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Items: 8


U.S. Regulatory Considerations for Development of Live Biotherapeutic Products as Drugs.

Dreher-Lesnick SM, Stibitz S, Carlson PE Jr.

Microbiol Spectr. 2017 Oct;5(5). doi: 10.1128/microbiolspec.BAD-0017-2017.


Development of Phage Lysin LysA2 for Use in Improved Purity Assays for Live Biotherapeutic Products.

Dreher-Lesnick SM, Schreier JE, Stibitz S.

Viruses. 2015 Dec 16;7(12):6675-88. doi: 10.3390/v7122965.


An anomalous type IV secretion system in Rickettsia is evolutionarily conserved.

Gillespie JJ, Ammerman NC, Dreher-Lesnick SM, Rahman MS, Worley MJ, Setubal JC, Sobral BS, Azad AF.

PLoS One. 2009;4(3):e4833. doi: 10.1371/journal.pone.0004833. Epub 2009 Mar 12.


Functional characterization and novel rickettsiostatic effects of a Kunitz-type serine protease inhibitor from the tick Dermacentor variabilis.

Ceraul SM, Dreher-Lesnick SM, Mulenga A, Rahman MS, Azad AF.

Infect Immun. 2008 Nov;76(11):5429-35. doi: 10.1128/IAI.00866-08. Epub 2008 Sep 8.


Genome-wide screen for temperature-regulated genes of the obligate intracellular bacterium, Rickettsia typhi.

Dreher-Lesnick SM, Ceraul SM, Rahman MS, Azad AF.

BMC Microbiol. 2008 Apr 15;8:61. doi: 10.1186/1471-2180-8-61.


New tick defensin isoform and antimicrobial gene expression in response to Rickettsia montanensis challenge.

Ceraul SM, Dreher-Lesnick SM, Gillespie JJ, Rahman MS, Azad AF.

Infect Immun. 2007 Apr;75(4):1973-83. Epub 2007 Jan 29.


The lspA gene, encoding the type II signal peptidase of Rickettsia typhi: transcriptional and functional analysis.

Rahman MS, Ceraul SM, Dreher-Lesnick SM, Beier MS, Azad AF.

J Bacteriol. 2007 Jan;189(2):336-41. Epub 2006 Nov 10.


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