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Squamous Cell Transformation of Primary Lung Adenocarcinoma in a Patient With EML4-ALK Fusion Variant 5 Refractory to ALK Inhibitors.

Gong J, Gregg JP, Ma W, Yoneda K, Moore EH, Daly ME, Zhang Y, Williams MJ, Li T.

J Natl Compr Canc Netw. 2019 Apr 1;17(4):297-301. doi: 10.6004/jnccn.2019.7291.


Phase II Trial of Cabozantinib Plus Erlotinib in Patients With Advanced Epidermal Growth Factor Receptor (EGFR)-Mutant Non-small Cell Lung Cancer With Progressive Disease on Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy: A California Cancer Consortium Phase II Trial (NCI 9303).

Reckamp KL, Frankel PH, Ruel N, Mack PC, Gitlitz BJ, Li T, Koczywas M, Gadgeel SM, Cristea MC, Belani CP, Newman EM, Gandara DR, Lara PN Jr.

Front Oncol. 2019 Mar 11;9:132. doi: 10.3389/fonc.2019.00132. eCollection 2019.


Isolation of 11,12- seco-Rifamycin W Derivatives Reveals a Cleavage Pattern of the Rifamycin Ansa Chain.

Shi Y, Zhang J, Tian X, Wu X, Li T, Lu C, Shen Y.

Org Lett. 2019 Feb 15;21(4):900-903. doi: 10.1021/acs.orglett.8b03792. Epub 2019 Feb 4.


Ensartinib (X-396): what does it add for patients with ALK-rearranged NSCLC.

Li T, Ma W, Tian EC.

Chin Clin Oncol. 2018 Nov 9. pii: cco.2018.10.12. doi: 10.21037/cco.2018.10.12. [Epub ahead of print] No abstract available.


Sortilin as a new membrane inhibitor of EGFR trafficking for overcoming resistance to EGFR inhibitors in non-small cell lung cancer.

Li Q, Ma W, Li T.

J Thorac Dis. 2018 Sep;10(Suppl 26):S3186-S3191. doi: 10.21037/jtd.2018.08.25. No abstract available.


Investigation on the Antibacterial and Anti-T3SS Activity of Traditional Myanmar Medicinal Plants.

Li T, Zhang D, Oo TN, San MM, Mon AM, Hein PP, Wang Y, Lu C, Yang X.

Evid Based Complement Alternat Med. 2018 Oct 9;2018:2812908. doi: 10.1155/2018/2812908. eCollection 2018.


Clinical utility of tumor genomic profiling in patients with high plasma circulating tumor DNA burden or metabolically active tumors.

Zhou C, Yuan Z, Ma W, Qi L, Mahavongtrakul A, Li Y, Li H, Gong J, Fan RR, Li J, Molmen M, Clark TA, Pavlick D, Frampton GM, Forcier B, Moore EH, Shelton DK, Cooke M, Ali SM, Miller VA, Gregg JP, Stephens PJ, Li T.

J Hematol Oncol. 2018 Nov 6;11(1):129. doi: 10.1186/s13045-018-0671-8.


Hybrid Capture-Based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Non-Small Cell Lung Cancer.

Schrock AB, Welsh A, Chung JH, Pavlick D, Bernicker EH, Creelan BC, Forcier B, Ross JS, Stephens PJ, Ali SM, Dagogo-Jack I, Shaw AT, Li T, Ou SI, Miller VA.

J Thorac Oncol. 2019 Feb;14(2):255-264. doi: 10.1016/j.jtho.2018.10.008. Epub 2018 Oct 24.


Transcriptomic analysis of light-dependent anthocyanin accumulation in bicolored cherry fruits.

Guo X, Wang Y, Zhai Z, Huang T, Zhao D, Peng X, Feng C, Xiao Y, Li T.

Plant Physiol Biochem. 2018 Sep;130:663-677. doi: 10.1016/j.plaphy.2018.08.016. Epub 2018 Aug 9.


Targeted Discovery and Combinatorial Biosynthesis of Polycyclic Tetramate Macrolactam Combamides A-E.

Liu Y, Wang H, Song R, Chen J, Li T, Li Y, Du L, Shen Y.

Org Lett. 2018 Jun 15;20(12):3504-3508. doi: 10.1021/acs.orglett.8b01285. Epub 2018 May 24.


The Tsinghua-Lancet Commission on Healthy Cities in China: unlocking the power of cities for a healthy China.

Yang J, Siri JG, Remais JV, Cheng Q, Zhang H, Chan KKY, Sun Z, Zhao Y, Cong N, Li X, Zhang W, Bai Y, Bi J, Cai W, Chan EYY, Chen W, Fan W, Fu H, He J, Huang H, Ji JS, Jia P, Jiang X, Kwan MP, Li T, Li X, Liang S, Liang X, Liang L, Liu Q, Lu Y, Luo Y, Ma X, Schwartländer B, Shen Z, Shi P, Su J, Wu T, Yang C, Yin Y, Zhang Q, Zhang Y, Zhang Y, Xu B, Gong P.

Lancet. 2018 May 26;391(10135):2140-2184. doi: 10.1016/S0140-6736(18)30486-0. Epub 2018 Apr 17. Review. No abstract available.


Src activation decouples cell division orientation from cell geometry in mammalian cells.

Sun X, Qi H, Zhang X, Li L, Zhang J, Zeng Q, Laszlo GS, Wei B, Li T, Jiang J, Mogilner A, Fu X, Zhao M.

Biomaterials. 2018 Jul;170:82-94. doi: 10.1016/j.biomaterials.2018.03.052. Epub 2018 Apr 3.


An ethylene response factor (MxERF4) functions as a repressor of Fe acquisition in Malus xiaojinensis.

Liu W, Wu T, Li Q, Zhang X, Xu X, Li T, Han Z, Wang Y.

Sci Rep. 2018 Jan 18;8(1):1068. doi: 10.1038/s41598-018-19518-4.


Cloning and expression profiling of the PacSnRK2 and PacPP2C gene families during fruit development, ABA treatment, and dehydration stress in sweet cherry.

Shen X, Guo X, Zhao D, Zhang Q, Jiang Y, Wang Y, Peng X, Wei Y, Zhai Z, Zhao W, Li T.

Plant Physiol Biochem. 2017 Oct;119:275-285. doi: 10.1016/j.plaphy.2017.08.025. Epub 2017 Sep 6.


Durable Local Control Following Concurrent Hypofractionated Chemoradiation for a Massive Inflammatory Breast Cancer Chest Wall Recurrence.

Dyer BA, Nguyen KNB, Shukla RP, Li T, Daly ME.

Cureus. 2017 Jun 21;9(6):e1379. doi: 10.7759/cureus.1379.


Small RNA-Sequencing Links Physiological Changes and RdDM Process to Vegetative-to-Floral Transition in Apple.

Guo X, Ma Z, Zhang Z, Cheng L, Zhang X, Li T.

Front Plant Sci. 2017 May 29;8:873. doi: 10.3389/fpls.2017.00873. eCollection 2017.


Conversion Discriminative Analysis on Mild Cognitive Impairment Using Multiple Cortical Features from MR Images.

Guo S, Lai C, Wu C, Cen G; Alzheimer's Disease Neuroimaging Initiative.

Front Aging Neurosci. 2017 May 18;9:146. doi: 10.3389/fnagi.2017.00146. eCollection 2017. Erratum in: Front Aging Neurosci. 2017 Sep 05;9:293.


Spatial disparity dynamics of ecosystem service values and GDP in Shaanxi Province, China in the last 30 years.

Li T, Ding Y.

PLoS One. 2017 Mar 30;12(3):e0174562. doi: 10.1371/journal.pone.0174562. eCollection 2017.


KETCH1 imports HYL1 to nucleus for miRNA biogenesis in Arabidopsis.

Zhang Z, Guo X, Ge C, Ma Z, Jiang M, Li T, Koiwa H, Yang SW, Zhang X.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):4011-4016. doi: 10.1073/pnas.1619755114. Epub 2017 Mar 27.


Severe nivolumab-induced pneumonitis preceding durable clinical remission in a patient with refractory, metastatic lung squamous cell cancer: a case report.

Li H, Ma W, Yoneda KY, Moore EH, Zhang Y, Pu LL, Frampton GM, Molmen M, Stephens PJ, Li T.

J Hematol Oncol. 2017 Feb 28;10(1):64. doi: 10.1186/s13045-017-0433-z.


PacMYBA, a sweet cherry R2R3-MYB transcription factor, is a positive regulator of salt stress tolerance and pathogen resistance.

Shen X, Guo X, Guo X, Zhao D, Zhao W, Chen J, Li T.

Plant Physiol Biochem. 2017 Mar;112:302-311. doi: 10.1016/j.plaphy.2017.01.015. Epub 2017 Jan 17.


Evolution and Increasing Complexity of the Therapeutic Landscape in Advanced Non-Small-cell Lung Cancer.

Gandara DR, Riess JW, Kelly K, Li T, Mack PC, Lara PN Jr.

Clin Lung Cancer. 2017 Jan;18(1):1-4. doi: 10.1016/j.cllc.2016.12.011. Epub 2016 Dec 24.


Randomized Phase 2 Trial of Pharmacodynamic Separation of Pemetrexed and Intercalated Erlotinib Versus Pemetrexed Alone for Advanced Nonsquamous, Non-small-cell Lung Cancer.

Li T, Piperdi B, Walsh WV, Kim M, Beckett LA, Gucalp R, Haigentz M Jr, Bathini VG, Wen H, Zhou K, Pasquinelli PB, Gajavelli S, Sreedhara M, Xie X, Lara PN Jr, Gandara DR, Perez-Soler R.

Clin Lung Cancer. 2017 Jan;18(1):60-67. doi: 10.1016/j.cllc.2016.10.003. Epub 2016 Oct 28.


Overexpression of MsDREB6.2 results in cytokinin-deficient developmental phenotypes and enhances drought tolerance in transgenic apple plants.

Liao X, Guo X, Wang Q, Wang Y, Zhao D, Yao L, Wang S, Liu G, Li T.

Plant J. 2017 Feb;89(3):510-526. doi: 10.1111/tpj.13401. Epub 2017 Feb 1.


Disulfide-crosslinked nanomicelles confer cancer-specific drug delivery and improve efficacy of paclitaxel in bladder cancer.

Pan A, Zhang H, Li Y, Lin TY, Wang F, Lee J, Cheng M, Dall'Era M, Li T, deVere White R, Pan CX, Lam KS.

Nanotechnology. 2016 Oct 21;27(42):425103. doi: 10.1088/0957-4484/27/42/425103. Epub 2016 Sep 19.


Novel theranostic nanoporphyrins for photodynamic diagnosis and trimodal therapy for bladder cancer.

Lin TY, Li Y, Liu Q, Chen JL, Zhang H, Lac D, Zhang H, Ferrara KW, Wachsmann-Hogiu S, Li T, Airhart S, deVere White R, Lam KS, Pan CX.

Biomaterials. 2016 Oct;104:339-51. doi: 10.1016/j.biomaterials.2016.07.026. Epub 2016 Jul 22.


Lateral transport of soil carbon and land-atmosphere CO2 flux induced by water erosion in China.

Yue Y, Ni J, Ciais P, Piao S, Wang T, Huang M, Borthwick AG, Li T, Wang Y, Chappell A, Van Oost K.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6617-22. doi: 10.1073/pnas.1523358113. Epub 2016 May 31.


Current status and perspectives in translational biomarker research for PD-1/PD-L1 immune checkpoint blockade therapy.

Ma W, Gilligan BM, Yuan J, Li T.

J Hematol Oncol. 2016 May 27;9(1):47. doi: 10.1186/s13045-016-0277-y. Review.


First-in-human, open-label dose-escalation and dose-expansion study of the safety, pharmacokinetics, and antitumor effects of an oral ALK inhibitor ASP3026 in patients with advanced solid tumors.

Li T, LoRusso P, Maitland ML, Ou SH, Bahceci E, Ball HA, Park JW, Yuen G, Tolcher A.

J Hematol Oncol. 2016 Mar 10;9:23. doi: 10.1186/s13045-016-0254-5.


Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors.

Xiao W, Li T, Bononi FC, Lac D, Kekessie IA, Liu Y, Sanchez E, Mazloom A, Ma AH, Lin J, Tran J, Yang K, Lam KS, Liu R.

EJNMMI Res. 2016 Dec;6(1):18. doi: 10.1186/s13550-016-0165-z. Epub 2016 Feb 27.


Phase II Study of the AKT Inhibitor MK-2206 plus Erlotinib in Patients with Advanced Non-Small Cell Lung Cancer Who Previously Progressed on Erlotinib.

Lara PN Jr, Longmate J, Mack PC, Kelly K, Socinski MA, Salgia R, Gitlitz B, Li T, Koczywas M, Reckamp KL, Gandara DR.

Clin Cancer Res. 2015 Oct 1;21(19):4321-6. doi: 10.1158/1078-0432.CCR-14-3281. Epub 2015 Jun 23.


Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization.

Wang WP, Ho PY, Chen QX, Addepalli B, Limbach PA, Li MM, Wu WJ, Jilek JL, Qiu JX, Zhang HJ, Li T, Wun T, White RD, Lam KS, Yu AM.

J Pharmacol Exp Ther. 2015 Aug;354(2):131-41. doi: 10.1124/jpet.115.225631. Epub 2015 May 28.


The Cloning and Functional Characterization of Peach CONSTANS and FLOWERING LOCUS T Homologous Genes PpCO and PpFT.

Zhang X, An L, Nguyen TH, Liang H, Wang R, Liu X, Li T, Qi Y, Yu F.

PLoS One. 2015 Apr 23;10(4):e0124108. doi: 10.1371/journal.pone.0124108. eCollection 2015.


Bridging tumor genomics to patient outcomes through an integrated patient-derived xenograft platform.

Gandara DR, Mack PC, Bult C, Li T, Lara PN Jr, Riess JW, Astrow SH, Gandour-Edwards R, Cooke DT, Yoneda KY, Moore EH, Pan CX, Burich RA, David EA, Keck JG, Airhart S, Goodwin N, de Vere White RW, Liu ET.

Clin Lung Cancer. 2015 May;16(3):165-72. doi: 10.1016/j.cllc.2015.03.001. Epub 2015 Mar 18.


Spatiotemporal sequestration of miR165/166 by Arabidopsis Argonaute10 promotes shoot apical meristem maintenance.

Zhou Y, Honda M, Zhu H, Zhang Z, Guo X, Li T, Li Z, Peng X, Nakajima K, Duan L, Zhang X.

Cell Rep. 2015 Mar 24;10(11):1819-27.


Phase I Trial of Arginine Deprivation Therapy with ADI-PEG 20 Plus Docetaxel in Patients with Advanced Malignant Solid Tumors.

Tomlinson BK, Thomson JA, Bomalaski JS, Diaz M, Akande T, Mahaffey N, Li T, Dutia MP, Kelly K, Gong IY, Semrad T, Gandara DR, Pan CX, Lara PN Jr.

Clin Cancer Res. 2015 Jun 1;21(11):2480-6. doi: 10.1158/1078-0432.CCR-14-2610. Epub 2015 Mar 4.


A role for PacMYBA in ABA-regulated anthocyanin biosynthesis in red-colored sweet cherry cv. Hong Deng (Prunus avium L.).

Shen X, Zhao K, Liu L, Zhang K, Yuan H, Liao X, Wang Q, Guo X, Li F, Li T.

Plant Cell Physiol. 2014 May;55(5):862-80. doi: 10.1093/pcp/pcu013. Epub 2014 Jan 18.


Large-scale screening and molecular characterization of EML4-ALK fusion variants in archival non-small-cell lung cancer tumor specimens using quantitative reverse transcription polymerase chain reaction assays.

Li T, Maus MK, Desai SJ, Beckett LA, Stephens C, Huang E, Hsiang J, Zeger G, Danenberg KD, Astrow SH, Gandara DR.

J Thorac Oncol. 2014 Jan;9(1):18-25. doi: 10.1097/JTO.0000000000000030.


Acquired resistance to targeted therapies against oncogene-driven non-small-cell lung cancer: approach to subtyping progressive disease and clinical implications.

Gandara DR, Li T, Lara PN, Kelly K, Riess JW, Redman MW, Mack PC.

Clin Lung Cancer. 2014 Jan;15(1):1-6. doi: 10.1016/j.cllc.2013.10.001. Epub 2013 Oct 12.


Retraction: The phosphatase inhibitor menadione (vitamin K3) protects cells from EGFR inhibition by erlotinib and cetuximab.

Perez-Soler R, Zou Y, Li T, Ling YH.

Clin Cancer Res. 2013 Sep 1;19(17):4901. doi: 10.1158/1078-0432.CCR-13-1912. No abstract available.


CTEN prolongs signaling by EGFR through reducing its ligand-induced degradation.

Hong SY, Shih YP, Li T, Carraway KL 3rd, Lo SH.

Cancer Res. 2013 Aug 15;73(16):5266-76. doi: 10.1158/0008-5472.CAN-12-4441. Epub 2013 Jun 17.


Isolation and characterization of dehydration-responsive element-binding factor 2C (MsDREB2C) from Malus sieversii Roem.

Zhao K, Shen X, Yuan H, Liu Y, Liao X, Wang Q, Liu L, Li F, Li T.

Plant Cell Physiol. 2013 Sep;54(9):1415-30. doi: 10.1093/pcp/pct087. Epub 2013 Jun 11. Erratum in: Plant Cell Physiol. 2013 Oct;54(10):1749.


Genome-wide analysis of the GH3 family in apple (Malus × domestica).

Yuan H, Zhao K, Lei H, Shen X, Liu Y, Liao X, Li T.

BMC Genomics. 2013 May 2;14:297. doi: 10.1186/1471-2164-14-297.


Histology-related associations of ERCC1, RRM1, and TS biomarkers in patients with non-small-cell lung cancer: implications for therapy.

Maus MK, Mack PC, Astrow SH, Stephens CL, Zeger GD, Grimminger PP, Hsiang JH, Huang E, Li T, Lara PN, Danenberg KD, Gandara DR.

J Thorac Oncol. 2013 May;8(5):582-6. doi: 10.1097/JTO.0b013e318287c3c5.


Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies.

Li T, Kung HJ, Mack PC, Gandara DR.

J Clin Oncol. 2013 Mar 10;31(8):1039-49. doi: 10.1200/JCO.2012.45.3753. Epub 2013 Feb 11. Review.


A novel β-glucosidase from Aspergillus fumigates releases diosgenin from spirostanosides of Dioscorea zingiberensis C. H. Wright (DZW).

Lei J, Niu H, Li T, Huang W.

World J Microbiol Biotechnol. 2012 Mar;28(3):1309-14. doi: 10.1007/s11274-011-0907-z. Epub 2011 Nov 19.


Algorithm for codevelopment of new drug-predictive biomarker combinations: accounting for inter- and intrapatient tumor heterogeneity.

Gandara DR, Li T, Lara PN Jr, Mack PC, Kelly K, Miyamoto S, Goodwin N, Beckett L, Redman MW.

Clin Lung Cancer. 2012 Sep;13(5):321-5. doi: 10.1016/j.cllc.2012.05.004. Epub 2012 Jun 6. No abstract available.


A phase II trial of capecitabine in combination with the farnesyltransferase inhibitor tipifarnib in patients with anthracycline-treated and taxane-resistant metastatic breast cancer: an Eastern Cooperative Oncology Group Study (E1103).

Li T, Guo M, Gradishar WJ, Sparano JA, Perez EA, Wang M, Sledge GW.

Breast Cancer Res Treat. 2012 Jul;134(1):345-52. doi: 10.1007/s10549-012-2071-z. Epub 2012 May 1.


Comparative study of phenolic compounds and antioxidant activity in different species of cherries.

Liu Y, Liu X, Zhong F, Tian R, Zhang K, Zhang X, Li T.

J Food Sci. 2011 May;76(4):C633-8. doi: 10.1111/j.1750-3841.2011.02150.x. Epub 2011 Apr 14.


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