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1.

Patients' Attitudes Towards Deprescribing Alpha-Blockers and Their Willingness to Participate in a Discontinuation Trial.

Edelman M, Jellema P, Hak E, Denig P, Blanker MH.

Drugs Aging. 2019 Sep 13. doi: 10.1007/s40266-019-00712-6. [Epub ahead of print]

PMID:
31515710
2.

Chronic Use of Proton-Pump Inhibitors and Iron Status in Renal Transplant Recipients.

Douwes RM, Gomes-Neto AW, Eisenga MF, Vinke JSJ, de Borst MH, van den Berg E, Berger SP, Touw DJ, Hak E, Blokzijl H, Navis G, Bakker SJL.

J Clin Med. 2019 Sep 3;8(9). pii: E1382. doi: 10.3390/jcm8091382.

3.

Treatment outcomes of drug-resistant tuberculosis in the Netherlands, 2005-2015.

Pradipta IS, Van't Boveneind-Vrubleuskaya N, Akkerman OW, Alffenaar JC, Hak E.

Antimicrob Resist Infect Control. 2019 Jul 12;8:115. doi: 10.1186/s13756-019-0561-z. eCollection 2019.

4.

Pneumococcal conjugate vaccines for preventing acute otitis media in children.

Fortanier AC, Venekamp RP, Boonacker CW, Hak E, Schilder AG, Sanders EA, Damoiseaux RA.

Cochrane Database Syst Rev. 2019 May 28;5:CD001480. doi: 10.1002/14651858.CD001480.pub5.

PMID:
31135969
5.

The KupA and KupB Proteins of Lactococcus lactis IL1403 Are Novel c-di-AMP Receptor Proteins Responsible for Potassium Uptake.

Quintana IM, Gibhardt J, Turdiev A, Hammer E, Commichau FM, Lee VT, Magni C, Stülke J.

J Bacteriol. 2019 Apr 24;201(10). pii: e00028-19. doi: 10.1128/JB.00028-19. Print 2019 May 15.

PMID:
30745376
6.

Nanoparticle Ligand-Decoration Procedures Affect in Vivo Interactions with Immune Cells.

Sofias AM, Andreassen T, Hak S.

Mol Pharm. 2018 Dec 3;15(12):5754-5761. doi: 10.1021/acs.molpharmaceut.8b00908. Epub 2018 Nov 8.

PMID:
30376341
7.

Clinical outcomes of endoscopic resection for colorectal laterally spreading tumors with advanced histology.

Jung JS, Hong JY, Oh HH, Kweon SS, Lee J, Kim SW, Seo GS, Kim HS, Joo YE.

Surg Endosc. 2019 Aug;33(8):2562-2571. doi: 10.1007/s00464-018-6550-0. Epub 2018 Oct 22.

PMID:
30350100
8.

Continuous Near-Infrared Spectroscopy Demonstrates Limitations in Monitoring the Development of Acute Compartment Syndrome in Patients with Leg Injuries.

Schmidt AH, Bosse MJ, Obremskey WT, O'Toole RV, Carroll EA, Stinner DJ, Hak DJ, Karunakar M, Hayda R, Frey KP, Di J, Zipunnikov V, MacKenzie E; Major Extremity Trauma Research Consortium (METRC).

J Bone Joint Surg Am. 2018 Oct 3;100(19):1645-1652. doi: 10.2106/JBJS.17.01495. Erratum in: J Bone Joint Surg Am. 2018 Dec 5;100(23):e151.

PMID:
30277994
9.

Long-term incidence and risk factors of cardiovascular events in Asian populations: systematic review and meta-analysis of population-based cohort studies.

Irawati S, Wasir R, Floriaan Schmidt A, Islam A, Feenstra T, Buskens E, Wilffert B, Hak E.

Curr Med Res Opin. 2019 Feb;35(2):291-299. doi: 10.1080/03007995.2018.1491149. Epub 2018 Jul 30.

PMID:
29920124
10.

Factors associated with health-related quality of life, hip function, and health utility after operative management of femoral neck fractures.

Sprague S, Bhandari M, Heetveld MJ, Liew S, Scott T, Bzovsky S, Heels-Ansdell D, Zhou Q, Swiontkowski M, Schemitsch EH; FAITH Investigators.

Bone Joint J. 2018 Mar 1;100-B(3):361-369. doi: 10.1302/0301-620X.100B3.BJJ-2017-0853.R1.

PMID:
29589490
11.

Association between hunting and elevated blood lead levels in the critically endangered African white-backed vulture Gyps africanus.

Garbett R, Maude G, Hancock P, Kenny D, Reading R, Amar A.

Sci Total Environ. 2018 Jul 15;630:1654-1665. doi: 10.1016/j.scitotenv.2018.02.220. Epub 2018 Mar 15.

PMID:
29550066
12.

Sugarcane juice derived carbon dot-graphitic carbon nitride composites for bisphenol A degradation under sunlight irradiation.

Sim LC, Wong JL, Hak CH, Tai JY, Leong KH, Saravanan P.

Beilstein J Nanotechnol. 2018 Jan 30;9:353-363. doi: 10.3762/bjnano.9.35. eCollection 2018.

13.

Key parameters influencing metallic element mobility associated with sediments in a daily-managed reservoir.

Frémion F, Mourier B, Courtin-Nomade A, Lenain JF, Annouri A, Fondanèche P, Hak T, Bordas F.

Sci Total Environ. 2017 Dec 15;605-606:666-676. doi: 10.1016/j.scitotenv.2017.06.236. Epub 2017 Jul 1.

PMID:
28675876
14.

Nitric oxide signalling and neuronal nitric oxide synthase in the heart under stress.

Zhang YH.

F1000Res. 2017 May 23;6:742. doi: 10.12688/f1000research.10128.1. eCollection 2017. Review.

15.

Influenza vaccine effectiveness estimates in the Dutch population from 2003 to 2014: The test-negative design case-control study with different control groups.

van Doorn E, Darvishian M, Dijkstra F, Donker GA, Overduin P, Meijer A, Hak E.

Vaccine. 2017 May 15;35(21):2831-2839. doi: 10.1016/j.vaccine.2017.04.012. Epub 2017 Apr 12.

16.

Evaluation of the immunogenicity and safety of different doses and formulations of a broad spectrum influenza vaccine (FLU-v) developed by SEEK: study protocol for a single-center, randomized, double-blind and placebo-controlled clinical phase IIb trial.

van Doorn E, Pleguezuelos O, Liu H, Fernandez A, Bannister R, Stoloff G, Oftung F, Norley S, Huckriede A, Frijlink HW, Hak E.

BMC Infect Dis. 2017 Apr 4;17(1):241. doi: 10.1186/s12879-017-2341-9.

17.

Orthopaedic trauma surgeons and direct anterior total hip arthroplasty: evaluation of learning curve at a level I academic institution.

York PJ, Logterman SL, Hak DJ, Mavrogenis A, Mauffrey C.

Eur J Orthop Surg Traumatol. 2017 Apr;27(3):421-424. doi: 10.1007/s00590-017-1937-5. Epub 2017 Mar 3.

PMID:
28258304
18.

Impact of Intensity-Modulated Radiation Therapy Technique for Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the NRG Oncology RTOG 0617 Randomized Clinical Trial.

Chun SG, Hu C, Choy H, Komaki RU, Timmerman RD, Schild SE, Bogart JA, Dobelbower MC, Bosch W, Galvin JM, Kavadi VS, Narayan S, Iyengar P, Robinson CG, Wynn RB, Raben A, Augspurger ME, MacRae RM, Paulus R, Bradley JD.

J Clin Oncol. 2017 Jan;35(1):56-62. Epub 2016 Oct 31.

19.

Influenza Vaccine Research funded by the European Commission FP7-Health-2013-Innovation-1 project.

Liu H, Frijlink HW, Huckriede A, van Doorn E, Schmidt E, Leroy O, Rimmelzwaan G, McCullough K, Whelan M, Hak E.

Vaccine. 2016 Nov 21;34(48):5845-5854. doi: 10.1016/j.vaccine.2016.10.040. Epub 2016 Oct 25. Review.

PMID:
27793486
20.

Prevalence of oral cancer, oral potentially malignant disorders and other oral mucosal lesions in Cambodia.

Chher T, Hak S, Kallarakkal TG, Durward C, Ramanathan A, Ghani WMN, Razak IA, Harun MH, Ashar NAM, Rajandram RK, Prak P, Hussaini HM, Zain RB.

Ethn Health. 2018 Jan;23(1):1-15. doi: 10.1080/13557858.2016.1246431. Epub 2016 Oct 26.

PMID:
27781495
21.

Sarcopenia as a Predictor of Future Cognitive Impairment in Older Adults.

Moon JH, Moon JH, Kim KM, Choi SH, Lim S, Park KS, Kim KW, Jang HC.

J Nutr Health Aging. 2016;20(5):496-502. doi: 10.1007/s12603-015-0613-x.

PMID:
27102786
22.

Reprint of: Pendant allyl crosslinking as a tunable shape memory actuator for vascular applications.

Boire TC, Gupta MK, Zachman AL, Lee SH, Balikov DA, Kim K, Bellan LM, Sung HJ.

Acta Biomater. 2016 Apr 1;34:73-83. doi: 10.1016/j.actbio.2016.03.021.

PMID:
27018333
23.

Roles and Transport of Sodium and Potassium in Plants.

Nieves-Cordones M, Al Shiblawi FR, Sentenac H.

Met Ions Life Sci. 2016;16:291-324. doi: 10.1007/978-3-319-21756-7_9.

PMID:
26860305
24.

Safety and tolerability evaluation of the use of Montanide ISA™51 as vaccine adjuvant: A systematic review.

van Doorn E, Liu H, Huckriede A, Hak E.

Hum Vaccin Immunother. 2016;12(1):159-69. doi: 10.1080/21645515.2015.1071455. Epub 2015 Sep 17. Review.

25.

National Differences in Requirements for Ethical and Competent Authority Approval for a Multinational Vaccine Trial under the EU Directive 2001/20/EC.

van Doorn E, Hak E, Wilffert B.

Vaccines (Basel). 2015 Apr 14;3(2):263-92. doi: 10.3390/vaccines3020263. Review.

26.

Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors.

Savi L, Brindisi M, Alfano G, Butini S, La Pietra V, Novellino E, Marinelli L, Lossani A, Focher F, Cavella C, Campiani G, Gemma S.

Chem Biol Drug Des. 2016 Jan;87(1):112-20. doi: 10.1111/cbdd.12630. Epub 2015 Sep 18.

PMID:
26242695
27.

First prospective report on immune tolerance in poor risk haemophilia A inhibitor patients with a single factor VIII/von Willebrand factor concentrate in an observational immune tolerance induction study.

Kreuz W, Escuriola Ettingshausen C, Vdovin V, Zozulya N, Plyushch O, Svirin P, Andreeva T, Bubanská E, Campos M, Benedik-Dolničar M, Jiménez-Yuste V, Kitanovski L, Klukowska A, Momot A, Osmulskaya N, Prieto M, Šalek SZ, Velasco F, Pavlova A, Oldenburg J, Knaub S, Jansen M, Belyanskaya L, Walter O; ObsITI study group; ObsITI committee.

Haemophilia. 2016 Jan;22(1):87-95. doi: 10.1111/hae.12774. Epub 2015 Jul 23.

PMID:
26202305
28.

Reliability, validity, and responsiveness of the Western Ontario and McMaster Universities Osteoarthritis Index for elderly patients with a femoral neck fracture.

Burgers PT, Poolman RW, Van Bakel TM, Tuinebreijer WE, Zielinski SM, Bhandari M, Patka P, Van Lieshout EM; HEALTH and FAITH Trial Investigators.

J Bone Joint Surg Am. 2015 May 6;97(9):751-7. doi: 10.2106/JBJS.N.00542.

PMID:
25948522
29.

Novel observational study designs with new influenza vaccines.

Hak E.

Lancet Infect Dis. 2015 Mar;15(3):253-4. doi: 10.1016/S1473-3099(15)70020-4. Epub 2015 Feb 9. No abstract available.

PMID:
25672569
30.

Effects and cost-effectiveness of pharmacogenetic screening for CYP2D6 among older adults starting therapy with nortriptyline or venlafaxine: study protocol for a pragmatic randomized controlled trial (CYSCEtrial).

Berm EJ, Hak E, Postma M, Boshuisen M, Breuning L, Brouwers JR, Dhondt T, Jansen PA, Kok RM, Maring JG, van Marum R, Mulder H, Voshaar RC, Risselada AJ, Venema H, Vleugel L, Wilffert B.

Trials. 2015 Jan 31;16:37. doi: 10.1186/s13063-015-0561-0.

31.

A simple dried blood spot method for therapeutic drug monitoring of the tricyclic antidepressants amitriptyline, nortriptyline, imipramine, clomipramine, and their active metabolites using LC-MS/MS.

Berm EJJ, Paardekooper J, Brummel-Mulder E, Hak E, Wilffert B, Maring JG.

Talanta. 2015 Mar;134:165-172. doi: 10.1016/j.talanta.2014.10.041. Epub 2014 Oct 29.

PMID:
25618654
32.

Effectiveness of seasonal influenza vaccine in community-dwelling elderly people: a meta-analysis of test-negative design case-control studies.

Darvishian M, Bijlsma MJ, Hak E, van den Heuvel ER.

Lancet Infect Dis. 2014 Dec;14(12):1228-39. doi: 10.1016/S1473-3099(14)70960-0. Epub 2014 Nov 6.

PMID:
25455990
33.

Phase II trial of stereotactic body radiation therapy combined with erlotinib for patients with limited but progressive metastatic non-small-cell lung cancer.

Iyengar P, Kavanagh BD, Wardak Z, Smith I, Ahn C, Gerber DE, Dowell J, Hughes R, Abdulrahman R, Camidge DR, Gaspar LE, Doebele RC, Bunn PA, Choy H, Timmerman R.

J Clin Oncol. 2014 Dec 1;32(34):3824-30. doi: 10.1200/JCO.2014.56.7412. Epub 2014 Oct 27.

PMID:
25349291
34.

Stepping asymmetry among individuals with unilateral transtibial limb loss might be functional in terms of gait stability.

Hak L, van Dieën JH, van der Wurff P, Houdijk H.

Phys Ther. 2014 Oct;94(10):1480-8. doi: 10.2522/ptj.20130431. Epub 2014 Jun 5.

PMID:
24903115
35.

After adjusting for bias in meta-analysis seasonal influenza vaccine remains effective in community-dwelling elderly.

Darvishian M, Gefenaite G, Turner RM, Pechlivanoglou P, Van der Hoek W, Van den Heuvel ER, Hak E.

J Clin Epidemiol. 2014 Jul;67(7):734-44. doi: 10.1016/j.jclinepi.2014.02.009. Epub 2014 Apr 24. Review.

36.

Defining membrane spanning domains and crucial membrane-localized acidic amino acid residues for K⁺ transport of a Kup/HAK/KT-type Escherichia coli potassium transporter.

Sato Y, Nanatani K, Hamamoto S, Shimizu M, Takahashi M, Tabuchi-Kobayashi M, Mizutani A, Schroeder JI, Souma S, Uozumi N.

J Biochem. 2014 May;155(5):315-23. doi: 10.1093/jb/mvu007. Epub 2014 Feb 11.

PMID:
24519967
37.

Effect of sauchinone, a lignan from Saururus chinensis, on bacterial phagocytosis by macrophages.

Jeong KM, Choi JI, Lee SH, Lee HJ, Son JK, Seo CS, Song SW, Kwak SH, Bae HB.

Eur J Pharmacol. 2014 Apr 5;728:176-82. doi: 10.1016/j.ejphar.2014.01.039. Epub 2014 Jan 31.

PMID:
24486706
38.

RSV vaccine in development: assessing the potential cost-effectiveness in the Dutch elderly population.

Meijboom MJ, Pouwels KB, Luytjes W, Postma MJ, Hak E.

Vaccine. 2013 Dec 16;31(52):6254-60. doi: 10.1016/j.vaccine.2013.10.023. Epub 2013 Oct 19.

PMID:
24148573
39.

Randomized controlled trial of intensity-modulated radiotherapy for early breast cancer: 5-year results confirm superior overall cosmesis.

Mukesh MB, Barnett GC, Wilkinson JS, Moody AM, Wilson C, Dorling L, Chan Wah Hak C, Qian W, Twyman N, Burnet NG, Wishart GC, Coles CE.

J Clin Oncol. 2013 Dec 20;31(36):4488-95. doi: 10.1200/JCO.2013.49.7842. Epub 2013 Sep 16.

PMID:
24043742
40.

Use of acid-suppressive drugs in pregnancy and the risk of childhood asthma: bidirectional crossover study using the general practice research database.

Hak E, Mulder B, Schuiling-Veninga CC, de Vries TW, Jick SS.

Drug Saf. 2013 Nov;36(11):1097-104. doi: 10.1007/s40264-013-0093-z.

41.

Perceived discomfort levels in healthy children participating in vaccine research.

Westra AE, van Gils EJ, Aarts F, Rodenburg GD, Veenhoven RH, Hak E, Scharloo M, Sukhai RN, Wit JM, de Beaufort I, Sanders EL.

J Empir Res Hum Res Ethics. 2013 Jul;8(3):66-72. doi: 10.1525/jer.2013.8.3.66.

PMID:
23933778
42.

Association of childhood attention-deficit/hyperactivity disorder with atopic diseases and skin infections? A matched case-control study using the General Practice Research Database.

Hak E, de Vries TW, Hoekstra PJ, Jick SS.

Ann Allergy Asthma Immunol. 2013 Aug;111(2):102-106.e2. doi: 10.1016/j.anai.2013.05.023. Epub 2013 Jun 21.

PMID:
23886227
43.

Association of infant pneumococcal vaccination with pneumococcal pneumonia among mothers: a nested case-control study using the GPRD.

Hak E, Shea KM, Jick SS.

Vaccine. 2013 Mar 15;31(12):1590-6. doi: 10.1016/j.vaccine.2013.01.018. Epub 2013 Jan 25.

PMID:
23357195
44.

K(+) uptake systems in the yeast Hansenula polymorpha. Transcriptional and post-translational mechanisms involved in high-affinity K(+) transporter regulation.

Cabrera E, Álvarez MC, Martín Y, Siverio JM, Ramos J.

Fungal Genet Biol. 2012 Sep;49(9):755-63. doi: 10.1016/j.fgb.2012.06.008. Epub 2012 Jul 6.

PMID:
22776636
45.

Dermatomyositis and polymyositis: new treatment targets on the horizon.

Hak AE, de Paepe B, de Bleecker JL, Tak PP, de Visser M.

Neth J Med. 2011 Oct;69(10):410-21. Review.

46.

Effect of 7-valent pneumococcal conjugate vaccine on nasopharyngeal carriage with Haemophilus influenzae and Moraxella catarrhalis in a randomized controlled trial.

van Gils EJ, Veenhoven RH, Rodenburg GD, Hak E, Sanders EA.

Vaccine. 2011 Oct 13;29(44):7595-8. doi: 10.1016/j.vaccine.2011.08.049. Epub 2011 Sep 3.

PMID:
21893151
47.

Effect of seven-valent pneumococcal conjugate vaccine on Staphylococcus aureus colonisation in a randomised controlled trial.

van Gils EJ, Hak E, Veenhoven RH, Rodenburg GD, Bogaert D, Bruin JP, van Alphen L, Sanders EA.

PLoS One. 2011;6(6):e20229. doi: 10.1371/journal.pone.0020229. Epub 2011 Jun 10.

48.

How to develop a program to increase influenza vaccine uptake among workers in health care settings?

Looijmans-van den Akker I, Hulscher ME, Verheij TJ, Riphagen-Dalhuisen J, van Delden JJ, Hak E.

Implement Sci. 2011 May 19;6:47. doi: 10.1186/1748-5908-6-47.

49.

Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies.

Butini S, Gemma S, Brindisi M, Borrelli G, Lossani A, Ponte AM, Torti A, Maga G, Marinelli L, La Pietra V, Fiorini I, Lamponi S, Campiani G, Zisterer DM, Nathwani SM, Sartini S, La Motta C, Da Settimo F, Novellino E, Focher F.

J Med Chem. 2011 Mar 10;54(5):1401-20. doi: 10.1021/jm101438u. Epub 2011 Feb 14.

PMID:
21319802
50.

The p-type ATPase superfamily.

Chan H, Babayan V, Blyumin E, Gandhi C, Hak K, Harake D, Kumar K, Lee P, Li TT, Liu HY, Lo TC, Meyer CJ, Stanford S, Zamora KS, Saier MH Jr.

J Mol Microbiol Biotechnol. 2010;19(1-2):5-104. doi: 10.1159/000319588. Epub 2010 Oct 20. Review.

PMID:
20962537

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