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Items: 43


Analysis of the immune response in infants hospitalized with viral bronchiolitis shows different Th1/Th2 profiles associated with respiratory syncytial virus and human rhinovirus.

Fedele G, Schiavoni I, Nenna R, Pierangeli A, Frassanito A, Leone P, Petrarca L, Scagnolari C, Midulla F.

Pediatr Allergy Immunol. 2018 Aug;29(5):555-557. doi: 10.1111/pai.12919. Epub 2018 May 30. No abstract available.


Diagnostic performance of commercial serological assays measuring Bordetella pertussis IgG antibodies.

Fedele G, Leone P, Bellino S, Schiavoni I, Pavia C, Lazzarotto T, Stefanelli P.

Diagn Microbiol Infect Dis. 2018 Mar;90(3):157-162. doi: 10.1016/j.diagmicrobio.2017.11.006. Epub 2017 Nov 13.


CD38 modulates respiratory syncytial virus-driven proinflammatory processes in human monocyte-derived dendritic cells.

Schiavoni I, Scagnolari C, Horenstein AL, Leone P, Pierangeli A, Malavasi F, Ausiello CM, Fedele G.

Immunology. 2018 May;154(1):122-131. doi: 10.1111/imm.12873. Epub 2017 Dec 18.


Protection against Pertussis in Humans Correlates to Elevated Serum Antibodies and Memory B Cells.

Marcellini V, Piano Mortari E, Fedele G, Gesualdo F, Pandolfi E, Midulla F, Leone P, Stefanelli P, Tozzi AE, Carsetti R; Pertussis Study Group.

Front Immunol. 2017 Sep 15;8:1158. doi: 10.3389/fimmu.2017.01158. eCollection 2017.


Nitric oxide interacts with monoamine oxidase to modulate aggression and anxiety-like behaviour.

Carreño Gutiérrez H, O'Leary A, Freudenberg F, Fedele G, Wilkinson R, Markham E, van Eeden F, Reif A, Norton WHJ.

Eur Neuropsychopharmacol. 2017 Sep 23. pii: S0924-977X(17)30906-9. doi: 10.1016/j.euroneuro.2017.09.004. [Epub ahead of print]


Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity.

Fedele G, Schiavoni I, Adkins I, Klimova N, Sebo P.

Toxins (Basel). 2017 Sep 21;9(10). pii: E293. doi: 10.3390/toxins9100293. Review.


Pertussis in infants and the resurgence of a vaccine preventable disease: what to do? Commentary.

Fedele G, Stefanelli P.

Ann Ist Super Sanita. 2017 Apr-Jun;53(2):100-103. doi: 10.4415/ANN_17_02_04.


Geographical analysis of diapause inducibility in European Drosophila melanogaster populations.

Pegoraro M, Zonato V, Tyler ER, Fedele G, Kyriacou CP, Tauber E.

J Insect Physiol. 2017 Apr;98:238-244. doi: 10.1016/j.jinsphys.2017.01.015. Epub 2017 Jan 25.


Severe pertussis infection in infants less than 6 months of age: Clinical manifestations and molecular characterization.

Stefanelli P, Buttinelli G, Vacca P, Tozzi AE, Midulla F, Carsetti R, Fedele G, Villani A, Concato C; Pertussis Study Group.

Hum Vaccin Immunother. 2017 May 4;13(5):1073-1077. doi: 10.1080/21645515.2016.1276139. Epub 2017 Jan 27.


Does Breastfeeding Protect Young Infants From Pertussis? Case-control Study and Immunologic Evaluation.

Pandolfi E, Gesualdo F, Carloni E, Villani A, Midulla F, Carsetti R, Stefanelli P, Fedele G, Tozzi AE; Pertussis Study Group.

Pediatr Infect Dis J. 2017 Mar;36(3):e48-e53. doi: 10.1097/INF.0000000000001418.


Parents as source of pertussis transmission in hospitalized young infants.

Fedele G, Carollo M, Palazzo R, Stefanelli P, Pandolfi E, Gesualdo F, Tozzi AE, Carsetti R, Villani A, Nicolai A, Midulla F, Ausiello CM; Pertussis Study Group.

Infection. 2017 Apr;45(2):171-178. doi: 10.1007/s15010-016-0943-6. Epub 2016 Sep 10.


An Intronic Polymorphism in couch potato Is Not Distributed Clinally in European Drosophila melanogaster Populations nor Does It Affect Diapause Inducibility.

Zonato V, Fedele G, Kyriacou CP.

PLoS One. 2016 Sep 6;11(9):e0162370. doi: 10.1371/journal.pone.0162370. eCollection 2016.


Evidence of increased circulation of Bordetella pertussis in the Italian adult population from seroprevalence data (2012-2013).

Palazzo R, Carollo M, Fedele G, Rizzo C, Rota MC, Giammanco A, Iannazzo S, Ausiello CM, Sero-Epidemiology Working Group.

J Med Microbiol. 2016 Jul;65(7):649-657. doi: 10.1099/jmm.0.000264. Epub 2016 Apr 13.


Persistence of T-cell immune response induced by two acellular pertussis vaccines in children five years after primary vaccination.

Palazzo R, Carollo M, Bianco M, Fedele G, Schiavoni I, Pandolfi E, Villani A, Tozzi AE, Mascart F, Ausiello CM.

New Microbiol. 2016 Jan;39(1):35-47.


T-cell immune responses to Bordetella pertussis infection and vaccination.

Fedele G, Cassone A, Ausiello CM.

Pathog Dis. 2015 Oct;73(7). pii: ftv051. doi: 10.1093/femspd/ftv051. Epub 2015 Aug 4. Review.


Unconventional, adenosine-producing suppressor T cells induced by dendritic cells exposed to BPZE1 pertussis vaccine.

Fedele G, Sanseverino I, D'Agostino K, Schiavoni I, Locht C, Horenstein AL, Malavasi F, Ausiello CM.

J Leukoc Biol. 2015 Oct;98(4):631-9. doi: 10.1189/jlb.3A0315-101R. Epub 2015 Jun 18.


Genetic analysis of circadian responses to low frequency electromagnetic fields in Drosophila melanogaster.

Fedele G, Edwards MD, Bhutani S, Hares JM, Murbach M, Green EW, Dissel S, Hastings MH, Rosato E, Kyriacou CP.

PLoS Genet. 2014 Dec 4;10(12):e1004804. doi: 10.1371/journal.pgen.1004804. eCollection 2014 Dec.


An electromagnetic field disrupts negative geotaxis in Drosophila via a CRY-dependent pathway.

Fedele G, Green EW, Rosato E, Kyriacou CP.

Nat Commun. 2014 Jul 14;5:4391. doi: 10.1038/ncomms5391.


Live attenuated B. pertussis BPZE1 rescues the immune functions of Respiratory Syncytial virus infected human dendritic cells by promoting Th1/Th17 responses.

Schiavoni I, Fedele G, Quattrini A, Bianco M, Schnoeller C, Openshaw PJ, Locht C, Ausiello CM.

PLoS One. 2014 Jun 26;9(6):e100166. doi: 10.1371/journal.pone.0100166. eCollection 2014.


A Drosophila RNAi collection is subject to dominant phenotypic effects.

Green EW, Fedele G, Giorgini F, Kyriacou CP.

Nat Methods. 2014 Mar;11(3):222-3. doi: 10.1038/nmeth.2856. No abstract available.


CD38 ligation in peripheral blood mononuclear cells of myeloma patients induces release of protumorigenic IL-6 and impaired secretion of IFNγ cytokines and proliferation.

Fedele G, Di Girolamo M, Recine U, Palazzo R, Urbani F, Horenstein AL, Malavasi F, Ausiello CM.

Mediators Inflamm. 2013;2013:564687. doi: 10.1155/2013/564687. Epub 2013 Dec 30.


The virulence factors of Bordetella pertussis: talented modulators of host immune response.

Fedele G, Bianco M, Ausiello CM.

Arch Immunol Ther Exp (Warsz). 2013 Dec;61(6):445-57. doi: 10.1007/s00005-013-0242-1. Epub 2013 Aug 18. Review.


The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia.

Brusa D, Serra S, Coscia M, Rossi D, D'Arena G, Laurenti L, Jaksic O, Fedele G, Inghirami G, Gaidano G, Malavasi F, Deaglio S.

Haematologica. 2013 Jun;98(6):953-63. doi: 10.3324/haematol.2012.077537. Epub 2013 Jan 8.


Hepatitis B specific T cell immunity induced by primary vaccination persists independently of the protective serum antibody level.

Carollo M, Palazzo R, Bianco M, Pandolfi E, Chionne P, Fedele G, Tozzi AE, Carsetti R, Romanò L, Ausiello CM.

Vaccine. 2013 Jan 7;31(3):506-13. doi: 10.1016/j.vaccine.2012.11.029. Epub 2012 Nov 19.


Chlamydia pneumoniae modulates human monocyte-derived dendritic cells functions driving the induction of a Type 1/Type 17 inflammatory response.

Flego D, Bianco M, Quattrini A, Mancini F, Carollo M, Schiavoni I, Ciervo A, Ausiello CM, Fedele G.

Microbes Infect. 2013 Feb;15(2):105-14. doi: 10.1016/j.micinf.2012.11.004. Epub 2012 Nov 16.


Identity and ranking of colonic mesenchymal stromal cells.

Signore M, Cerio AM, Boe A, Pagliuca A, Zaottini V, Schiavoni I, Fedele G, Petti S, Navarra S, Ausiello CM, Pelosi E, Fatica A, Sorrentino A, Valtieri M.

J Cell Physiol. 2012 Sep;227(9):3291-300. doi: 10.1002/jcp.24027.


Attenuated Bordetella pertussis vaccine candidate BPZE1 promotes human dendritic cell CCL21-induced migration and drives a Th1/Th17 response.

Fedele G, Bianco M, Debrie AS, Locht C, Ausiello CM.

J Immunol. 2011 May 1;186(9):5388-96. doi: 10.4049/jimmunol.1003765. Epub 2011 Mar 23.


Immunomodulatory activities of surface-layer proteins obtained from epidemic and hypervirulent Clostridium difficile strains.

Bianco M, Fedele G, Quattrini A, Spigaglia P, Barbanti F, Mastrantonio P, Ausiello CM.

J Med Microbiol. 2011 Aug;60(Pt 8):1162-7. doi: 10.1099/jmm.0.029694-0. Epub 2011 Feb 24.


Bordetella pertussis commits human dendritic cells to promote a Th1/Th17 response through the activity of adenylate cyclase toxin and MAPK-pathways.

Fedele G, Spensieri F, Palazzo R, Nasso M, Cheung GY, Coote JG, Ausiello CM.

PLoS One. 2010 Jan 15;5(1):e8734. doi: 10.1371/journal.pone.0008734.


Genetically detoxified pertussis toxin induces Th1/Th17 immune response through MAPKs and IL-10-dependent mechanisms.

Nasso M, Fedele G, Spensieri F, Palazzo R, Costantino P, Rappuoli R, Ausiello CM.

J Immunol. 2009 Aug 1;183(3):1892-9. doi: 10.4049/jimmunol.0901071. Epub 2009 Jul 13.


A natural pertactin deficient strain of Bordetella pertussis shows improved entry in human monocyte-derived dendritic cells.

Stefanelli P, Fazio C, Fedele G, Spensieri F, Ausiello CM, Mastrantonio P.

New Microbiol. 2009 Apr;32(2):159-66.


IFN-gamma arms human dendritic cells to perform multiple effector functions.

Frasca L, Nasso M, Spensieri F, Fedele G, Palazzo R, Malavasi F, Ausiello CM.

J Immunol. 2008 Feb 1;180(3):1471-81.


Use of whole-blood samples in in-house bulk and single-cell antigen-specific gamma interferon assays for surveillance of Mycobacterium tuberculosis infections.

Palazzo R, Spensieri F, Massari M, Fedele G, Frasca L, Carrara S, Goletti D, Ausiello CM.

Clin Vaccine Immunol. 2008 Feb;15(2):327-37. Epub 2007 Nov 21.


Lipooligosaccharide from Bordetella pertussis induces mature human monocyte-derived dendritic cells and drives a Th2 biased response.

Fedele G, Celestino I, Spensieri F, Frasca L, Nasso M, Watanabe M, Remoli ME, Coccia EM, Altieri F, Ausiello CM.

Microbes Infect. 2007 Jun;9(7):855-63. Epub 2007 Mar 12.


CD38 and CD157 as receptors of the immune system: a bridge between innate and adaptive immunity.

Malavasi F, Deaglio S, Ferrero E, Funaro A, Sancho J, Ausiello CM, Ortolan E, Vaisitti T, Zubiaur M, Fedele G, Aydin S, Tibaldi EV, Durelli I, Lusso R, Cozno F, Horenstein AL.

Mol Med. 2006 Nov-Dec;12(11-12):334-41. Review.


Surface layer proteins from Clostridium difficile induce inflammatory and regulatory cytokines in human monocytes and dendritic cells.

Ausiello CM, Cerquetti M, Fedele G, Spensieri F, Palazzo R, Nasso M, Frezza S, Mastrantonio P.

Microbes Infect. 2006 Sep;8(11):2640-6. Epub 2006 Aug 8.


60-kDa heat shock protein of Chlamydia pneumoniae promotes a T helper type 1 immune response through IL-12/IL-23 production in monocyte-derived dendritic cells.

Ausiello CM, Fedele G, Palazzo R, Spensieri F, Ciervo A, Cassone A.

Microbes Infect. 2006 Mar;8(3):714-20. Epub 2006 Jan 11.


CD38 orchestrates migration, survival, and Th1 immune response of human mature dendritic cells.

Frasca L, Fedele G, Deaglio S, Capuano C, Palazzo R, Vaisitti T, Malavasi F, Ausiello CM.

Blood. 2006 Mar 15;107(6):2392-9. Epub 2005 Nov 17.


Bordetella pertussis-infected human monocyte-derived dendritic cells undergo maturation and induce Th1 polarization and interleukin-23 expression.

Fedele G, Stefanelli P, Spensieri F, Fazio C, Mastrantonio P, Ausiello CM.

Infect Immun. 2005 Mar;73(3):1590-7.


CD38 is expressed on human mature monocyte-derived dendritic cells and is functionally involved in CD83 expression and IL-12 induction.

Fedele G, Frasca L, Palazzo R, Ferrero E, Malavasi F, Ausiello CM.

Eur J Immunol. 2004 May;34(5):1342-50.


Native and genetically inactivated pertussis toxins induce human dendritic cell maturation and synergize with lipopolysaccharide in promoting T helper type 1 responses.

Ausiello CM, Fedele G, Urbani F, Lande R, Di Carlo B, Cassone A.

J Infect Dis. 2002 Aug 1;186(3):351-60. Epub 2002 Jul 17.


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