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Items: 1 to 20 of 44


Subchronic Toxicity Studies of Cortex Dictamni Extracts in Mice and Its Potential Hepatotoxicity Mechanisms in Vitro.

Fan Q, Zhao B, Wang C, Zhang J, Wu J, Wang T, Xu A.

Molecules. 2018 Sep 28;23(10). pii: E2486. doi: 10.3390/molecules23102486.


Fraxinellone has anticancer activity in vivo by inhibiting programmed cell death-ligand 1 expression by reducing hypoxia-inducible factor-1α and STAT3.

Xing Y, Mi C, Wang Z, Zhang ZH, Li MY, Zuo HX, Wang JY, Jin X, Ma J.

Pharmacol Res. 2018 Sep;135:166-180. doi: 10.1016/j.phrs.2018.08.004. Epub 2018 Aug 10.


Nano-delivery of fraxinellone remodels tumor microenvironment and facilitates therapeutic vaccination in desmoplastic melanoma.

Hou L, Liu Q, Shen L, Liu Y, Zhang X, Chen F, Huang L.

Theranostics. 2018 Jun 13;8(14):3781-3796. doi: 10.7150/thno.24821. eCollection 2018.


Furan-Site Bromination and Transformations of Fraxinellone as Insecticidal Agents Against Mythimna separata Walker.

Dong QM, Dong S, Shen C, Cao QH, Song MY, He QR, Wang XL, Yang XJ, Tang JJ, Gao JM.

Sci Rep. 2018 May 30;8(1):8372. doi: 10.1038/s41598-018-26747-0.


Fraxinellone Attenuates Rheumatoid Inflammation in Mice.

Jung SM, Lee J, Baek SY, Lee J, Jang SG, Hong SM, Park JS, Cho ML, Park SH, Kwok SK.

Int J Mol Sci. 2018 Mar 13;19(3). pii: E829. doi: 10.3390/ijms19030829.


Semisynthesis and insecticidal activity of some novel fraxinellone-based thioethers containing 1,3,4-oxadiazole moiety.

Guo Y, Wang X, Fan J, Zhang Q, Wang Y, Zhao Y, Huang M, Ding M, Zhang Y.

R Soc Open Sci. 2017 Dec 13;4(12):171053. doi: 10.1098/rsos.171053. eCollection 2017 Dec.


The inhibitory effect in Fraxinellone on oxidative stress-induced senescence correlates with AMP-activated protein kinase-dependent autophagy restoration.

Han X, Chen H, Zhou J, Tai H, Gong H, Wang X, Huang N, Qin J, Fang T, Wang F, Xiao H.

J Cell Physiol. 2018 May;233(5):3945-3954. doi: 10.1002/jcp.26169. Epub 2017 Sep 28.


CUG-binding protein 1 regulates HSC activation and liver fibrogenesis.

Wu X, Wu X, Ma Y, Shao F, Tan Y, Tan T, Gu L, Zhou Y, Sun B, Sun Y, Wu X, Xu Q.

Nat Commun. 2016 Nov 17;7:13498. doi: 10.1038/ncomms13498.


New Insecticidal Agents from Halogenation/Acylation of the Furyl-Ring of Fraxinellone.

Guo Y, Yang R, Xu H.

Sci Rep. 2016 Oct 24;6:35321. doi: 10.1038/srep35321.


A novel UPLC-MS/MS method for simultaneous determination of 10 effective constituents in the Jixingshizhen preparation.

Cui K, Sun S, Wang P, Luo L, Yu J, Guo X.

Biomed Chromatogr. 2017 Apr;31(4). doi: 10.1002/bmc.3854. Epub 2016 Oct 20.


Semisynthesis of Esters of Fraxinellone C4/10-Oxime and Their Pesticidal Activities.

Li Q, Huang X, Li S, Ma J, Lv M, Xu H.

J Agric Food Chem. 2016 Jul 13;64(27):5472-8. doi: 10.1021/acs.jafc.6b01995. Epub 2016 Jul 5.


Developing an activity and absorption-based quality control platform for Chinese traditional medicine: Application to Zeng-Sheng-Ping(Antitumor B).

Yin T, Yang G, Ma Y, Xu B, Hu M, You M, Gao S.

J Ethnopharmacol. 2015 Aug 22;172:195-201. doi: 10.1016/j.jep.2015.06.019. Epub 2015 Jun 20.


Suppression of NF-κB signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone.

Wu XF, Ouyang ZJ, Feng LL, Chen G, Guo WJ, Shen Y, Wu XD, Sun Y, Xu Q.

Toxicol Appl Pharmacol. 2014 Nov 15;281(1):146-56. doi: 10.1016/j.taap.2014.10.002. Epub 2014 Oct 13.


[Chemical constituents from root bark of Dictamnus dasycarpus].

Bai YY, Tang WZ, Wang XJ.

Zhong Yao Cai. 2014 Feb;37(2):263-5. Chinese.


Antimicrobial, antioxidant and cytotoxic properties of essential oil from Dictamnus angustifolius.

Sun J, Wang X, Wang P, Li L, Qu W, Liang J.

J Ethnopharmacol. 2015 Jan 15;159:296-300. doi: 10.1016/j.jep.2014.06.055. Epub 2014 Jul 2.


Acylammonium salts as dienophiles in Diels-Alder/lactonization organocascades.

Abbasov ME, Hudson BM, Tantillo DJ, Romo D.

J Am Chem Soc. 2014 Mar 26;136(12):4492-5. doi: 10.1021/ja501005g. Epub 2014 Mar 12.


Semisynthesis and insecticidal activity of some fraxinellone derivatives modified in the B ring.

Guo Y, Qu H, Zhi X, Yu X, Yang C, Xu H.

J Agric Food Chem. 2013 Dec 11;61(49):11937-44. doi: 10.1021/jf404195m. Epub 2013 Nov 25.


Simultaneous determination of limonin, dictamnine, obacunone and fraxinellone in rat plasma by a validated UHPLC-MS/MS and its application to a pharmacokinetic study after oral administration of Cortex Dictamni extract.

Wang P, Sun J, Gao E, Zhao Y, Qu W, Yu Z.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Jun 1;928:44-51. doi: 10.1016/j.jchromb.2013.03.018. Epub 2013 Mar 26.


Insecticidal and feeding deterrent effects of fraxinellone from Dictamnus dasycarpus against four major pests.

Lü M, Wu W, Liu H.

Molecules. 2013 Mar 1;18(3):2754-62. doi: 10.3390/molecules18032754.

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