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Items: 1 to 20 of 196


A novel role of bone morphogenetic protein 6 (BMP6) in glucose homeostasis.

Pauk M, Bordukalo-Niksic T, Brkljacic J, Paralkar VM, Brault AL, Dumic-Cule I, Borovecki F, Grgurevic L, Vukicevic S.

Acta Diabetol. 2018 Dec 11. doi: 10.1007/s00592-018-1265-1. [Epub ahead of print]


Restriction of Zika virus infection and transmission in Aedes aegypti mediated by an insect-specific flavivirus.

Romo H, Kenney JL, Blitvich BJ, Brault AC.

Emerg Microbes Infect. 2018 Nov 15;7(1):181. doi: 10.1038/s41426-018-0180-4.


Chikungunya and Zika Viruses: Global Emerging Health Threats.

Blitvich BJ, Brault AC.

Am J Trop Med Hyg. 2018 Oct;99(4):1105-1106. doi: 10.4269/ajtmh.18-0613. No abstract available.


Heartland Virus Epidemiology, Vector Association, and Disease Potential.

Brault AC, Savage HM, Duggal NK, Eisen RJ, Staples JE.

Viruses. 2018 Sep 14;10(9). pii: E498. doi: 10.3390/v10090498. Review.


Infection of epididymal epithelial cells and leukocytes drives seminal shedding of Zika virus in a mouse model.

McDonald EM, Duggal NK, Ritter JM, Brault AC.

PLoS Negl Trop Dis. 2018 Aug 2;12(8):e0006691. doi: 10.1371/journal.pntd.0006691. eCollection 2018 Aug.


Generation of a Lineage II Powassan Virus (Deer Tick Virus) cDNA Clone: Assessment of Flaviviral Genetic Determinants of Tick and Mosquito Vector Competence.

Kenney JL, Anishchenko M, Hermance M, Romo H, Chen CI, Thangamani S, Brault AC.

Vector Borne Zoonotic Dis. 2018 Jul;18(7):371-381. doi: 10.1089/vbz.2017.2224. Epub 2018 May 21.


Bunyavirus Taxonomy: Limitations and Misconceptions Associated with the Current ICTV Criteria Used for Species Demarcation.

Blitvich BJ, Beaty BJ, Blair CD, Brault AC, Dobler G, Drebot MA, Haddow AD, Kramer LD, LaBeaud AD, Monath TP, Mossel EC, Plante K, Powers AM, Tesh RB, Turell MJ, Vasilakis N, Weaver SC.

Am J Trop Med Hyg. 2018 Jul;99(1):11-16. doi: 10.4269/ajtmh.18-0038. Epub 2018 Apr 19.


Zika Virus Shedding in Semen of Symptomatic Infected Men.

Mead PS, Duggal NK, Hook SA, Delorey M, Fischer M, Olzenak McGuire D, Becksted H, Max RJ, Anishchenko M, Schwartz AM, Tzeng WP, Nelson CA, McDonald EM, Brooks JT, Brault AC, Hinckley AF.

N Engl J Med. 2018 Apr 12;378(15):1377-1385. doi: 10.1056/NEJMoa1711038.


Comparative Vector Competence of North American Culex pipiens and Culex quinquefasciatus for African and European Lineage 2 West Nile Viruses.

Romo H, Papa A, Kading R, Clark R, Delorey M, Brault AC.

Am J Trop Med Hyg. 2018 Jun;98(6):1863-1869. doi: 10.4269/ajtmh.17-0935. Epub 2018 Apr 5.


Continued Need for Comprehensive Genetic and Phenotypic Characterization of Viruses: Benefits of Complementing Sequence Analyses with Functional Determinations.

Brault AC, Blitvich BJ.

Am J Trop Med Hyg. 2018 May;98(5):1213. doi: 10.4269/ajtmh.18-0128. Epub 2018 Mar 15. No abstract available.


Sexual transmission of Zika virus enhances in utero transmission in a mouse model.

Duggal NK, McDonald EM, Ritter JM, Brault AC.

Sci Rep. 2018 Mar 14;8(1):4510. doi: 10.1038/s41598-018-22840-6.


West Nile and St. Louis encephalitis viral genetic determinants of avian host competence.

Maharaj PD, Bosco-Lauth AM, Langevin SA, Anishchenko M, Bowen RA, Reisen WK, Brault AC.

PLoS Negl Trop Dis. 2018 Feb 15;12(2):e0006302. doi: 10.1371/journal.pntd.0006302. eCollection 2018 Feb.


Modes of Transmission of Zika Virus.

Gregory CJ, Oduyebo T, Brault AC, Brooks JT, Chung KW, Hills S, Kuehnert MJ, Mead P, Meaney-Delman D, Rabe I, Staples E, Petersen LR.

J Infect Dis. 2017 Dec 16;216(suppl_10):S875-S883. doi: 10.1093/infdis/jix396.


Increases in the competitive fitness of West Nile virus isolates after introduction into California.

Worwa G, Hutton AA, Frey M, Duggal NK, Brault AC, Reisen WK.

Virology. 2018 Jan 15;514:170-181. doi: 10.1016/j.virol.2017.11.017. Epub 2017 Nov 28.


A Zika Vaccine Targeting NS1 Protein Protects Immunocompetent Adult Mice in a Lethal Challenge Model.

Brault AC, Domi A, McDonald EM, Talmi-Frank D, McCurley N, Basu R, Robinson HL, Hellerstein M, Duggal NK, Bowen RA, Guirakhoo F.

Sci Rep. 2017 Nov 7;7(1):14769. doi: 10.1038/s41598-017-15039-8.


Lack of evidence for Zika virus transmission by Culex mosquitoes.

Roundy CM, Azar SR, Brault AC, Ebel GD, Failloux AB, Fernandez-Salas I, Kitron U, Kramer LD, Lourenço-de-Oliveira R, Osorio JE, Paploski ID, Vazquez-Prokopec GM, Ribeiro GS, Ritchie SA, Tauro LB, Vasilakis N, Weaver SC.

Emerg Microbes Infect. 2017 Oct 18;6(10):e90. doi: 10.1038/emi.2017.85. No abstract available.


Pathogenesis and sexual transmission of Spondweni and Zika viruses.

McDonald EM, Duggal NK, Brault AC.

PLoS Negl Trop Dis. 2017 Oct 6;11(10):e0005990. doi: 10.1371/journal.pntd.0005990. eCollection 2017 Oct.


The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.

Hall J, Ralph EC, Shanker S, Wang H, Byrnes LJ, Horst R, Wong J, Brault A, Dumlao D, Smith JF, Dakin LA, Schmitt DC, Trujillo J, Vincent F, Griffor M, Aulabaugh AE.

Protein Sci. 2017 Dec;26(12):2367-2380. doi: 10.1002/pro.3304. Epub 2017 Oct 25.


Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.

Hall J, Brault A, Vincent F, Weng S, Wang H, Dumlao D, Aulabaugh A, Aivazian D, Castro D, Chen M, Culp J, Dower K, Gardner J, Hawrylik S, Golenbock D, Hepworth D, Horn M, Jones L, Jones P, Latz E, Li J, Lin LL, Lin W, Lin D, Lovering F, Niljanskul N, Nistler R, Pierce B, Plotnikova O, Schmitt D, Shanker S, Smith J, Snyder W, Subashi T, Trujillo J, Tyminski E, Wang G, Wong J, Lefker B, Dakin L, Leach K.

PLoS One. 2017 Sep 21;12(9):e0184843. doi: 10.1371/journal.pone.0184843. eCollection 2017.


Differential Neurovirulence of African and Asian Genotype Zika Virus Isolates in Outbred Immunocompetent Mice.

Duggal NK, Ritter JM, McDonald EM, Romo H, Guirakhoo F, Davis BS, Chang GJ, Brault AC.

Am J Trop Med Hyg. 2017 Nov;97(5):1410-1417. doi: 10.4269/ajtmh.17-0263. Epub 2017 Aug 18.

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