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Items: 43

1.

THERAPY OF ENDOCRINE DISEASE: Growth hormone replacement therapy in adults: 30 years of personal clinical experience.

Jørgensen JOL, Juul A.

Eur J Endocrinol. 2018 Jul;179(1):R47-R56. doi: 10.1530/EJE-18-0306. Epub 2018 May 1. Review.

PMID:
29716978
2.

Growth Hormone Research Society perspective on biomarkers of GH action in children and adults.

Johannsson G, Bidlingmaier M, Biller BMK, Boguszewski M, Casanueva FF, Chanson P, Clayton PE, Choong CS, Clemmons D, Dattani M, Frystyk J, Ho K, Hoffman AR, Horikawa R, Juul A, Kopchick JJ, Luo X, Neggers S, Netchine I, Olsson DS, Radovick S, Rosenfeld R, Ross RJ, Schilbach K, Solberg P, Strasburger C, Trainer P, Yuen KCJ, Wickstrom K, Jorgensen JOL; Growth Hormone Research Society.

Endocr Connect. 2018 Mar;7(3):R126-R134. doi: 10.1530/EC-18-0047. Epub 2018 Feb 26. Review.

3.

Targeting either GH or IGF-I during somatostatin analogue treatment in patients with acromegaly: a randomized multicentre study.

Dal J, Klose M, Heck A, Andersen M, Kistorp C, Nielsen EH, Bollerslev J, Feldt-Rasmussen U, Jørgensen JOL.

Eur J Endocrinol. 2018 Jan;178(1):67-76. doi: 10.1530/EJE-17-0546. Epub 2017 Oct 9.

PMID:
28993415
4.

Substrate Metabolism and Insulin Sensitivity During Fasting in Obese Human Subjects: Impact of GH Blockade.

Pedersen MH, Svart MV, Lebeck J, Bidlingmaier M, Stødkilde-Jørgensen H, Pedersen SB, Møller N, Jessen N, Jørgensen JOL.

J Clin Endocrinol Metab. 2017 Apr 1;102(4):1340-1349. doi: 10.1210/jc.2016-3835.

PMID:
28324055
5.

Stress hormone release is a key component of the metabolic response to lipopolysaccharide: studies in hypopituitary and healthy subjects.

Bach E, Møller AB, Jørgensen JO, Vendelbo MH, Jessen N, Pedersen SB, Nielsen TS, Møller N.

Eur J Endocrinol. 2016 Nov;175(5):455-65. doi: 10.1530/EJE-16-0444. Epub 2016 Aug 25.

PMID:
27562403
6.

The solitary sellar plasmacytoma: a diagnostic challenge.

Soejbjerg A, Dyve S, Baerentzen S, Thorsell G, Poulsen PL, Jorgensen JO, Kampmann U.

Endocrinol Diabetes Metab Case Rep. 2016;2016:160031. doi: 10.1530/EDM-16-0031. Epub 2016 Jun 8.

7.

GH signaling in human adipose and muscle tissue during 'feast and famine': amplification of exercise stimulation following fasting compared to glucose administration.

Vendelbo MH, Christensen B, Grønbæk SB, Høgild M, Madsen M, Pedersen SB, Jørgensen JO, Jessen N, Møller N.

Eur J Endocrinol. 2015 Sep;173(3):283-90. doi: 10.1530/EJE-14-1157. Epub 2015 Jun 1.

PMID:
26034073
8.

Physical exercise increases autophagic signaling through ULK1 in human skeletal muscle.

Møller AB, Vendelbo MH, Christensen B, Clasen BF, Bak AM, Jørgensen JO, Møller N, Jessen N.

J Appl Physiol (1985). 2015 Apr 15;118(8):971-9. doi: 10.1152/japplphysiol.01116.2014. Epub 2015 Feb 12.

9.

An unusual case of an ACTH-secreting macroadenoma with a germline variant in the aryl hydrocarbon receptor-interacting protein (AIP) gene.

Dinesen PT, Dal J, Gabrovska P, Gaustadnes M, Gravholt CH, Stals K, Denes J, Asa SL, Korbonits M, Jørgensen JO.

Endocrinol Diabetes Metab Case Rep. 2015;2015:140105. doi: 10.1530/EDM-14-0105. Epub 2015 Jan 1.

10.

Circulating acylghrelin levels are suppressed by insulin and increase in response to hypoglycemia in healthy adult volunteers.

Lauritzen ES, Voss T, Kampmann U, Mengel A, Vendelbo MH, Jørgensen JO, Møller N, Vestergaard ET.

Eur J Endocrinol. 2015 Apr;172(4):357-62. doi: 10.1530/EJE-14-0880. Epub 2015 Jan 19.

PMID:
25599708
11.

Intact pituitary function is decisive for the catabolic response to TNF-α: studies of protein, glucose and fatty acid metabolism in hypopituitary and healthy subjects.

Bach E, Møller AB, Jørgensen JO, Vendelbo MH, Jessen N, Olesen JF, Pedersen SB, Nielsen TS, Møller N.

J Clin Endocrinol Metab. 2015 Feb;100(2):578-86. doi: 10.1210/jc.2014-2489. Epub 2014 Nov 6.

PMID:
25375979
12.

GH signaling in skeletal muscle and adipose tissue in healthy human subjects: impact of gender and age.

Vestergaard PF, Vendelbo MH, Pedersen SB, Juul A, Ringgard S, Møller N, Jessen N, Jørgensen JO.

Eur J Endocrinol. 2014 Nov;171(5):623-31. doi: 10.1530/EJE-14-0538. Epub 2014 Aug 27.

PMID:
25163724
13.

Giant prolactinoma presenting as a skull base tumor with erosion of the cervical vertebrae: pronounced responsiveness to dopamine agonist treatment.

Bjerg ML, Rosendal F, Nielsen E, Ulhøi BP, Jørgensen JO.

Br J Neurosurg. 2014 Aug 27:1-3. [Epub ahead of print]

PMID:
25162753
14.

Growth hormone signaling in muscle and adipose tissue of obese human subjects: associations with measures of body composition and interaction with resveratrol treatment.

Clasen BF, Poulsen MM, Escande C, Pedersen SB, Møller N, Chini EN, Jessen N, Jørgensen JO.

J Clin Endocrinol Metab. 2014 Dec;99(12):E2565-73. doi: 10.1210/jc.2014-2215.

PMID:
25050904
15.

Direct effects of TNF-α on local fuel metabolism and cytokine levels in the placebo-controlled, bilaterally infused human leg: increased insulin sensitivity, increased net protein breakdown, and increased IL-6 release.

Bach E, Nielsen RR, Vendelbo MH, Møller AB, Jessen N, Buhl M, K-Hafstrøm T, Holm L, Pedersen SB, Pilegaard H, Biensø RS, Jørgensen JO, Møller N.

Diabetes. 2013 Dec;62(12):4023-9. doi: 10.2337/db13-0138. Epub 2013 Jul 8.

16.

Direct effects of locally administered lipopolysaccharide on glucose, lipid, and protein metabolism in the placebo-controlled, bilaterally infused human leg.

Buhl M, Bosnjak E, Vendelbo MH, Gjedsted J, Nielsen RR, K-Hafstrøm T, Vestergaard ET, Jessen N, Tønnesen E, Møller AB, Pedersen SB, Pilegaard H, Biensø RS, Jørgensen JO, Møller N.

J Clin Endocrinol Metab. 2013 May;98(5):2090-9. doi: 10.1210/jc.2012-3836. Epub 2013 Mar 29.

PMID:
23543661
17.

Cotreatment with pegvisomant and a somatostatin analog (SA) in SA-responsive acromegalic patients.

Madsen M, Poulsen PL, Orskov H, Møller N, Jørgensen JO.

J Clin Endocrinol Metab. 2011 Aug;96(8):2405-13. doi: 10.1210/jc.2011-0654. Epub 2011 Jun 1.

PMID:
21632808
18.

Insulin and GH signaling in human skeletal muscle in vivo following exogenous GH exposure: impact of an oral glucose load.

Krusenstjerna-Hafstrøm T, Madsen M, Vendelbo MH, Pedersen SB, Christiansen JS, Møller N, Jessen N, Jørgensen JO.

PLoS One. 2011 May 3;6(5):e19392. doi: 10.1371/journal.pone.0019392.

19.

Hypothesis: Extra-hepatic acromegaly: a new paradigm?

Neggers SJ, Kopchick JJ, Jørgensen JO, van der Lely AJ.

Eur J Endocrinol. 2011 Jan;164(1):11-6. doi: 10.1530/EJE-10-0969. Epub 2010 Nov 2.

PMID:
21045065
20.

Hypersecretion of the alpha-subunit in clinically non-functioning pituitary adenomas: Diagnostic accuracy is improved by adding alpha-subunit/gonadotropin ratio to levels of alpha-subunit.

Andersen M, Ganc-Petersen J, Jørgensen JO, Mellemkjaer S, Petersen PH, Blaabjerg O, Hagen C.

Clin Invest Med. 2010 Jun 1;33(3):E203-12.

PMID:
20519100
21.

Discontinuation of hormone replacement therapy in young GH-treated hypopituitary women increases liver enzymes.

Høst C, Christiansen JJ, Christiansen JS, Jorgensen JO, Gravholt CH.

Growth Horm IGF Res. 2010 Feb;20(1):26-30. doi: 10.1016/j.ghir.2009.07.001. Epub 2009 Aug 5.

PMID:
19660970
22.

Peroxisome proliferator-activated receptor gamma (PPAR) agonism reduces the insulin-stimulated increase in circulating interleukin-6 in GH replaced GH-deficient adults.

Krag MB, Rasmussen LM, Hansen TK, Frystyk J, Flyvbjerg A, Møller N, Jørgensen JO.

Clin Endocrinol (Oxf). 2009 Sep;71(3):363-8. doi: 10.1111/j.1365-2265.2008.03483.x. Epub 2008 Dec 3.

PMID:
19067726
23.

Peroxisome proliferator-activated receptor gamma agonism modifies the effects of growth hormone on lipolysis and insulin sensitivity.

Krag MB, Nielsen S, Guo Z, Pedersen SB, Schmitz O, Christiansen JS, Jørgensen JO.

Clin Endocrinol (Oxf). 2008 Sep;69(3):452-61. doi: 10.1111/j.1365-2265.2008.03231.x. Epub 2008 Mar 10.

PMID:
18331610
24.

Fasting in healthy subjects is associated with intrahepatic accumulation of lipids as assessed by 1H-magnetic resonance spectroscopy.

Moller L, Stodkilde-Jorgensen H, Jensen FT, Jorgensen JO.

Clin Sci (Lond). 2008 Apr;114(8):547-52.

PMID:
17990983
25.

The impact of pegvisomant treatment on substrate metabolism and insulin sensitivity in patients with acromegaly.

Lindberg-Larsen R, Møller N, Schmitz O, Nielsen S, Andersen M, Orskov H, Jørgensen JO.

J Clin Endocrinol Metab. 2007 May;92(5):1724-8. Epub 2007 Mar 6.

PMID:
17341562
26.

Effects of growth hormone on glucose and fat metabolism in human subjects.

Jørgensen JO, Møller L, Krag M, Billestrup N, Christiansen JS.

Endocrinol Metab Clin North Am. 2007 Mar;36(1):75-87. Review.

PMID:
17336735
27.

Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics.

Krag MB, Gormsen LC, Guo Z, Christiansen JS, Jensen MD, Nielsen S, Jørgensen JO.

Am J Physiol Endocrinol Metab. 2007 Mar;292(3):E920-7. Epub 2006 Nov 28.

28.

GH receptor signaling in skeletal muscle and adipose tissue in human subjects following exposure to an intravenous GH bolus.

Jørgensen JO, Jessen N, Pedersen SB, Vestergaard E, Gormsen L, Lund SA, Billestrup N.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E899-905. Epub 2006 Jun 6.

29.

Sex steroids and the growth hormone/insulin-like growth factor-I axis in adults.

Jørgensen JO, Christensen JJ, Vestergaard E, Fisker S, Ovesen P, Christiansen JS.

Horm Res. 2005;64 Suppl 2:37-40.

PMID:
16286769
30.

Clinical aspects of growth hormone deficiency in adults. An overview.

Jørgensen JO, Christiansen JS.

Front Horm Res. 2005;33:1-20. Review. No abstract available.

PMID:
16166752
31.

Somatropin and glucose homeostasis: considerations for patient management.

Jørgensen JO, Nørrelund H, Conceicao F, Møller N, Christiansen JS.

Treat Endocrinol. 2002;1(4):229-34. Review.

PMID:
15799216
32.

Serum insulin-like growth factor I levels in growth hormone-deficient adults: influence of sex steroids.

Jørgensen JO, Christensen JJ, Krag M, Fisker S, Ovesen P, Christiansen JS.

Horm Res. 2004;62 Suppl 1:73-6. Review.

PMID:
15761236
33.

Growth hormone and glucose homeostasis.

Jørgensen JO, Krag M, Jessen N, Nørrelund H, Vestergaard ET, Møller N, Christiansen JS.

Horm Res. 2004;62 Suppl 3:51-5. Review.

PMID:
15539799
34.

Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.

Jessen N, Djurhuus CB, Jørgensen JO, Jensen LS, Møller N, Lund S, Schmitz O.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E194-9. Epub 2004 Aug 31.

35.

Growth hormone receptor expression and function in pituitary adenomas.

Clausen LR, Kristiansen MT, Rasmussen LM, Billestrup N, Blaabjerg O, Ledet T, Jørgensen JO.

Clin Endocrinol (Oxf). 2004 May;60(5):576-83.

PMID:
15104560
36.

Dehydroepiandrosterone supplementation in women with adrenal failure: impact on twenty-four hour GH secretion and IGF-related parameters.

Christiansen JJ, Gravholt CH, Fisker S, Svenstrup B, Bennett P, Veldhuis J, Andersen M, Christiansen JS, Jørgensen JO.

Clin Endocrinol (Oxf). 2004 Apr;60(4):461-9.

PMID:
15049961
37.

Continuation of growth hormone therapy versus placebo in transition-phase patients with growth hormone deficiency: impact on body composition, insulin sensitivity, and thyroid function.

Jørgensen JO, Nørrelund H, Vahl N, Juul A, Skakkebaek NE, Christiansen JS.

J Pediatr Endocrinol Metab. 2002 Dec;15 Suppl 5:1355-60.

PMID:
12510991
38.

Effects of lowering circulating free fatty acid levels on protein metabolism in adult growth hormone deficient patients.

Nielsen S, Jørgensen JO, Hartmund T, Nørrelund H, Nair KS, Christiansen JS, Møller N.

Growth Horm IGF Res. 2002 Dec;12(6):425-33.

PMID:
12423628
39.

The effect of long-term pharmacological antilipolysis on substrate metabolism in growth hormone (GH)-substituted GH-deficient adults.

Nielsen S, Møller N, Pedersen SB, Christiansen JS, Jørgensen JO.

J Clin Endocrinol Metab. 2002 Jul;87(7):3274-8.

PMID:
12107236
40.

Effects of GH replacement in young patients with childhood onset GH deficiency.

Christiansen JS, Vahl N, Nørrelund H, Jørgensen JO.

Int J Clin Pract Suppl. 2002 May;(126):32-6. No abstract available.

PMID:
12090699
41.

Plasma ghrelin levels during exercise in healthy subjects and in growth hormone-deficient patients.

Dall R, Kanaley J, Hansen TK, Møller N, Christiansen JS, Hosoda H, Kangawa K, Jørgensen JO.

Eur J Endocrinol. 2002 Jul;147(1):65-70.

PMID:
12088921
42.
43.

Age dimorphism in the association between growth-hormone status and the respiratory quotient.

Christiansen JJ, Vahl N, Fisker S, Møller N, Christiansen JS, Jørgensen JO.

Obes Res. 2002 Apr;10(4):284-90.

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