Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 41

1.

Targeted delivery of antisense oligonucleotides to pancreatic β-cells.

Ämmälä C, Drury WJ 3rd, Knerr L, Ahlstedt I, Stillemark-Billton P, Wennberg-Huldt C, Andersson EM, Valeur E, Jansson-Löfmark R, Janzén D, Sundström L, Meuller J, Claesson J, Andersson P, Johansson C, Lee RG, Prakash TP, Seth PP, Monia BP, Andersson S.

Sci Adv. 2018 Oct 17;4(10):eaat3386. doi: 10.1126/sciadv.aat3386. eCollection 2018 Oct.

2.

Publisher Correction: Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model.

Bauer S, Wennberg Huldt C, Kanebratt KP, Durieux I, Gunne D, Andersson S, Ewart L, Haynes WG, Maschmeyer I, Winter A, Ämmälä C, Marx U, Andersson TB.

Sci Rep. 2018 Jan 23;8(1):1672. doi: 10.1038/s41598-018-20340-1.

3.

Functional coupling of human pancreatic islets and liver spheroids on-a-chip: Towards a novel human ex vivo type 2 diabetes model.

Bauer S, Wennberg Huldt C, Kanebratt KP, Durieux I, Gunne D, Andersson S, Ewart L, Haynes WG, Maschmeyer I, Winter A, Ämmälä C, Marx U, Andersson TB.

Sci Rep. 2017 Nov 6;7(1):14620. doi: 10.1038/s41598-017-14815-w. Erratum in: Sci Rep. 2018 Jan 23;8(1):1672.

4.

Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.

Segerstolpe Å, Palasantza A, Eliasson P, Andersson EM, Andréasson AC, Sun X, Picelli S, Sabirsh A, Clausen M, Bjursell MK, Smith DM, Kasper M, Ämmälä C, Sandberg R.

Cell Metab. 2016 Oct 11;24(4):593-607. doi: 10.1016/j.cmet.2016.08.020. Epub 2016 Sep 22.

5.

Discovery of 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines as orally available G protein-coupled receptor 119 agonists.

Katamreddy SR, Carpenter AJ, Ammala CE, Boros EE, Brashear RL, Briscoe CP, Bullard SR, Caldwell RD, Conlee CR, Croom DK, Hart SM, Heyer DO, Johnson PR, Kashatus JA, Minick DJ, Peckham GE, Ross SA, Roller SG, Samano VA, Sauls HR, Tadepalli SM, Thompson JB, Xu Y, Way JM.

J Med Chem. 2012 Dec 27;55(24):10972-94. doi: 10.1021/jm301404a. Epub 2012 Dec 12.

PMID:
23214471
6.

2,5-Disubstituted pyridines as potent GPR119 agonists.

Wu Y, Kuntz JD, Carpenter AJ, Fang J, Sauls HR, Gomez DJ, Ammala C, Xu Y, Hart S, Tadepalli S.

Bioorg Med Chem Lett. 2010 Apr 15;20(8):2577-81. doi: 10.1016/j.bmcl.2010.02.083. Epub 2010 Feb 25.

PMID:
20227877
7.

Positional cloning of "Lisch-Like", a candidate modifier of susceptibility to type 2 diabetes in mice.

Dokmanovic-Chouinard M, Chung WK, Chevre JC, Watson E, Yonan J, Wiegand B, Bromberg Y, Wakae N, Wright CV, Overton J, Ghosh S, Sathe GM, Ammala CE, Brown KK, Ito R, LeDuc C, Solomon K, Fischer SG, Leibel RL.

PLoS Genet. 2008 Jul 25;4(7):e1000137. doi: 10.1371/journal.pgen.1000137.

8.

Kv2.1 ablation alters glucose-induced islet electrical activity, enhancing insulin secretion.

Jacobson DA, Kuznetsov A, Lopez JP, Kash S, Ammälä CE, Philipson LH.

Cell Metab. 2007 Sep;6(3):229-35.

9.

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.

Briscoe CP, Peat AJ, McKeown SC, Corbett DF, Goetz AS, Littleton TR, McCoy DC, Kenakin TP, Andrews JL, Ammala C, Fornwald JA, Ignar DM, Jenkinson S.

Br J Pharmacol. 2006 Jul;148(5):619-28. Epub 2006 May 15.

10.

Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier.

Hildyard JC, Ammälä C, Dukes ID, Thomson SA, Halestrap AP.

Biochim Biophys Acta. 2005 Apr-May;1707(2-3):221-30. Epub 2004 Dec 30.

11.

Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.

Straub SG, Cosgrove KE, Ammälä C, Shepherd RM, O'Brien RE, Barnes PD, Kuchinski N, Chapman JC, Schaeppi M, Glaser B, Lindley KJ, Sharp GW, Aynsley-Green A, Dunne MJ.

Diabetes. 2001 Feb;50(2):329-39.

12.

Hyperinsulinism of infancy: towards an understanding of unregulated insulin release. European Network for Research into Hyperinsulinism in Infancy.

Shepherd RM, Cosgrove KE, O'Brien RE, Barnes PD, Ammälä C, Dunne MJ.

Arch Dis Child Fetal Neonatal Ed. 2000 Mar;82(2):F87-97. Review.

13.

ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.

Chapman JC, McClenaghan NH, Cosgrove KE, Hashmi MN, Shepherd RM, Giesberts AN, White SJ, Ammälä C, Flatt PR, Dunne MJ.

Diabetes. 1999 Dec;48(12):2349-57.

PMID:
10580423
14.

A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland.

Otonkoski T, Ammälä C, Huopio H, Cote GJ, Chapman J, Cosgrove K, Ashfield R, Huang E, Komulainen J, Ashcroft FM, Dunne MJ, Kere J, Thomas PM.

Diabetes. 1999 Feb;48(2):408-15.

PMID:
10334322
15.

Potassium Channels, Sulphonylurea Receptors and Control of Insulin Release.

Dunne MJ, Cosgrove KE, Shepherd RM, Ämmälä C.

Trends Endocrinol Metab. 1999 May;10(4):146-152.

PMID:
10322409
16.

Characterization of ion channels in stimulus-secretion coupling in pancreatic islets.

Ammälä C, Kane C, Cosgrove KE, Chapman JC, Aynsley-Green A, Lindley KJ, Dunne JM.

Digestion. 1997;58 Suppl 2:81-5. Review.

PMID:
9302496
17.

Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes.

Gribble FM, Ashfield R, Ammälä C, Ashcroft FM.

J Physiol. 1997 Jan 1;498 ( Pt 1):87-98.

18.

Ca(2+)- and GTP-dependent exocytosis in mouse pancreatic beta-cells involves both common and distinct steps.

Proks P, Eliasson L, Ammälä C, Rorsman P, Ashcroft FM.

J Physiol. 1996 Oct 1;496 ( Pt 1):255-64.

20.

Endocytosis of secretory granules in mouse pancreatic beta-cells evoked by transient elevation of cytosolic calcium.

Eliasson L, Proks P, Ammälä C, Ashcroft FM, Bokvist K, Renström E, Rorsman P, Smith PA.

J Physiol. 1996 Jun 15;493 ( Pt 3):755-67.

21.

PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells.

Eliasson L, Renström E, Ammälä C, Berggren PO, Bertorello AM, Bokvist K, Chibalin A, Deeney JT, Flatt PR, Gäbel J, Gromada J, Larsson O, Lindström P, Rhodes CJ, Rorsman P.

Science. 1996 Feb 9;271(5250):813-5.

PMID:
8628999
22.

Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels.

Ammälä C, Moorhouse A, Gribble F, Ashfield R, Proks P, Smith PA, Sakura H, Coles B, Ashcroft SJ, Ashcroft FM.

Nature. 1996 Feb 8;379(6565):545-8.

PMID:
8596634
24.

Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain.

Bond CT, Ammälä C, Ashfield R, Blair TA, Gribble F, Khan RN, Lee K, Proks P, Rowe IC, Sakura H, et al.

FEBS Lett. 1995 Jun 19;367(1):61-6.

26.

Intracellular pH, cytosolic calcium concentration and electrical activity in RINm5F insulinoma cells.

Best L, Ammala C, Rorsman P, Tomlinson S.

Biochim Biophys Acta. 1994 Jun 1;1192(1):107-11.

PMID:
8204639
27.

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

Ammälä C, Eliasson L, Bokvist K, Berggren PO, Honkanen RE, Sjöholm A, Rorsman P.

Proc Natl Acad Sci U S A. 1994 May 10;91(10):4343-7.

28.

Ion channels, electrical activity and insulin secretion.

Rorsman P, Bokvist K, Ammälä C, Eliasson L, Renström E, Gäbel J.

Diabete Metab. 1994 Mar-Apr;20(2):138-45. Review.

PMID:
7528694
29.

Stimulus-secretion coupling in pancreatic beta cells.

Ashcroft FM, Proks P, Smith PA, Ammälä C, Bokvist K, Rorsman P.

J Cell Biochem. 1994;55 Suppl:54-65. Review.

PMID:
7929618
30.

Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells.

Ammälä C, Eliasson L, Bokvist K, Larsson O, Ashcroft FM, Rorsman P.

J Physiol. 1993 Dec;472:665-88.

31.

Increased activity of L-type Ca2+ channels exposed to serum from patients with type I diabetes.

Juntti-Berggren L, Larsson O, Rorsman P, Ammälä C, Bokvist K, Wåhlander K, Nicotera P, Dypbukt J, Orrenius S, Hallberg A, et al.

Science. 1993 Jul 2;261(5117):86-90.

PMID:
7686306
32.

Calcium-independent potentiation of insulin release by cyclic AMP in single beta-cells.

Ammälä C, Ashcroft FM, Rorsman P.

Nature. 1993 May 27;363(6427):356-8.

PMID:
7684514
33.

Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells.

Larsson O, Ammälä C, Bokvist K, Fredholm B, Rorsman P.

J Physiol. 1993 Apr;463:349-65.

34.

Demonstration of a novel apamin-insensitive calcium-activated K+ channel in mouse pancreatic B cells.

Ammälä C, Bokvist K, Larsson O, Berggren PO, Rorsman P.

Pflugers Arch. 1993 Feb;422(5):443-8.

PMID:
8474849
35.
36.

Inhibition of L-type calcium channels by internal GTP [gamma S] in mouse pancreatic beta cells.

Ammälä C, Berggren PO, Bokvist K, Rorsman P.

Pflugers Arch. 1992 Jan;420(1):72-7.

PMID:
1313169
37.

Inositol trisphosphate-dependent periodic activation of a Ca(2+)-activated K+ conductance in glucose-stimulated pancreatic beta-cells.

Ammälä C, Larsson O, Berggren PO, Bokvist K, Juntti-Berggren L, Kindmark H, Rorsman P.

Nature. 1991 Oct 31;353(6347):849-52.

PMID:
1719424
38.

Alpha 2-adrenoreceptor stimulation does not inhibit L-type calcium channels in mouse pancreatic beta-cells.

Bokvist K, Ammälä C, Berggren PO, Rorsman P, Wåhlander K.

Biosci Rep. 1991 Jun;11(3):147-57.

PMID:
1659917
39.

Inhibition of ATP-regulated K(+)-channels by a photoactivatable ATP-analogue in mouse pancreatic beta-cells.

Ammälä C, Bokvist K, Galt S, Rorsman P.

Biochim Biophys Acta. 1991 May 17;1092(3):347-9.

PMID:
2049403
40.

Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K(+)-channels in mouse pancreatic beta-cells.

Bokvist K, Ammälä C, Ashcroft FM, Berggren PO, Larsson O, Rorsman P.

Proc Biol Sci. 1991 Feb 22;243(1307):139-44.

PMID:
1676517
41.

Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells.

Rorsman P, Bokvist K, Ammälä C, Arkhammar P, Berggren PO, Larsson O, Wåhlander K.

Nature. 1991 Jan 3;349(6304):77-9.

PMID:
1898674

Supplemental Content

Loading ...
Support Center