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Items: 1 to 20 of 46

1.

Molecular Analyses Support the Safety and Activity of Retroviral Replicating Vector Toca 511 in Patients.

Hogan DJ, Zhu JJ, Diago OR, Gammon D, Haghighi A, Lu G, Das A, Gruber HE, Jolly DJ, Ostertag D.

Clin Cancer Res. 2018 Oct 1;24(19):4680-4693. doi: 10.1158/1078-0432.CCR-18-0619. Epub 2018 Jun 26.

2.

Insight into the recognition mechanism of DNA cytosine-5 methyltransferases (DNMTs) by incorporation of acyclic 5-fluorocytosine (FC) nucleosides into DNA.

Utsumi S, Sato K, Ichikawa S.

Bioorg Med Chem Lett. 2018 Jul 1;28(12):2189-2194. doi: 10.1016/j.bmcl.2018.05.008. Epub 2018 May 5.

PMID:
29752184
3.

Novel potentially antifungal hybrids of 5-flucytosine and fluconazole: Design, synthesis and bioactive evaluation.

Fang XF, Li D, Tangadanchu VKR, Gopala L, Gao WW, Zhou CH.

Bioorg Med Chem Lett. 2017 Nov 15;27(22):4964-4969. doi: 10.1016/j.bmcl.2017.10.020. Epub 2017 Oct 13.

PMID:
29050784
4.

Flucytosine analogues obtained through Biginelli reaction as efficient combinative antifungal agents.

Wani MY, Ahmad A, Kumar S, Sobral AJ.

Microb Pathog. 2017 Apr;105:57-62. doi: 10.1016/j.micpath.2017.02.006. Epub 2017 Feb 9.

PMID:
28189732
5.

Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases.

Olszewska A, Dadová J, Mačková M, Hocek M.

Bioorg Med Chem. 2015 Nov 1;23(21):6885-90. doi: 10.1016/j.bmc.2015.09.051. Epub 2015 Oct 14.

PMID:
26463367
6.

Bioactive Core-Shell Nanofiber Hybrid Scaffold for Efficient Suicide Gene Transfection and Subsequent Time Resolved Delivery of Prodrug for Anticancer Therapy.

Sukumar UK, Packirisamy G.

ACS Appl Mater Interfaces. 2015 Aug 26;7(33):18717-31. doi: 10.1021/acsami.5b05280. Epub 2015 Aug 11.

PMID:
26234345
7.

Quantum chemical investigations on the nonradiative deactivation pathways of cytosine derivatives.

Nakayama A, Yamazaki S, Taketsugu T.

J Phys Chem A. 2014 Oct 9;118(40):9429-37. doi: 10.1021/jp506740r. Epub 2014 Sep 17.

PMID:
25178384
8.

Versatile types of polysaccharide-based supramolecular polycation/pDNA nanoplexes for gene delivery.

Hu Y, Zhao N, Yu B, Liu F, Xu FJ.

Nanoscale. 2014 Jul 7;6(13):7560-9. doi: 10.1039/c4nr01590h.

PMID:
24890703
9.

Near-IR-induced, UV-induced, and spontaneous isomerizations in 5-methylcytosine and 5-fluorocytosine.

Lapinski L, Reva I, Rostkowska H, Fausto R, Nowak MJ.

J Phys Chem B. 2014 Mar 20;118(11):2831-41. doi: 10.1021/jp411423c. Epub 2014 Mar 6.

PMID:
24559084
10.

Excited-state structure, vibrations, and nonradiative relaxation of jet-cooled 5-fluorocytosine.

Lobsiger S, Trachsel MA, Den T, Leutwyler S.

J Phys Chem B. 2014 Mar 20;118(11):2973-84. doi: 10.1021/jp500410s. Epub 2014 Mar 6.

PMID:
24559066
11.

Enabling tablet product development of 5-fluorocytosine through integrated crystal and particle engineering.

Perumalla SR, Sun CC.

J Pharm Sci. 2014 Apr;103(4):1126-32. doi: 10.1002/jps.23876. Epub 2014 Feb 11.

PMID:
24515970
12.

Design, synthesis, and characterization of new 5-fluorocytosine salts.

Perumalla SR, Pedireddi VR, Sun CC.

Mol Pharm. 2013 Jun 3;10(6):2462-6. doi: 10.1021/mp400070a. Epub 2013 May 22.

PMID:
23631720
13.

Comparison of MICs of fluconazole and flucytosine when dissolved in dimethyl sulfoxide or water.

Fothergill AW, Sanders C, Wiederhold NP.

J Clin Microbiol. 2013 Jun;51(6):1955-7. doi: 10.1128/JCM.00260-13. Epub 2013 Apr 10.

14.

Synthesis of cyclopentanyl carbocyclic 5-fluorocytosine ((-)-5-fluorocarbodine) using a facially selective hydrogenation approach.

Cho JH, Amblard F, Coats SJ, Schinazi RF.

J Org Chem. 2013 Jan 18;78(2):723-7. doi: 10.1021/jo302038d. Epub 2012 Dec 26.

15.
16.

Cocrystals of 5-fluorocytosine. II. Coformers with variable hydrogen-bonding sites.

Tutughamiarso M, Egert E.

Acta Crystallogr B. 2012 Aug;68(Pt 4):444-52. doi: 10.1107/S0108768112029977. Epub 2012 Jul 17.

PMID:
22810914
17.

Cocrystals of 5-fluorocytosine. I. Coformers with fixed hydrogen-bonding sites.

Tutughamiarso M, Wagner G, Egert E.

Acta Crystallogr B. 2012 Aug;68(Pt 4):431-43. doi: 10.1107/S010876811202561X. Epub 2012 Jul 17.

PMID:
22810913
18.

Synthesis and cytotoxic activity of 4-N-carboxybutyl-5-fluorocytosyl-Arg-Gln-Trp-Arg-Arg-Trp-Trp-Gln-Arg-NH₂.

Somlai C, Correche E, Olivella M, Tolosa L, Lechon MJ, Dombi G, Tóth GK, Penke B, Enriz RD.

Bioorg Med Chem Lett. 2012 Jul 1;22(13):4233-7. doi: 10.1016/j.bmcl.2012.05.045. Epub 2012 May 17.

PMID:
22658365
19.

Role of glutamate 64 in the activation of the prodrug 5-fluorocytosine by yeast cytosine deaminase.

Wang J, Sklenak S, Liu A, Felczak K, Wu Y, Li Y, Yan H.

Biochemistry. 2012 Jan 10;51(1):475-86. doi: 10.1021/bi201540z. Epub 2011 Dec 29.

20.

Creation of bioorthogonal redox systems depending on nicotinamide flucytosine dinucleotide.

Ji D, Wang L, Hou S, Liu W, Wang J, Wang Q, Zhao ZK.

J Am Chem Soc. 2011 Dec 28;133(51):20857-62. doi: 10.1021/ja2074032. Epub 2011 Dec 6.

PMID:
22098020

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