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Items: 41

1.

The human long non-coding RNA gene RMRP has pleiotropic effects and regulates cell-cycle progression at G2.

Vakkilainen S, Skoog T, Einarsdottir E, Middleton A, Pekkinen M, Öhman T, Katayama S, Krjutškov K, Kovanen PE, Varjosalo M, Lindqvist A, Kere J, Mäkitie O.

Sci Rep. 2019 Sep 24;9(1):13758. doi: 10.1038/s41598-019-50334-6.

2.

A β2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation.

Guenther C, Faisal I, Uotila LM, Asens ML, Harjunpää H, Savinko T, Öhman T, Yao S, Moser M, Morris SW, Tojkander S, Fagerholm SC.

Front Immunol. 2019 May 28;10:1138. doi: 10.3389/fimmu.2019.01138. eCollection 2019.

3.

FGFR4 phosphorylates MST1 to confer breast cancer cells resistance to MST1/2-dependent apoptosis.

Turunen SP, von Nandelstadh P, Öhman T, Gucciardo E, Seashore-Ludlow B, Martins B, Rantanen V, Li H, Höpfner K, Östling P, Varjosalo M, Lehti K.

Cell Death Differ. 2019 Mar 22. doi: 10.1038/s41418-019-0321-x. [Epub ahead of print]

PMID:
30903103
4.

Talin-mediated force transmission and talin rod domain unfolding independently regulate adhesion signaling.

Rahikainen R, Öhman T, Turkki P, Varjosalo M, Hytönen VP.

J Cell Sci. 2019 Apr 3;132(7). pii: jcs226514. doi: 10.1242/jcs.226514.

5.

Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion.

Brix DM, Tvingsholm SA, Hansen MB, Clemmensen KB, Ohman T, Siino V, Lambrughi M, Hansen K, Puustinen P, Gromova I, James P, Papaleo E, Varjosalo M, Moreira J, Jäättelä M, Kallunki T.

Oncogene. 2019 Apr;38(17):3170-3184. doi: 10.1038/s41388-018-0653-x. Epub 2019 Jan 8.

6.

Differences in the dietary requirement for vitamin D among Caucasian and East African women at Northern latitude.

Cashman KD, Ritz C, Adebayo FA, Dowling KG, Itkonen ST, Öhman T, Skaffari E, Saarnio EM, Kiely M, Lamberg-Allardt C.

Eur J Nutr. 2019 Sep;58(6):2281-2291. doi: 10.1007/s00394-018-1775-1. Epub 2018 Jul 18.

PMID:
30022296
7.

Systems pathology analysis identifies neurodegenerative nature of age-related vitreoretinal interface diseases.

Öhman T, Tamene F, Göös H, Loukovaara S, Varjosalo M.

Aging Cell. 2018 Oct;17(5):e12809. doi: 10.1111/acel.12809. Epub 2018 Jul 2.

8.

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.

Liu X, Salokas K, Tamene F, Jiu Y, Weldatsadik RG, Öhman T, Varjosalo M.

Nat Commun. 2018 Mar 22;9(1):1188. doi: 10.1038/s41467-018-03523-2.

9.

Vitamin D intake, serum 25-hydroxyvitamin D status and response to moderate vitamin D3 supplementation: a randomised controlled trial in East African and Finnish women.

Adebayo FA, Itkonen ST, Öhman T, Skaffari E, Saarnio EM, Erkkola M, Cashman KD, Lamberg-Allardt C.

Br J Nutr. 2018 Feb;119(4):431-441. doi: 10.1017/S000711451700397X.

PMID:
29498350
10.

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins.

Bulanova D, Ianevski A, Bugai A, Akimov Y, Kuivanen S, Paavilainen H, Kakkola L, Nandania J, Turunen L, Ohman T, Ala-Hongisto H, Pesonen HM, Kuisma MS, Honkimaa A, Walton EL, Oksenych V, Lorey MB, Guschin D, Shim J, Kim J, Than TT, Chang SY, Hukkanen V, Kulesskiy E, Marjomaki VS, Julkunen I, Nyman TA, Matikainen S, Saarela JS, Sane F, Hober D, Gabriel G, De Brabander JK, Martikainen M, Windisch MP, Min JY, Bruzzone R, Aittokallio T, Vähä-Koskela M, Vapalahti O, Pulk A, Velagapudi V, Kainov DE.

Viruses. 2017 Sep 25;9(10). pii: E271. doi: 10.3390/v9100271.

11.

Performance of a capnodynamic method estimating effective pulmonary blood flow during transient and sustained hypercapnia.

Sigmundsson TS, Öhman T, Hallbäck M, Redondo E, Sipmann FS, Wallin M, Oldner A, Hällsjö Sander C, Björne H.

J Clin Monit Comput. 2018 Apr;32(2):311-319. doi: 10.1007/s10877-017-0021-3. Epub 2017 May 11.

12.

Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes.

Anastasina M, Le May N, Bugai A, Fu Y, Söderholm S, Gaelings L, Ohman T, Tynell J, Kyttänen S, Barboric M, Nyman TA, Matikainen S, Julkunen I, Butcher SJ, Egly JM, Kainov DE.

Biochim Biophys Acta. 2016 Nov;1859(11):1440-1448. doi: 10.1016/j.bbagrm.2016.09.005. Epub 2016 Sep 21.

PMID:
27664935
13.

Phosphoproteomics to Characterize Host Response During Influenza A Virus Infection of Human Macrophages.

Söderholm S, Kainov DE, Öhman T, Denisova OV, Schepens B, Kulesskiy E, Imanishi SY, Corthals G, Hintsanen P, Aittokallio T, Saelens X, Matikainen S, Nyman TA.

Mol Cell Proteomics. 2016 Oct;15(10):3203-3219. Epub 2016 Aug 2.

15.

Activating stimuli induce platelet microRNA modulation and proteome reorganisation.

Cimmino G, Tarallo R, Nassa G, De Filippo MR, Giurato G, Ravo M, Rizzo F, Conte S, Pellegrino G, Cirillo P, Calabro P, Öhman T, Nyman TA, Weisz A, Golino P.

Thromb Haemost. 2015 Jul;114(1):96-108. doi: 10.1160/TH14-09-0726. Epub 2015 Apr 23.

PMID:
25903651
16.

Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.

Jokinen R, Lahtinen T, Marttinen P, Myöhänen M, Ruotsalainen P, Yeung N, Shvetsova A, Kastaniotis AJ, Hiltunen JK, Öhman T, Nyman TA, Weiler H, Battersby BJ.

Genetics. 2015 May;200(1):221-35. doi: 10.1534/genetics.115.175596. Epub 2015 Mar 25.

17.

Phosphoproteome characterization reveals that Sendai virus infection activates mTOR signaling in human epithelial cells.

Öhman T, Söderholm S, Paidikondala M, Lietzén N, Matikainen S, Nyman TA.

Proteomics. 2015 Jun;15(12):2087-97. doi: 10.1002/pmic.201400586. Epub 2015 Apr 27.

PMID:
25764225
18.

Uncovering surface-exposed antigens of Lactobacillus rhamnosus by cell shaving proteomics and two-dimensional immunoblotting.

Espino E, Koskenniemi K, Mato-Rodriguez L, Nyman TA, Reunanen J, Koponen J, Öhman T, Siljamäki P, Alatossava T, Varmanen P, Savijoki K.

J Proteome Res. 2015 Feb 6;14(2):1010-24. doi: 10.1021/pr501041a. Epub 2014 Dec 22.

PMID:
25531588
19.

Statistical detection of quantitative protein biomarkers provides insights into signaling networks deregulated in acute myeloid leukemia.

Elo LL, Karjalainen R, Ohman T, Hintsanen P, Nyman TA, Heckman CA, Aittokallio T.

Proteomics. 2014 Nov;14(21-22):2443-53. doi: 10.1002/pmic.201300460. Epub 2014 Oct 15.

PMID:
25211154
20.

Isolation and characterization of platelet-derived extracellular vesicles.

Aatonen MT, Ohman T, Nyman TA, Laitinen S, Grönholm M, Siljander PR.

J Extracell Vesicles. 2014 Aug 6;3. doi: 10.3402/jev.v3.24692. eCollection 2014.

21.

PhosFox: a bioinformatics tool for peptide-level processing of LC-MS/MS-based phosphoproteomic data.

Söderholm S, Hintsanen P, Öhman T, Aittokallio T, Nyman TA.

Proteome Sci. 2014 Jun 26;12:36. doi: 10.1186/1477-5956-12-36. eCollection 2014.

22.

Phosphoproteomics combined with quantitative 14-3-3-affinity capture identifies SIRT1 and RAI as novel regulators of cytosolic double-stranded RNA recognition pathway.

Öhman T, Söderholm S, Hintsanen P, Välimäki E, Lietzén N, MacKintosh C, Aittokallio T, Matikainen S, Nyman TA.

Mol Cell Proteomics. 2014 Oct;13(10):2604-17. doi: 10.1074/mcp.M114.038968. Epub 2014 Jul 5.

23.

Reference interval determination for anabasine: a biomarker of active tobacco use.

Suh-Lailam BB, Haglock-Adler CJ, Carlisle HJ, Ohman T, McMillin GA.

J Anal Toxicol. 2014 Sep;38(7):416-20. doi: 10.1093/jat/bku059. Epub 2014 Jun 17.

PMID:
24939383
24.

Dectin-1 pathway activates robust autophagy-dependent unconventional protein secretion in human macrophages.

Öhman T, Teirilä L, Lahesmaa-Korpinen AM, Cypryk W, Veckman V, Saijo S, Wolff H, Hautaniemi S, Nyman TA, Matikainen S.

J Immunol. 2014 Jun 15;192(12):5952-62. doi: 10.4049/jimmunol.1303213. Epub 2014 May 7.

25.

Quantitative proteomics of extracellular vesicles released from human monocyte-derived macrophages upon β-glucan stimulation.

Cypryk W, Ohman T, Eskelinen EL, Matikainen S, Nyman TA.

J Proteome Res. 2014 May 2;13(5):2468-77. doi: 10.1021/pr4012552. Epub 2014 Apr 16.

PMID:
24670152
26.

Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice.

Kakkola L, Denisova OV, Tynell J, Viiliäinen J, Ysenbaert T, Matos RC, Nagaraj A, Ohman T, Kuivanen S, Paavilainen H, Feng L, Yadav B, Julkunen I, Vapalahti O, Hukkanen V, Stenman J, Aittokallio T, Verschuren EW, Ojala PM, Nyman T, Saelens X, Dzeyk K, Kainov DE.

Cell Death Dis. 2013 Jul 25;4:e742. doi: 10.1038/cddis.2013.267.

27.

Molecular networks of DYX1C1 gene show connection to neuronal migration genes and cytoskeletal proteins.

Tammimies K, Vitezic M, Matsson H, Le Guyader S, Bürglin TR, Ohman T, Strömblad S, Daub CO, Nyman TA, Kere J, Tapia-Páez I.

Biol Psychiatry. 2013 Mar 15;73(6):583-90. doi: 10.1016/j.biopsych.2012.08.012. Epub 2012 Oct 1.

PMID:
23036959
28.

Quantitative subcellular proteome and secretome profiling of influenza A virus-infected human primary macrophages.

Lietzén N, Ohman T, Rintahaka J, Julkunen I, Aittokallio T, Matikainen S, Nyman TA.

PLoS Pathog. 2011 May;7(5):e1001340. doi: 10.1371/journal.ppat.1001340. Epub 2011 May 12.

29.

Recognition of cytoplasmic RNA results in cathepsin-dependent inflammasome activation and apoptosis in human macrophages.

Rintahaka J, Lietzén N, Öhman T, Nyman TA, Matikainen S.

J Immunol. 2011 Mar 1;186(5):3085-92. doi: 10.4049/jimmunol.1002051. Epub 2011 Jan 21.

30.

Cytosolic RNA recognition pathway activates 14-3-3 protein mediated signaling and caspase-dependent disruption of cytokeratin network in human keratinocytes.

Ohman T, Lietzén N, Välimäki E, Melchjorsen J, Matikainen S, Nyman TA.

J Proteome Res. 2010 Mar 5;9(3):1549-64. doi: 10.1021/pr901040u.

PMID:
20070120
31.

PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells.

Tuomi S, Mai A, Nevo J, Laine JO, Vilkki V, Ohman TJ, Gahmberg CG, Parker PJ, Ivaska J.

Sci Signal. 2009 Jun 30;2(77):ra32. doi: 10.1126/scisignal.2000135.

32.

Actin and RIG-I/MAVS signaling components translocate to mitochondria upon influenza A virus infection of human primary macrophages.

Ohman T, Rintahaka J, Kalkkinen N, Matikainen S, Nyman TA.

J Immunol. 2009 May 1;182(9):5682-92. doi: 10.4049/jimmunol.0803093.

33.

Echoviruses 1 and 8 are closely related genetically, and bind to similar determinants within the VLA-2 I domain.

Ohman T, King SL, Krithivas A, Cunningham J, Dickeson SK, Santoro SA, Bergelson JM.

Virus Res. 2001 Jul;76(1):1-8.

PMID:
11376841
34.

Multiple regions within the coxsackievirus and adenovirus receptor cytoplasmic domain are required for basolateral sorting.

Cohen CJ, Gaetz J, Ohman T, Bergelson JM.

J Biol Chem. 2001 Jul 6;276(27):25392-8. Epub 2001 Apr 20.

35.

Analysis of mouse intron 7 DNA sequence of the APP gene: comparison with the human homologue.

Li L, Ohman T, Deeb SS, Fukuchi KI.

DNA Seq. 1999;10(4-5):219-28.

PMID:
10727079
36.

Survival, lung injury, and lung protein nitration in heterozygous MnSOD knockout mice in hyperoxia.

Jackson RM, Helton ES, Viera L, Ohman T.

Exp Lung Res. 1999 Oct-Nov;25(7):631-46.

PMID:
10598322
37.

Hypoxic modulation of manganese superoxide dismutase promoter activity and gene expression in lung epithelial cells.

Ohman T, Parish G, Jackson RM.

Am J Respir Cell Mol Biol. 1999 Jul;21(1):119-27.

PMID:
10385600
38.

Polymorphic tetranucleotide repeat site within intron 7 of the beta-amyloid precursor protein gene and its lack of association with Alzheimer's disease.

Li L, Perry R, Wu J, Pham D, Ohman T, Harrell LE, Go RC, Fukuchi K.

Hum Genet. 1998 Jul;103(1):86-9.

PMID:
9737782
39.

Expression of apolipoprotein E inhibits aggregation of the C-terminal fragments of beta-amyloid precursor protein.

Ohman T, Dang N, LeBoeuf RC, Furlong CE, Fukuchi K.

Neurosci Lett. 1996 May 24;210(1):65-8.

PMID:
8762193
41.

[Professional organizations as an influence].

Ohman T.

Sairaanhoitaja. 1992;(8):6-9. Finnish, Swedish. No abstract available.

PMID:
1288724

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