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Items: 39

1.

Inhibiting BRAF Oncogene-Mediated Radioresistance Effectively Radiosensitizes BRAFV600E Mutant Thyroid Cancer Cells by Constraining DNA Double-strand Break Repair.

Robb R, Yang L, Shen C, Wolfe A, Webb A, Zhang X, Vedaie M, Saji M, Jhiang SM, Ringel MD, Williams TM.

Clin Cancer Res. 2019 May 16. pii: clincanres.3625.2018. doi: 10.1158/1078-0432.CCR-18-3625. [Epub ahead of print]

PMID:
31097454
2.

KRAS G12V Mutation in Acquired Resistance to Combined BRAF and MEK Inhibition in Papillary Thyroid Cancer.

Owen DH, Konda B, Sipos J, Liu T, Webb A, Ringel MD, Timmers CD, Shah MH.

J Natl Compr Canc Netw. 2019 May 1;17(5):409-413. doi: 10.6004/jnccn.2019.7292.

PMID:
31085763
3.

Using NHSN's Antimicrobial Use Option to Monitor and Improve Antibiotic Stewardship in Neonates.

O'Leary EN, van Santen KL, Edwards EM, Braun D, Buus-Frank ME, Edwards JR, Guzman-Cottrill JA, Horbar JD, Lee GM, Neuhauser MM, Roberts J, Schulman J, Septimus E, Soll RF, Srinivasan A, Webb AK, Pollock DA.

Hosp Pediatr. 2019 May;9(5):340-347. doi: 10.1542/hpeds.2018-0265.

PMID:
31036758
4.

MicroRNA molecular profiling identifies potential signaling pathways conferring resistance to chemoradiation in locally-advanced rectal adenocarcinoma.

Pettit C, Webb A, Walston S, Chatterjee M, Chen W, Frankel W, Croce C, Williams TM.

Oncotarget. 2018 Jun 22;9(48):28951-28964. doi: 10.18632/oncotarget.25652. eCollection 2018 Jun 22.

5.

Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies.

Sá ACC, Webb A, Gong Y, McDonough CW, Shahin MH, Datta S, Langaee TY, Turner ST, Beitelshees AL, Chapman AB, Boerwinkle E, Gums JG, Scherer SE, Cooper-DeHoff RM, Sadee W, Johnson JA.

BMC Med Genomics. 2018 Jun 20;11(1):55. doi: 10.1186/s12920-018-0370-x.

6.

Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses).

McDonough CW, Magvanjav O, Sá ACC, El Rouby NM, Dave C, Deitchman AN, Kawaguchi-Suzuki M, Mei W, Shen Y, Singh RSP, Solayman M, Bailey KR, Boerwinkle E, Chapman AB, Gums JG, Webb A, Scherer SE, Sadee W, Turner ST, Cooper-DeHoff RM, Gong Y, Johnson JA.

Circ Genom Precis Med. 2018 Apr;11(4):e001854. doi: 10.1161/CIRCGEN.117.001854.

7.

The Standardized Antimicrobial Administration Ratio: A New Metric for Measuring and Comparing Antibiotic Use.

van Santen KL, Edwards JR, Webb AK, Pollack LA, O'Leary E, Neuhauser MM, Srinivasan A, Pollock DA.

Clin Infect Dis. 2018 Jul 2;67(2):179-185. doi: 10.1093/cid/ciy075.

PMID:
29409000
8.

Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics.

Sá ACC, Webb A, Gong Y, McDonough CW, Datta S, Langaee TY, Turner ST, Beitelshees AL, Chapman AB, Boerwinkle E, Gums JG, Scherer SE, Cooper-DeHoff RM, Sadee W, Johnson JA.

Sci Rep. 2017 Nov 22;7(1):16068. doi: 10.1038/s41598-017-16343-z.

9.

Uptake of Antibiotic Stewardship Programs in US Acute Care Hospitals: Findings From the 2015 National Healthcare Safety Network Annual Hospital Survey.

O'Leary EN, van Santen KL, Webb AK, Pollock DA, Edwards JR, Srinivasan A.

Clin Infect Dis. 2017 Oct 30;65(10):1748-1750. doi: 10.1093/cid/cix651.

PMID:
29020178
10.

Replication and validation of genetic polymorphisms associated with survival after allogeneic blood or marrow transplant.

Karaesmen E, Rizvi AA, Preus LM, McCarthy PL, Pasquini MC, Onel K, Zhu X, Spellman S, Haiman CA, Stram DO, Pooler L, Sheng X, Zhu Q, Yan L, Liu Q, Hu Q, Webb A, Brock G, Clay-Gilmour AI, Battaglia S, Tritchler D, Liu S, Hahn T, Sucheston-Campbell LE.

Blood. 2017 Sep 28;130(13):1585-1596. doi: 10.1182/blood-2017-05-784637. Epub 2017 Aug 15.

11.

Molecular profiling of locally-advanced rectal adenocarcinoma using microRNA expression (Review).

Pettit C, Walston S, Wald P, Webb A, Williams TM.

Int J Oncol. 2017 Aug;51(2):393-404. doi: 10.3892/ijo.2017.4045. Epub 2017 Jun 14. Review.

PMID:
28627602
12.

Expression and splicing of ABC and SLC transporters in the human blood-brain barrier measured with RNAseq.

Suhy AM, Webb A, Papp AC, Geier EG, Sadee W.

Eur J Pharm Sci. 2017 May 30;103:47-51. doi: 10.1016/j.ejps.2017.02.010. Epub 2017 Feb 7.

PMID:
28188910
13.

Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response.

Shahin MH, Sá AC, Webb A, Gong Y, Langaee T, McDonough CW, Riva A, Beitleshees AL, Chapman AB, Gums JG, Turner ST, Boerwinkle E, Scherer SE, Sadee W, Cooper-DeHoff RM, Johnson JA.

Circ Cardiovasc Genet. 2017 Jan;10(1). pii: e001404. doi: 10.1161/CIRCGENETICS.116.001404.

14.

Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011-2014.

Weiner LM, Webb AK, Limbago B, Dudeck MA, Patel J, Kallen AJ, Edwards JR, Sievert DM.

Infect Control Hosp Epidemiol. 2016 Nov;37(11):1288-1301. Epub 2016 Aug 30.

PMID:
27573805
15.

Policies for Controlling Multidrug-Resistant Organisms in US Healthcare Facilities Reporting to the National Healthcare Safety Network, 2014.

Weiner LM, Webb AK, Walters MS, Dudeck MA, Kallen AJ.

Infect Control Hosp Epidemiol. 2016 Sep;37(9):1105-8. doi: 10.1017/ice.2016.139. Epub 2016 Jun 28.

PMID:
27350394
16.

Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus: A Randomized Trial.

Cusi K, Orsak B, Bril F, Lomonaco R, Hecht J, Ortiz-Lopez C, Tio F, Hardies J, Darland C, Musi N, Webb A, Portillo-Sanchez P.

Ann Intern Med. 2016 Sep 6;165(5):305-15. doi: 10.7326/M15-1774. Epub 2016 Jun 21.

PMID:
27322798
17.

RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles.

Webb A, Papp AC, Curtis A, Newman LC, Pietrzak M, Seweryn M, Handelman SK, Rempala GA, Wang D, Graziosa E, Tyndale RF, Lerman C, Kelsoe JR, Mash DC, Sadee W.

BMC Genomics. 2015 Nov 23;16:990. doi: 10.1186/s12864-015-2207-8.

18.

Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms.

Mascarenhas R, Pietrzak M, Smith RM, Webb A, Wang D, Papp AC, Pinsonneault JK, Seweryn M, Rempala G, Sadee W.

PLoS One. 2015 Sep 2;10(9):e0136798. doi: 10.1371/journal.pone.0136798. eCollection 2015.

19.

Analyzing allele specific RNA expression using mixture models.

Lu R, Smith RM, Seweryn M, Wang D, Hartmann K, Webb A, Sadee W, Rempala GA.

BMC Genomics. 2015 Aug 1;16:566. doi: 10.1186/s12864-015-1749-0.

20.

High Prevalence of Nonalcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus and Normal Plasma Aminotransferase Levels.

Portillo-Sanchez P, Bril F, Maximos M, Lomonaco R, Biernacki D, Orsak B, Subbarayan S, Webb A, Hecht J, Cusi K.

J Clin Endocrinol Metab. 2015 Jun;100(6):2231-8. doi: 10.1210/jc.2015-1966. Epub 2015 Apr 17.

21.

High Prevalence of Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus and Normal Plasma Aminotransferase Levels.

Portillo Sanchez P, Bril F, Maximos M, Lomonaco R, Biernacki D, Orsak B, Subbarayan S, Webb A, Hecht J, Cusi K.

J Clin Endocrinol Metab. 2014 Oct 10;100(5). doi: 10.1210/jc.2014-2739. Epub 2014 Oct 10. Retraction in: J Clin Endocrinol Metab. 2015 May;100(5):2138.

PMID:
25303488
22.

Relationship between disease severity, hyperinsulinemia, and impaired insulin clearance in patients with nonalcoholic steatohepatitis.

Bril F, Lomonaco R, Orsak B, Ortiz-Lopez C, Webb A, Tio F, Hecht J, Cusi K.

Hepatology. 2014 Jun;59(6):2178-87. doi: 10.1002/hep.26988. Epub 2014 Apr 25.

PMID:
24777953
23.

Mouse model implicates GNB3 duplication in a childhood obesity syndrome.

Goldlust IS, Hermetz KE, Catalano LM, Barfield RT, Cozad R, Wynn G, Ozdemir AC, Conneely KN, Mulle JG, Dharamrup S, Hegde MR, Kim KH, Angle B, Colley A, Webb AE, Thorland EC, Ellison JW, Rosenfeld JA, Ballif BC, Shaffer LG, Demmer LA; Unique Rare Chromosome Disorder Support Group, Rudd MK.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):14990-4. doi: 10.1073/pnas.1305999110. Epub 2013 Aug 26.

24.

Limited value of plasma cytokeratin-18 as a biomarker for NASH and fibrosis in patients with non-alcoholic fatty liver disease.

Cusi K, Chang Z, Harrison S, Lomonaco R, Bril F, Orsak B, Ortiz-Lopez C, Hecht J, Feldstein AE, Webb A, Louden C, Goros M, Tio F.

J Hepatol. 2014 Jan;60(1):167-74. doi: 10.1016/j.jhep.2013.07.042. Epub 2013 Aug 20.

PMID:
23973932
25.

Whole transcriptome RNA-Seq allelic expression in human brain.

Smith RM, Webb A, Papp AC, Newman LC, Handelman SK, Suhy A, Mascarenhas R, Oberdick J, Sadee W.

BMC Genomics. 2013 Aug 22;14:571. doi: 10.1186/1471-2164-14-571.

26.

Expression of mRNA transcripts encoding membrane transporters detected with whole transcriptome sequencing of human brain and liver.

Webb A, Papp AC, Sanford JC, Huang K, Parvin JD, Sadee W.

Pharmacogenet Genomics. 2013 May;23(5):269-78. doi: 10.1097/FPC.0b013e32835ff536.

27.

Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex.

Smith RM, Papp AC, Webb A, Ruble CL, Munsie LM, Nisenbaum LK, Kleinman JE, Lipska BK, Sadee W.

Biol Psychiatry. 2013 Mar 15;73(6):546-54. doi: 10.1016/j.biopsych.2012.09.028. Epub 2012 Nov 13.

28.

Assessment of FANCD2 nuclear foci formation in paraffin-embedded tumors: a potential patient-enrichment strategy for treatment with DNA interstrand crosslinking agents.

Duan W, Gao L, Zhao W, Leon M, Sadee W, Webb A, Resnick K, Wu X, Ramaswamy B, Cohn DE, Shapiro C, Andreassen PR, Otterson GA, Villalona-Calero MA.

Transl Res. 2013 Mar;161(3):156-64. doi: 10.1016/j.trsl.2012.09.003. Epub 2012 Oct 11.

29.

Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease.

Lomonaco R, Ortiz-Lopez C, Orsak B, Webb A, Hardies J, Darland C, Finch J, Gastaldelli A, Harrison S, Tio F, Cusi K.

Hepatology. 2012 May;55(5):1389-97. doi: 10.1002/hep.25539. Epub 2012 Mar 18.

PMID:
22183689
30.

Role of ethnicity in overweight and obese patients with nonalcoholic steatohepatitis.

Lomonaco R, Ortiz-Lopez C, Orsak B, Finch J, Webb A, Bril F, Louden C, Tio F, Cusi K.

Hepatology. 2011 Sep 2;54(3):837-45. doi: 10.1002/hep.24483. Epub 2011 Aug 8.

PMID:
21674556
31.

The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis.

Webb A, Lind PA, Kalmijn J, Feiler HS, Smith TL, Schuckit MA, Wilhelmsen K.

Alcohol Clin Exp Res. 2011 Jan;35(1):10-8. doi: 10.1111/j.1530-0277.2010.01317.x. Epub 2010 Oct 19.

32.

Cognitive efficiency is associated with endogenous cytokine levels in patients with chronic hepatitis C.

Hilsabeck RC, Anstead GM, Webb AL, Hoyumpa A, Ingmundson P, Holliday S, Zhang Q, Casas AM, Jovel M, Stern SL.

J Neuroimmunol. 2010 Apr 15;221(1-2):53-61. doi: 10.1016/j.jneuroim.2010.01.017. Epub 2010 Feb 24.

PMID:
20181398
33.

Role of the tau gene region chromosome inversion in progressive supranuclear palsy, corticobasal degeneration, and related disorders.

Webb A, Miller B, Bonasera S, Boxer A, Karydas A, Wilhelmsen KC.

Arch Neurol. 2008 Nov;65(11):1473-8. doi: 10.1001/archneur.65.11.1473.

34.

Food Stamp Program participation but not food insecurity is associated with higher adult BMI in Massachusetts residents living in low-income neighbourhoods.

Webb AL, Schiff A, Currivan D, Villamor E.

Public Health Nutr. 2008 Dec;11(12):1248-55. doi: 10.1017/S1368980008002309. Epub 2008 May 8.

PMID:
18462559
35.

A simple index to measure hygiene behaviours.

Webb AL, Stein AD, Ramakrishnan U, Hertzberg VS, Urizar M, Martorell R.

Int J Epidemiol. 2006 Dec;35(6):1469-77. Epub 2006 Oct 5.

PMID:
17023500
36.

Sarcoidosis after treatment with interferon-alpha: a case series and review of the literature.

Goldberg HJ, Fiedler D, Webb A, Jagirdar J, Hoyumpa AM, Peters J.

Respir Med. 2006 Nov;100(11):2063-8. Epub 2006 May 3. Review.

37.

Alcohol biomarker screening in medical and surgical settings.

Miller PM, Spies C, Neumann T, Javors MA, Hoyumpa AM, Roache J, Webb A, Kashi M, Sharkey FE, Anton RF, Egan BM, Basile J, Nguyen S, Fleming MF, Dillie KS.

Alcohol Clin Exp Res. 2006 Feb;30(2):185-93.

PMID:
16441267
38.

Dietary lignans: potential role in cancer prevention.

Webb AL, McCullough ML.

Nutr Cancer. 2005;51(2):117-31. Review.

PMID:
15860433
39.

Verbal dyspraxia and galactosemia.

Webb AL, Singh RH, Kennedy MJ, Elsas LJ.

Pediatr Res. 2003 Mar;53(3):396-402.

PMID:
12595586

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