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The CTLA-4 rs231775 GG genotype is associated with favorable 90-day survival in Caucasian patients with sepsis.

Mewes C, Büttner B, Hinz J, Alpert A, Popov AF, Ghadimi M, Beissbarth T, Tzvetkov M, Shen-Orr S, Bergmann I, Mansur A.

Sci Rep. 2018 Oct 11;8(1):15140. doi: 10.1038/s41598-018-33246-9.


Adjuvant Therapy Using Mistletoe Containing Drugs Boosts the T-Cell-Mediated Killing of Glioma Cells and Prolongs the Survival of Glioma Bearing Mice.

Schötterl S, Huber SM, Lentzen H, Mittelbronn M, Naumann U.

Evid Based Complement Alternat Med. 2018 Aug 27;2018:3928572. doi: 10.1155/2018/3928572. eCollection 2018.


Characteristics and associated risk factors of diverticular disease assessed by magnetic resonance imaging in subjects from a Western general population.

Storz C, Rothenbacher T, Rospleszcz S, Linseisen J, Messmann H, De Cecco CN, Machann J, Lorbeer R, Kiefer LS, Wintermeyer E, Rado SD, Nikolaou K, Elser S, Rathmann W, Reiser MF, Peters A, Schlett CL, Bamberg F.

Eur Radiol. 2018 Aug 27. doi: 10.1007/s00330-018-5687-5. [Epub ahead of print]


Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP.

Subramanian H, Froese A, Jönsson P, Schmidt H, Gorelik J, Nikolaev VO.

Nat Commun. 2018 Jun 22;9(1):2446. doi: 10.1038/s41467-018-04891-5.


Human Oncoviruses and p53 Tumor Suppressor Pathway Deregulation at the Origin of Human Cancers.

Tornesello ML, Annunziata C, Tornesello AL, Buonaguro L, Buonaguro FM.

Cancers (Basel). 2018 Jun 22;10(7). pii: E213. doi: 10.3390/cancers10070213. Review.


Association between abdominal adiposity and subclinical measures of left-ventricular remodeling in diabetics, prediabetics and normal controls without history of cardiovascular disease as measured by magnetic resonance imaging: results from the KORA-FF4 Study.

Schlett CL, Lorbeer R, Arndt C, Auweter S, Machann J, Hetterich H, Linkohr B, Rathmann W, Peters A, Bamberg F.

Cardiovasc Diabetol. 2018 Jun 12;17(1):88. doi: 10.1186/s12933-018-0721-0.


Emerging role of immunotherapy for childhood cancers.

Handgretinger R, Schlegel P.

Chin Clin Oncol. 2018 Apr;7(2):14. doi: 10.21037/cco.2018.04.06. Review.


Valley Manipulation by Optically Tuning the Magnetic Proximity Effect in WSe2/CrI3 Heterostructures.

Seyler KL, Zhong D, Huang B, Linpeng X, Wilson NP, Taniguchi T, Watanabe K, Yao W, Xiao D, McGuire MA, Fu KC, Xu X.

Nano Lett. 2018 Jun 13;18(6):3823-3828. doi: 10.1021/acs.nanolett.8b01105. Epub 2018 May 21.


NF-κB Activation in Lymphoid Malignancies: Genetics, Signaling, and Targeted Therapy.

Grondona P, Bucher P, Schulze-Osthoff K, Hailfinger S, Schmitt A.

Biomedicines. 2018 Mar 26;6(2). pii: E38. doi: 10.3390/biomedicines6020038. Review.


Simultaneous multislice diffusion-weighted imaging in whole-body positron emission tomography/magnetic resonance imaging for multiparametric examination in oncological patients.

Taron J, Schraml C, Pfannenberg C, Reimold M, Schwenzer N, Nikolaou K, Martirosian P, Seith F.

Eur Radiol. 2018 Aug;28(8):3372-3383. doi: 10.1007/s00330-017-5216-y. Epub 2018 Feb 26.


Immune monitoring and TCR sequencing of CD4 T cells in a long term responsive patient with metastasized pancreatic ductal carcinoma treated with individualized, neoepitope-derived multipeptide vaccines: a case report.

Sonntag K, Hashimoto H, Eyrich M, Menzel M, Schubach M, Döcker D, Battke F, Courage C, Lambertz H, Handgretinger R, Biskup S, Schilbach K.

J Transl Med. 2018 Feb 6;16(1):23. doi: 10.1186/s12967-018-1382-1.


MR arthrography of the hip: diagnostic performance and image quality of 3D-steady state free precession versus 2D turbo spin echo sequences.

Kraus MS, Notohamiprodjo M, Partovi S, Sobieh A, Baur-Melnyk A, Hausdorf J, Grosse U.

Skeletal Radiol. 2018 Jun;47(6):811-819. doi: 10.1007/s00256-017-2865-5. Epub 2018 Jan 12.


Diagnostic Accuracy of Simulated Low-Dose Perfusion CT to Detect Cerebral Perfusion Impairment after Aneurysmal Subarachnoid Hemorrhage: A Retrospective Analysis.

Afat S, Brockmann C, Nikoubashman O, Müller M, Thierfelder KM, Brockmann MA, Nikolaou K, Wiesmann M, Kim JH, Othman AE.

Radiology. 2018 May;287(2):643-650. doi: 10.1148/radiol.2017162707. Epub 2018 Jan 8.


Contribution of In Vivo and Organotypic 3D Models to Understanding the Role of Macrophages and Neutrophils in the Pathogenesis of Psoriasis.

Lorthois I, Asselineau D, Seyler N, Pouliot R.

Mediators Inflamm. 2017;2017:7215072. doi: 10.1155/2017/7215072. Epub 2017 Nov 8. Review.


Auditory closed-loop stimulation of EEG slow oscillations strengthens sleep and signs of its immune-supportive function.

Besedovsky L, Ngo HV, Dimitrov S, Gassenmaier C, Lehmann R, Born J.

Nat Commun. 2017 Dec 7;8(1):1984. doi: 10.1038/s41467-017-02170-3.


CD28neg. T lymphocytes of a melanoma patient harbor tumor immunity and a high frequency of germline-encoded and public TCRs.

Hashimoto H, Sterk M, Schilbach K.

Immunol Res. 2018 Feb;66(1):79-86. doi: 10.1007/s12026-017-8976-1.


Subtype-specific differentiation of cardiac pacemaker cell clusters from human induced pluripotent stem cells.

Schweizer PA, Darche FF, Ullrich ND, Geschwill P, Greber B, Rivinius R, Seyler C, Müller-Decker K, Draguhn A, Utikal J, Koenen M, Katus HA, Thomas D.

Stem Cell Res Ther. 2017 Oct 16;8(1):229. doi: 10.1186/s13287-017-0681-4.


Van der Waals engineering of ferromagnetic semiconductor heterostructures for spin and valleytronics.

Zhong D, Seyler KL, Linpeng X, Cheng R, Sivadas N, Huang B, Schmidgall E, Taniguchi T, Watanabe K, McGuire MA, Yao W, Xiao D, Fu KC, Xu X.

Sci Adv. 2017 May 31;3(5):e1603113. doi: 10.1126/sciadv.1603113. eCollection 2017 May.


Communication skills of medical students during the OSCE: Gender-specific differences in a longitudinal trend study.

Graf J, Smolka R, Simoes E, Zipfel S, Junne F, Holderried F, Wosnik A, Doherty AM, Menzel K, Herrmann-Werner A.

BMC Med Educ. 2017 May 2;17(1):75. doi: 10.1186/s12909-017-0913-4.


Long-term safety and efficacy of combined tiotropium and olodaterol in Japanese patients with chronic obstructive pulmonary disease.

Ichinose M, Kato M, Takizawa A, Sakamoto W, Grönke L, Tetzlaff K, Fukuchi Y.

Respir Investig. 2017 Mar;55(2):121-129. doi: 10.1016/j.resinv.2016.09.004. Epub 2016 Dec 22.


Magnetic resonance imaging of the inferior alveolar nerve with special regard to metal artifact reduction.

Probst M, Richter V, Weitz J, Kirschke JS, Ganter C, Troeltzsch M, Nittka M, Cornelius CP, Zimmer C, Probst FA.

J Craniomaxillofac Surg. 2017 Apr;45(4):558-569. doi: 10.1016/j.jcms.2017.01.009. Epub 2017 Jan 25.


STUB1/CHIP mutations cause Gordon Holmes syndrome as part of a widespread multisystemic neurodegeneration: evidence from four novel mutations.

Hayer SN, Deconinck T, Bender B, Smets K, Züchner S, Reich S, Schöls L, Schüle R, De Jonghe P, Baets J, Synofzik M.

Orphanet J Rare Dis. 2017 Feb 13;12(1):31. doi: 10.1186/s13023-017-0580-x.


Evaluation of multimodal segmentation based on 3D T1-, T2- and FLAIR-weighted images - the difficulty of choosing.

Lindig T, Kotikalapudi R, Schweikardt D, Martin P, Bender F, Klose U, Ernemann U, Focke NK, Bender B.

Neuroimage. 2018 Apr 15;170:210-221. doi: 10.1016/j.neuroimage.2017.02.016. Epub 2017 Feb 7.


Late onset Krabbe disease due to the new GALC p.Ala543Pro mutation, with intriguingly high residual GALC activity in vitro.

Krägeloh-Mann I, Harzer K, Rostásy K, Beck-Wödl S, Bornemann A, Böhringer J, Bevot A, Beck V, Merkel G, Pechan M.

Eur J Paediatr Neurol. 2017 May;21(3):522-529. doi: 10.1016/j.ejpn.2016.12.012. Epub 2017 Jan 6.


c-FLIP Expression in Foxp3-Expressing Cells Is Essential for Survival of Regulatory T Cells and Prevention of Autoimmunity.

Plaza-Sirvent C, Schuster M, Neumann Y, Heise U, Pils MC, Schulze-Osthoff K, Schmitz I.

Cell Rep. 2017 Jan 3;18(1):12-22. doi: 10.1016/j.celrep.2016.12.022.


Cardiovascular magnetic resonance patterns of biopsy proven cardiac involvement in systemic sclerosis.

Krumm P, Mueller KA, Klingel K, Kramer U, Horger MS, Zitzelsberger T, Kandolf R, Gawaz M, Nikolaou K, Klumpp BD, Henes JC.

J Cardiovasc Magn Reson. 2016 Oct 21;18(1):70.


A simple approach to a new T8-POSS based MRI contrast agent.

Strauch H, Engelmann J, Scheffler K, Mayer HA.

Dalton Trans. 2016 Sep 27;45(38):15104-15113.


Macrophage migration inhibitory factor (MIF) is induced by cytotoxic drugs and is involved in immune escape and migration in childhood rhabdomyosarcoma.

Johler SM, Fuchs J, Seitz G, Armeanu-Ebinger S.

Cancer Immunol Immunother. 2016 Dec;65(12):1465-1476. Epub 2016 Sep 15.


MR-guided microwave ablation in hepatic tumours: initial results in clinical routine.

Hoffmann R, Rempp H, Keßler DE, Weiß J, Pereira PL, Nikolaou K, Clasen S.

Eur Radiol. 2017 Apr;27(4):1467-1476. doi: 10.1007/s00330-016-4517-x. Epub 2016 Aug 23.


Diffusion-weighted echo planar MR imaging of the neck at 3 T using integrated shimming: comparison of MR sequence techniques for reducing artifacts caused by magnetic-field inhomogeneities.

Gatidis S, Graf H, Weiß J, Stemmer A, Kiefer B, Nikolaou K, Notohamiprodjo M, Martirosian P.

MAGMA. 2017 Feb;30(1):57-63. doi: 10.1007/s10334-016-0582-z. Epub 2016 Aug 8.


The second report of a new hypomyelinating disease due to a defect in the VPS11 gene discloses a massive lysosomal involvement.

Hörtnagel K, Krägeloh-Mann I, Bornemann A, Döcker M, Biskup S, Mayrhofer H, Battke F, du Bois G, Harzer K.

J Inherit Metab Dis. 2016 Nov;39(6):849-857. Epub 2016 Jul 29.


Personalized peptide vaccine-induced immune response associated with long-term survival of a metastatic cholangiocarcinoma patient.

Löffler MW, Chandran PA, Laske K, Schroeder C, Bonzheim I, Walzer M, Hilke FJ, Trautwein N, Kowalewski DJ, Schuster H, Günder M, Carcamo Yañez VA, Mohr C, Sturm M, Nguyen HP, Riess O, Bauer P, Nahnsen S, Nadalin S, Zieker D, Glatzle J, Thiel K, Schneiderhan-Marra N, Clasen S, Bösmüller H, Fend F, Kohlbacher O, Gouttefangeas C, Stevanović S, Königsrainer A, Rammensee HG.

J Hepatol. 2016 Oct;65(4):849-855. doi: 10.1016/j.jhep.2016.06.027. Epub 2016 Jul 7. Erratum in: J Hepatol. 2017 Jan;66(1):252-253.


CYP2U1 mutations in two Iranian patients with activity induced dystonia, motor regression and spastic paraplegia.

Kariminejad A, Schöls L, Schüle R, Tonekaboni SH, Abolhassani A, Fadaee M, Rosti RO, Gleeson JG.

Eur J Paediatr Neurol. 2016 Sep;20(5):782-7. doi: 10.1016/j.ejpn.2016.05.013. Epub 2016 Jun 2.


Feasibility of self-gated isotropic radial late-phase MR imaging of the liver.

Weiss J, Taron J, Othman AE, Grimm R, Kuendel M, Martirosian P, Ruff C, Schraml C, Nikolaou K, Notohamiprodjo M.

Eur Radiol. 2017 Mar;27(3):985-994. doi: 10.1007/s00330-016-4433-0. Epub 2016 Jun 8.


Optimized depiction of thalamic substructures with a combination of T1-MPRAGE and phase: MPRAGE.

Bender B, Wagner S, Klose U.

Clin Neuroradiol. 2017 Dec;27(4):511-518. doi: 10.1007/s00062-016-0513-4. Epub 2016 Apr 27.


Testicular seminoma clinical stage 1: treatment outcome on a routine care level.

Dieckmann KP, Dralle-Filiz I, Matthies C, Heinzelbecker J, Bedke J, Ellinger J, Anheuser P, Souchon R, Pichlmeier U; German Testicular Cancer Study Group.

J Cancer Res Clin Oncol. 2016 Jul;142(7):1599-607. doi: 10.1007/s00432-016-2162-z. Epub 2016 Apr 26.


11th German Conference on Chemoinformatics (GCC 2015) : Fulda, Germany. 8-10 November 2015.

Fechner U, de Graaf C, Torda AE, Güssregen S, Evers A, Matter H, Hessler G, Richmond NJ, Schmidtke P, Segler MHS, Waller MP, Pleik S, Shea JE, Levine Z, Mullen R, van den Broek K, Epple M, Kuhn H, Truszkowski A, Zielesny A, Fraaije JH, Gracia RS, Kast SM, Bulusu KC, Bender A, Yosipof A, Nahum O, Senderowitz H, Krotzky T, Schulz R, Wolber G, Bietz S, Rarey M, Zimmermann MO, Lange A, Ruff M, Heidrich J, Onlia I, Exner TE, Boeckler FM, Bermudez M, Firaha DS, Hollóczki O, Kirchner B, Tautermann CS, Volkamer A, Eid S, Turk S, Rippmann F, Fulle S, Saleh N, Saladino G, Gervasio FL, Haensele E, Banting L, Whitley DC, Oliveira Santos JS, Bureau R, Clark T, Sandmann A, Lanig H, Kibies P, Heil J, Hoffgaard F, Frach R, Engel J, Smith S, Basu D, Rauh D, Kohlbacher O, Boeckler FM, Essex JW, Bodnarchuk MS, Ross GA, Finkelmann AR, Göller AH, Schneider G, Husch T, Schütter C, Balducci A, Korth M, Ntie-Kang F, Günther S, Sippl W, Mbaze LM, Ntie-Kang F, Simoben CV, Lifongo LL, Ntie-Kang F, Judson P, Barilla J, Lokajíček MV, Pisaková H, Simr P, Kireeva N, Petrov A, Ostroumov D, Solovev VP, Pervov VS, Friedrich NO, Sommer K, Rarey M, Kirchmair J, Proschak E, Weber J, Moser D, Kalinowski L, Achenbach J, Mackey M, Cheeseright T, Renner G, Renner G, Schmidt TC, Schram J, Egelkraut-Holtus M, van Oeyen A, Kalliokoski T, Fourches D, Ibezim A, Mbah CJ, Adikwu UM, Nwodo NJ, Steudle A, Masek BB, Nagy S, Baker D, Soltanshahi F, Dorfman R, Dubrucq K, Patel H, Koch O, Mrugalla F, Kast SM, Ain QU, Fuchs JE, Owen RM, Omoto K, Torella R, Pryde DC, Glen R, Bender A, Hošek P, Spiwok V, Mervin LH, Barrett I, Firth M, Murray DC, McWilliams L, Cao Q, Engkvist O, Warszycki D, Śmieja M, Bojarski AJ, Aniceto N, Freitas A, Ghafourian T, Herrmann G, Eigner-Pitto V, Naß A, Kurczab R, Bojarski AJ, Lange A, Günther MB, Hennig S, Büttner FM, Schall C, Sievers-Engler A, Ansideri F, Koch P, Stehle T, Laufer S, Böckler FM, Zdrazil B, Montanari F, Ecker GF, Grebner C, Hogner A, Ulander J, Edman K, Guallar V, Tyrchan C, Ulander J, Tyrchan C, Klute W, Bergström F, Kramer C, Nguyen QD, Frach R, Kibies P, Strohfeldt S, Böttcher S, Pongratz T, Horinek D, Kast SM, Rupp B, Al-Yamori R, Lisurek M, Kühne R, Furtado F, van den Broek K, Wessjohann L, Mathea M, Baumann K, Mohamad-Zobir SZ, Fu X, Fan TP, Bender A, Kuhn MA, Sotriffer CA, Zoufir A, Li X, Mervin L, Berg E, Polokoff M, Ihlenfeldt WD, Ihlenfeldt WD, Pretzel J, Alhalabi Z, Fraczkiewicz R, Waldman M, Clark RD, Shaikh N, Garg P, Kos A, Himmler HJ, Sandmann A, Jardin C, Sticht H, Steinbrecher TB, Dahlgren M, Cappel D, Lin T, Wang L, Krilov G, Abel R, Friesner R, Sherman W, Pöhner IA, Panecka J, Wade RC, Bietz S, Schomburg KT, Hilbig M, Rarey M, Jäger C, Wieczorek V, Westerhoff LM, Borbulevych OY, Demuth HU, Buchholz M, Schmidt D, Rickmeyer T, Krotzky T, Kolb P, Mittal S, Sánchez-García E, Nogueira MS, Oliveira TB, da Costa FB, Schmidt TJ.

J Cheminform. 2016 Apr 26;8(Suppl 1):18. doi: 10.1186/s13321-016-0119-5. No abstract available.


Labeling Human Melanoma Cells With SPIO: In Vitro Observations.

Spira D, Bantleon R, Wolburg H, Schick F, Groezinger G, Wiskirchen J, Wiesinger B.

Mol Imaging. 2016 Jan 29;15. pii: 1536012115624915. doi: 10.1177/1536012115624915. Print 2016.


The immunomodulation potential of the synthetic derivatives of benzothiazoles: Implications in immune system disorders through in vitro and in silico studies.

Khan KM, Mesaik MA, Abdalla OM, Rahim F, Soomro S, Halim SA, Mustafa G, Ambreen N, Khalid AS, Taha M, Perveen S, Alam MT, Hameed A, Ul-Haq Z, Ullah H, Rehman ZU, Siddiqui RA, Voelter W.

Bioorg Chem. 2016 Feb;64:21-8. doi: 10.1016/j.bioorg.2015.11.004. Epub 2015 Nov 19.


Structural basis of head to head polyketide fusion by CorB.

Zocher G, Vilstrup J, Heine D, Hallab A, Goralski E, Hertweck C, Stahl M, Schäberle TF, Stehle T.

Chem Sci. 2015 Nov 1;6(11):6525-6536. doi: 10.1039/c5sc02488a. Epub 2015 Aug 6.


Abnormal Paraplegin Expression in Swollen Neurites, τ- and α-Synuclein Pathology in a Case of Hereditary Spastic Paraplegia SPG7 with an Ala510Val Mutation.

Thal DR, Züchner S, Gierer S, Schulte C, Schöls L, Schüle R, Synofzik M.

Int J Mol Sci. 2015 Oct 21;16(10):25050-66. doi: 10.3390/ijms161025050.


Poor graft function can be durably and safely improved by CD34+-selected stem cell boosts after allogeneic unrelated matched or mismatched hematopoietic cell transplantation.

Haen SP, Schumm M, Faul C, Kanz L, Bethge WA, Vogel W.

J Cancer Res Clin Oncol. 2015 Dec;141(12):2241-51. doi: 10.1007/s00432-015-2027-x. Epub 2015 Aug 14.


Preemptive administration of human αβ T cell receptor-targeting monoclonal antibody GZ-αβTCR potently abrogates aggressive graft-versus-host disease in vivo.

Blank G, Welker C, Sipos B, Sonntag K, Müller F, Eckert F, Seitz C, Nadalin S, LaCorcia G, Königsrainer A, Snell D, Handgretinger R, Schilbach K.

Ann Hematol. 2015 Nov;94(11):1907-19. doi: 10.1007/s00277-015-2471-3. Epub 2015 Aug 13.


Quantitative Assessment of Iron-Labeled Stem-Cell Adhesion at the Vessel Wall in a Vascular Flow Model: Correlation of T2*-Weighted Imaging at 3 T and Histology.

Grözinger G, Schick F, Eibofner F, Wiesinger B, Schenk M, Grosse U, Wendel HP, Elser S, Nikolaou K, Schmehl J.

J Vasc Interv Radiol. 2015 Nov;26(11):1728-34.e1-3. doi: 10.1016/j.jvir.2015.06.018. Epub 2015 Jul 29.


Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy.

Carlier M, Taccone FS, Beumier M, Seyler L, Cotton F, Jacobs F, Roberts JA.

Int J Antimicrob Agents. 2015 Oct;46(4):413-9. doi: 10.1016/j.ijantimicag.2015.05.020. Epub 2015 Jul 6.


PROSAIKA: a prospective multicenter registry with the first programmable gravitational device for hydrocephalus shunting.

Kehler U, Kiefer M, Eymann R, Wagner W, Tschan CA, Langer N, Rohde V, Ludwig HC, Gliemroth J, Meier U, Lemcke J, Thomale UW, Fritsch M, Krauss JK, Mirzayan MJ, Schuhmann M, Huthmann A.

Clin Neurol Neurosurg. 2015 Oct;137:132-6. doi: 10.1016/j.clineuro.2015.07.002. Epub 2015 Jul 8.


Chronic graft-versus-host-disease in CD34(+)-humanized NSG mice is associated with human susceptibility HLA haplotypes for autoimmune disease.

Sonntag K, Eckert F, Welker C, Müller H, Müller F, Zips D, Sipos B, Klein R, Blank G, Feuchtinger T, Schumm M, Handgretinger R, Schilbach K.

J Autoimmun. 2015 Aug;62:55-66. doi: 10.1016/j.jaut.2015.06.006. Epub 2015 Jul 3.


Inflammation and Cancer: What Can We Therapeutically Expect from Checkpoint Inhibitors?

Mischinger J, Comperat E, Schwentner C, Stenzl A, Gakis G.

Curr Urol Rep. 2015 Sep;16(9):59. doi: 10.1007/s11934-015-0532-8. Review.


Evaluation of the 'Prostate Interdisciplinary Communication and Mapping Algorithm for Biopsy and Pathology' (PIC-MABP).

Junker D, Herrmann TR, Bader M, Bektic J, Henkel G, Kruck S, Sandbichler M, Schilling D, Schäfer G, Nagele U; Training Research in Urological Surgery Therapy (T.R.U.S.T.) group.

World J Urol. 2016 Feb;34(2):245-52. doi: 10.1007/s00345-015-1627-z. Epub 2015 Jul 1.


Treatment of Primary Hypophysitis in Germany.

Honegger J, Buchfelder M, Schlaffer S, Droste M, Werner S, Strasburger C, Störmann S, Schopohl J, Kacheva S, Deutschbein T, Stalla G, Flitsch J, Milian M, Petersenn S, Elbelt U; Pituitary Working Group of the German Society of Endocrinology.

J Clin Endocrinol Metab. 2015 Sep;100(9):3460-9. doi: 10.1210/jc.2015-2146. Epub 2015 Jun 19.


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