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Items: 1 to 20 of 99


Impaired pressure natriuresis and non-dipping blood pressure in rats with early type 1 diabetes mellitus.

Culshaw GJ, Costello HM, Binnie D, Stewart KR, Czopek A, Dhaun N, Hadoke PWF, Webb DJ, Bailey MA.

J Physiol. 2019 Feb;597(3):767-780. doi: 10.1113/JP277332. Epub 2018 Dec 23.


WT1 expression in vessels varies with histopathological grade in tumour-bearing and control tissue from patients with breast cancer.

McGregor RJ, Chau YY, Kendall TJ, Artibani M, Hastie N, Hadoke PWF.

Br J Cancer. 2018 Dec;119(12):1508-1517. doi: 10.1038/s41416-018-0317-1. Epub 2018 Oct 30.


Dysregulation of Cortisol Metabolism in Equine Pituitary Pars Intermedia Dysfunction.

Morgan RA, Keen JA, Homer N, Nixon M, McKinnon-Garvin AM, Moses-Williams JA, Davis SR, Hadoke PWF, Walker BR.

Endocrinology. 2018 Nov 1;159(11):3791-3800. doi: 10.1210/en.2018-00726.


Leukemia Inhibitory Factor-Receptor is Dispensable for Prenatal Testis Development but is Required in Sertoli cells for Normal Spermatogenesis in Mice.

Curley M, Milne L, Smith S, Atanassova N, Rebourcet D, Darbey A, Hadoke PWF, Wells S, Smith LB.

Sci Rep. 2018 Aug 1;8(1):11532. doi: 10.1038/s41598-018-30011-w.


Robust Revascularization in Models of Limb Ischemia Using a Clinically Translatable Human Stem Cell-Derived Endothelial Cell Product.

MacAskill MG, Saif J, Condie A, Jansen MA, MacGillivray TJ, Tavares AAS, Fleisinger L, Spencer HL, Besnier M, Martin E, Biglino G, Newby DE, Hadoke PWF, Mountford JC, Emanueli C, Baker AH.

Mol Ther. 2018 Jul 5;26(7):1669-1684. doi: 10.1016/j.ymthe.2018.03.017. Epub 2018 Mar 28.


The role of androgen receptors in atherosclerosis.

Takov K, Wu J, Denvir MA, Smith LB, Hadoke PWF.

Mol Cell Endocrinol. 2018 Apr 15;465:82-91. doi: 10.1016/j.mce.2017.10.006. Epub 2017 Oct 9. Review.


Correction to"Inhaled Nanoparticles Accumulate at Sites of Vascular Disease".

Miller MR, Raftis JB, Langrish JP, McLean SG, Samutrtai P, Connell SP, Wilson S, Vesey AT, Fokkens PHB, Boere AJF, Krystek P, Campbell CJ, Hadoke PWF, Donaldson K, Cassee FR, Newby DE, Duffin R, Mills NL.

ACS Nano. 2017 Oct 24;11(10):10623-10624. doi: 10.1021/acsnano.7b06327. Epub 2017 Oct 4. No abstract available.


Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity.

Morgan RA, Beck KR, Nixon M, Homer NZM, Crawford AA, Melchers D, Houtman R, Meijer OC, Stomby A, Anderson AJ, Upreti R, Stimson RH, Olsson T, Michoel T, Cohain A, Ruusalepp A, Schadt EE, Björkegren JLM, Andrew R, Kenyon CJ, Hadoke PWF, Odermatt A, Keen JA, Walker BR.

Sci Rep. 2017 Sep 6;7(1):10633. doi: 10.1038/s41598-017-10410-1.


Macrophage 11β-HSD-1 deficiency promotes inflammatory angiogenesis.

Zhang Z, Coutinho AE, Man TY, Kipari TMJ, Hadoke PWF, Salter DM, Seckl JR, Chapman KE.

J Endocrinol. 2017 Sep;234(3):291-299. doi: 10.1530/JOE-17-0223. Epub 2017 Jul 4.


Inhaled Nanoparticles Accumulate at Sites of Vascular Disease.

Miller MR, Raftis JB, Langrish JP, McLean SG, Samutrtai P, Connell SP, Wilson S, Vesey AT, Fokkens PHB, Boere AJF, Krystek P, Campbell CJ, Hadoke PWF, Donaldson K, Cassee FR, Newby DE, Duffin R, Mills NL.

ACS Nano. 2017 May 23;11(5):4542-4552. doi: 10.1021/acsnano.6b08551. Epub 2017 Apr 26. Erratum in: ACS Nano. 2017 Oct 24;11(10):10623-10624.


PET Cell Tracking Using 18F-FLT is Not Limited by Local Reuptake of Free Radiotracer.

MacAskill MG, Tavares AS, Wu J, Lucatelli C, Mountford JC, Baker AH, Newby DE, Hadoke PW.

Sci Rep. 2017 Mar 13;7:44233. doi: 10.1038/srep44233.


Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial.

Snowdon VK, Lachlan NJ, Hoy AM, Hadoke PW, Semple SI, Patel D, Mungall W, Kendall TJ, Thomson A, Lennen RJ, Jansen MA, Moran CM, Pellicoro A, Ramachandran P, Shaw I, Aucott RL, Severin T, Saini R, Pak J, Yates D, Dongre N, Duffield JS, Webb DJ, Iredale JP, Hayes PC, Fallowfield JA.

PLoS Med. 2017 Feb 28;14(2):e1002248. doi: 10.1371/journal.pmed.1002248. eCollection 2017 Feb.


Safer topical treatment for inflammation using 5α-tetrahydrocorticosterone in mouse models.

Gastaldello A, Livingstone DE, Abernethie AJ, Tsang N, Walker BR, Hadoke PW, Andrew R.

Biochem Pharmacol. 2017 Apr 1;129:73-84. doi: 10.1016/j.bcp.2017.01.008. Epub 2017 Jan 24.


Inhibition or deletion of 11β-HSD1 does not increase angiogenesis in ischemic retinopathy.

Davidson CT, Dover AR, McVicar CM, Megaw R, Glenn JV, Hadoke PWF, Stitt AW, Walker BR.

Diabetes Metab. 2017 Oct;43(5):480-483. doi: 10.1016/j.diabet.2016.12.001. Epub 2017 Jan 11. No abstract available.


Smooth Muscle Endothelin B Receptors Regulate Blood Pressure but Not Vascular Function or Neointimal Remodeling.

Miller E, Czopek A, Duthie KM, Kirkby NS, van de Putte EE, Christen S, Kimmitt RA, Moorhouse R, Castellan RF, Kotelevtsev YV, Kuc RE, Davenport AP, Dhaun N, Webb DJ, Hadoke PW.

Hypertension. 2017 Feb;69(2):275-285. doi: 10.1161/HYPERTENSIONAHA.115.07031. Epub 2016 Dec 27.


Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor.

Drebert Z, MacAskill M, Doughty-Shenton D, De Bosscher K, Bracke M, Hadoke PWF, Beck IM.

Vascul Pharmacol. 2017 Feb;89:19-30. doi: 10.1016/j.vph.2016.10.004. Epub 2016 Oct 4.


A Protocol for Improved Measurement of Arterial Flow Rate in Preclinical Ultrasound.

Kenwright DA, Thomson AJ, Hadoke PW, Anderson T, Moran CM, Gray GA, Hoskins PR.

Ultrasound Int Open. 2015 Nov;1(2):E46-52. doi: 10.1055/s-0035-1564268. Epub 2015 Nov 3.


Vascular Dysfunction in Horses with Endocrinopathic Laminitis.

Morgan RA, Keen JA, Walker BR, Hadoke PW.

PLoS One. 2016 Sep 29;11(9):e0163815. doi: 10.1371/journal.pone.0163815. eCollection 2016.


Early-life glucocorticoids programme behaviour and metabolism in adulthood in zebrafish.

Wilson KS, Tucker CS, Al-Dujaili EA, Holmes MC, Hadoke PW, Kenyon CJ, Denvir MA.

J Endocrinol. 2016 Jul;230(1):125-42. doi: 10.1530/JOE-15-0376.


Influence of Androgen Receptor in Vascular Cells on Reperfusion following Hindlimb Ischaemia.

Wu J, Hadoke PW, Takov K, Korczak A, Denvir MA, Smith LB.

PLoS One. 2016 May 9;11(5):e0154987. doi: 10.1371/journal.pone.0154987. eCollection 2016.

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