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Items: 47

1.

Acoustic formation of multicellular tumor spheroids enabling on-chip functional and structural imaging.

Olofsson K, Carannante V, Ohlin M, Frisk T, Kushiro K, Takai M, Lundqvist A, Önfelt B, Wiklund M.

Lab Chip. 2018 Aug 7;18(16):2466-2476. doi: 10.1039/c8lc00537k.

PMID:
30033460
2.

Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells.

Srpan K, Ambrose A, Karampatzakis A, Saeed M, Cartwright ANR, Guldevall K, De Matos GDSC, Önfelt B, Davis DM.

J Cell Biol. 2018 Jul 2. pii: jcb.201712085. doi: 10.1083/jcb.201712085. [Epub ahead of print]

PMID:
29967280
3.

161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS.

Sarhan D, Brandt L, Felices M, Guldevall K, Lenvik T, Hinderlie P, Curtsinger J, Warlick E, Spellman SR, Blazar BR, Weisdorf DJ, Cooley S, Vallera DA, Önfelt B, Miller JS.

Blood Adv. 2018 Jun 26;2(12):1459-1469. doi: 10.1182/bloodadvances.2017012369.

4.

Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors.

Oei VYS, Siernicka M, Graczyk-Jarzynka A, Hoel HJ, Yang W, Palacios D, Almåsbak H, Bajor M, Clement D, Brandt L, Önfelt B, Goodridge J, Winiarska M, Zagozdzon R, Olweus J, Kyte JA, Malmberg KJ.

Cancer Immunol Res. 2018 Apr;6(4):467-480. doi: 10.1158/2326-6066.CIR-17-0207. Epub 2018 Feb 19.

PMID:
29459477
5.

Risk Factors for Severe Acute Graft-versus-Host Disease in Donor Graft Composition.

Stikvoort A, Gaballa A, Solders M, Nederlof I, Önfelt B, Sundberg B, Remberger M, Sundin M, Mattsson J, Uhlin M.

Biol Blood Marrow Transplant. 2018 Mar;24(3):467-477. doi: 10.1016/j.bbmt.2017.11.026. Epub 2017 Nov 29.

PMID:
29197674
6.

Laboratory cryo x-ray microscopy for 3D cell imaging.

Fogelqvist E, Kördel M, Carannante V, Önfelt B, Hertz HM.

Sci Rep. 2017 Oct 18;7(1):13433. doi: 10.1038/s41598-017-13538-2.

7.

NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing.

Hsu HT, Mace EM, Carisey AF, Viswanath DI, Christakou AE, Wiklund M, Önfelt B, Orange JS.

J Cell Biol. 2016 Dec 19;215(6):875-889. Epub 2016 Nov 30.

8.

Microwell-Based Live Cell Imaging of NK Cell Dynamics to Assess Heterogeneity in Motility and Cytotoxic Response.

Vanherberghen B, Frisk T, Forslund E, Olofsson PE, Guldevall K, Önfelt B.

Methods Mol Biol. 2016;1441:87-106. doi: 10.1007/978-1-4939-3684-7_8.

PMID:
27177659
9.

Microchip Screening Platform for Single Cell Assessment of NK Cell Cytotoxicity.

Guldevall K, Brandt L, Forslund E, Olofsson K, Frisk TW, Olofsson PE, Gustafsson K, Manneberg O, Vanherberghen B, Brismar H, Kärre K, Uhlin M, Önfelt B.

Front Immunol. 2016 Apr 5;7:119. doi: 10.3389/fimmu.2016.00119. eCollection 2016.

10.

Microchip-Based Single-Cell Imaging Reveals That CD56dimCD57-KIR-NKG2A+ NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56dimCD57-KIR-NKG2A- NK Cells.

Forslund E, Sohlberg E, Enqvist M, Olofsson PE, Malmberg KJ, Önfelt B.

J Immunol. 2015 Oct 1;195(7):3374-81. doi: 10.4049/jimmunol.1500171. Epub 2015 Aug 28.

11.

Newtonian cell interactions shape natural killer cell education.

Goodridge JP, Önfelt B, Malmberg KJ.

Immunol Rev. 2015 Sep;267(1):197-213. doi: 10.1111/imr.12325. Review.

12.

Ultrasonic three-dimensional on-chip cell culture for dynamic studies of tumor immune surveillance by natural killer cells.

Christakou AE, Ohlin M, Önfelt B, Wiklund M.

Lab Chip. 2015 Aug 7;15(15):3222-31. doi: 10.1039/c5lc00436e.

PMID:
26126574
13.

Single-Cell Characterization of in vitro Migration and Interaction Dynamics of T Cells Expanded with IL-2 and IL-7.

Tauriainen J, Gustafsson K, Göthlin M, Gertow J, Buggert M, Frisk TW, Karlsson AC, Uhlin M, Önfelt B.

Front Immunol. 2015 Apr 28;6:196. doi: 10.3389/fimmu.2015.00196. eCollection 2015.

14.

Coordinated expression of DNAM-1 and LFA-1 in educated NK cells.

Enqvist M, Ask EH, Forslund E, Carlsten M, Abrahamsen G, Béziat V, Andersson S, Schaffer M, Spurkland A, Bryceson Y, Önfelt B, Malmberg KJ.

J Immunol. 2015 May 1;194(9):4518-27. doi: 10.4049/jimmunol.1401972. Epub 2015 Mar 30.

15.

Distinct Migration and Contact Dynamics of Resting and IL-2-Activated Human Natural Killer Cells.

Olofsson PE, Forslund E, Vanherberghen B, Chechet K, Mickelin O, Ahlin AR, Everhorn T, Onfelt B.

Front Immunol. 2014 Mar 7;5:80. doi: 10.3389/fimmu.2014.00080. eCollection 2014. Erratum in: Front Immunol. 2014;5:451.

16.

Natural killer cell inhibitory receptor expression in humans and mice: a closer look.

Sternberg-Simon M, Brodin P, Pickman Y, Onfelt B, Kärre K, Malmberg KJ, Höglund P, Mehr R.

Front Immunol. 2013 Mar 26;4:65. doi: 10.3389/fimmu.2013.00065. eCollection 2013.

17.

Consequences of membrane topography.

Parmryd I, Onfelt B.

FEBS J. 2013 Jun;280(12):2775-84. doi: 10.1111/febs.12209. Epub 2013 Mar 21. Review.

18.

Live cell imaging in a micro-array of acoustic traps facilitates quantification of natural killer cell heterogeneity.

Christakou AE, Ohlin M, Vanherberghen B, Khorshidi MA, Kadri N, Frisk T, Wiklund M, Önfelt B.

Integr Biol (Camb). 2013 Apr;5(4):712-9. doi: 10.1039/c3ib20253d.

PMID:
23435966
19.

Classification of human natural killer cells based on migration behavior and cytotoxic response.

Vanherberghen B, Olofsson PE, Forslund E, Sternberg-Simon M, Khorshidi MA, Pacouret S, Guldevall K, Enqvist M, Malmberg KJ, Mehr R, Önfelt B.

Blood. 2013 Feb 21;121(8):1326-34. doi: 10.1182/blood-2012-06-439851. Epub 2013 Jan 3.

20.

Visualization of custom-tailored iron oxide nanoparticles chemistry, uptake, and toxicity.

Wilkinson K, Ekstrand-Hammarström B, Ahlinder L, Guldevall K, Pazik R, Kępiński L, Kvashnina KO, Butorin SM, Brismar H, Önfelt B, Österlund L, Seisenbaeva GA, Kessler VG.

Nanoscale. 2012 Dec 7;4(23):7383-93. doi: 10.1039/c2nr32572a.

PMID:
23070150
21.

Novel Microchip-Based Tools Facilitating Live Cell Imaging and Assessment of Functional Heterogeneity within NK Cell Populations.

Forslund E, Guldevall K, Olofsson PE, Frisk T, Christakou AE, Wiklund M, Onfelt B.

Front Immunol. 2012 Oct 5;3:300. doi: 10.3389/fimmu.2012.00300. eCollection 2012.

22.

Acoustofluidics 18: Microscopy for acoustofluidic micro-devices.

Wiklund M, Brismar H, Onfelt B.

Lab Chip. 2012 Sep 21;12(18):3221-34. doi: 10.1039/c2lc40757d. Epub 2012 Aug 8.

PMID:
22871973
23.

Plekhh2, a novel podocyte protein downregulated in human focal segmental glomerulosclerosis, is involved in matrix adhesion and actin dynamics.

Perisic L, Lal M, Hulkko J, Hultenby K, Önfelt B, Sun Y, Dunér F, Patrakka J, Betsholtz C, Uhlen M, Brismar H, Tryggvason K, Wernerson A, Pikkarainen T.

Kidney Int. 2012 Nov;82(10):1071-83. doi: 10.1038/ki.2012.252. Epub 2012 Jul 25.

24.

Ultrasonic manipulation of single cells.

Wiklund M, Onfelt B.

Methods Mol Biol. 2012;853:177-96. doi: 10.1007/978-1-61779-567-1_14.

PMID:
22323148
25.

Light-induced cytotoxicity of a photochromic spiropyran.

Nilsson JR, Li S, Önfelt B, Andréasson J.

Chem Commun (Camb). 2011 Oct 21;47(39):11020-2. doi: 10.1039/c1cc13561a. Epub 2011 Sep 12.

PMID:
21909522
26.

Analysis of transient migration behavior of natural killer cells imaged in situ and in vitro.

Khorshidi MA, Vanherberghen B, Kowalewski JM, Garrod KR, Lindström S, Andersson-Svahn H, Brismar H, Cahalan MD, Önfelt B.

Integr Biol (Camb). 2011 Jul;3(7):770-8. doi: 10.1039/c1ib00007a. Epub 2011 Jun 20.

PMID:
21687858
27.

A silicon-glass microwell platform for high-resolution imaging and high-content screening with single cell resolution.

Frisk TW, Khorshidi MA, Guldevall K, Vanherberghen B, Önfelt B.

Biomed Microdevices. 2011 Aug;13(4):683-93. doi: 10.1007/s10544-011-9538-2.

PMID:
21465090
28.

Imaging immune surveillance of individual natural killer cells confined in microwell arrays.

Guldevall K, Vanherberghen B, Frisk T, Hurtig J, Christakou AE, Manneberg O, Lindström S, Andersson-Svahn H, Wiklund M, Önfelt B.

PLoS One. 2010 Nov 12;5(11):e15453. doi: 10.1371/journal.pone.0015453.

29.

Ultrasound-controlled cell aggregation in a multi-well chip.

Vanherberghen B, Manneberg O, Christakou A, Frisk T, Ohlin M, Hertz HM, Önfelt B, Wiklund M.

Lab Chip. 2010 Oct 21;10(20):2727-32. doi: 10.1039/c004707d. Epub 2010 Aug 31.

PMID:
20820481
30.

Intercellular nanotubes: insights from imaging studies and beyond.

Hurtig J, Chiu DT, Onfelt B.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010 May-Jun;2(3):260-76. doi: 10.1002/wnan.80. Review.

31.

Flow-free transport of cells in microchannels by frequency-modulated ultrasound.

Manneberg O, Vanherberghen B, Onfelt B, Wiklund M.

Lab Chip. 2009 Mar 21;9(6):833-7. doi: 10.1039/b816675g. Epub 2009 Feb 2.

PMID:
19255666
32.

Live cell linear dichroism imaging reveals extensive membrane ruffling within the docking structure of natural killer cell immune synapses.

Benninger RK, Vanherberghen B, Young S, Taner SB, Culley FJ, Schnyder T, Neil MA, Wüstner D, French PM, Davis DM, Onfelt B.

Biophys J. 2009 Jan;96(2):L13-5. doi: 10.1016/j.bpj.2008.10.005.

33.

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission.

Sowinski S, Jolly C, Berninghausen O, Purbhoo MA, Chauveau A, Köhler K, Oddos S, Eissmann P, Brodsky FM, Hopkins C, Onfelt B, Sattentau Q, Davis DM.

Nat Cell Biol. 2008 Feb;10(2):211-9. doi: 10.1038/ncb1682. Epub 2008 Jan 13.

PMID:
18193035
34.

Fluorescence-lifetime imaging of DNA-dye interactions within continuous-flow microfluidic systems.

Benninger RK, Hofmann O, Onfelt B, Munro I, Dunsby C, Davis DM, Neil MA, French PM, de Mello AJ.

Angew Chem Int Ed Engl. 2007;46(13):2228-31. No abstract available.

PMID:
17436333
35.
36.

Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria.

Onfelt B, Nedvetzki S, Benninger RK, Purbhoo MA, Sowinski S, Hume AN, Seabra MC, Neil MA, French PM, Davis DM.

J Immunol. 2006 Dec 15;177(12):8476-83.

37.

Long-distance calls between cells connected by tunneling nanotubules.

Onfelt B, Purbhoo MA, Nedvetzki S, Sowinski S, Davis DM.

Sci STKE. 2005 Dec 6;2005(313):pe55. Review.

PMID:
16333019
38.

Fluorescence imaging of two-photon linear dichroism: cholesterol depletion disrupts molecular orientation in cell membranes.

Benninger RK, Onfelt B, Neil MA, Davis DM, French PM.

Biophys J. 2005 Jan;88(1):609-22. Epub 2004 Nov 1.

39.

Can membrane nanotubes facilitate communication between immune cells?

Onfelt B, Davis DM.

Biochem Soc Trans. 2004 Nov;32(Pt 5):676-8.

PMID:
15493985
40.

Control of immune responses by trafficking cell surface proteins, vesicles and lipid rafts to and from the immunological synapse.

Taner SB, Onfelt B, Pirinen NJ, McCann FE, Magee AI, Davis DM.

Traffic. 2004 Sep;5(9):651-61. Review.

41.

Cutting edge: Membrane nanotubes connect immune cells.

Onfelt B, Nedvetzki S, Yanagi K, Davis DM.

J Immunol. 2004 Aug 1;173(3):1511-3.

42.

Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D.

Eleme K, Taner SB, Onfelt B, Collinson LM, McCann FE, Chalupny NJ, Cosman D, Hopkins C, Magee AI, Davis DM.

J Exp Med. 2004 Apr 5;199(7):1005-10. Epub 2004 Mar 29.

43.

Picosecond Kerr-gated time-resolved resonance Raman spectroscopy of the [Ru(phen)(2)dppz](2+) interaction with DNA.

Olofsson J, Onfelt B, Lincoln P, Nordén B, Matousek P, Parker AW, Tuite E.

J Inorg Biochem. 2002 Jul 25;91(1):286-97.

PMID:
12121787
45.

Enantioselective DNA threading dynamics by phenazine-linked.

Onfelt B, Lincoln P, Nordén B.

J Am Chem Soc. 2001 Apr 25;123(16):3630-7.

PMID:
11457094
46.

Femtosecond linear dichroism of DNA-intercalating chromophores: solvation and charge separation dynamics of [Ru(phen)2dppz]2+ systems.

Onfelt B, Lincoln P, Nordén B, Baskin JS, Zewail AH.

Proc Natl Acad Sci U S A. 2000 May 23;97(11):5708-13.

47.

Probing DNA conductivity with photoinduced electron transfer and scanning tunneling microscopy.

Tuite E, Lincoln P, Olofsson J, Becker HC, Onfelt B, Erts D, Nordén B.

J Biomol Struct Dyn. 2000;17 Suppl 1:277-83.

PMID:
22607435

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