[Genetic risk factors of osteoporosis--vitamin D receptor gene polymorphism]

Agnieszka Seremak-Mrozikiewicz; Krzysztof Drews

[Genetic risk factors of osteoporosis--vitamin D receptor gene polymorphism]

Ginekol Pol. 2004 May;75(5):404-11.

[Article in Polish]

Authors

Agnieszka Seremak-Mrozikiewicz¹, Krzysztof Drews

Affiliation

¹ Klinika Perinatologii, Akademii Medycznej w Poznaniu.

PMID: 15524415

Abstract

The aetiology of osteoporosis is not fully understood but it was suggested that the genetic factors could play an important role. The many studies have presented the key role of the polymorphism of the gene encoding for vitamin D receptor (VDR). The modern concepts about VDR and osteoporosis were summarised in this review.

Publication types

English Abstract
Review

MeSH terms

Adult
Alleles
Bone Density / genetics*
Deoxyribonucleases, Type II Site-Specific / genetics
Female
Genetic Predisposition to Disease
Humans
Middle Aged
Osteoporosis, Postmenopausal / genetics*
Osteoporosis, Postmenopausal / metabolism
Polymorphism, Genetic*
Postmenopause / genetics*
Receptors, Calcitriol / genetics*
Receptors, Calcitriol / metabolism
Risk Factors

Substances

Receptors, Calcitriol
endodeoxyribonuclease BsmI
Deoxyribonucleases, Type II Site-Specific