Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 43

  • Filters activated: Toxicology. Clear all to show 116 items.
1.

Dehydrocostus lactone, a sesquiterpene from Saussurea lappa Clarke, suppresses allergic airway inflammation by binding to dimerized translationally controlled tumor protein.

Pyun H, Kang U, Seo EK, Lee K.

Phytomedicine. 2018 Apr 1;43:46-54. doi: 10.1016/j.phymed.2018.03.045. Epub 2018 Mar 19.

PMID:
29747753
2.

Dehydrocostus lactone induces prominent apoptosis in kidney distal tubular epithelial cells and interstitial fibroblasts along with cell cycle arrest in ovarian epithelial cells.

Singireesu SSNR, Mondal SK, Misra S, Yerramsetty S, K SB.

Biomed Pharmacother. 2018 Mar;99:956-969. doi: 10.1016/j.biopha.2018.01.099. Epub 2018 Feb 20.

PMID:
29710496
3.

Ethnobotany, phytochemistry and pharmacology of Arctotis arctotoides (L.f.) O. Hoffm.: A review.

Saleh-E-In MM, Van Staden J.

J Ethnopharmacol. 2018 Jun 28;220:294-320. doi: 10.1016/j.jep.2018.01.011. Epub 2018 Jan 11. Review.

PMID:
29331315
4.

Anti-allergic effects of sesquiterpene lactones from Saussurea costus (Falc.) Lipsch. determined using in vivo and in vitro experiments.

Lee BK, Park SJ, Nam SY, Kang S, Hwang J, Lee SJ, Im DS.

J Ethnopharmacol. 2018 Mar 1;213:256-261. doi: 10.1016/j.jep.2017.11.018. Epub 2017 Nov 20.

PMID:
29158156
5.

Inhibition of TNF-α-Induced Inflammation by Sesquiterpene Lactones from Saussurea lappa and Semi-Synthetic Analogues.

Choodej S, Pudhom K, Mitsunaga T.

Planta Med. 2018 Mar;84(5):329-335. doi: 10.1055/s-0043-120115. Epub 2017 Sep 29.

PMID:
28962049
6.

Complexation of sesquiterpene lactones with cyclodextrins: synthesis and effects on their activities on parasitic weeds.

Cala A, Molinillo JMG, Fernández-Aparicio M, Ayuso J, Álvarez JA, Rubiales D, Macías FA.

Org Biomol Chem. 2017 Aug 9;15(31):6500-6510. doi: 10.1039/c7ob01394a.

PMID:
28745382
7.

Bioassay-guided isolation of dehydrocostus lactone from Saussurea lappa: A new targeted cytosolic thioredoxin reductase anticancer agent.

Yang M, Zhang J, Li Y, Han X, Gao K, Fang J.

Arch Biochem Biophys. 2016 Oct 1;607:20-6. doi: 10.1016/j.abb.2016.08.008. Epub 2016 Aug 18.

PMID:
27545438
8.

Neuroprotective effect and mechanism of Mu-Xiang-You-Fang on cerebral ischemia-reperfusion injury in rats.

Zhao Q, Cheng X, Wang X, Wang J, Zhu Y, Ma X.

J Ethnopharmacol. 2016 Nov 4;192:140-147. doi: 10.1016/j.jep.2016.07.016. Epub 2016 Jul 8.

PMID:
27396346
9.

Macelignan inhibits bee pathogenic fungi Ascophaera apis growth through HOG1 pathway.

Shin YK, Kim KY.

Braz J Med Biol Res. 2016 Jul 4;49(7). pii: S0100-879X2016000700607. doi: 10.1590/1414-431X20165313.

10.

Evaluation of protective effects of costunolide and dehydrocostuslactone on ethanol-induced gastric ulcer in mice based on multi-pathway regulation.

Zheng H, Chen Y, Zhang J, Wang L, Jin Z, Huang H, Man S, Gao W.

Chem Biol Interact. 2016 Apr 25;250:68-77. doi: 10.1016/j.cbi.2016.03.003. Epub 2016 Mar 10.

PMID:
26970604
11.

Dispirocyclopropyldehydrocostus lactone selectively inhibits acute myelogenous leukemia cells.

Ding YH, Gao X, Long J, Kuang BJ, Chen Y, Zhang Q.

Bioorg Med Chem Lett. 2016 Feb 15;26(4):1165-8. doi: 10.1016/j.bmcl.2016.01.046. Epub 2016 Jan 18.

PMID:
26832219
12.

Anti-allergic effects of sesquiterpene lactones from the root of Aucklandia lappa Decne.

Seo CS, Lim HS, Jeong SJ, Shin HK.

Mol Med Rep. 2015 Nov;12(5):7789-95. doi: 10.3892/mmr.2015.4342. Epub 2015 Sep 21.

PMID:
26398906
13.

The Genome-Wide Expression Profile of Saussurea lappa Extract on House Dust Mite-Induced Atopic Dermatitis in Nc/Nga Mice.

Lim HS, Ha H, Shin HK, Jeong SJ.

Mol Cells. 2015 Sep;38(9):765-72. doi: 10.14348/molcells.2015.0062. Epub 2015 Aug 21.

14.

Inhibition of inflammatory and proliferative responses of human keratinocytes exposed to the sesquiterpene lactones dehydrocostuslactone and costunolide.

Scarponi C, Butturini E, Sestito R, Madonna S, Cavani A, Mariotto S, Albanesi C.

PLoS One. 2014 Sep 16;9(9):e107904. doi: 10.1371/journal.pone.0107904. eCollection 2014.

15.

Growth inhibitory, bactericidal, and morphostructural effects of dehydrocostus lactone from Magnolia sieboldii Leaves on antibiotic-susceptible and -resistant strains of Helicobacter pylori.

Lee HK, Song HE, Lee HB, Kim CS, Koketsu M, Ngan LT, Ahn YJ.

PLoS One. 2014 Apr 18;9(4):e95530. doi: 10.1371/journal.pone.0095530. eCollection 2014.

16.

Gastrointestinal effect of methanol extract of Radix Aucklandiae and selected active substances on the transit activity of rat isolated intestinal strips.

Guo H, Zhang J, Gao W, Qu Z, Liu C.

Pharm Biol. 2014 Sep;52(9):1141-9. doi: 10.3109/13880209.2013.879601. Epub 2014 Mar 20.

PMID:
24649908
17.

Costunolide and Dehydrocostuslactone, two natural sesquiterpene lactones, ameliorate the inflammatory process associated to experimental pleurisy in mice.

Butturini E, Di Paola R, Suzuki H, Paterniti I, Ahmad A, Mariotto S, Cuzzocrea S.

Eur J Pharmacol. 2014 May 5;730:107-15. doi: 10.1016/j.ejphar.2014.02.031. Epub 2014 Mar 10.

PMID:
24625594
18.

Pharmacokinetic study on costunolide and dehydrocostuslactone after oral administration of traditional medicine Aucklandia lappa Decne. by LC/MS/MS.

Zhang J, Hu X, Gao W, Qu Z, Guo H, Liu Z, Liu C.

J Ethnopharmacol. 2014;151(1):191-7. doi: 10.1016/j.jep.2013.10.024. Epub 2013 Nov 8.

PMID:
24216164
19.

A platform for fast screening potential anti-breast cancer compounds in traditional Chinese medicines.

Peng ZX, Wang Y, Gu X, Wen YY, Yan C.

Biomed Chromatogr. 2013 Dec;27(12):1759-66. doi: 10.1002/bmc.2990. Epub 2013 Jul 25.

PMID:
23893711
20.

Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells.

Lohberger B, Rinner B, Stuendl N, Kaltenegger H, Steinecker-Frohnwieser B, Bernhart E, Bonyadi Rad E, Weinberg AM, Leithner A, Bauer R, Kretschmer N.

PLoS One. 2013 Jun 14;8(6):e66300. doi: 10.1371/journal.pone.0066300. Print 2013.

Supplemental Content

Loading ...
Support Center