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Items: 1 to 20 of 160


Exosomal miRNAs species in the blood of small cell and non-small cell lung cancer patients.

Poroyko V, Mirzapoiazova T, Nam A, Mambetsariev I, Mambetsariev B, Wu X, Husain A, Vokes EE, Wheeler DL, Salgia R.

Oncotarget. 2018 Apr 13;9(28):19793-19806. doi: 10.18632/oncotarget.24857. eCollection 2018 Apr 13.


Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses.

Athmer J, Fehr AR, Grunewald ME, Qu W, Wheeler DL, Graepel KW, Channappanavar R, Sekine A, Aldabeeb DS, Gale M Jr, Denison MR, Perlman S.

MBio. 2018 May 1;9(3). pii: e00272-18. doi: 10.1128/mBio.00272-18.


RNAi drives nonreciprocal translocations at eroding chromosome ends to establish telomere-free linear chromosomes.

Begnis M, Apte MS, Masuda H, Jain D, Wheeler DL, Cooper JP.

Genes Dev. 2018 Apr 1;32(7-8):537-554. doi: 10.1101/gad.311712.118. Epub 2018 Apr 13.


On-Site Molecular Detection of Soil-Borne Phytopathogens Using a Portable Real-Time PCR System.

DeShields JB, Bomberger RA, Woodhall JW, Wheeler DL, Moroz N, Johnson DA, Tanaka K.

J Vis Exp. 2018 Feb 23;(132). doi: 10.3791/56891.


Microglia are required for protection against lethal coronavirus encephalitis in mice.

Wheeler DL, Sariol A, Meyerholz DK, Perlman S.

J Clin Invest. 2018 Mar 1;128(3):931-943. doi: 10.1172/JCI97229. Epub 2018 Jan 29.


Anti-Trop2 blockade enhances the therapeutic efficacy of ErbB3 inhibition in head and neck squamous cell carcinoma.

Redlich N, Robinson AM, Nickel KP, Stein AP, Wheeler DL, Adkins DR, Uppaluri R, Kimple RJ, Van Tine BA, Michel LS.

Cell Death Dis. 2018 Jan 5;9(1):5. doi: 10.1038/s41419-017-0029-0.


Akt1 and Akt3 but not Akt2 through interaction with DNA-PKcs stimulate proliferation and post-irradiation cell survival of K-RAS-mutated cancer cells.

Toulany M, Maier J, Iida M, Rebholz S, Holler M, Grottke A, J√ľker M, Wheeler DL, Rothbauer U, Rodemann HP.

Cell Death Discov. 2017 Oct 30;3:17072. doi: 10.1038/cddiscovery.2017.72. eCollection 2017.


Overcoming Resistance to Cetuximab with Honokiol, A Small-Molecule Polyphenol.

Pearson HE, Iida M, Orbuch RA, McDaniel NK, Nickel KP, Kimple RJ, Arbiser JL, Wheeler DL.

Mol Cancer Ther. 2018 Jan;17(1):204-214. doi: 10.1158/1535-7163.MCT-17-0384. Epub 2017 Oct 20.


Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus.

Wheeler DL, Athmer J, Meyerholz DK, Perlman S.

J Virol. 2017 Aug 23. pii: JVI.01099-17. doi: 10.1128/JVI.01099-17. [Epub ahead of print]


Barriers to Access and Adoption of Pre-Exposure Prophylaxis for the Prevention of HIV Among Men Who Have Sex With Men (MSM) in a Relatively Rural State.

Hubach RD, Currin JM, Sanders CA, Durham AR, Kavanaugh KE, Wheeler DL, Croff JM.

AIDS Educ Prev. 2017 Aug;29(4):315-329. doi: 10.1521/aeap.2017.29.4.315.


Modeling electrochromic poly-dioxythiophene-containing materials through TDDFT.

Wheeler DL, Rainwater LE, Green AR, Tomlinson AL.

Phys Chem Chem Phys. 2017 Aug 2;19(30):20251-20258. doi: 10.1039/c7cp04130f.


Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling.

Vijay R, Fehr AR, Janowski AM, Athmer J, Wheeler DL, Grunewald M, Sompallae R, Kurup SP, Meyerholz DK, Sutterwala FS, Narumiya S, Perlman S.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):E5444-E5453. doi: 10.1073/pnas.1704099114. Epub 2017 Jun 19.


Preparing Physicians for Rural-Based Primary Care Practice: A Preliminary Evaluation of Rural Training Initiatives at OSU-COM.

Wheeler DL, Hackler JB.

J Am Osteopath Assoc. 2017 May 1;117(5):315-324. doi: 10.7556/jaoa.2017.057.


Cotargeting mTORC and EGFR Signaling as a Therapeutic Strategy in HNSCC.

Swick AD, Prabakaran PJ, Miller MC, Javaid AM, Fisher MM, Sampene E, Ong IM, Hu R, Iida M, Nickel KP, Bruce JY, Wheeler DL, Kimple RJ.

Mol Cancer Ther. 2017 Jul;16(7):1257-1268. doi: 10.1158/1535-7163.MCT-17-0115. Epub 2017 Apr 26.


The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.

Brand TM, Iida M, Corrigan KL, Braverman CM, Coan JP, Flanigan BG, Stein AP, Salgia R, Rolff J, Kimple RJ, Wheeler DL.

Sci Signal. 2017 Jan 3;10(460). pii: eaag1064. doi: 10.1126/scisignal.aag1064.


Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.

Iida M, Bahrar H, Brand TM, Pearson HE, Coan JP, Orbuch RA, Flanigan BG, Swick AD, Prabakaran PJ, Lantto J, Horak ID, Kragh M, Salgia R, Kimple RJ, Wheeler DL.

Mol Cancer Ther. 2016 Sep;15(9):2175-86. doi: 10.1158/1535-7163.MCT-16-0012. Epub 2016 Jul 15.


Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer.

Toulany M, Iida M, Keinath S, Iyi FF, Mueck K, Fehrenbacher B, Mansour WY, Schaller M, Wheeler DL, Rodemann HP.

Oncotarget. 2016 Jul 12;7(28):43746-43761. doi: 10.18632/oncotarget.9670.


Feedback regulation of biological networks: Examples relevant to signalling pathways and resistance to pharmacological interceptors.

Yarden Y, Wheeler DL.

Semin Cell Dev Biol. 2016 Feb;50:83-4. doi: 10.1016/j.semcdb.2016.02.016. No abstract available.


Verticillium dahliae Infects, Alters Plant Biomass, and Produces Inoculum on Rotation Crops.

Wheeler DL, Johnson DA.

Phytopathology. 2016 Jun;106(6):602-13. doi: 10.1094/PHYTO-07-15-0174-R. Epub 2016 Apr 8.


Adaptive responses to antibody based therapy.

Rodems TS, Iida M, Brand TM, Pearson HE, Orbuch RA, Flanigan BG, Wheeler DL.

Semin Cell Dev Biol. 2016 Feb;50:153-63. doi: 10.1016/j.semcdb.2016.01.001. Epub 2016 Jan 22. Review.


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