Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 427

1.

Pulmonary administration of a dry powder formulation of the antifibrotic drug tilorone reduces silica-induced lung fibrosis in mice.

Vartiainen V, Raula J, Bimbo LM, Viinamäki J, Backman JT, Ugur N, Kauppinen E, Sutinen E, Joensuu E, Koli K, Myllärniemi M.

Int J Pharm. 2018 Jun 10;544(1):121-128. doi: 10.1016/j.ijpharm.2018.04.019. Epub 2018 Apr 12.

PMID:
29655797
2.

Synthesis and radiofluorination of novel fluoren-9-one based derivatives for the imaging of α7 nicotinic acetylcholine receptor with PET.

Teodoro R, Scheunemann M, Wenzel B, Peters D, Deuther-Conrad W, Brust P.

Bioorg Med Chem Lett. 2018 May 15;28(9):1471-1475. doi: 10.1016/j.bmcl.2018.03.081. Epub 2018 Mar 29.

PMID:
29628323
3.

Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection.

Ekins S, Lingerfelt MA, Comer JE, Freiberg AN, Mirsalis JC, O'Loughlin K, Harutyunyan A, McFarlane C, Green CE, Madrid PB.

Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e01711-17. doi: 10.1128/AAC.01711-17. Print 2018 Feb.

4.

Synthesis of Fluorenones from Benzaldehydes and Aryl Iodides: Dual C-H Functionalizations Using a Transient Directing Group.

Chen XY, Ozturk S, Sorensen EJ.

Org Lett. 2017 Mar 3;19(5):1140-1143. doi: 10.1021/acs.orglett.7b00161. Epub 2017 Feb 22.

PMID:
28225629
5.

Alternative pre-approved and novel therapies for the treatment of anthrax.

Head BM, Rubinstein E, Meyers AF.

BMC Infect Dis. 2016 Nov 3;16(1):621. Review.

6.

Development of potential broad spectrum antimicrobials using C2-symmetric 9-fluorenone alkyl amine.

Choi SR, Larson MA, Hinrichs SH, Narayanasamy P.

Bioorg Med Chem Lett. 2016 Apr 15;26(8):1997-9. doi: 10.1016/j.bmcl.2016.02.087. Epub 2016 Mar 2.

PMID:
26965856
7.

The effect of amixin and agmatine on cytochrome C release from isolated mitochondria

Uspenska KR, Gergalova GL, Lykhmus OY, Skok MV.

Ukr Biochem J. 2016 Jan-Feb;88(1):5-10. doi: 10.15407/ubj88.01.005.

PMID:
29227073
8.

An Effective Synthesis Method for Tilorone Dihydrochloride with Obvious IFN-α Inducing Activity.

Zhang J, Yao Q, Liu Z.

Molecules. 2015 Dec 2;20(12):21458-63. doi: 10.3390/molecules201219781.

9.

Machine learning models identify molecules active against the Ebola virus in vitro.

Ekins S, Freundlich JS, Clark AM, Anantpadma M, Davey RA, Madrid P.

Version 3. F1000Res. 2015 Oct 20 [revised 2017 Jan 1];4:1091. doi: 10.12688/f1000research.7217.3. eCollection 2015.

10.

Identification of Additional Anti-Persister Activity against Borrelia burgdorferi from an FDA Drug Library.

Feng J, Weitner M, Shi W, Zhang S, Sullivan D, Zhang Y.

Antibiotics (Basel). 2015 Sep 16;4(3):397-410. doi: 10.3390/antibiotics4030397.

11.

Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression.

Wissing MD, Dadon T, Kim E, Piontek KB, Shim JS, Kaelber NS, Liu JO, Kachhap SK, Nelkin BD.

Oncol Rep. 2014 Jul;32(1):419-24. doi: 10.3892/or.2014.3174. Epub 2014 May 13.

12.
13.

Design, synthesis and antiproliferative evaluation of fluorenone analogs with DNA topoisomerase I inhibitory properties.

Lee CC, Chang DM, Huang KF, Chen CL, Chen TC, Lo Y, Guh JH, Huang HS.

Bioorg Med Chem. 2013 Nov 15;21(22):7125-33. doi: 10.1016/j.bmc.2013.09.006. Epub 2013 Sep 13.

PMID:
24094433
14.

Small molecule inhibitors of protein interaction with glycosaminoglycans (SMIGs), a novel class of bioactive agents with anti-inflammatory properties.

Harris N, Kogan FY, Il'kova G, Juhas S, Lahmy O, Gregor YI, Koppel J, Zhuk R, Gregor P.

Biochim Biophys Acta. 2014 Jan;1840(1):245-54. doi: 10.1016/j.bbagen.2013.09.023. Epub 2013 Sep 21.

PMID:
24060749
15.

Discovery of inhibitors of Bacillus anthracis primase DnaG.

Biswas T, Green KD, Garneau-Tsodikova S, Tsodikov OV.

Biochemistry. 2013 Oct 1;52(39):6905-10. doi: 10.1021/bi4011286. Epub 2013 Sep 19.

PMID:
24004110
16.

[The role of immunomodulating therapy in the treatment and prevention of exacerbations of chronic cystitis].

Strel'tsova OS, Krupin VN, Rastorguev GG.

Urologiia. 2013 May-Jun;(3):24-6, 28. Russian.

PMID:
23987044
17.

[Effects of diphenyl derivatives on electrophoretic mobility of murine T lymphocytes].

Dolga OV, Pogoriela NKh, Bohorad-Kobel's'ka OS, Zholobak NM, Zanoza SO, Liakhov SA, Mahura IS.

Fiziol Zh. 2013;59(3):31-8. Ukrainian.

PMID:
23957162
18.

Synthesis and activity evaluation of tilorone analogs as potential anticancer agents.

Zhou D, Tuo W, Hu H, Xu J, Chen H, Rao Z, Xiao Y, Hu X, Liu P.

Eur J Med Chem. 2013 Jun;64:432-41. doi: 10.1016/j.ejmech.2013.03.050. Epub 2013 Apr 16.

PMID:
23665799
19.

[Experimental and clinicolaboratory evaluation of complex therapy efficacy in arboviral infections].

Romantsov MG, Galimzianov KhM, Lokteva OM, Kovalenko AL, Stepanov AV.

Antibiot Khimioter. 2012;57(7-8):12-22. Russian.

PMID:
23350190
20.

Bone morphogenetic protein-inducer tilorone identified by high-throughput screening is antifibrotic in vivo.

Leppäranta O, Tikkanen JM, Bespalov MM, Koli K, Myllärniemi M.

Am J Respir Cell Mol Biol. 2013 Apr;48(4):448-55. doi: 10.1165/rcmb.2012-0201OC.

PMID:
23258233

Supplemental Content

Loading ...
Support Center