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Items: 1 to 50 of 82

1.

De Novo Emergence of Peptides That Confer Antibiotic Resistance.

Knopp M, Gudmundsdottir JS, Nilsson T, König F, Warsi O, Rajer F, Ädelroth P, Andersson DI.

MBio. 2019 Jun 4;10(3). pii: e00837-19. doi: 10.1128/mBio.00837-19.

2.

Insights into the mechanism of nitric oxide reductase from a FeB -depleted variant.

Kahle M, Blomberg MRA, Jareck S, Ädelroth P.

FEBS Lett. 2019 Jun;593(12):1351-1359. doi: 10.1002/1873-3468.13436. Epub 2019 May 29.

PMID:
31077353
3.

Structure of a functional obligate complex III2IV2 respiratory supercomplex from Mycobacterium smegmatis.

Wiseman B, Nitharwal RG, Fedotovskaya O, Schäfer J, Guo H, Kuang Q, Benlekbir S, Sjöstrand D, Ädelroth P, Rubinstein JL, Brzezinski P, Högbom M.

Nat Struct Mol Biol. 2018 Dec;25(12):1128-1136. doi: 10.1038/s41594-018-0160-3. Epub 2018 Dec 5.

PMID:
30518849
4.

Extraction and liposome reconstitution of membrane proteins with their native lipids without the use of detergents.

Smirnova IA, Ädelroth P, Brzezinski P.

Sci Rep. 2018 Oct 8;8(1):14950. doi: 10.1038/s41598-018-33208-1.

5.

Mechanism of proton transfer through the KC proton pathway in the Vibrio cholerae cbb3 terminal oxidase.

Ahn YO, Albertsson I, Gennis RB, Ädelroth P.

Biochim Biophys Acta Bioenerg. 2018 Nov;1859(11):1191-1198. doi: 10.1016/j.bbabio.2018.08.002. Epub 2018 Aug 22.

PMID:
30251700
6.

Mechanisms for enzymatic reduction of nitric oxide to nitrous oxide - A comparison between nitric oxide reductase and cytochrome c oxidase.

Blomberg MRA, Ädelroth P.

Biochim Biophys Acta Bioenerg. 2018 Nov;1859(11):1223-1234. doi: 10.1016/j.bbabio.2018.09.368. Epub 2018 Sep 21.

PMID:
30248312
7.

Regulation of cytochrome c oxidase activity by modulation of the catalytic site.

Schäfer J, Dawitz H, Ott M, Ädelroth P, Brzezinski P.

Sci Rep. 2018 Jul 30;8(1):11397. doi: 10.1038/s41598-018-29567-4.

8.

The insertion of the non-heme FeB cofactor into nitric oxide reductase from P. denitrificans depends on NorQ and NorD accessory proteins.

Kahle M, Ter Beek J, Hosler JP, Ädelroth P.

Biochim Biophys Acta Bioenerg. 2018 Jun 3. pii: S0005-2728(18)30138-5. doi: 10.1016/j.bbabio.2018.05.020. [Epub ahead of print]

PMID:
29874552
9.

Structural and functional heterogeneity of cytochrome c oxidase in S. cerevisiae.

Schäfer J, Dawitz H, Ott M, Ädelroth P, Brzezinski P.

Biochim Biophys Acta Bioenerg. 2018 Sep;1859(9):699-704. doi: 10.1016/j.bbabio.2018.05.004. Epub 2018 May 8.

PMID:
29746825
10.

Solution NMR structure of yeast Rcf1, a protein involved in respiratory supercomplex formation.

Zhou S, Pettersson P, Huang J, Sjöholm J, Sjöstrand D, Pomès R, Högbom M, Brzezinski P, Mäler L, Ädelroth P.

Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):3048-3053. doi: 10.1073/pnas.1712061115. Epub 2018 Mar 5.

11.

Characterization of the quinol-dependent nitric oxide reductase from the pathogen Neisseria meningitidis, an electrogenic enzyme.

Gonska N, Young D, Yuki R, Okamoto T, Hisano T, Antonyuk S, Hasnain SS, Muramoto K, Shiro Y, Tosha T, Ädelroth P.

Sci Rep. 2018 Feb 26;8(1):3637. doi: 10.1038/s41598-018-21804-0.

12.

NMR Study of Rcf2 Reveals an Unusual Dimeric Topology in Detergent Micelles.

Zhou S, Pettersson P, Brzezinski P, Ädelroth P, Mäler L.

Chembiochem. 2018 Mar 2;19(5):444-447. doi: 10.1002/cbic.201700664. Epub 2018 Jan 25.

PMID:
29240987
13.

The mechanism for oxygen reduction in cytochrome c dependent nitric oxide reductase (cNOR) as obtained from a combination of theoretical and experimental results.

Blomberg MRA, Ädelroth P.

Biochim Biophys Acta Bioenerg. 2017 Nov;1858(11):884-894. doi: 10.1016/j.bbabio.2017.08.005. Epub 2017 Aug 8.

14.

Modulation of protein function in membrane mimetics: Characterization of P. denitrificans cNOR in nanodiscs or liposomes.

Ter Beek J, Kahle M, Ädelroth P.

Biochim Biophys Acta Biomembr. 2017 Oct;1859(10):1951-1961. doi: 10.1016/j.bbamem.2017.06.017. Epub 2017 Jun 28.

15.

Splitting of the O-O bond at the heme-copper catalytic site of respiratory oxidases.

Poiana F, von Ballmoos C, Gonska N, Blomberg MRA, Ädelroth P, Brzezinski P.

Sci Adv. 2017 Jun 16;3(6):e1700279. doi: 10.1126/sciadv.1700279. eCollection 2017 Jun.

16.

Insights Into How Heme Reduction Potentials Modulate Enzymatic Activities of a Myoglobin-based Functional Oxidase.

Bhagi-Damodaran A, Kahle M, Shi Y, Zhang Y, Ädelroth P, Lu Y.

Angew Chem Int Ed Engl. 2017 Jun 1;56(23):6622-6626. doi: 10.1002/anie.201701916. Epub 2017 May 4.

17.

Reaction of S. cerevisiae mitochondria with ligands: Kinetics of CO and O2 binding to flavohemoglobin and cytochrome c oxidase.

Björck ML, Zhou S, Rydström Lundin C, Ott M, Ädelroth P, Brzezinski P.

Biochim Biophys Acta Bioenerg. 2017 Feb;1858(2):182-188. doi: 10.1016/j.bbabio.2016.11.009. Epub 2016 Nov 19.

18.

Isolation of yeast complex IV in native lipid nanodiscs.

Smirnova IA, Sjöstrand D, Li F, Björck M, Schäfer J, Östbye H, Högbom M, von Ballmoos C, Lander GC, Ädelroth P, Brzezinski P.

Biochim Biophys Acta. 2016 Dec;1858(12):2984-2992. doi: 10.1016/j.bbamem.2016.09.004. Epub 2016 Sep 13.

19.

Rapid Electron Transfer within the III-IV Supercomplex in Corynebacterium glutamicum.

Graf S, Fedotovskaya O, Kao WC, Hunte C, Ädelroth P, Bott M, von Ballmoos C, Brzezinski P.

Sci Rep. 2016 Sep 29;6:34098. doi: 10.1038/srep34098.

20.

Regulatory role of the respiratory supercomplex factors in Saccharomyces cerevisiae.

Rydström Lundin C, von Ballmoos C, Ott M, Ädelroth P, Brzezinski P.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4476-85. doi: 10.1073/pnas.1601196113. Epub 2016 Jul 18.

21.

Lipid-mediated Protein-protein Interactions Modulate Respiration-driven ATP Synthesis.

Nilsson T, Lundin CR, Nordlund G, Ädelroth P, von Ballmoos C, Brzezinski P.

Sci Rep. 2016 Apr 11;6:24113. doi: 10.1038/srep24113.

22.

Investigating the Proton Donor in the NO Reductase from Paracoccus denitrificans.

ter Beek J, Krause N, Ädelroth P.

PLoS One. 2016 Mar 31;11(3):e0152745. doi: 10.1371/journal.pone.0152745. eCollection 2016. Erratum in: PLoS One. 2016;11(5):e0155365.

23.

The two transmembrane helices of CcoP are sufficient for assembly of the cbb3-type heme-copper oxygen reductase from Vibrio cholerae.

Ahn YO, Lee HJ, Kaluka D, Yeh SR, Rousseau DL, Ädelroth P, Gennis RB.

Biochim Biophys Acta. 2015 Oct;1847(10):1231-9. doi: 10.1016/j.bbabio.2015.06.013. Epub 2015 Jun 25.

24.

Nitric oxide is a potent inhibitor of the cbb(3)-type heme-copper oxidases.

Arjona D, Wikström M, Ädelroth P.

FEBS Lett. 2015 May 8;589(11):1214-8. doi: 10.1016/j.febslet.2015.03.033. Epub 2015 Apr 8.

25.

Mutation of a single residue in the ba3 oxidase specifically impairs protonation of the pump site.

von Ballmoos C, Gonska N, Lachmann P, Gennis RB, Ädelroth P, Brzezinski P.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):3397-402. doi: 10.1073/pnas.1422434112. Epub 2015 Mar 2.

26.

Conformational coupling between the active site and residues within the K(C)-channel of the Vibrio cholerae cbb3-type (C-family) oxygen reductase.

Ahn YO, Mahinthichaichan P, Lee HJ, Ouyang H, Kaluka D, Yeh SR, Arjona D, Rousseau DL, Tajkhorshid E, Adelroth P, Gennis RB.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4419-28. doi: 10.1073/pnas.1411676111. Epub 2014 Oct 6.

27.

The nitric-oxide reductase from Paracoccus denitrificans uses a single specific proton pathway.

ter Beek J, Krause N, Reimann J, Lachmann P, Ädelroth P.

J Biol Chem. 2013 Oct 18;288(42):30626-35. doi: 10.1074/jbc.M113.497347. Epub 2013 Sep 6.

28.

Single mutations that redirect internal proton transfer in the ba3 oxidase from Thermus thermophilus.

Smirnova I, Chang HY, von Ballmoos C, Ädelroth P, Gennis RB, Brzezinski P.

Biochemistry. 2013 Oct 8;52(40):7022-30. doi: 10.1021/bi4008726. Epub 2013 Sep 23.

29.

Intermediates generated during the reaction of reduced Rhodobacter sphaeroides cytochrome c oxidase with dioxygen.

Brzezinski P, Ojemyr LN, Adelroth P.

Biochim Biophys Acta. 2013 Jul;1827(7):843-7. doi: 10.1016/j.bbabio.2013.04.007. Epub 2013 Apr 30. Review.

30.

The heme-copper oxidase superfamily shares a Zn2+-binding motif at the entrance to a proton pathway.

Lee HJ, Ädelroth P.

FEBS Lett. 2013 Mar 18;587(6):770-4. doi: 10.1016/j.febslet.2013.01.069. Epub 2013 Feb 8.

31.

Timing of electron and proton transfer in the ba(3) cytochrome c oxidase from Thermus thermophilus.

von Ballmoos C, Lachmann P, Gennis RB, Ädelroth P, Brzezinski P.

Biochemistry. 2012 Jun 5;51(22):4507-17. Epub 2012 May 24.

PMID:
22624600
32.

Proton transfer in the quinol-dependent nitric oxide reductase from Geobacillus stearothermophilus during reduction of oxygen.

Salomonsson L, Reimann J, Tosha T, Krause N, Gonska N, Shiro Y, Adelroth P.

Biochim Biophys Acta. 2012 Oct;1817(10):1914-20. doi: 10.1016/j.bbabio.2012.04.007. Epub 2012 Apr 17.

33.

Proton transfer in ba(3) cytochrome c oxidase from Thermus thermophilus.

von Ballmoos C, Adelroth P, Gennis RB, Brzezinski P.

Biochim Biophys Acta. 2012 Apr;1817(4):650-7. doi: 10.1016/j.bbabio.2011.11.015. Epub 2011 Dec 7. Review.

34.

Functional proton transfer pathways in the heme-copper oxidase superfamily.

Lee HJ, Reimann J, Huang Y, Adelroth P.

Biochim Biophys Acta. 2012 Apr;1817(4):537-44. doi: 10.1016/j.bbabio.2011.10.007. Epub 2011 Oct 26. Review.

35.

Entrance of the proton pathway in cbb3-type heme-copper oxidases.

Lee HJ, Gennis RB, Ädelroth P.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17661-6. doi: 10.1073/pnas.1107543108. Epub 2011 Oct 12.

36.

Kinetic design of the respiratory oxidases.

von Ballmoos C, Gennis RB, Ädelroth P, Brzezinski P.

Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11057-62. doi: 10.1073/pnas.1104103108. Epub 2011 Jun 20.

37.

Functional role of Thr-312 and Thr-315 in the proton-transfer pathway in ba3 Cytochrome c oxidase from Thermus thermophilus.

Smirnova I, Reimann J, von Ballmoos C, Chang HY, Gennis RB, Fee JA, Brzezinski P, Adelroth P.

Biochemistry. 2010 Aug 24;49(33):7033-9. doi: 10.1021/bi100749p.

38.

Substrate control of internal electron transfer in bacterial nitric-oxide reductase.

Lachmann P, Huang Y, Reimann J, Flock U, Adelroth P.

J Biol Chem. 2010 Aug 13;285(33):25531-7. doi: 10.1074/jbc.M110.123984. Epub 2010 Jun 11.

39.

Substrate binding and the catalytic reactions in cbb3-type oxidases: the lipid membrane modulates ligand binding.

Huang Y, Reimann J, Singh LM, Adelroth P.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):724-31. doi: 10.1016/j.bbabio.2010.03.016. Epub 2010 Mar 20.

40.

Exploring the terminal region of the proton pathway in the bacterial nitric oxide reductase.

Flock U, Lachmann P, Reimann J, Watmough NJ, Adelroth P.

J Inorg Biochem. 2009 May;103(5):845-50. doi: 10.1016/j.jinorgbio.2009.02.008. Epub 2009 Mar 3.

PMID:
19332356
41.

Vectorial proton transfer coupled to reduction of O2 and NO by a heme-copper oxidase.

Huang Y, Reimann J, Lepp H, Drici N, Adelroth P.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20257-62. doi: 10.1073/pnas.0805429106. Epub 2008 Dec 11.

42.

Molecular architecture of the proton diode of cytochrome c oxidase.

Brzezinski P, Reimann J, Adelroth P.

Biochem Soc Trans. 2008 Dec;36(Pt 6):1169-74. doi: 10.1042/BST0361169. Review.

PMID:
19021518
43.

Defining the proton entry point in the bacterial respiratory nitric-oxide reductase.

Flock U, Thorndycroft FH, Matorin AD, Richardson DJ, Watmough NJ, Adelroth P.

J Biol Chem. 2008 Feb 15;283(7):3839-45. Epub 2007 Dec 3.

44.

A pathway for protons in nitric oxide reductase from Paracoccus denitrificans.

Reimann J, Flock U, Lepp H, Honigmann A, Adelroth P.

Biochim Biophys Acta. 2007 May;1767(5):362-73. Epub 2007 Mar 16.

45.

Special issue on proton transfer in biological systems.

Adelroth P.

Biochim Biophys Acta. 2006 Aug;1757(8):867-70. No abstract available.

46.

Design principles of proton-pumping haem-copper oxidases.

Brzezinski P, Adelroth P.

Curr Opin Struct Biol. 2006 Aug;16(4):465-72. Epub 2006 Jul 13. Review.

PMID:
16842995
47.

Surface proton donors for the D-pathway of cytochrome c oxidase in the absence of subunit III.

Adelroth P, Hosler J.

Biochemistry. 2006 Jul 11;45(27):8308-18.

PMID:
16819830
48.

Inhibition of proton pumping by zinc ions during specific reaction steps in cytochrome c oxidase.

Faxén K, Salomonsson L, Adelroth P, Brzezinski P.

Biochim Biophys Acta. 2006 May-Jun;1757(5-6):388-94. Epub 2006 May 13.

49.

Proton transfer in bacterial nitric oxide reductase.

Flock U, Reimann J, Adelroth P.

Biochem Soc Trans. 2006 Feb;34(Pt 1):188-90. Review.

PMID:
16417518
50.

The timing of proton migration in membrane-reconstituted cytochrome c oxidase.

Salomonsson L, Faxén K, Adelroth P, Brzezinski P.

Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17624-9. Epub 2005 Nov 23.

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