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Items: 29


Understanding the Role of Androgen Action in Female Adipose Tissue.

Schiffer L, Arlt W, O'Reilly MW.

Front Horm Res. 2019;53:33-49. doi: 10.1159/000494901. Epub 2019 Sep 9.


Natural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess: A Systematic Review and Meta-analysis.

Elhassan YS, Alahdab F, Prete A, Delivanis DA, Khanna A, Prokop L, Murad MH, O'Reilly MW, Arlt W, Bancos I.

Ann Intern Med. 2019 Jul 16;171(2):107-116. doi: 10.7326/M18-3630. Epub 2019 Jun 25.


Increased risk of obstructive sleep apnoea in women with polycystic ovary syndrome: a population-based cohort study.

Balachandran K, Sumilo D, O'Reilly MW, Toulis KA, Gokhale K, Wijeyaratne C, Coomarasamy A, Arlt W, Tahrani A, Nirantharakumar K.

Eur J Endocrinol. 2019 Feb 1. pii: EJE-18-0693.R2. doi: 10.1530/EJE-18-0693. [Epub ahead of print]


A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics.

O'Reilly MW, Westgate CS, Hornby C, Botfield H, Taylor AE, Markey K, Mitchell JL, Scotton WJ, Mollan SP, Yiangou A, Jenkinson C, Gilligan LC, Sherlock M, Gibney J, Tomlinson JW, Lavery GG, Hodson DJ, Arlt W, Sinclair AJ.

JCI Insight. 2019 Mar 21;4(6). pii: 125348. doi: 10.1172/jci.insight.125348. eCollection 2019 Mar 21.


Causes, patterns and severity of androgen excess in 487 consecutively recruited pre- and post-pubertal children.

Idkowiak J, Elhassan YS, Mannion P, Smith K, Webster R, Saraff V, Barrett TG, Shaw NJ, Krone N, Dias RP, Kershaw M, Kirk JM, Högler W, Krone RE, O'Reilly MW, Arlt W.

Eur J Endocrinol. 2019 Mar 1;180(3):213-221. doi: 10.1530/EJE-18-0854.


Serum testosterone, sex hormone-binding globulin and sex-specific risk of incident type 2 diabetes in a retrospective primary care cohort.

O'Reilly MW, Glisic M, Kumarendran B, Subramanian A, Manolopoulos KN, Tahrani AA, Keerthy D, Muka T, Toulis KA, Hanif W, Thomas GN, Franco OH, Arlt W, Nirantharakumar K.

Clin Endocrinol (Oxf). 2019 Jan;90(1):145-154. doi: 10.1111/cen.13862. Epub 2018 Oct 23.


Metabolic Concepts in Idiopathic Intracranial Hypertension and Their Potential for Therapeutic Intervention.

Hornby C, Mollan SP, Botfield H, OʼReilly MW, Sinclair AJ.

J Neuroophthalmol. 2018 Dec;38(4):522-530. doi: 10.1097/WNO.0000000000000684.


Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: A longitudinal study based on a United Kingdom primary care database.

Kumarendran B, O'Reilly MW, Manolopoulos KN, Toulis KA, Gokhale KM, Sitch AJ, Wijeyaratne CN, Coomarasamy A, Arlt W, Nirantharakumar K.

PLoS Med. 2018 Mar 28;15(3):e1002542. doi: 10.1371/journal.pmed.1002542. eCollection 2018 Mar.


Evaluating the Fat Distribution in Idiopathic Intracranial Hypertension Using Dual-Energy X-ray Absorptiometry Scanning.

Hornby C, Botfield H, O'Reilly MW, Westgate C, Mitchell J, Mollan SP, Manolopoulos K, Tomlinson J, Sinclair A.

Neuroophthalmology. 2017 Jun 20;42(2):99-104. doi: 10.1080/01658107.2017.1334218. eCollection 2018 Apr.


Causes, Patterns, and Severity of Androgen Excess in 1205 Consecutively Recruited Women.

Elhassan YS, Idkowiak J, Smith K, Asia M, Gleeson H, Webster R, Arlt W, O'Reilly MW.

J Clin Endocrinol Metab. 2018 Mar 1;103(3):1214-1223. doi: 10.1210/jc.2017-02426.


What Do Transgender Patients Teach Us About Idiopathic Intracranial Hypertension?

Hornby C, Mollan SP, Mitchell J, Markey KA, Yangou A, Wright BLC, O'Reilly MW, Sinclair AJ.

Neuroophthalmology. 2017 May 10;41(6):326-329. doi: 10.1080/01658107.2017.1316744. eCollection 2017.


AKR1C3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome.

O'Reilly MW, Kempegowda P, Walsh M, Taylor AE, Manolopoulos KN, Allwood JW, Semple RK, Hebenstreit D, Dunn WB, Tomlinson JW, Arlt W.

J Clin Endocrinol Metab. 2017 Sep 1;102(9):3327-3339. doi: 10.1210/jc.2017-00947.


MECHANISMS IN ENDOCRINOLOGY: The sexually dimorphic role of androgens in human metabolic disease.

Schiffer L, Kempegowda P, Arlt W, O'Reilly MW.

Eur J Endocrinol. 2017 Sep;177(3):R125-R143. doi: 10.1530/EJE-17-0124. Epub 2017 May 31. Review.


Diabetic ketoacidosis: a challenging diabetes phenotype.

Small C, Egan AM, Elhadi EM, O'Reilly MW, Cunningham A, Finucane FM.

Endocrinol Diabetes Metab Case Rep. 2017 Feb 28;2017. pii: 16-0109. doi: 10.1530/EDM-16-0109. eCollection 2017.


Outcome of Nonfunctioning Pituitary Adenomas That Regrow After Primary Treatment: A Study From Two Large UK Centers.

Tampourlou M, Ntali G, Ahmed S, Arlt W, Ayuk J, Byrne JV, Chavda S, Cudlip S, Gittoes N, Grossman A, Mitchell R, O'Reilly MW, Paluzzi A, Toogood A, Wass JAH, Karavitaki N.

J Clin Endocrinol Metab. 2017 Jun 1;102(6):1889-1897. doi: 10.1210/jc.2016-4061.


Acute Hypercortisolemia Exerts Depot-Specific Effects on Abdominal and Femoral Adipose Tissue Function.

Manolopoulos KN, O'Reilly MW, Bujalska IJ, Tomlinson JW, Arlt W.

J Clin Endocrinol Metab. 2017 Apr 1;102(4):1091-1101. doi: 10.1210/jc.2016-3600.


11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome.

O'Reilly MW, Kempegowda P, Jenkinson C, Taylor AE, Quanson JL, Storbeck KH, Arlt W.

J Clin Endocrinol Metab. 2017 Mar 1;102(3):840-848. doi: 10.1210/jc.2016-3285.


SFRP2 Is Associated with Increased Adiposity and VEGF Expression.

Crowley RK, O'Reilly MW, Bujalska IJ, Hassan-Smith ZK, Hazlehurst JM, Foucault DR, Stewart PM, Tomlinson JW.

PLoS One. 2016 Sep 29;11(9):e0163777. doi: 10.1371/journal.pone.0163777. eCollection 2016.


ACTH and gonadotropin deficiencies predict mortality in patients treated for nonfunctioning pituitary adenoma: long-term follow-up of 519 patients in two large European centres.

O'Reilly MW, Reulen RC, Gupta S, Thompson CA, Dineen R, Goulden EL, Bugg G, Pearce H, Toogood AA, Gittoes NJ, Mitchell R, Thompson CJ, Ayuk J.

Clin Endocrinol (Oxf). 2016 Nov;85(5):748-756. doi: 10.1111/cen.13141. Epub 2016 Jul 25.


Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome.

Gathercole LL, Hazlehurst JM, Armstrong MJ, Crowley R, Boocock S, O'Reilly MW, Round M, Brown R, Bolton S, Cramb R, Newsome PN, Semple RK, Paisey R, Tomlinson JW, Geberhiwot T.

Liver Int. 2016 Nov;36(11):1704-1712. doi: 10.1111/liv.13163. Epub 2016 Jun 10.


PAPSS2 deficiency causes androgen excess via impaired DHEA sulfation--in vitro and in vivo studies in a family harboring two novel PAPSS2 mutations.

Oostdijk W, Idkowiak J, Mueller JW, House PJ, Taylor AE, O'Reilly MW, Hughes BA, de Vries MC, Kant SG, Santen GW, Verkerk AJ, Uitterlinden AG, Wit JM, Losekoot M, Arlt W.

J Clin Endocrinol Metab. 2015 Apr;100(4):E672-80. doi: 10.1210/jc.2014-3556. Epub 2015 Jan 16.


Understanding androgen action in adipose tissue.

O'Reilly MW, House PJ, Tomlinson JW.

J Steroid Biochem Mol Biol. 2014 Sep;143:277-84. doi: 10.1016/j.jsbmb.2014.04.008. Epub 2014 Apr 28. Review.


Hyperandrogenemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione.

O'Reilly MW, Taylor AE, Crabtree NJ, Hughes BA, Capper F, Crowley RK, Stewart PM, Tomlinson JW, Arlt W.

J Clin Endocrinol Metab. 2014 Mar;99(3):1027-36. doi: 10.1210/jc.2013-3399. Epub 2014 Jan 1.


A comparative quality assessment of evidence-based clinical guidelines in endocrinology.

Hazlehurst JM, Armstrong MJ, Sherlock M, Rowe IA, O'Reilly MW, Franklyn JA, Stewart PM, Tomlinson JW.

Clin Endocrinol (Oxf). 2013 Feb;78(2):183-90. doi: 10.1111/j.1365-2265.2012.04441.x.


ATLANTIC-DIP: raised maternal body mass index (BMI) adversely affects maternal and fetal outcomes in glucose-tolerant women according to International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria.

Dennedy MC, Avalos G, O'Reilly MW, O'Sullivan EP, Gaffney G, Dunne F.

J Clin Endocrinol Metab. 2012 Apr;97(4):E608-12. doi: 10.1210/jc.2011-2674. Epub 2012 Feb 8.


Atlantic DIP: high prevalence of abnormal glucose tolerance post partum is reduced by breast-feeding in women with prior gestational diabetes mellitus.

O'Reilly MW, Avalos G, Dennedy MC, O'Sullivan EP, Dunne F.

Eur J Endocrinol. 2011 Dec;165(6):953-9. doi: 10.1530/EJE-11-0663. Epub 2011 Sep 21.


Specific PGF(2alpha) receptor (FP) antagonism and human uterine contractility in vitro.

Friel AM, O'Reilly MW, Sexton DJ, Morrison JJ.

BJOG. 2005 Aug;112(8):1034-42.


Functional effects of 17alpha-hydroxyprogesterone caproate (17P) on human myometrial contractility in vitro.

Sexton DJ, O'Reilly MW, Friel AM, Morrison JJ.

Reprod Biol Endocrinol. 2004 Dec 7;2:80.

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