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Page 1
Neuromuscular block: Monitoring, reversal, and residual blockade in small animals.
Martin-Flores M. Martin-Flores M. Vet Ophthalmol. 2023 May 29. doi: 10.1111/vop.13112. Online ahead of print. Vet Ophthalmol. 2023. PMID: 37248035 Review.
Nondepolarizing neuromuscular blocking agents are used frequently during ophthalmic surgery of dogs and cats. Residual neuromuscular block (NMB)-impaired neuromuscular function at recovery from anesthesia-is a main concern when these agen …
Nondepolarizing neuromuscular blocking agents are used frequently during ophthalmic surgery of dogs and cats. Residual …
Reversal of profound rocuronium or vecuronium-induced neuromuscular block with sugammadex in isoflurane-anaesthetised dogs.
Mosing M, Auer U, West E, Jones RS, Hunter JM. Mosing M, et al. Vet J. 2012 Jun;192(3):467-71. doi: 10.1016/j.tvjl.2011.08.034. Epub 2011 Oct 24. Vet J. 2012. PMID: 22030475 Clinical Trial.
This study evaluated the use of sugammadex for reversal of profound neuromuscular blockade induced with rocuronium or vecuronium in dogs. ...After both rocuronium and vecuronium blockade, T4/T1 recovered to 0.9 in under 2 min after sugammadex (58.1 67.8s and …
This study evaluated the use of sugammadex for reversal of profound neuromuscular blockade induced with rocuronium or vecuroni …
Reversal of atracurium neuromuscular block with neostigmine in the dog.
Jones RS. Jones RS. Res Vet Sci. 1990 Jan;48(1):96-8. Res Vet Sci. 1990. PMID: 2300723
A dose response relationship and the time of onset to 50 per cent and 100 per cent peak action were investigated for neostigmine reversal of atracurium in the dog. Two levels of neuromuscular block were used, 10 per cent and 50 per cent of the first tw …
A dose response relationship and the time of onset to 50 per cent and 100 per cent peak action were investigated for neostigmine reversal …
Neuromuscular blocking action of vecuronium in the dog and its reversal by neostigmine.
Jones RS. Jones RS. Res Vet Sci. 1985 Mar;38(2):193-6. Res Vet Sci. 1985. PMID: 2860709
Vecuronium bromide is one of a new series of competitive or nondepolarising muscle relaxants which is closely related chemically to pancuronium. Doses of 0.06, 0.1 and 0.2 mg kg-1 produced neuromuscular block in the anaesthetised dog. There were no observable …
Vecuronium bromide is one of a new series of competitive or nondepolarising muscle relaxants which is closely related chemically to pancuron …
Speed of reversal of vecuronium neuromuscular block with different doses of neostigmine in anesthetized dogs.
Martin-Flores M, Lorenzutti AM, Litterio NJ, Rossetti VL, Zarazaga MP, Bonetto CC, Aguirre GE. Martin-Flores M, et al. Vet Anaesth Analg. 2017 Jan;44(1):28-34. doi: 10.1111/vaa.12395. Epub 2017 Feb 23. Vet Anaesth Analg. 2017. PMID: 27258375 Clinical Trial.
This study was designed to measure the speed of reversal of vecuronium-induced neuromuscular block in isoflurane-anesthetized dogs after the administration of three doses of neostigmine as used in clinical practice. ...CONCLUSIONS AND CLINICAL RELEVANC …
This study was designed to measure the speed of reversal of vecuronium-induced neuromuscular block in isoflurane-anesth …
Neuromuscular blocking action of atracurium in the dog and its reversal by neostigmine.
Jones RS, Hunter JM, Utting JE. Jones RS, et al. Res Vet Sci. 1983 Mar;34(2):173-6. Res Vet Sci. 1983. PMID: 6687951
The drug, atracurium besylate is one of a new series of competitive muscle relaxants. Doses of 0.2, 0.4 and 0.6 mg/kg produced neuromuscular block in the anaesthetised dog with no cardiovascular effects. The neuromuscular block was readily re …
The drug, atracurium besylate is one of a new series of competitive muscle relaxants. Doses of 0.2, 0.4 and 0.6 mg/kg produced neuromuscu …
Observations on the neuromuscular blocking action of alcuronium in the dog and its reversal by neostigmine.
Jones RS, Heckmann R, Wuersch W. Jones RS, et al. Res Vet Sci. 1978 Jul;25(1):101-2. Res Vet Sci. 1978. PMID: 212797
The action of alcuronium chloride on neuromuscular transmission in the dogs was investigated by electrical and mechanical methods. The mean duration of action was 70 min. Reversal of its action was produced with atropine and neostigmine....
The action of alcuronium chloride on neuromuscular transmission in the dogs was investigated by electrical and mechanical meth …
Effects of two levels of partial neuromuscular block with atracurium on the ventilatory response to hypercapnia in anesthetized Beagles.
Sakai DM, Martin-Flores M. Sakai DM, et al. Am J Vet Res. 2018 Sep;79(9):915-920. doi: 10.2460/ajvr.79.9.915. Am J Vet Res. 2018. PMID: 30153055 Free article.
OBJECTIVE To evaluate effects of 2 levels of partial neuromuscular block on the ventilatory response to a hypercapnic challenge in anesthetized dogs and to evaluate effects of edrophonium for reversing partial neuromuscular block. ...All …
OBJECTIVE To evaluate effects of 2 levels of partial neuromuscular block on the ventilatory response to a hypercapnic challeng …
Effects of neostigmine or edrophonium on force of contraction when administered at a train-of-four ratio of 0.9 in anesthetized dogs.
Romano M, Martin-Flores M, Sakai DM, Tseng CT, Campoy L, Gleed RD. Romano M, et al. Vet Anaesth Analg. 2017 Nov;44(6):1313-1320. doi: 10.1016/j.vaa.2017.07.001. Epub 2017 Aug 3. Vet Anaesth Analg. 2017. PMID: 29066245 Clinical Trial.
OBJECTIVE: Anticholinesterase drugs may produce paradoxical neuromuscular block when administered at shallow levels of neuromuscular block. ...Although the clinical implications are uncertain, the results suggest that, at these doses, edrophonium may b …
OBJECTIVE: Anticholinesterase drugs may produce paradoxical neuromuscular block when administered at shallow levels of neur …
Cardiovascular and autonomic nervous effects of edrophonium and atropine combinations during neuromuscular blockade antagonism in sheep.
Clutton RE, Glasby MA. Clutton RE, et al. Vet Anaesth Analg. 2008 May;35(3):191-200. doi: 10.1111/j.1467-2995.2007.00374.x. Epub 2008 Feb 18. Vet Anaesth Analg. 2008. PMID: 18282258 Clinical Trial.

Data were analysed using one-way within-subjects and repeated measures anova. RESULTS: In the first study, all combinations reversed NMB but significantly (p < 0.001) increased HR and BP within 2 minutes without arrhythmias. ...Administered first, atropine (80 microg kg

…
Data were analysed using one-way within-subjects and repeated measures anova. RESULTS: In the first study, all combinations reversed …
47 results