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Items: 1 to 20 of 176

1.

Suicide gene‑armed measles vaccine virus for the treatment of AML.

Maurer S, Salih HR, Smirnow I, Lauer UM, Berchtold S.

Int J Oncol. 2019 Aug;55(2):347-358. doi: 10.3892/ijo.2019.4835. Epub 2019 Jul 2.

2.

Isocytosine deaminase Vcz as a novel tool for the prodrug cancer therapy.

Kazlauskas A, Darinskas A, Meškys R, Tamašauskas A, Urbonavičius J.

BMC Cancer. 2019 Mar 4;19(1):197. doi: 10.1186/s12885-019-5409-7.

3.

Photochemical Internalization Enhanced Nonviral Suicide Gene Therapy.

Sun CH, Berg K, Hirschberg H.

Methods Mol Biol. 2019;1895:165-176. doi: 10.1007/978-1-4939-8922-5_13.

4.

Prodrug suicide gene therapy for cancer targeted intracellular by mesenchymal stem cell exosomes.

Altanerova U, Jakubechova J, Benejova K, Priscakova P, Pesta M, Pitule P, Topolcan O, Kausitz J, Zduriencikova M, Repiska V, Altaner C.

Int J Cancer. 2019 Feb 15;144(4):897-908. doi: 10.1002/ijc.31792. Epub 2018 Sep 27.

PMID:
30098225
5.

Insight into the recognition mechanism of DNA cytosine-5 methyltransferases (DNMTs) by incorporation of acyclic 5-fluorocytosine (FC) nucleosides into DNA.

Utsumi S, Sato K, Ichikawa S.

Bioorg Med Chem Lett. 2018 Jul 1;28(12):2189-2194. doi: 10.1016/j.bmcl.2018.05.008. Epub 2018 May 5.

PMID:
29752184
6.

Simultaneous detection of 5-fluorocytosine and 5-fluorouracil in human cells carrying CD/5-FC suicide gene system by using capillary zone electrophoresis.

Liu Y, Zhu P, Huang Z, Zhou L, Shi P.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Feb 15;1076:1-7. doi: 10.1016/j.jchromb.2018.01.011. Epub 2018 Jan 7.

PMID:
29353670
7.

Expression of Therapeutic Gene FCU1 Sensitizes Pancreatic Cancer Cells to 5-Fluorocytosine and Enhances the Cytotoxic Effect of 5-Fluorouracil.

Kopantsev EP, Kostina MB, Grankina EV, Kopantseva MR, Egorov VI, Sverdlov ED.

Bull Exp Biol Med. 2016 Oct;161(6):808-810. Epub 2016 Oct 26.

PMID:
27783293
8.

Marker recycling via 5-fluoroorotic acid and 5-fluorocytosine counter-selection in the white-rot agaricomycete Pleurotus ostreatus.

Nakazawa T, Tsuzuki M, Irie T, Sakamoto M, Honda Y.

Fungal Biol. 2016 Sep;120(9):1146-55. doi: 10.1016/j.funbio.2016.06.011. Epub 2016 Jul 2.

PMID:
27567720
9.

Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma.

Cloughesy TF, Landolfi J, Hogan DJ, Bloomfield S, Carter B, Chen CC, Elder JB, Kalkanis SN, Kesari S, Lai A, Lee IY, Liau LM, Mikkelsen T, Nghiemphu PL, Piccioni D, Walbert T, Chu A, Das A, Diago OR, Gammon D, Gruber HE, Hanna M, Jolly DJ, Kasahara N, McCarthy D, Mitchell L, Ostertag D, Robbins JM, Rodriguez-Aguirre M, Vogelbaum MA.

Sci Transl Med. 2016 Jun 1;8(341):341ra75. doi: 10.1126/scitranslmed.aad9784.

10.

PSMA-specific theranostic nanoplex for combination of TRAIL gene and 5-FC prodrug therapy of prostate cancer.

Chen Z, Penet MF, Krishnamachary B, Banerjee SR, Pomper MG, Bhujwalla ZM.

Biomaterials. 2016 Feb;80:57-67. doi: 10.1016/j.biomaterials.2015.11.048. Epub 2015 Dec 2.

11.

Enhanced EJ Cell Killing of (125)I Radiation by Combining with Cytosine Deaminase Gene Therapy Regulated by Synthetic Radio-Responsive Promoter.

Li L, Zhang CL, Kang L, Wang RF, Yan P, Zhao Q, Yin L, Guo FQ.

Cancer Biother Radiopharm. 2015 Oct;30(8):342-8. doi: 10.1089/cbr.2015.1862. Epub 2015 Sep 18.

12.

Annexin V-Directed Enzyme Prodrug Therapy Plus Docetaxel for the Targeted Treatment of Pancreatic Cancer.

Guillen KP, Restuccia A, Kurkjian C, Harrison RG.

Pancreas. 2015 Aug;44(6):945-52. doi: 10.1097/MPA.0000000000000343.

PMID:
25899647
13.

Discovery of a bacterial 5-methylcytosine deaminase.

Hitchcock DS, Fedorov AA, Fedorov EV, Almo SC, Raushel FM.

Biochemistry. 2014 Dec 2;53(47):7426-35. doi: 10.1021/bi5012767. Epub 2014 Nov 19.

14.

Gene delivery in malignant B cells using the combination of lentiviruses conjugated to anti-transferrin receptor antibodies and an immunoglobulin promoter.

Leoh LS, Morizono K, Kershaw KM, Chen IS, Penichet ML, Daniels-Wells TR.

J Gene Med. 2014 Jan-Feb;16(1-2):11-27. doi: 10.1002/jgm.2754.

15.

Oncosuppressive suicide gene virotherapy "PVH1-yCD/5-FC" for pancreatic peritoneal carcinomatosis treatment: NFκB and Akt/PI3K involvement.

Réjiba S, Bigand C, Parmentier C, Masmoudi A, Hajri A.

PLoS One. 2013 Aug 14;8(8):e70594. doi: 10.1371/journal.pone.0070594. eCollection 2013.

16.

Adenosine potentiates the therapeutic effects of neural stem cells expressing cytosine deaminase against metastatic brain tumors.

Kang W, Seol HJ, Seong DH, Kim J, Kim Y, Kim SU, Nam DH, Joo KM.

Oncol Rep. 2013 Sep;30(3):1101-6. doi: 10.3892/or.2013.2584. Epub 2013 Jul 3.

PMID:
23828015
17.

Pancreatic tumor mass in a xenograft mouse model is decreased by treatment with therapeutic stem cells following introduction of therapeutic genes.

Kim DJ, Yi BR, Lee HR, Kim SU, Choi KC.

Oncol Rep. 2013 Sep;30(3):1129-36. doi: 10.3892/or.2013.2564. Epub 2013 Jun 25.

PMID:
23807450
18.

[Antitumor activity of the recombinant rClone30-CD/5-FC system].

Lu Z, Zhang TY, Han MM, Bai FL, Wu W, Tian GY, Ren GP, Li DS.

Yao Xue Xue Bao. 2013 Feb;48(2):261-8. Chinese.

PMID:
23672024
19.

Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies.

Aboody KS, Najbauer J, Metz MZ, D'Apuzzo M, Gutova M, Annala AJ, Synold TW, Couture LA, Blanchard S, Moats RA, Garcia E, Aramburo S, Valenzuela VV, Frank RT, Barish ME, Brown CE, Kim SU, Badie B, Portnow J.

Sci Transl Med. 2013 May 8;5(184):184ra59. doi: 10.1126/scitranslmed.3005365.

20.

Chemovirotherapy of malignant melanoma with a targeted and armed oncolytic measles virus.

Kaufmann JK, Bossow S, Grossardt C, Sawall S, Kupsch J, Erbs P, Hassel JC, von Kalle C, Enk AH, Nettelbeck DM, Ungerechts G.

J Invest Dermatol. 2013 Apr;133(4):1034-42. doi: 10.1038/jid.2012.459. Epub 2012 Dec 6.

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