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Items: 1 to 20 of 49

1.

Bradykinin 1 receptor blockade subdues systemic autoimmunity, renal inflammation, and blood pressure in murine lupus nephritis.

Qin L, Du Y, Ding H, Haque A, Hicks J, Pedroza C, Mohan C.

Arthritis Res Ther. 2019 Jan 8;21(1):12. doi: 10.1186/s13075-018-1774-x.

2.

Antitumor activity of cell-penetrant kinin B1 receptor antagonists in human triple-negative breast cancer cells.

Dubuc C, Savard M, Bovenzi V, Lessard A, Côté J, Neugebauer W, Geha S, Chemtob S, Gobeil F Jr.

J Cell Physiol. 2019 Mar;234(3):2851-2865. doi: 10.1002/jcp.27103. Epub 2018 Aug 21.

PMID:
30132865
3.

Effect of the bradykinin 1 receptor antagonist SSR240612 after oral administration in Mycobacterium tuberculosis-infected mice.

Rodrigues-Junior VS, Pail PB, Villela AD, Falcão VCA, Dadda AS, Abbadi BL, Pesquero JB, Santos DS, Basso LA, Campos MM.

Tuberculosis (Edinb). 2018 Mar;109:1-7. doi: 10.1016/j.tube.2018.01.003. Epub 2018 Feb 2.

PMID:
29559112
4.

Impact of pioglitazone and bradykinin type 1 receptor antagonist on type 2 diabetes in high-fat diet-fed C57BL/6J mice.

El Akoum S, Haddad Y, Couture R.

Obes Sci Pract. 2017 Jul 6;3(3):352-362. doi: 10.1002/osp4.117. eCollection 2017 Sep.

5.

Kininase 1 As a Preclinical Therapeutic Target for Kinin B1 Receptor in Insulin Resistance.

Haddad Y, Couture R.

Front Pharmacol. 2017 Aug 2;8:509. doi: 10.3389/fphar.2017.00509. eCollection 2017.

6.

Primary Role for Kinin B1 and B2 Receptors in Glioma Proliferation.

Nicoletti NF, Sénécal J, da Silva VD, Roxo MR, Ferreira NP, de Morais RLT, Pesquero JB, Campos MM, Couture R, Morrone FB.

Mol Neurobiol. 2017 Dec;54(10):7869-7882. doi: 10.1007/s12035-016-0265-9. Epub 2016 Nov 16.

PMID:
27848207
7.

Potentiation of Paclitaxel-Induced Pain Syndrome in Mice by Angiotensin I Converting Enzyme Inhibition and Involvement of Kinins.

Brusco I, Silva CR, Trevisan G, de Campos Velho Gewehr C, Rigo FK, La Rocca Tamiozzo L, Rossato MF, Tonello R, Dalmolin GD, de Almeida Cabrini D, Gomez MV, Ferreira J, Oliveira SM.

Mol Neurobiol. 2017 Dec;54(10):7824-7837. doi: 10.1007/s12035-016-0275-7. Epub 2016 Nov 14.

PMID:
27844290
8.

New insights into the stereochemical requirements of the bradykinin B1 receptor antagonists binding.

Lupala CS, Gomez-Gutierrez P, Perez JJ.

J Mol Graph Model. 2016 Jul;68:184-196. doi: 10.1016/j.jmgm.2016.06.010. Epub 2016 Jul 1.

PMID:
27469392
9.

Beneficial effects of kinin B1 receptor antagonism on plasma fatty acid alterations and obesity in Zucker diabetic fatty rats.

Talbot S, Dias JP, El Midaoui A, Couture R.

Can J Physiol Pharmacol. 2016 Jul;94(7):752-7. doi: 10.1139/cjpp-2016-0063. Epub 2016 Mar 5.

PMID:
27172260
10.

Cellular localisation of the kinin B1R in the pancreas of streptozotocin-treated rat and the anti-diabetic effect of the antagonist SSR240612.

Tidjane N, Gaboury L, Couture R.

Biol Chem. 2016 Apr;397(4):323-36. doi: 10.1515/hsz-2015-0230.

PMID:
26841446
11.

A primary role for kinin B1 receptor in inflammation, organ damage, and lethal thrombosis in a rat model of septic shock in diabetes.

Tidjane N, Hachem A, Zaid Y, Merhi Y, Gaboury L, Girolami JP, Couture R.

Eur J Inflamm. 2015 Apr 1;13(1):40-52.

12.

Brain kinin B1 receptor is upregulated by the oxidative stress and its activation leads to stereotypic nociceptive behavior in insulin-resistant rats.

Dias JP, Gariépy Hde B, Ongali B, Couture R.

Peptides. 2015 Jul;69:118-26. doi: 10.1016/j.peptides.2015.04.022. Epub 2015 May 8.

PMID:
25959537
13.

The role of kinin B1 receptor and the effect of angiotensin I-converting enzyme inhibition on acute gout attacks in rodents.

Silva CR, Oliveira SM, Hoffmeister C, Funck V, Guerra GP, Trevisan G, Tonello R, Rossato MF, Pesquero JB, Bader M, Oliveira MS, McDougall JJ, Ferreira J.

Ann Rheum Dis. 2016 Jan;75(1):260-8. doi: 10.1136/annrheumdis-2014-205739. Epub 2014 Oct 24.

PMID:
25344431
14.

Des-Arg9-bradykinin causes kinin B1 receptor mediated endothelium-independent contractions in endotoxin-treated porcine coronary arteries.

More AS, Kim HM, Khang G, Hildebrandt T, Bernlöhr C, Doods H, Vanhoutte PM, Wu D.

Pharmacol Res. 2014 Dec;90:18-24. doi: 10.1016/j.phrs.2014.09.001. Epub 2014 Sep 22.

PMID:
25258294
15.

COX-2 mediated induction of endothelium-independent contraction to bradykinin in endotoxin-treated porcine coronary artery.

More AS, Kim HM, Zhao R, Khang G, Hildebrandt T, Bernlöhr C, Doods H, Lee D, Lee SH, Vanhoutte PM, Wu D.

J Cardiovasc Pharmacol. 2014 Sep;64(3):209-17. doi: 10.1097/FJC.0000000000000105.

PMID:
25192543
16.

Mechanisms involved in kinin-induced glioma cells proliferation: the role of ERK1/2 and PI3K/Akt pathways.

Nicoletti NF, Erig TC, Zanin RF, Pereira TC, Bogo MR, Campos MM, Morrone FB.

J Neurooncol. 2014 Nov;120(2):235-44. doi: 10.1007/s11060-014-1549-4. Epub 2014 Jul 24.

PMID:
25056222
17.

Angiotensin-(1-7) augments endothelium-dependent relaxations of porcine coronary arteries to bradykinin by inhibiting angiotensin-converting enzyme 1.

Raffai G, Khang G, Vanhoutte PM.

J Cardiovasc Pharmacol. 2014 May;63(5):453-60. doi: 10.1097/FJC.0000000000000069.

PMID:
24390175
18.

Cognitive and cerebrovascular improvements following kinin B1 receptor blockade in Alzheimer's disease mice.

Lacoste B, Tong XK, Lahjouji K, Couture R, Hamel E.

J Neuroinflammation. 2013 May 4;10:57. doi: 10.1186/1742-2094-10-57.

19.

Functional and molecular characterization of kinin B1 and B 2 receptors in human bladder cancer: implication of the PI3Kγ pathway.

Sgnaolin V, Pereira TC, Bogo MR, Zanin R, Battastini AM, Morrone FB, Campos MM.

Invest New Drugs. 2013 Aug;31(4):812-22. doi: 10.1007/s10637-012-9907-6. Epub 2012 Dec 7.

PMID:
23224295
20.

Brain kinin B₁ receptor contributes to the onset of stereotypic nocifensive behavior in rat.

De Brito Gariepy H, Talbot S, Sénécal J, Couture R.

Behav Brain Res. 2013 Mar 15;241:17-26. doi: 10.1016/j.bbr.2012.11.032. Epub 2012 Dec 3.

PMID:
23219968

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