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Items: 10

  • Filters activated: Toxicology. Clear all to show 14 items.
1.

ATR-101, a selective ACAT1 inhibitor, decreases ACTH-stimulated cortisol concentrations in dogs with naturally occurring Cushing's syndrome.

Langlois DK, Fritz MC, Schall WD, Bari Olivier N, Smedley RC, Pearson PG, Bailie MB, Hunt SW 3rd.

BMC Endocr Disord. 2018 May 2;18(1):24. doi: 10.1186/s12902-018-0251-5.

2.

Biochemical alterations in guinea pig adrenal cortex following administration of PD 132301-2, an inhibitor of acyl-CoA:cholesterol acyltransferase.

Wolfgang GH, MacDonald JR, Vernetti LA, Pegg DG, Robertson DG.

Life Sci. 1995 Feb 17;56(13):1089-93.

PMID:
9001442
3.
4.

Toxicologic effects of a novel acyl-CoA:cholesterol acyltransferase inhibitor in cynomolgus monkeys.

Reindel JF, Dominick MA, Bocan TM, Gough AW, McGuire EJ.

Toxicol Pathol. 1994 Sep-Oct;22(5):510-8.

PMID:
7899779
5.

Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 7. Development of a series of substituted N-phenyl-N'-[(1-phenylcyclopentyl)methyl]ureas with enhanced hypocholesterolemic activity.

Trivedi BK, Purchase TS, Holmes A, Augelli-Szafran CE, Essenburg AD, Hamelehle KL, Stanfield RL, Bousley RF, Krause BR.

J Med Chem. 1994 May 27;37(11):1652-9.

PMID:
8201599
6.

Divergent pharmacologic activities of PD 132301-2 and CL 277,082, urea inhibitors of acyl-CoA:cholesterol acyltransferase.

Krause BR, Black A, Bousley R, Essenburg A, Cornicelli J, Holmes A, Homan R, Kieft K, Sekerke C, Shaw-Hes MK, et al.

J Pharmacol Exp Ther. 1993 Nov;267(2):734-43.

PMID:
8246149
7.

Evaluation of two novel biochemicals on plasma and egg yolk lipid composition and laying hen performance.

Elkin RG, Freed M, Watkins BA, Srebnik M, Kieft KA, Newton RS.

Poult Sci. 1993 Mar;72(3):513-20.

PMID:
8464792
8.

Subacute toxicity of a novel inhibitor of acyl-CoA: cholesterol acyltransferase in beagle dogs.

Dominick MA, McGuire EJ, Reindel JF, Bobrowski WF, Bocan TM, Gough AW.

Fundam Appl Toxicol. 1993 Feb;20(2):217-24.

PMID:
8383621
9.
10.

ATP depletion is associated with cytotoxicity of a novel lipid regulator in guinea pig adrenocortical cells.

Vernetti LA, MacDonald JR, Wolfgang GH, Dominick MA, Pegg DG.

Toxicol Appl Pharmacol. 1993 Jan;118(1):30-8.

PMID:
8381566

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