6. Review.

PMID:
23587239
23.

Chromatin-linked determinants of zygotic genome activation.

Østrup O, Andersen IS, Collas P.

Cell Mol Life Sci. 2013 Apr;70(8):1425-37. doi: 10.1007/s00018-012-1143-x. Epub 2012 Sep 11. Review.

PMID:
22965566
24.

RNA polymerase II transcriptional silencing in growing and fully grown germinal vesicle oocytes isolated from gonadotropin-stimulated and non-stimulated gilts.

Barnetova I, Morovic M, Strejcek F, Østrup O, Hyttel P, Niemann H, Laurincik J, Fulka J Jr, Fulka H.

Mol Reprod Dev. 2012 Oct;79(10):697-708. doi: 10.1002/mrd.22077. Epub 2012 Aug 15.

PMID:
22847943
25.

Early aberrations in chromatin dynamics in embryos produced under in vitro conditions.

Deshmukh RS, Østrup O, Strejcek F, Vejlsted M, Lucas-Hahn A, Petersen B, Li J, Callesen H, Niemann H, Hyttel P.

Cell Reprogram. 2012 Jun;14(3):225-34. doi: 10.1089/cell.2011.0069. Epub 2012 Apr 2.

26.

Epigenetic complexity during the zebrafish mid-blastula transition.

Andersen IS, Ostrup O, Lindeman LC, Aanes H, Reiner AH, Mathavan S, Aleström P, Collas P.

Biochem Biophys Res Commun. 2012 Jan 27;417(4):1139-44. doi: 10.1016/j.bbrc.2011.12.077. Epub 2011 Dec 22.

PMID:
22209792
27.

Prepatterning of developmental gene expression by modified histones before zygotic genome activation.

Lindeman LC, Andersen IS, Reiner AH, Li N, Aanes H, Østrup O, Winata C, Mathavan S, Müller F, Aleström P, Collas P.

Dev Cell. 2011 Dec 13;21(6):993-1004. doi: 10.1016/j.devcel.2011.10.008. Epub 2011 Dec 1.

28.

Embryo-maternal communication: signalling before and during placentation in cattle and pig.

Ostrup E, Hyttel P, Ostrup O.

Reprod Fertil Dev. 2011;23(8):964-75. doi: 10.1071/RD11140. Review.

PMID:
22127002
29.

Cell colony formation induced by Xenopus egg extract as a marker for improvement of cloned blastocyst formation in the pig.

Liu Y, Østrup O, Li J, Vajta G, Kragh PM, Purup S, Callesen H.

Cell Reprogram. 2011 Dec;13(6):521-6. doi: 10.1089/cell.2011.0029. Epub 2011 Nov 1.

PMID:
22043808
30.

Remodeling of ribosomal genes in somatic cells by Xenopus egg extract.

Østrup O, Hyttel P, Klærke DA, Collas P.

Biochem Biophys Res Commun. 2011 Sep 2;412(3):487-93. doi: 10.1016/j.bbrc.2011.07.128. Epub 2011 Aug 6.

PMID:
21843509
31.

Role of ooplasm in nuclear and nucleolar remodeling of intergeneric somatic cell nuclear transfer embryos during the first cell cycle.

Østrup O, Strejcek F, Petrovicova I, Lucas-Hahn A, Morovic M, Lemme E, Petersen B, Laurincikova N, Niemann H, Laurincik J, Hyttel P.

Cell Reprogram. 2011 Apr;13(2):145-55. doi: 10.1089/cell.2010.0061.

PMID:
21473691
32.

Increased blastocyst formation of cloned porcine embryos produced with donor cells pre-treated with Xenopus egg extract and/or digitonin.

Liu Y, Ostrup O, Li J, Vajta G, Lin L, Kragh PM, Purup S, Hyttel P, Callesen H.

Zygote. 2012 Feb;20(1):61-6. doi: 10.1017/S096719941000064X. Epub 2011 Feb 8.

PMID:
21303584
33.

Changes of DNA methylation level and spatial arrangement of primordial germ cells in embryonic day 15 to embryonic day 28 pig embryos.

Hyldig SM, Ostrup O, Vejlsted M, Thomsen PD.

Biol Reprod. 2011 Jun;84(6):1087-93. doi: 10.1095/biolreprod.110.086082. Epub 2011 Feb 3.

PMID:
21293033
34.

DNA methylation in porcine preimplantation embryos developed in vivo and produced by in vitro fertilization, parthenogenetic activation and somatic cell nuclear transfer.

Deshmukh RS, Østrup O, Østrup E, Vejlsted M, Niemann H, Lucas-Hahn A, Petersen B, Li J, Callesen H, Hyttel P.

Epigenetics. 2011 Feb;6(2):177-87. Epub 2011 Feb 1.

PMID:
20935454
35.

Nuclear and nucleolar reprogramming during the first cell cycle in bovine nuclear transfer embryos.

Østrup O, Petrovicova I, Strejcek F, Morovic M, Lucas-Hahn A, Lemme E, Petersen B, Niemann H, Laurincik J, Maddox-Hyttel P.

Cloning Stem Cells. 2009 Sep;11(3):367-75. doi: 10.1089/clo.2008.0076.

PMID:
19594386

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