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Items: 16

1.

Concentration-QT Modeling Following Inhalation of the Novel Inhaled Phosphodiesterase-4 Inhibitor CHF6001 in Healthy Volunteers Shows an Absence of QT Prolongation.

Jolling K, Äbelö A, Luyckx N, Nandeuil MA, Govoni M, Cella M, Lindauer A.

CPT Pharmacometrics Syst Pharmacol. 2019 Jul;8(7):460-468. doi: 10.1002/psp4.12405. Epub 2019 May 11.

2.

Simultaneous quantification of four first line antitubercular drugs and metabolites in human plasma by hydrophilic interaction chromatography and tandem mass spectrometry.

Sundell J, Bienvenu E, Birgersson S, Äbelö A, Ashton M, Hoffmann KJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Jan 15;1105:129-135. doi: 10.1016/j.jchromb.2018.10.027. Epub 2018 Oct 31.

PMID:
30584977
3.

Population pharmacokinetics of a three-day chloroquine treatment in patients with Plasmodium vivax infection on the Thai-Myanmar border.

Höglund R, Moussavi Y, Ruengweerayut R, Cheomung A, Äbelö A, Na-Bangchang K.

Malar J. 2016 Feb 29;15:129. doi: 10.1186/s12936-016-1181-1.

4.

Population pharmacokinetic properties of artemisinin in healthy male Vietnamese volunteers.

Birgersson S, Van Toi P, Truong NT, Dung NT, Ashton M, Hien TT, Abelö A, Tarning J.

Malar J. 2016 Feb 16;15:90. doi: 10.1186/s12936-016-1134-8.

5.

Artemether-lumefantrine co-administration with antiretrovirals: population pharmacokinetics and dosing implications.

Hoglund RM, Byakika-Kibwika P, Lamorde M, Merry C, Ashton M, Hanpithakpong W, Day NP, White NJ, Äbelö A, Tarning J.

Br J Clin Pharmacol. 2015 Apr;79(4):636-49. doi: 10.1111/bcp.12529.

6.

Population pharmacokinetics of artesunate and dihydroartemisinin during long-term oral administration of artesunate to patients with metastatic breast cancer.

Ericsson T, Blank A, von Hagens C, Ashton M, Äbelö A.

Eur J Clin Pharmacol. 2014 Dec;70(12):1453-63. doi: 10.1007/s00228-014-1754-2. Epub 2014 Sep 25.

PMID:
25248945
7.

The evaluation of CYP2B6 inhibition by artemisinin antimalarials in recombinant enzymes and human liver microsomes.

Ericsson T, Masimirembwa C, Abelo A, Ashton M.

Drug Metab Lett. 2012;6(4):247-57.

PMID:
23506555
8.

Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat.

Johansson CC, Gennemark P, Artursson P, Äbelö A, Ashton M, Jansson-Löfmark R.

J Pharmacokinet Pharmacodyn. 2013 Feb;40(1):117-28. doi: 10.1007/s10928-012-9293-x. Epub 2013 Jan 10.

PMID:
23307171
9.

External validation of the bilirubin-atazanavir nomogram for assessment of atazanavir plasma exposure in HIV-1-infected patients.

Rekić D, Röshammar D, Bergstrand M, Tarning J, Calcagno A, D'Avolio A, Ormaasen V, Vigan M, Barrail-Tran A, Ashton M, Gisslén M, Äbelö A.

AAPS J. 2013 Apr;15(2):308-15. doi: 10.1208/s12248-012-9440-8. Epub 2012 Dec 7.

10.

Bilirubin-a potential marker of drug exposure in atazanavir-based antiretroviral therapy.

Rekić D, Clewe O, Röshammar D, Flamholc L, Sönnerborg A, Ormaasen V, Gisslén M, Abelö A, Ashton M.

AAPS J. 2011 Dec;13(4):598-605. doi: 10.1208/s12248-011-9299-0. Epub 2011 Sep 13.

11.
12.

Gastric acid secretion in the dog: a mechanism-based pharmacodynamic model for histamine stimulation and irreversible inhibition by omeprazole.

Abelö A, Holstein B, Eriksson UG, Gabrielsson J, Karlsson MO.

J Pharmacokinet Pharmacodyn. 2002 Aug;29(4):365-82.

PMID:
12518709
13.

Pharmacodynamic modelling of reversible gastric acid pump inhibition in dog and man.

Abelö A, Gabrielsson J, Holstein B, Eriksson UG, Holmberg J, Karlsson MO.

Eur J Pharm Sci. 2001 Dec;14(4):339-46.

PMID:
11684409
14.

A turnover model of irreversible inhibition of gastric acid secretion by omeprazole in the dog.

Abelö A, Eriksson UG, Karlsson MO, Larsson H, Gabrielsson J.

J Pharmacol Exp Ther. 2000 Nov;295(2):662-9.

PMID:
11046103
15.

Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes.

Abelö A, Andersson TB, Antonsson M, Naudot AK, Skånberg I, Weidolf L.

Drug Metab Dispos. 2000 Aug;28(8):966-72.

PMID:
10901708
16.

Stereoselective metabolism by human liver CYP enzymes of a substituted benzimidazole.

Abelö A, Andersson TB, Bredberg U, Skånberg I, Weidolf L.

Drug Metab Dispos. 2000 Jan;28(1):58-64.

PMID:
10611141

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